-
1
-
-
0037043658
-
Inflammatory bowel disease
-
Podolsky DK. Inflammatory bowel disease. N Engl J Med. 2002;347: 417-429.
-
(2002)
N. Engl. J. Med.
, vol.347
, pp. 417-429
-
-
Podolsky, D.K.1
-
2
-
-
0001947699
-
Immunological disease of the gastrointestinal tract
-
Rich RR, ed. St. Louis, MO: Mosby
-
Strober W, Neurath MF. Immunological disease of the gastrointestinal tract. In: Rich RR, ed. Clinical Immunology. St. Louis, MO: Mosby; 1995:1401-1428.
-
(1995)
Clinical Immunology
, pp. 1401-1428
-
-
Strober, W.1
Neurath, M.F.2
-
3
-
-
0037022008
-
Crohn's disease
-
Shanahan F. Crohn's disease. Lancet. 2002;359:62-69.
-
(2002)
Lancet
, vol.359
, pp. 62-69
-
-
Shanahan, F.1
-
4
-
-
0033981670
-
Therapy of inflammatory bowel disease
-
Sands BE. Therapy of inflammatory bowel disease. Gastroenterology. 2000;118:S68-S82.
-
(2000)
Gastroenterology
, vol.118
-
-
Sands, B.E.1
-
7
-
-
0036276331
-
Crohn's disease - The role of nutritional therapy
-
Forbes A. Crohn's disease - the role of nutritional therapy. Aliment Pharmacol Ther. 2002;16:S48-S52.
-
(2002)
Aliment Pharmacol. Ther.
, vol.16
-
-
Forbes, A.1
-
8
-
-
18544408493
-
Development of an oral drug delivery system targeting immune-regulating cells in experimental inflammatory bowel disease: A new therapeutic strategy
-
Nakase H, Okazaki K, Tabata Y, et al. Development of an oral drug delivery system targeting immune-regulating cells in experimental inflammatory bowel disease: a new therapeutic strategy. J Pharmacol Exp Ther. 2000;292:15-21.
-
(2000)
J. Pharmacol. Exp. Ther.
, vol.292
, pp. 15-21
-
-
Nakase, H.1
Okazaki, K.2
Tabata, Y.3
-
9
-
-
0029923360
-
A review of immune modifier therapy for inflammatory bowel disease: Azathioprine, 6-mercaptopurine, cyclosporine, and methotrexate
-
Sandborn WJ. A review of immune modifier therapy for inflammatory bowel disease: azathioprine, 6-mercaptopurine, cyclosporine, and methotrexate. Am J Gastroenterol. 1996;91:423-433.
-
(1996)
Am. J. Gastroenterol.
, vol.91
, pp. 423-433
-
-
Sandborn, W.J.1
-
10
-
-
0031057872
-
Type 1 T-helper cell predominance and interleukin-12 expression in the gut of patients with Crohn's disease
-
Parronchi P, Romagnani P, Annunziato F, et al. Type 1 T-helper cell predominance and interleukin-12 expression in the gut of patients with Crohn's disease. Am J Pathol. 1997;150:823-832.
-
(1997)
Am. J. Pathol.
, vol.150
, pp. 823-832
-
-
Parronchi, P.1
Romagnani, P.2
Annunziato, F.3
-
11
-
-
0035116091
-
Inflammatory bowel disease: Immunodiagnostics, immunotherapeutics, and ecotherapeutics
-
Shanahan F. Inflammatory bowel disease: immunodiagnostics, immunotherapeutics, and ecotherapeutics. Gastroenterology. 2001;120:622-635.
-
(2001)
Gastroenterology
, vol.120
, pp. 622-635
-
-
Shanahan, F.1
-
12
-
-
0036897225
-
Infliximab in the treatment of Crohn's disease: A user's guide for clinicians
-
Sandborn WJ, Hanauer SB. Infliximab in the treatment of Crohn's disease: a user's guide for clinicians. Am J Gastroenterol. 2002;97:2962-2972.
