메뉴 건너뛰기




Volumn 27, Issue , 1996, Pages 351-367

Perturbation of cell cycle regulators in human cancer

Author keywords

[No Author keywords available]

Indexed keywords

CYCLINE;

EID: 0029855312     PISSN: 02612429     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (95)

References (129)
  • 1
    • 0027523623 scopus 로고
    • Independent regulation of human D-type cyclin gene expression during G1 phase in primary T lymphocytes
    • Ajchenbaum F, Ando K, DeCaprio JA and Griffin JD (1993) Independent regulation of human D-type cyclin gene expression during G1 phase in primary T lymphocytes. Journal of Biological Chemistry 268 4113-4119
    • (1993) Journal of Biological Chemistry , vol.268 , pp. 4113-4119
    • Ajchenbaum, F.1    Ando, K.2    DeCaprio, J.A.3    Griffin, J.D.4
  • 2
    • 0028959644 scopus 로고
    • Cdk4 integrates growth stimulatory and inhibitory signals during G1 phase of hematopoietic cells
    • Ando K and Griffin JD (1995) Cdk4 integrates growth stimulatory and inhibitory signals during G1 phase of hematopoietic cells. Oncogene 10 751-755
    • (1995) Oncogene , vol.10 , pp. 751-755
    • Ando, K.1    Griffin, J.D.2
  • 4
    • 0028943438 scopus 로고
    • Overexpression of cyclin D1 blocks proliferation of normal diploid fibroblasts
    • Atadja P, Wong H, Veillete C and Riabowol K (1995) Overexpression of cyclin D1 blocks proliferation of normal diploid fibroblasts. Experimental Cell Research 217 205-216
    • (1995) Experimental Cell Research , vol.217 , pp. 205-216
    • Atadja, P.1    Wong, H.2    Veillete, C.3    Riabowol, K.4
  • 7
    • 0028967830 scopus 로고
    • Cyclin D1 oncoprotein aberrantly accumulates in malignancies of diverse histogenesis
    • Bartkova J, Lukas J, Strauss M and Bartek J (1995) Cyclin D1 oncoprotein aberrantly accumulates in malignancies of diverse histogenesis. Oncogene 10 775-778
    • (1995) Oncogene , vol.10 , pp. 775-778
    • Bartkova, J.1    Lukas, J.2    Strauss, M.3    Bartek, J.4
  • 8
    • 0028928540 scopus 로고
    • A mutant p21 cyclin-dependent kinase inhibitor isolated from a Burkitt's lymphoma
    • Bhatia K, Fan S, Spangler G et al (1995) A mutant p21 cyclin-dependent kinase inhibitor isolated from a Burkitt's lymphoma. Cancer Research 55 1431-1435
    • (1995) Cancer Research , vol.55 , pp. 1431-1435
    • Bhatia, K.1    Fan, S.2    Spangler, G.3
  • 9
    • 0028778176 scopus 로고
    • Open questions on p16
    • Bonetta L (1994) Open questions on p16. Nature 370 180
    • (1994) Nature , vol.370 , pp. 180
    • Bonetta, L.1
  • 11
    • 0027280084 scopus 로고
    • Expression and amplification of cyclin genes in human breast cancer
    • Buckley MF, Sweeney KJE, Hamilton JA et al (1993) Expression and amplification of cyclin genes in human breast cancer. Oncogene 8 2127-2133
    • (1993) Oncogene , vol.8 , pp. 2127-2133
    • Buckley, M.F.1    Sweeney, K.J.E.2    Hamilton, J.A.3
  • 12
    • 0029140452 scopus 로고
    • CAK-handed kinase activation
    • Clarke PR (1995) CAK-handed kinase activation. Current Biology 5 40-42
    • (1995) Current Biology , vol.5 , pp. 40-42
    • Clarke, P.R.1
  • 14
    • 0027980180 scopus 로고
    • Chromosomal mapping of human CDK2, CDK4, and CDK5 cell cycle kinase genes
    • Demetrick DJ, Zhang H and Beach DH (1994) Chromosomal mapping of human CDK2, CDK4, and CDK5 cell cycle kinase genes. Cytogenetics and Cell Genetics 66 72-74
    • (1994) Cytogenetics and Cell Genetics , vol.66 , pp. 72-74
    • Demetrick, D.J.1    Zhang, H.2    Beach, D.H.3
  • 15
    • 0028978183 scopus 로고
    • CIP1/WAF1 Underg0 normal development, but are defective in G1 checkpoint control
    • CIP1/WAF1 Underg0 normal development, but are defective in G1 checkpoint control. Cell 82 675-684
    • (1995) Cell , vol.82 , pp. 675-684
    • Deng, C.1    Zhang, P.2    Harper, J.W.3    Elledge, S.J.4    Leder, P.5
  • 16
    • 0027204555 scopus 로고
    • Physical interaction of the retinoblastoma protein with human D cyclins
    • Dowdy SF, Hinds PW, Louie K, Reed SI, Arnold A and Weinberg RA (1993) Physical interaction of the retinoblastoma protein with human D cyclins. Cell 73 499-511
