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Volumn 43, Issue 4, 2005, Pages 704-710

Interleukin-6 plays a crucial role in the hepatic expression of SOCS3 during acute inflammatory processes in vivo

Author keywords

IL 6 knockkout mice; Inflammation; Interleukin 6; Liver; LPS; SOCS3; Turpentine

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; INTERLEUKIN 6; MESSENGER RNA; SUPPRESSOR OF CYTOKINE SIGNALING 3; TUMOR NECROSIS FACTOR RECEPTOR 1; TURPENTINE;

EID: 24344480077     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2005.02.048     Document Type: Article
Times cited : (37)

References (48)
  • 1
    • 0028095919 scopus 로고
    • The acute phase response
    • H. Baumann, and J. Gauldie The acute phase response Immunol Today 15 1994 74 80
    • (1994) Immunol Today , vol.15 , pp. 74-80
    • Baumann, H.1    Gauldie, J.2
  • 2
    • 0030589152 scopus 로고    scopus 로고
    • Initiation of acute phase response and synthesis of cytokines
    • A. Koj Initiation of acute phase response and synthesis of cytokines Biochim Biophys Acta 1317 1996 84 94
    • (1996) Biochim Biophys Acta , vol.1317 , pp. 84-94
    • Koj, A.1
  • 3
    • 0033545342 scopus 로고    scopus 로고
    • Acute-phase proteins and other systemic responses to inflammation
    • C. Gabay, and I. Kushner Acute-phase proteins and other systemic responses to inflammation N Engl J Med 340 1999 448 454
    • (1999) N Engl J Med , vol.340 , pp. 448-454
    • Gabay, C.1    Kushner, I.2
  • 5
    • 0034887798 scopus 로고    scopus 로고
    • Gene transcription in hepatocytes during the acute phase of a systemic inflammation: From transcription factors to target genes
    • P. Ruminy, C. Gangneux, S. Claeyssens, M. Scotte, M. Daveau, and J.P. Salier Gene transcription in hepatocytes during the acute phase of a systemic inflammation: from transcription factors to target genes Inflamm Res 50 2001 383 390
    • (2001) Inflamm Res , vol.50 , pp. 383-390
    • Ruminy, P.1    Gangneux, C.2    Claeyssens, S.3    Scotte, M.4    Daveau, M.5    Salier, J.P.6
  • 6
    • 0025190892 scopus 로고
    • Interleukin-6 and the acute phase response
    • P.C. Heinrich, J.V. Castell, and T. Andus Interleukin-6 and the acute phase response Biochem J 265 1990 621 636
    • (1990) Biochem J , vol.265 , pp. 621-636
    • Heinrich, P.C.1    Castell, J.V.2    Andus, T.3
  • 8
    • 0024581491 scopus 로고
    • Interleukin-6 is the major regulator of acute phase protein synthesis in adult human hepatocytes
    • J.V. Castell, M.J. Gomez-Lechon, M. David, T. Andus, T. Geiger, and R. Trullenque Interleukin-6 is the major regulator of acute phase protein synthesis in adult human hepatocytes FEBS Lett 242 1989 237 239
    • (1989) FEBS Lett , vol.242 , pp. 237-239
    • Castell, J.V.1    Gomez-Lechon, M.J.2    David, M.3    Andus, T.4    Geiger, T.5    Trullenque, R.6
  • 10
    • 0031028140 scopus 로고    scopus 로고
    • Initiation of liver growth by tumor necrosis factor: Deficient liver regeneration in mice lacking type I tumor necrosis factor receptor
    • Y. Yamada, I. Kirillova, J.J. Peschon, and N. Fausto Initiation of liver growth by tumor necrosis factor: deficient liver regeneration in mice lacking type I tumor necrosis factor receptor Proc Natl Acad Sci USA 94 1997 1441 1446
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 1441-1446
    • Yamada, Y.1    Kirillova, I.2    Peschon, J.J.3    Fausto, N.4
  • 11
    • 0031780066 scopus 로고    scopus 로고
    • Deficient liver regeneration after carbon tetrachloride injury in mice lacking type 1 but not type 2 tumor necrosis factor receptor
    • Y. Yamada, and N. Fausto Deficient liver regeneration after carbon tetrachloride injury in mice lacking type 1 but not type 2 tumor necrosis factor receptor Am J Pathol 152 1998 1577 1589