-
(2002)
Am. J. Gastroenterol.
, vol.97
, pp. 2962-2972
-
-
Sandborn, W.J.1
Hanauer, S.B.2
-
13
-
-
0033125226
-
Antitumor necrosis factor therapy for inflammatory bowel disease: A review of agents, pharmacology, clinical results, and safety
-
Sandborn WJ, Hanauer SB. Antitumor necrosis factor therapy for inflammatory bowel disease: a review of agents, pharmacology, clinical results, and safety. Inflamm Bowel Dis. 1999;5:119-133.
-
(1999)
Inflamm. Bowel Dis.
, vol.5
, pp. 119-133
-
-
Sandborn, W.J.1
Hanauer, S.B.2
-
14
-
-
0037243234
-
Anti-interleukin-6 therapy for Crohn's disease
-
Ito H. Anti-interleukin-6 therapy for Crohn's disease. Curr Pharm Des. 2003;9:295-305.
-
(2003)
Curr. Pharm. Des.
, vol.9
, pp. 295-305
-
-
Ito, H.1
-
16
-
-
0033071539
-
Effect of leukocytapheresis therapy using a leukocyte removal filter in Crohn's disease
-
Kosaka T, Sawada K, Ohnishi K, et al. Effect of leukocytapheresis therapy using a leukocyte removal filter in Crohn's disease. Intern Med. 1999;38:102-111.
-
(1999)
Intern. Med.
, vol.38
, pp. 102-111
-
-
Kosaka, T.1
Sawada, K.2
Ohnishi, K.3
-
17
-
-
0037285976
-
Granulocytapheresis for Crohn's disease: A report on seven refractory patients
-
Matsui T, Nishimura T, Matake H, et al. Granulocytapheresis for Crohn's disease: a report on seven refractory patients. Am J Gastroenterol. 2003; 98:511-512.
-
(2003)
Am. J. Gastroenterol.
, vol.98
, pp. 511-512
-
-
Matsui, T.1
Nishimura, T.2
Matake, H.3
-
18
-
-
0028943870
-
Design, synthesis, and structure-activity relationships of 2-substituted-2-amino-1, 3-propanodiols: Discovery of a novel immunosuppressant, FTY720
-
Adachi K, Kohara T, Arita M, et al. Design, synthesis, and structure-activity relationships of 2-substituted-2-amino-1, 3-propanodiols: discovery of a novel immunosuppressant, FTY720. Bioorg Med Chem Lett. 1995;5:853-856.
-
(1995)
Bioorg. Med. Chem. Lett.
, vol.5
, pp. 853-856
-
-
Adachi, K.1
Kohara, T.2
Arita, M.3
-
19
-
-
0028936902
-
Simple compounds, 2-substituted-2-amino-1, 3-propanodiols have potent immunosuppressive activity
-
Fujita T, Yoneta M, Hirose R, et al. Simple compounds, 2-substituted-2-amino-1, 3-propanodiols have potent immunosuppressive activity. Bioorg Med Chem Lett. 1995;5:847-852.
-
(1995)
Bioorg. Med. Chem. Lett.
, vol.5
, pp. 847-852
-
-
Fujita, T.1
Yoneta, M.2
Hirose, R.3
-
20
-
-
0030049234
-
A novel immunosuppressant, FTY720, with a unique mechanism of action, induces long-term graft acceptance in rat and dog allotransplantation
-
Suzuki S, Enosawa S, Kakefuda T, et al. A novel immunosuppressant, FTY720, with a unique mechanism of action, induces long-term graft acceptance in rat and dog allotransplantation. Transplantation. 1996;6:200-205.
-
(1996)
Transplantation
, vol.6
, pp. 200-205
-
-
Suzuki, S.1
Enosawa, S.2
Kakefuda, T.3
-
21
-
-
0035671314
-
FTY720, a novel transplantation drug, modulates lymphocyte migratory responses to chemokines
-
Chen S, Bacon KB, Garcia G, et al. FTY720, a novel transplantation drug, modulates lymphocyte migratory responses to chemokines. Transplant Proc. 2001;33:3057-3063.