    • (1993) Cell , vol.73 , pp. 499-511
    • Dowdy, S.F.1    Hinds, P.W.2    Louie, K.3    Reed, S.I.4    Arnold, A.5    Weinberg, R.A.6
  • 18
    • 0029044951 scopus 로고
    • The transcription factor E2F is required for S phase during Drosophila embryogenesis
    • Duronio RJ, O'Farrell PH, Xie J-E, Brook A and Dyson N (1995) The transcription factor E2F is required for S phase during Drosophila embryogenesis. Genes and Development 9 1445-1455
    • (1995) Genes and Development , vol.9 , pp. 1445-1455
    • Duronio, R.J.1    O'Farrell, P.H.2    Xie, J.-E.3    Brook, A.4    Dyson, N.5
  • 19
    • 0027422907 scopus 로고
    • Chromosome 9 short arm deletions in malignant diseases
    • Einhorn S and Heyman M (1993) Chromosome 9 short arm deletions in malignant diseases. Leukemia and Lymphoma 11 191-196
    • (1993) Leukemia and Lymphoma , vol.11 , pp. 191-196
    • Einhorn, S.1    Heyman, M.2
  • 20
    • 0027359827 scopus 로고
    • WAFI, a potential mediator of p53 tumor suppression
    • El-Deiry WS, Tokino T, Velculescu VE et al (1993) WAFI, a potential mediator of p53 tumor suppression. Cell 75 817-825
    • (1993) Cell , vol.75 , pp. 817-825
    • El-Deiry, W.S.1    Tokino, T.2    Velculescu, V.E.3
  • 21
    • 0028075611 scopus 로고
    • Cdk inhibitors: On the threshold of checkpoints and development
    • Elledge SJ and Harper JW (1994) Cdk inhibitors: on the threshold of checkpoints and development. Current Opinion in Cell Biology 6 847-852
    • (1994) Current Opinion in Cell Biology , vol.6 , pp. 847-852
    • Elledge, S.J.1    Harper, J.W.2
  • 22
    • 0027229136 scopus 로고
    • Functional interactions of the retinoblastoma protein with mammalian D-type cyclins
    • Ewen ME, Sluss HK, Sherr CJ, Matsushime H, Kato J and Livingston DM (1993) Functional interactions of the retinoblastoma protein with mammalian D-type cyclins. Cell 73 487-497
    • (1993) Cell , vol.73 , pp. 487-497
    • Ewen, M.E.1    Sluss, H.K.2    Sherr, C.J.3    Matsushime, H.4    Kato, J.5    Livingston, D.M.6
  • 24
    • 0027981476 scopus 로고
    • Cdk-interacting protein 1 directly binds with proliferating cell nuclear antigen and inhibits DNA replication catalyzed by the DNA polymerase δ holoenzyme
    • Flores-Rozas H, Kelman Z, Dean FB et al (1994) Cdk-interacting protein 1 directly binds with proliferating cell nuclear antigen and inhibits DNA replication catalyzed by the DNA polymerase δ holoenzyme. Proceedings of the National Academy of Sciences of the USA 91 8655-8659
    • (1994) Proceedings of the National Academy of Sciences of the USA , vol.91 , pp. 8655-8659
    • Flores-Rozas, H.1    Kelman, Z.2    Dean, F.B.3
  • 25
    • 0028845577 scopus 로고
    • Somatic mutations of the WAF1/CIP1 gene in primary prostatic cancer
    • Gao X, Chen YQ, Wu N et al (1995) Somatic mutations of the WAF1/CIP1 gene in primary prostatic cancer. Oncogene 11 1395-1398
    • (1995) Oncogene , vol.11 , pp. 1395-1398
    • Gao, X.1    Chen, Y.Q.2    Wu, N.3
  • 26
    • 0029986337 scopus 로고    scopus 로고
    • Regulation of cyclin E transcription by E2Fs and retinoblastoma protein
    • Geng Y, Eaton EN, Picón M et al (1996) Regulation of cyclin E transcription by E2Fs and retinoblastoma protein. Oncogene 12 1173-1180
    • (1996) Oncogene , vol.12 , pp. 1173-1180
    • Geng, Y.1    Eaton, E.N.2    Picón, M.3
  • 27
    • 0028331092 scopus 로고
    • Amplification and overexpression of cyclin D1 in breast cancer detected by immunohistochemical staining
    • Gillett C, Fantl R, Fisher C et al (1994) Amplification and overexpression of cyclin D1 in breast cancer detected by immunohistochemical staining. Cancer Research 54 1812-1817
    • (1994) Cancer Research , vol.54 , pp. 1812-1817
    • Gillett, C.1    Fantl, R.2    Fisher, C.3
  • 29
    • 0028875205 scopus 로고
    • Methylation of the 5′ CpG island of the p16/CDKN2 tumor suppressor gene in normal and transformed human tissues correlates with gene silencing
    • Gonzalez-Zulueta M, Bender CM, Yang AS et al (1995) Methylation of the 5′ CpG island of the p16/CDKN2 tumor suppressor gene in normal and transformed human tissues correlates with gene silencing. Cancer Research 55 4531-4535