    • (1998) Am J Pathol , vol.152 , pp. 1577-1589
    • Yamada, Y.1    Fausto, N.2
  • 12
    • 0033970969 scopus 로고    scopus 로고
    • Increased toxin-induced liver injury and fibrosis in interleukin-6- deficient mice
    • K. Kovalovich, R.A. DeAngelis, W. Li, E.E. Furth, G. Ciliberto, and R. Taub Increased toxin-induced liver injury and fibrosis in interleukin-6- deficient mice Hepatology 31 2000 149 159
    • (2000) Hepatology , vol.31 , pp. 149-159
    • Kovalovich, K.1    Deangelis, R.A.2    Li, W.3    Furth, E.E.4    Ciliberto, G.5    Taub, R.6
  • 13
    • 0242407711 scopus 로고    scopus 로고
    • Negative regulation of cytokine signaling influences inflammation
    • A. Yoshimura, H. Mori, M. Ohishi, D. Aki, and T. Hanada Negative regulation of cytokine signaling influences inflammation Curr Opin Immunol 15 2003 704 708
    • (2003) Curr Opin Immunol , vol.15 , pp. 704-708
    • Yoshimura, A.1    Mori, H.2    Ohishi, M.3    Aki, D.4    Hanada, T.5
  • 14
    • 0030762368 scopus 로고    scopus 로고
    • Accelerated development of liver fibrosis in CCl4-treated rats by the weekly induction of acute phase response episodes: Upregulation of alpha1(I) procollagen and tissue inhibitor of metalloproteinase-1 mRNAs
    • P. Greenwel, and M. Rojkind Accelerated development of liver fibrosis in CCl4-treated rats by the weekly induction of acute phase response episodes: upregulation of alpha1(I) procollagen and tissue inhibitor of metalloproteinase-1 mRNAs Biochim Biophys Acta 1361 1997 177 184
    • (1997) Biochim Biophys Acta , vol.1361 , pp. 177-184
    • Greenwel, P.1    Rojkind, M.2
  • 15
    • 0032168152 scopus 로고    scopus 로고
    • Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway
    • P.C. Heinrich, I. Behrmann, G. Müller-Newen, F. Schaper, and L. Graeve Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway Biochem J 334 1998 297 314
    • (1998) Biochem J , vol.334 , pp. 297-314
    • Heinrich, P.C.1    Behrmann, I.2    Müller-Newen, G.3    Schaper, F.4    Graeve, L.5
  • 17
    • 0033233214 scopus 로고    scopus 로고
    • LPS and TNFalpha induce SOCS3 mRNA and inhibit IL-6-induced activation of STAT3 in macrophages
    • J.G. Bode, A. Nimmesgern, J. Schmitz, F. Schaper, M. Schmitt, and W. Frisch LPS and TNFalpha induce SOCS3 mRNA and inhibit IL-6-induced activation of STAT3 in macrophages FEBS Lett 463 1999 365 370
    • (1999) FEBS Lett , vol.463 , pp. 365-370
    • Bode, J.G.1    Nimmesgern, A.2    Schmitz, J.3    Schaper, F.4    Schmitt, M.5    Frisch, W.6
  • 18
    • 0033197958 scopus 로고    scopus 로고
    • Lipopolysaccharide induces in macrophages the synthesis of the suppressor of cytokine signaling 3 and suppresses signal transduction in response to the activating factor IFN-gamma
    • D. Stoiber, P. Kovarik, S. Cohney, J.A. Johnston, P. Steinlein, and T. Decker Lipopolysaccharide induces in macrophages the synthesis of the suppressor of cytokine signaling 3 and suppresses signal transduction in response to the activating factor IFN-gamma J Immunol 163 1999 2640 2647
    • (1999) J Immunol , vol.163 , pp. 2640-2647
    • Stoiber, D.1    Kovarik, P.2    Cohney, S.3    Johnston, J.A.4    Steinlein, P.5    Decker, T.6
  • 19
    • 0035877256 scopus 로고    scopus 로고
    • Suppressors of cytokine signaling (SOCS)-1 and SOCS-3 are induced by CpG-DNA and modulate cytokine responses in APCs
    • A.H. Dalpke, S. Opper, S. Zimmermann, and K. Heeg Suppressors of cytokine signaling (SOCS)-1 and SOCS-3 are induced by CpG-DNA and modulate cytokine responses in APCs J Immunol 166 2001 7082 7089
    • (2001) J Immunol , vol.166 , pp. 7082-7089
    • Dalpke, A.H.1    Opper, S.2    Zimmermann, S.3    Heeg, K.4