-
(2001)
Transplant. Proc.
, vol.33
, pp. 3057-3063
-
-
Chen, S.1
Bacon, K.B.2
Garcia, G.3
-
22
-
-
0027521572
-
Interleukin-10-deficient mice develop chronic enterocolitis
-
Kuhn R, Lohler J, Rennick D, et al. Interleukin-10-deficient mice develop chronic enterocolitis. Cell. 1993;75:263-274.
-
(1993)
Cell
, vol.75
, pp. 263-274
-
-
Kuhn, R.1
Lohler, J.2
Rennick, D.3
-
23
-
-
0002020505
-
Role of the intestinal microflora in pathogenesis and complications
-
Scholmerich JH, Goebell W, Kruis W, Hohenberger W, eds. London, England: Kluwer Academic
-
Sartor RB. Role of the intestinal microflora in pathogenesis and complications. In: Scholmerich JH, Goebell W, Kruis W, Hohenberger W, eds. Inflammatory Bowel Diseases: Pathophysiology as Basis of Treatment. London, England: Kluwer Academic, 1992;175-187.
-
(1992)
Inflammatory Bowel Diseases: Pathophysiology As Basis of Treatment
, pp. 175-187
-
-
Sartor, R.B.1
-
24
-
-
0029994954
-
Gamma/delta T cell-deficient mice have impaired mucosal immunoglobulin A responses
-
Fujihashi K, McGhee JR, Kweon MN, et al. Gamma/delta T cell-deficient mice have impaired mucosal immunoglobulin A responses. J Exp Med. 1996;183:1929-1935.
-
(1996)
J. Exp. Med.
, vol.183
, pp. 1929-1935
-
-
Fujihashi, K.1
McGhee, J.R.2
Kweon, M.N.3
-
25
-
-
0031004877
-
CD4+ T-cell population mediates development of inflammatory bowel disease in T-cell receptor alpha chain-deficient mice
-
Takahashi I, Kiyono H, Hamada S. CD4+ T-cell population mediates development of inflammatory bowel disease in T-cell receptor alpha chain-deficient mice. Gastroenterology. 1997;112:1876-1886.
-
(1997)
Gastroenterology
, vol.112
, pp. 1876-1886
-
-
Takahashi, I.1
Kiyono, H.2
Hamada, S.3
-
26
-
-
0032820282
-
Alteration of interleukin 4 production results in the inhibition of T helper type 2 cell-dominated inflammatory bowel disease in T cell receptor alpha chain-deficient mice
-
Iijima H, Takahashi I, Kishi D, et al. Alteration of interleukin 4 production results in the inhibition of T helper type 2 cell-dominated inflammatory bowel disease in T cell receptor alpha chain-deficient mice. J Exp Med. 1999;190:607-615.
-
(1999)
J. Exp. Med.
, vol.190
, pp. 607-615
-
-
Iijima, H.1
Takahashi, I.2
Kishi, D.3
-
27
-
-
0033571441
-
Nonlymphocyte-derived tumor necrosis factor is required for induction of colitis in recombination activating gene (RAG)2(-/-) mice upon transfer of CD4(+)CD45RB(hi) T cells
-
Corazza N, Eichenberger S, Eugster HP, et al. Nonlymphocyte-derived tumor necrosis factor is required for induction of colitis in recombination activating gene (RAG)2(-/-) mice upon transfer of CD4(+)CD45RB(hi) T cells. J Exp Med. 1999;190:1479-1492.
-
(1999)
J. Exp. Med.
, vol.190
, pp. 1479-1492
-
-
Corazza, N.1
Eichenberger, S.2
Eugster, H.P.3
-
28
-
-
0031781603
-
Inflammatory bowel disease: Etiology and pathogenesis
-
Fiocchi C. Inflammatory bowel disease: etiology and pathogenesis. Gastroenterology. 1998;115:182-205.