    • (1995) Cancer Research , vol.55 , pp. 4531-4535
    • Gonzalez-Zulueta, M.1    Bender, C.M.2    Yang, A.S.3
  • 30
    • 0027308761 scopus 로고
    • Molecular characterization of the retinoblastoma susceptibility gene
    • Goodrich DW and Lee W-H (1993) Molecular characterization of the retinoblastoma susceptibility gene. Biochimica et Biophysica Acta 1155 43-61
    • (1993) Biochimica et Biophysica Acta , vol.1155 , pp. 43-61
    • Goodrich, D.W.1    Lee, W.-H.2
  • 31
    • 0027731971 scopus 로고
    • Inhibition of CDK2 activity in vivo by an associated 20K regulatory subunit
    • Gu Y, Turck CW and Morgan DO (1993) Inhibition of CDK2 activity in vivo by an associated 20K regulatory subunit. Nature 366 707-710
    • (1993) Nature , vol.366 , pp. 707-710
    • Gu, Y.1    Turck, C.W.2    Morgan, D.O.3
  • 32
    • 0028582034 scopus 로고
    • INK4/MTS2-related CDK6 inhibitor, correlates with wild-type pRb function
    • INK4/MTS2-related CDK6 inhibitor, correlates with wild-type pRb function. Genes and Development 8 2939-2952
    • (1994) Genes and Development , vol.8 , pp. 2939-2952
    • Guan, K.-L.1    Jenkins, C.W.2    Li, Y.3
  • 33
    • 0029921317 scopus 로고    scopus 로고
    • Genetic alterations of cyclins, cyclin-dependent kinases, and Cdk inhibitors in human cancer
    • Hall M and Peters G (1996) Genetic alterations of cyclins, cyclin-dependent kinases, and Cdk inhibitors in human cancer. Advances in Cancer Research 68 67-108
    • (1996) Advances in Cancer Research , vol.68 , pp. 67-108
    • Hall, M.1    Peters, G.2
  • 34
    • 0028907553 scopus 로고
    • Stable overexpression of cyclin D1 in a human mammary epithelial cell line prolongs the S-phase and inhibits growth
    • Han EK-H, Sgambato A, Jiang W et al (1995) Stable overexpression of cyclin D1 in a human mammary epithelial cell line prolongs the S-phase and inhibits growth. Oncogene 10 953-961
    • (1995) Oncogene , vol.10 , pp. 953-961
    • Han, E.K.-H.1    Sgambato, A.2    Jiang, W.3
  • 35
    • 0027223314 scopus 로고
    • The Vin-1 gene, identified by provirus insertional mutagenesis, is the cyclin D2
    • Hanna Z, Janowski M, Tremblay P et al (1993) The Vin-1 gene, identified by provirus insertional mutagenesis, is the cyclin D2. Oncogene 8 1661-1666
    • (1993) Oncogene , vol.8 , pp. 1661-1666
    • Hanna, Z.1    Janowski, M.2    Tremblay, P.3
  • 37
    • 0027496935 scopus 로고
    • The p21 Cdk-interacting protein Cipl is a potent inhibitor of G1 cyclin-dependent kinases
    • Harper JW, Adami GR, Wei N, Keyomarsi K and Elledge SJ (1993) The p21 Cdk-interacting protein Cipl is a potent inhibitor of G1 cyclin-dependent kinases. Cell 75 805-816
    • (1993) Cell , vol.75 , pp. 805-816
    • Harper, J.W.1    Adami, G.R.2    Wei, N.3    Keyomarsi, K.4    Elledge, S.J.5
  • 38
    • 0028064764 scopus 로고
    • A revised European-American classification of lymphoid neoplasms: A proposal from the international lymphoma study group
    • Harris NL, Jaffe ES, Stein H et al (1994) A revised European-American classification of lymphoid neoplasms: a proposal from the international lymphoma study group. Blood 84 1361-1392
    • (1994) Blood , vol.84 , pp. 1361-1392
    • Harris, N.L.1    Jaffe, E.S.2    Stein, H.3
  • 39
    • 0024425887 scopus 로고
    • Checkpoint controls that ensure the order of cell cycle events
    • Hartwell LH and Weinert TA (1989) Checkpoint controls that ensure the order of cell cycle events. Science 246 629-634
    • (1989) Science , vol.246 , pp. 629-634
    • Hartwell, L.H.1    Weinert, T.A.2
  • 41
    • 0028061974 scopus 로고
    • CDK4 amplification is an alternative mechanism to p16 gene homozygous deletion in glioma cell lines
    • He J, Allen JR, Collins PV et al (1994) CDK4 amplification is an alternative mechanism to p16 gene homozygous deletion in glioma cell lines. Cancer Research 54 5804-5807
    • (1994) Cancer Research , vol.54 , pp. 5804-5807
    • He, J.1    Allen, J.R.2    Collins, P.V.3
  • 42
    • 0028315894 scopus 로고
    • Inducible regulatory elements in the human cyclin D1 promoter