-
(1998)
Gastroenterology
, vol.115
, pp. 182-205
-
-
Fiocchi, C.1
-
29
-
-
0030018186
-
T helper cell 1-type CD4+ T cells, but not B cells, mediate colitis in interleukin 10-deficient mice
-
Davidson NJ, Leach MW, Fort MM, et al. T helper cell 1-type CD4+ T cells, but not B cells, mediate colitis in interleukin 10-deficient mice. J Exp Med. 1996;184:241-251.
-
(1996)
J. Exp. Med.
, vol.184
, pp. 241-251
-
-
Davidson, N.J.1
Leach, M.W.2
Fort, M.M.3
-
30
-
-
0032530697
-
IL-12, but not IFN-gamma, plays a major role in sustaining the chronic phase of colitis in IL-10-deficient mice
-
Davidson NJ, Hudak SA, Lesley RE, et al. IL-12, but not IFN-gamma, plays a major role in sustaining the chronic phase of colitis in IL-10-deficient mice. J Immunol. 1998;161:3143-3149.
-
(1998)
J. Immunol.
, vol.161
, pp. 3143-3149
-
-
Davidson, N.J.1
Hudak, S.A.2
Lesley, R.E.3
-
31
-
-
0029813545
-
Enterocolitis and colon cancer in interleukin-10-deficient mice are associated with aberrant cytokine production and CD4(+) TH1-like responses
-
Berg DJ, Davidson N, Kuhn P, et al. Enterocolitis and colon cancer in interleukin-10-deficient mice are associated with aberrant cytokine production and CD4(+) TH1-like responses. J Clin Invest. 1996;98:1010-1020.
-
(1996)
J. Clin. Invest.
, vol.98
, pp. 1010-1020
-
-
Berg, D.J.1
Davidson, N.2
Kuhn, P.3
-
33
-
-
0035876906
-
The prevention and treatment of murine colitis using gene therapy with adenoviral vectors encoding IL-10
-
Lindsay JO, Ciesielski CJ, Scheinin T, et al. The prevention and treatment of murine colitis using gene therapy with adenoviral vectors encoding IL-10. J Immunol. 2001;166:7625-7633.
-
(2001)
J. Immunol.
, vol.166
, pp. 7625-7633
-
-
Lindsay, J.O.1
Ciesielski, C.J.2
Scheinin, T.3
-
34
-
-
0030001675
-
Lymphocyte homing and homeostasis
-
Butcher EC, Picker LJ. Lymphocyte homing and homeostasis. Science. 1996;272:60-66.
-
(1996)
Science
, vol.272
, pp. 60-66
-
-
Butcher, E.C.1
Picker, L.J.2
-
35
-
-
0035376098
-
The mucosal immune system: From specialized immune defense to inflammation and allergy
-
Kiyono H, Kweon MN, Hiroi T, et al. The mucosal immune system: from specialized immune defense to inflammation and allergy. Acta Odontol Scand. 2001;59:145-153.
-
(2001)
Acta Odontol. Scand.
, vol.59
, pp. 145-153
-
-
Kiyono, H.1
Kweon, M.N.2
Hiroi, T.3
-
36
-
-
0035061328
-
Mucosal immune network in the gut for the control of infectious diseases
-
Iijima H, Takahashi I, Kiyono H. Mucosal immune network in the gut for the control of infectious diseases. Rev Med Virol. 2001;11:117-133.
-
(2001)
Rev. Med. Virol.
, vol.11
, pp. 117-133
-
-
Iijima, H.1
Takahashi, I.2
Kiyono, H.3
-
37
-
-
0030806495
-
The immune system in inflammatory bowel disease
-
Fiocchi C. The immune system in inflammatory bowel disease. Acta Gastroenterol Belg. 1997;60:156-162.
-
(1997)
Acta Gastroenterol. Belg.
, vol.60
, pp. 156-162
-
-
Fiocchi, C.1
-
39
-
-
0035313991
-
Chemokines in lymphopoiesis and lymphoid organ development
-
Ansel KM, Cyster JG. Chemokines in lymphopoiesis and lymphoid organ development. Curr Opin Immunol. 2001;13(2):172-179.