    • Herber B, Truss M, Beato M and Müller R (1994) Inducible regulatory elements in the human cyclin D1 promoter. Oncogene 9 1295-1304
    • (1994) Oncogene , vol.9 , pp. 1295-1304
    • Herber, B.1    Truss, M.2    Beato, M.3    Müller, R.4
  • 43
    • 0028845142 scopus 로고
    • Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers
    • Herman JG, Merlo A, Mao L et al (1995) Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers. Cancer Research 55 4525-4530
    • (1995) Cancer Research , vol.55 , pp. 4525-4530
    • Herman, J.G.1    Merlo, A.2    Mao, L.3
  • 44
    • 0029134016 scopus 로고
    • Role of the cyclin-dependent kinase inhibitors in the development of cancer
    • Hirama T and Koeffler HP (1995) Role of the cyclin-dependent kinase inhibitors in the development of cancer. Blood 86 841-854
    • (1995) Blood , vol.86 , pp. 841-854
    • Hirama, T.1    Koeffler, H.P.2
  • 46
    • 0029031949 scopus 로고
    • The melanoma differentiation-associated gene mda-6, which encodes the cyclin-dependent kinase inhibitor p21, is differentially expressed during growth, differentiation and progression in human melanoma cells
    • Jiang H, Lin J, Su Z et al (1995) The melanoma differentiation-associated gene mda-6, which encodes the cyclin-dependent kinase inhibitor p21, is differentially expressed during growth, differentiation and progression in human melanoma cells. Oncogene 10 1855-1864
    • (1995) Oncogene , vol.10 , pp. 1855-1864
    • Jiang, H.1    Lin, J.2    Su, Z.3
  • 48
    • 0028121279 scopus 로고
    • A cell cycle regulator potentially involved in genesis of many tumor types
    • MH
    • Kamb A, Gruis NA, Weaver-Feldhaus J et al MH (1994) A cell cycle regulator potentially involved in genesis of many tumor types. Science 264 436-440
    • (1994) Science , vol.264 , pp. 436-440
    • Kamb, A.1    Gruis, N.A.2    Weaver-Feldhaus, J.3
  • 49
    • 0027288908 scopus 로고
    • Direct binding of cyclin D to the retinoblastoma gene product (pRb) and pRb phosphorylation by the cyclin D-dependent kinase CDK4
    • Kato J, Matsushime H, Hiebert SW, Ewen ME and Sherr CJ (1993) Direct binding of cyclin D to the retinoblastoma gene product (pRb) and pRb phosphorylation by the cyclin D-dependent kinase CDK4. Genes and Development 7 331-342
    • (1993) Genes and Development , vol.7 , pp. 331-342
    • Kato, J.1    Matsushime, H.2    Hiebert, S.W.3    Ewen, M.E.4    Sherr, C.J.5
  • 50
    • 0029007867 scopus 로고
    • Molecular analysis of the cyclin-dependent kinase inhibitor gene p27/Kip1 in human malignancies
    • Kawamata N, Morosetti R, Miller CW et al (1995) Molecular analysis of the cyclin-dependent kinase inhibitor gene p27/Kip1 in human malignancies. Cancer Research 55 2266-2269
    • (1995) Cancer Research , vol.55 , pp. 2266-2269
    • Kawamata, N.1    Morosetti, R.2    Miller, C.W.3
  • 55
    • 0029052951 scopus 로고
    • Tumour-derived p16 alleles encoding proteins defective in cell-cycle inhibition
    • Koh J, Enders GH, Dynlacht BD and Harlow E (1995) Tumour-derived p16 alleles encoding proteins defective in cell-cycle inhibition. Nature 375 506-510
    • (1995) Nature , vol.375 , pp. 506-510
    • Koh, J.1    Enders, G.H.2    Dynlacht, B.D.3    Harlow, E.4
  • 57
    • 0028981325 scopus 로고
    • Differentiation of P19 EC cells leads to differential modulation of cyclin-dependent kinase activities and to changes in the cell cycle profile
    • Kranenburg O, de Groot RP, Van der Eb AJ and Zantema A (1995) Differentiation of P19 EC cells leads to differential modulation of cyclin-dependent kinase activities and to changes in the cell cycle profile. Oncogene 10 87-95
    • (1995) Oncogene , vol.10 , pp. 87-95
    • Kranenburg, O.1    De Groot, R.P.2    Van Der Eb, A.J.3    Zantema, A.4
  • 58
    • 0026446824 scopus 로고
    • Proviral insertions near cyclin D1 in mouse lymphomas: A parallel for BCL1 translocations in human B-cell neoplasms
    • Lammie GA, Smith R, Silver J, Brookes S, Dickson C and Peters G (1992) Proviral insertions near cyclin D1 in mouse lymphomas: a parallel for BCL1 translocations in human B-cell neoplasms. Oncogene 7 2381-2387