-
(2001)
Curr. Opin. Immunol.
, vol.13
, Issue.2
, pp. 172-179
-
-
Ansel, K.M.1
Cyster, J.G.2
-
40
-
-
0031092633
-
Monoclonal antibodies specific for beta 7 integrin and mucosal addressin cell adhesion molecule-1 (MAd-CAM-1) reduce inflammation in the colon of scid mice reconstituted with CD45RBhigh CD4+ T cells
-
Picarella D, Hurlbut P, Rottman J, et al. Monoclonal antibodies specific for beta 7 integrin and mucosal addressin cell adhesion molecule-1 (MAd-CAM-1) reduce inflammation in the colon of scid mice reconstituted with CD45RBhigh CD4+ T cells. Immunology. 1997;158:2099-2106.
-
(1997)
Immunology
, vol.158
, pp. 2099-2106
-
-
Picarella, D.1
Hurlbut, P.2
Rottman, J.3
-
41
-
-
0039701205
-
Administration of mAb against alpha E beta 7 prevents and ameliorates immunization-induced colitis in IL-2-/- mice
-
Ludviksson BR, Strober W, Nishikomori R, et al. Administration of mAb against alpha E beta 7 prevents and ameliorates immunization-induced colitis in IL-2-/- mice. J Immunol. 1999;62:4975-4982.
-
(1999)
J. Immunol.
, vol.62
, pp. 4975-4982
-
-
Ludviksson, B.R.1
Strober, W.2
Nishikomori, R.3
-
43
-
-
0032525049
-
FTY720, a novel immunosuppressant, induces sequestration of circulating mature lymphocytes by acceleration of lymphocyte homing in rats. I. FTY720 selectively decreases the number of circulating mature lymphocytes by acceleration of lymphocyte homing
-
Chiba K, Yanagawa Y, Masubuchi Y, et al. FTY720, a novel immunosuppressant, induces sequestration of circulating mature lymphocytes by acceleration of lymphocyte homing in rats. I. FTY720 selectively decreases the number of circulating mature lymphocytes by acceleration of lymphocyte homing. J Immunol. 1998;160:5037-5044.
-
(1998)
J. Immunol.
, vol.160
, pp. 5037-5044
-
-
Chiba, K.1
Yanagawa, Y.2
Masubuchi, Y.3
-
44
-
-
0031741847
-
FTY720, a novel immunosuppressant, induces sequestration of circulating mature lymphocytes by acceleration of lymphocyte homing in rats, III. Increase in frequency of CD62L-positive T cells in Peyer's patches by FTY720-induced lymphocyte homing
-
Yanagawa Y, Masubuchi Y, Chiba K. FTY720, a novel immunosuppressant, induces sequestration of circulating mature lymphocytes by acceleration of lymphocyte homing in rats, III. Increase in frequency of CD62L-positive T cells in Peyer's patches by FTY720-induced lymphocyte homing. Immunology. 1998;95:591-594.
-
(1998)
Immunology
, vol.95
, pp. 591-594
-
-
Yanagawa, Y.1
Masubuchi, Y.2
Chiba, K.3
-
45
-
-
0034120178
-
FTY720 immunosuppression impairs effector T cell peripheral homing without affecting induction, expansion, and memory
-
Pinschewer DD, Ochsenbein AF, Odermatt B, et al. FTY720 immunosuppression impairs effector T cell peripheral homing without affecting induction, expansion, and memory. J Immunol. 2000;164:5761-5770.
-
(2000)
J. Immunol.
, vol.164
, pp. 5761-5770
-
-
Pinschewer, D.D.1
Ochsenbein, A.F.2
Odermatt, B.3
-
46
-
-
0034661482
-
Sphingosine 1-phosphate signalling in mammalian cells
-
Pyne S, Pyne NJ. Sphingosine 1-phosphate signalling in mammalian cells. Biochem J. 2000;349(Pt 2):385-402.