    • (1992) Oncogene , vol.7 , pp. 2381-2387
    • Lammie, G.A.1    Smith, R.2    Silver, J.3    Brookes, S.4    Dickson, C.5    Peters, G.6
  • 59
    • 0027273790 scopus 로고
    • Amplification of cyclin genes in colorectal carcinomas
    • Leach FS, Elledge SJ, Sherr CJ et al (1993) Amplification of cyclin genes in colorectal carcinomas. Cancer Research 53 1986-1989
    • (1993) Cancer Research , vol.53 , pp. 1986-1989
    • Leach, F.S.1    Elledge, S.J.2    Sherr, C.J.3
  • 60
    • 0028988158 scopus 로고
    • KIP2, a cyclin-dependent kinase inhibitor with unique domain structure and tissue distribution
    • KIP2, a cyclin-dependent kinase inhibitor with unique domain structure and tissue distribution. Genes and Development 9 639-649
    • (1995) Genes and Development , vol.9 , pp. 639-649
    • Lee, M.-H.1    Reynisdottir, I.2    Massagué, J.3
  • 61
    • 0028845639 scopus 로고
    • Cyclin dependent kinase regulation
    • Lees E (1995) Cyclin dependent kinase regulation. Current Opinion in Cell Biology 7 773-780
    • (1995) Current Opinion in Cell Biology , vol.7 , pp. 773-780
    • Lees, E.1
  • 62
    • 0028881595 scopus 로고
    • Polymorphisms and probable lack of mutation in the WAF1-CIP1 gene in colorectal cancer
    • Li Y-J, Laurent-Puig P, Salmon RJ, Thomas G and Hamelin R (1995) Polymorphisms and probable lack of mutation in the WAF1-CIP1 gene in colorectal cancer. Oncogene 10 599-601
    • (1995) Oncogene , vol.10 , pp. 599-601
    • Li, Y.-J.1    Laurent-Puig, P.2    Salmon, R.J.3    Thomas, G.4    Hamelin, R.5
  • 63
    • 0027269711 scopus 로고
    • Deregulation of cyclins D1 and e and suppression of cdk2 and cdk4 in senescent human fibroblasts
    • Lucibello FC, Sewing A, Brüsselbach S, Bürger C and Müller R (1993) Deregulation of cyclins D1 and E and suppression of cdk2 and cdk4 in senescent human fibroblasts. Journal of Cell Science 105 123-133
    • (1993) Journal of Cell Science , vol.105 , pp. 123-133
    • Lucibello, F.C.1    Sewing, A.2    Brüsselbach, S.3    Bürger, C.4    Müller, R.5
  • 64
    • 0028279059 scopus 로고
    • DNA tumor virus oncoproteins and retinoblastoma gene mutations share the ability to relieve the cell's requirement for cyclin D1 function in G1
    • Lukas J, Müller H, Spitkovsky D et al (1994a) DNA tumor virus oncoproteins and retinoblastoma gene mutations share the ability to relieve the cell's requirement for cyclin D1 function in G1. Journal of Cell Biology 125 625-638
    • (1994) Journal of Cell Biology , vol.125 , pp. 625-638
    • Lukas, J.1    Müller, H.2    Spitkovsky, D.3
  • 65
    • 0027958344 scopus 로고
    • Cyclin D1 protein oscillates and is essential for cell cycle progression in human tumour cell lines
    • Lukas J, Pagano M, Staskova Z, Draetta G and Bartek J (1994b) Cyclin D1 protein oscillates and is essential for cell cycle progression in human tumour cell lines. Oncogene 9 707-718
    • (1994) Oncogene , vol.9 , pp. 707-718
    • Lukas, J.1    Pagano, M.2    Staskova, Z.3    Draetta, G.4    Bartek, J.5
  • 67
    • 0028999777 scopus 로고
    • Cyclin D2 is a moderately oscillating nucleoprotein required for G1 phase progression in specific cell types
    • Lukas J, Bartkova J, Welcker M et al (1995b) Cyclin D2 is a moderately oscillating nucleoprotein required for G1 phase progression in specific cell types. Oncogene 10 2125-2134
    • (1995) Oncogene , vol.10 , pp. 2125-2134
    • Lukas, J.1    Bartkova, J.2    Welcker, M.3
  • 68
    • 0029054399 scopus 로고
    • Retinoblastoma-protein-dependent cell cycle inhibition by the tumour suppressor p16
    • Lukas J, Parry D, Aagaard L et al (1995c) Retinoblastoma-protein-dependent cell cycle inhibition by the tumour suppressor p16. Nature 375 503-506
    • (1995) Nature , vol.375 , pp. 503-506
    • Lukas, J.1    Parry, D.2    Aagaard, L.3
  • 70
    • 0028963841 scopus 로고
    • p53-dependent and independent expression of p21 during cell growth, differentiation, and DNA damage
    • Macleod KF, Sherry N, Hannon G et al (1995) p53-dependent and independent expression of p21 during cell growth, differentiation, and DNA damage. Genes and Development 9 935-944
    • (1995) Genes and Development , vol.9 , pp. 935-944
    • Macleod, K.F.1    Sherry, N.2    Hannon, G.3
  • 71
    • 0029118134 scopus 로고
    • Homozygous deletion frequency and expression levels of the CDKN2 gene in human sarcomas-relationship to amplification and mRNA levels of CDK4 and CCND1
    • Maelandsmo GM, Berner J-M, Flørenes VA et al (1995) Homozygous deletion frequency and expression levels of the CDKN2 gene in human sarcomas-relationship to amplification and mRNA levels of CDK4 and CCND1. British Journal of Cancer 72 393-398
    • (1995) British Journal of Cancer , vol.72 , pp. 393-398
    • Maelandsmo, G.M.1    Berner, J.-M.2    Flørenes, V.A.3
  • 72
    • 0028070707 scopus 로고
    • A challenge to the p16 gene as a major tumor suppressor
    • Marx J (1994) A challenge to the p16 gene as a major tumor suppressor. Science 264 1846
    • (1994) Science , vol.264 , pp. 1846
    • Marx, J.1
  • 74
    • 0025819962 scopus 로고
    • Colony-stimulating factor I regulates novel cyclins during the G1 phase of the cell cycle
    • Matsushime H, Roussel MF, Ashmun RA and Sherr CJ (1991) Colony-stimulating factor I regulates novel cyclins during the G1 phase of the cell cycle. Cell 65 701-713
    • (1991) Cell , vol.65 , pp. 701-713
    • Matsushime, H.1    Roussel, M.F.2    Ashmun, R.A.3    Sherr, C.J.4
  • 77
    • 0029011539 scopus 로고
    • 5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers
    • Merlo A, Herman JG, Mao L et al (1995) 5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers. Nature Medicine 1 686-692
    • (1995) Nature Medicine , vol.1 , pp. 686-692
    • Merlo, A.1    Herman, J.G.2    Mao, L.3
  • 79
    • 0028931265 scopus 로고
    • Principles of CDK regulation
    • Morgan DO (1995) Principles of CDK regulation. Nature 374 131-134
    • (1995) Nature , vol.374 , pp. 131-134
    • Morgan, D.O.1
  • 81
    • 0025806904 scopus 로고
    • A novel cyclin encoded by a bcl 1-linked candidate oncogene
    • Motokura T, Bloom T, Kim HG et al (1991) A novel cyclin encoded by a bcl 1-linked candidate oncogene. Nature 350 512-515
    • (1991) Nature , vol.350 , pp. 512-515
    • Motokura, T.1    Bloom, T.2    Kim, H.G.3
  • 83
    • 0028275733 scopus 로고
    • Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers
    • Nobori T, Miura K, Wu DJ, Lois A, Takabayashi K and Carson DA (1994) Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers. Nature 368 753-756
    • (1994) Nature , vol.368 , pp. 753-756
    • Nobori, T.1    Miura, K.2    Wu, D.J.3    Lois, A.4    Takabayashi, K.5    Carson, D.A.6
  • 90
    • 0028129498 scopus 로고
    • Cyclin D1-mediated inhibition of repair and replicative DNA synthesis in human fibroblasts
    • Pagano M, Theodoras AM, Tarn SW and Draetta GF (1994) Cyclin D1-mediated inhibition of repair and replicative DNA synthesis in human fibroblasts. Genes and Development 8 1627-1639
    • (1994) Genes and Development , vol.8 , pp. 1627-1639
    • Pagano, M.1    Theodoras, A.M.2    Tarn, S.W.3    Draetta, G.F.4
  • 91
    • 0024473604 scopus 로고
    • G-1 events and regulation of cell proliferation
    • Pardee AB (1989) G-1 events and regulation of cell proliferation. Science 246 603-608
    • (1989) Science , vol.246 , pp. 603-608
    • Pardee, A.B.1
  • 95
    • 0030025518 scopus 로고    scopus 로고
    • Compilation of somatic mutations of the CDKN2 gene in human cancers: Non-random distribution of base substitutions
    • Pollock PM, Pearson JV and Hayward NK (1996) Compilation of somatic mutations of the CDKN2 gene in human cancers: non-random distribution of base substitutions. Genes Chromosomes and Cancer 15 77-88
    • (1996) Genes Chromosomes and Cancer , vol.15 , pp. 77-88
    • Pollock, P.M.1    Pearson, J.V.2    Hayward, N.K.3
  • 96
    • 0028176483 scopus 로고
    • KiP1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals
    • KiP1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals. Cell 78 59-66
    • (1994) Cell , vol.78 , pp. 59-66
    • Polyak, K.1    Lee, M.-H.2    Erdjument-Bromage, H.3
  • 97
    • 0028986932 scopus 로고