-
(2000)
Biochem. J
, vol.349
, Issue.PART 2
, pp. 385-402
-
-
Pyne, S.1
Pyne, N.J.2
-
47
-
-
0037077308
-
The immune modulator FTY720 targets sphingosine 1-phosphate receptors
-
Brinkmann V, Davis MD, Heise CE, et al. The immune modulator FTY720 targets sphingosine 1-phosphate receptors. J Biol Chem. 2002; 277:21453-21457.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 21453-21457
-
-
Brinkmann, V.1
Davis, M.D.2
Heise, C.E.3
-
48
-
-
0037066466
-
Alteration of lymphocyte trafficking by sphingosine-1-phosphate receptor agonists
-
Mandala S, Hajdu R, Bergstrom J, et al. Alteration of lymphocyte trafficking by sphingosine-1-phosphate receptor agonists. Science. 2002;296: 346-349.
-
(2002)
Science
, vol.296
, pp. 346-349
-
-
Mandala, S.1
Hajdu, R.2
Bergstrom, J.3
-
49
-
-
0037326647
-
Elimination of local macrophages in intestine prevents chronic colitis in interleukin-10-deficient mice
-
Watanabe N, Ikuta K, Okazaki K, et al. Elimination of local macrophages in intestine prevents chronic colitis in interleukin-10-deficient mice. Dig Dis Sci. 2003;48:408-414.
-
(2003)
Dig. Dis. Sci.
, vol.48
, pp. 408-414
-
-
Watanabe, N.1
Ikuta, K.2
Okazaki, K.3
-
50
-
-
0029857032
-
A new immunosuppressant, FTY720, induces bcl-2-associated apoptotic cell death in human lymphocytes
-
Suzuki S, Li XK, Enosawa S, et al. A new immunosuppressant, FTY720, induces bcl-2-associated apoptotic cell death in human lymphocytes. Immunology. 1996;89:518-523.
-
(1996)
Immunology
, vol.89
, pp. 518-523
-
-
Suzuki, S.1
Li, X.K.2
Enosawa, S.3
-
51
-
-
0034839215
-
Activation of caspases and mitochondria in FTY720-mediated apoptosis in human T cell line Jurkat
-
Fujino M, Li XK, Guo L, et al. Activation of caspases and mitochondria in FTY720-mediated apoptosis in human T cell line Jurkat. Int Immunopharmacol. 2001;1:2011-2021.
-
(2001)
Int. Immunopharmacol.
, vol.1
, pp. 2011-2021
-
-
Fujino, M.1
Li, X.K.2
Guo, L.3
-
52
-
-
0030245686
-
Induction of selective cell death targeting on mature T-lymphocytes in rats by a novel immunosuppressant, FTY720
-
Enosawa S, Suzuki S, Kakefuda T, et al. Induction of selective cell death targeting on mature T-lymphocytes in rats by a novel immunosuppressant, FTY720. Immunopharmacology. 1996;34:171-179.
-
(1996)
Immunopharmacology
, vol.34
, pp. 171-179
-
-
Enosawa, S.1
Suzuki, S.2
Kakefuda, T.3
-
53
-
-
0035114740
-
Induction of lymphocyte apoptosis in rat liver allograft with ongoing rejection by FTY720
-
Li XK, Tamura A, Fujino M, et al. Induction of lymphocyte apoptosis in rat liver allograft with ongoing rejection by FTY720. Clin Exp Immunol. 2001;123:331-339.
-
(2001)
Clin. Exp. Immunol.
, vol.123
, pp. 331-339
-
-
Li, X.K.1
Tamura, A.2
Fujino, M.3
-
54
-
-
0032890396
-
Effector and regulatory lymphoid cells and cytokines in mucosal sites
-
MacDonald TT. Effector and regulatory lymphoid cells and cytokines in mucosal sites. Curr Top Microbiol Immunol. 1999;236:113-135.
-
(1999)
Curr. Top. Microbiol. Immunol.
, vol.236
, pp. 113-135
-
-
MacDonald, T.T.1
|