    • Kip1: Chromosomal mapping to 12p12-12p13.1 and absence of mutations in human tumors
    • Kip1: chromosomal mapping to 12p12-12p13.1 and absence of mutations in human tumors. Cancer Research 55 1211-1214
    • (1995) Cancer Research , vol.55 , pp. 1211-1214
    • Ponce-Castañeda, M.V.1    Lee, M.-H.2    Latres, E.3
  • 100
    • 0027978368 scopus 로고
    • Amplification of multiple genes from chromosomal region 12q13-14 in human malignant gliomas: Preliminary mapping of the amplicons shows preferential involvement of CDK4, SAS, and MDM2
    • J R
    • Reifenberger G, J R, Ichimura K, Meltzer PS and Collins VP (1994) Amplification of multiple genes from chromosomal region 12q13-14 in human malignant gliomas: preliminary mapping of the amplicons shows preferential involvement of CDK4, SAS, and MDM2. Cancer Research 54 4299-4303
    • (1994) Cancer Research , vol.54 , pp. 4299-4303
    • Reifenberger, G.1    Ichimura, K.2    Meltzer, P.S.3    Collins, V.P.4
  • 103
    • 0027365517 scopus 로고
    • Elevated levels of cyclin D1 protein in response to increased expression of eukaryotic initiation factor 4E
    • Rosenwald IB, Lazaris-Karatzas A, Sonenberg N and Schmidt EV (1993) Elevated levels of cyclin D1 protein in response to increased expression of eukaryotic initiation factor 4E. Molecular and Cellular Biology 13 7358-7363
    • (1993) Molecular and Cellular Biology , vol.13 , pp. 7358-7363
    • Rosenwald, I.B.1    Lazaris-Karatzas, A.2    Sonenberg, N.3    Schmidt, E.V.4
  • 105
    • 0027769876 scopus 로고
    • A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4
    • Serrano M, Hannon GJ and Beach D (1993) A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4. Nature 366 704-707
    • (1993) Nature , vol.366 , pp. 704-707
    • Serrano, M.1    Hannon, G.J.2    Beach, D.3
  • 106
    • 0027416338 scopus 로고
    • Human cyclin D1 encodes a labile nuclear protein whose synthesis is directly induced by growth factors and suppressed by cyclic AMP
    • Sewing A, Bürger C, Brüsselbach S, Schalk C, Lucibello FC and Müller R (1993) Human cyclin D1 encodes a labile nuclear protein whose synthesis is directly induced by growth factors and suppressed by cyclic AMP. Journal of Cell Science 104 545-554
    • (1993) Journal of Cell Science , vol.104 , pp. 545-554
    • Sewing, A.1    Bürger, C.2    Brüsselbach, S.3    Schalk, C.4    Lucibello, F.C.5    Müller, R.6
  • 108
    • 0028988585 scopus 로고
    • Inhibitors of mammalian G1 cyclin-dependent kinases
    • Sherr CJ and Roberts JM (1995) Inhibitors of mammalian G1 cyclin-dependent kinases. Genes and Development 9 1149-1163
    • (1995) Genes and Development , vol.9 , pp. 1149-1163
    • Sherr, C.J.1    Roberts, J.M.2
  • 109
    • 0027940495 scopus 로고
    • Absence of WAF1 mutations in a variety of human malignancies
    • Shiohara M, El-Deiry WS, Wada M et al (1994) Absence of WAF1 mutations in a variety of human malignancies. Blood 84 3781-3784
    • (1994) Blood , vol.84 , pp. 3781-3784
    • Shiohara, M.1    El-Deiry, W.S.2    Wada, M.3
  • 110
    • 0028233417 scopus 로고
    • 1 transition during immortalization of resting human B lymphocytes by Epstein-Barr virus
    • 1 transition during immortalization of resting human B lymphocytes by Epstein-Barr virus. EMBO Journal 13 3321-3328
    • (1994) EMBO Journal , vol.13 , pp. 3321-3328
    • Sinclair, A.J.1    Palmero, I.2    Peters, G.3    Farrell, P.J.4
  • 111
    • 0028360766 scopus 로고
    • Overexpression of E2F-1 in rat embryo fibroblasts leads to neoplastic transformation
    • Singh P, Wong SH and Hong W (1994) Overexpression of E2F-1 in rat embryo fibroblasts leads to neoplastic transformation. EMBO Journal 13 3329-3338
    • (1994) EMBO Journal , vol.13 , pp. 3329-3338
    • Singh, P.1    Wong, S.H.2    Hong, W.3
  • 112
    • 0029927496 scopus 로고    scopus 로고
    • Mutational analysis of the candidate tumor suppressor genes TEL and KIP1 in childhood acute lymphoblastic leukemia
    • Stegmaier K, Takeuchi S, Golub TR et al (1996) Mutational analysis of the candidate tumor suppressor genes TEL and KIP1 in childhood acute lymphoblastic leukemia. Cancer Research 56 1413-1417
    • (1996) Cancer Research , vol.56 , pp. 1413-1417
    • Stegmaier, K.1    Takeuchi, S.2    Golub, T.R.3
  • 113
    • 0028518750 scopus 로고
    • Cipl blocks the initiation of DNA replication in Xenopus extracts by inhibition of cyclin-dependent kinases
    • Strausfeld UP, Howell M, Rempel R, Mailer JL, Hunt T and Blow JJ (1994) Cipl blocks the initiation of DNA replication in Xenopus extracts by inhibition of cyclin-dependent kinases. Current Biology 4 876-883
    • (1994) Current Biology , vol.4 , pp. 876-883
    • Strausfeld, U.P.1    Howell, M.2    Rempel, R.3    Mailer, J.L.4    Hunt, T.5    Blow, J.J.6
  • 114
    • 0028910392 scopus 로고
    • ser-arg polymorphism of the WAF-1/CIP-1/p21 tumor suppressor gene in nasopharyngeal carcinoma (NPC): The polymorphism distinguishes Caucasians from Chinese
    • ser-arg polymorphism of the WAF-1/CIP-1/p21 tumor suppressor gene in nasopharyngeal carcinoma (NPC): the polymorphism distinguishes Caucasians from Chinese. Cancer Epidemiology, Biomarkers and Prevention 4 261-267
    • (1995) Cancer Epidemiology, Biomarkers and Prevention , vol.4 , pp. 261-267
    • Sun, Y.1    Hildesheim, A.2    Li, H.3
  • 115
    • 0028946009 scopus 로고
    • sdi1/cip1/waf1 with increasing division age in both normal and SV40-transformed human fibroblasts
    • sdi1/cip1/waf1 with increasing division age in both normal and SV40-transformed human fibroblasts. Oncogene 10 835-840
    • (1995) Oncogene , vol.10 , pp. 835-840
    • Tahara, H.1    Sato, E.2    Noda, A.3    Ide, T.4
  • 116
    • 0028363519 scopus 로고
    • p27, a novel inhibitor of G1 cyclin-cdk protein kinase activity, is related to p21
    • Toyoshima H and Hunter T (1994) p27, a novel inhibitor of G1 cyclin-cdk protein kinase activity, is related to p21. Cell 78 67-74
    • (1994) Cell , vol.78 , pp. 67-74
    • Toyoshima, H.1    Hunter, T.2
  • 117
    • 0028352434 scopus 로고
    • The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA
    • Waga S, Hannon GJ, Beach D and Stillman B (1994) The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA. Nature 369 574-578
    • (1994) Nature , vol.369 , pp. 574-578
    • Waga, S.1    Hannon, G.J.2    Beach, D.3    Stillman, B.4
  • 120
    • 0029033861 scopus 로고
    • The retinoblastoma protein and cell cycle control
    • Weinberg RA (1995) The retinoblastoma protein and cell cycle control. Cell 81 323-330
    • (1995) Cell , vol.81 , pp. 323-330
    • Weinberg, R.A.1
  • 122
    • 0027146274 scopus 로고
    • Growth factor regulation of cyclin D1 mRNA expression through protein synthesis-dependent and independent mechanisms
    • Winston JT and Pledger WJ (1993) Growth factor regulation of cyclin D1 mRNA expression through protein synthesis-dependent and independent mechanisms. Molecular Biology of the Cell 4 1133-1144
    • (1993) Molecular Biology of the Cell , vol.4 , pp. 1133-1144
    • Winston, J.T.1    Pledger, W.J.2
  • 124
    • 0028978274 scopus 로고
    • Ink4a-insensitive CDK4 mutant targeted by cytolytic T lymphocytes in a human melanoma
    • Ink4a-insensitive CDK4 mutant targeted by cytolytic T lymphocytes in a human melanoma. Science 269 1281-1284
    • (1995) Science , vol.269 , pp. 1281-1284
    • Wölfel, T.1    Hauer, M.2    Schneider, J.3
  • 128
    • 0028985518 scopus 로고
    • p53-independent induction of WAF1/CIP1 in human leukemia cells is correlated with growth arrest accompanying monocyte/macrophage differentiation
    • Zhang W, Grasso L, McClain CD et al (1995) p53-independent induction of WAF1/CIP1 in human leukemia cells is correlated with growth arrest accompanying monocyte/macrophage differentiation. Cancer Research 55 668-674
    • (1995) Cancer Research , vol.55 , pp. 668-674
    • Zhang, W.1    Grasso, L.2    McClain, C.D.3
  • 129
    • 0029664339 scopus 로고    scopus 로고
    • INK4a binding domain of CDK4 in familial melanoma
    • INK4a binding domain of CDK4 in familial melanoma. Nature Genetics 12 97-99
    • (1996) Nature Genetics , vol.12 , pp. 97-99
    • Zuo, L.1    Weger, J.2    Yang, Q.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.