  • 20
    • 0028328436 scopus 로고
    • Impaired immune and acute-phase responses in interleukin-6-deficient mice
    • M. Kopf, H. Baumann, G. Freer, M. Freudenberg, M. Lamers, and T. Kishimoto Impaired immune and acute-phase responses in interleukin-6-deficient mice Nature 368 1994 339 342
    • (1994) Nature , vol.368 , pp. 339-342
    • Kopf, M.1    Baumann, H.2    Freer, G.3    Freudenberg, M.4    Lamers, M.5    Kishimoto, T.6
  • 21
    • 0001421104 scopus 로고    scopus 로고
    • Different protein turnover of interleukin-6-type cytokine signalling components
    • E. Siewert, W. Müller-Esterl, R. Starr, P.C. Heinrich, and F. Schaper Different protein turnover of interleukin-6-type cytokine signalling components Eur J Biochem 265 1999 251 257
    • (1999) Eur J Biochem , vol.265 , pp. 251-257
    • Siewert, E.1    Müller-Esterl, W.2    Starr, R.3    Heinrich, P.C.4    Schaper, F.5
  • 22
    • 0036595049 scopus 로고    scopus 로고
    • Suppressors of cytokine signalling (SOCS) in the immune system
    • W.S. Alexander Suppressors of cytokine signalling (SOCS) in the immune system Nat Rev Immunol 2 2002 410 416
    • (2002) Nat Rev Immunol , vol.2 , pp. 410-416
    • Alexander, W.S.1
  • 23
    • 0344440953 scopus 로고    scopus 로고
    • Regulation of cytokine signaling by SOCS family molecules
    • M. Fujimoto, and T. Naka Regulation of cytokine signaling by SOCS family molecules Trends Immunol 24 2003 659 666
    • (2003) Trends Immunol , vol.24 , pp. 659-666
    • Fujimoto, M.1    Naka, T.2
  • 24
    • 0036892964 scopus 로고    scopus 로고
    • Suppressors of cytokine signaling: Relevance to gastrointestinal function and disease
    • C.J. Greenhalgh, M.E. Miller, D.J. Hilton, and P.K. Lund Suppressors of cytokine signaling: Relevance to gastrointestinal function and disease Gastroenterology 123 2002 2064 2081
    • (2002) Gastroenterology , vol.123 , pp. 2064-2081
    • Greenhalgh, C.J.1    Miller, M.E.2    Hilton, D.J.3    Lund, P.K.4
  • 26
    • 0035006109 scopus 로고    scopus 로고
    • Tyrosine-phosphorylated SOCS-3 inhibits STAT activation but binds to p120 RasGAP and activates Ras
    • N.A. Cacalano, D. Sanden, and J.A. Johnston Tyrosine-phosphorylated SOCS-3 inhibits STAT activation but binds to p120 RasGAP and activates Ras Nat Cell Biol 3 2001 460 465
    • (2001) Nat Cell Biol , vol.3 , pp. 460-465
    • Cacalano, N.A.1    Sanden, D.2    Johnston, J.A.3
  • 27
    • 0037443661 scopus 로고    scopus 로고
    • Activation of STAT3 by IL-6 and IL-10 in primary human macrophages is differentially modulated by suppressor of cytokine signaling 3
    • C. Niemand, A. Nimmesgern, S. Haan, P. Fischer, F. Schaper, and R. Rossaint Activation of STAT3 by IL-6 and IL-10 in primary human macrophages is differentially modulated by suppressor of cytokine signaling 3 J Immunol 170 2003 3263 3272
    • (2003) J Immunol , vol.170 , pp. 3263-3272
    • Niemand, C.1    Nimmesgern, A.2    Haan, S.3    Fischer, P.4    Schaper, F.5    Rossaint, R.6
  • 28
    • 0037600741 scopus 로고    scopus 로고
    • IL-6 induces an anti-inflammatory response in the absence of SOCS3 in macrophages
    • H. Yasukawa, M. Ohishi, H. Mori, M. Murakami, T. Chinen, and D. Aki IL-6 induces an anti-inflammatory response in the absence of SOCS3 in macrophages Nat Immunol 4 2003 551 556
    • (2003) Nat Immunol , vol.4 , pp. 551-556
    • Yasukawa, H.1    Ohishi, M.2    Mori, H.3    Murakami, M.4    Chinen, T.5    Aki, D.6
  • 29
    • 0036084675 scopus 로고    scopus 로고
    • Invited review: Cytokine regulation of fever: Studies using gene knockout mice
    • L.R. Leon Invited review: cytokine regulation of fever: studies using gene knockout mice J Appl Physiol 92 2002 2648 2655
    • (2002) J Appl Physiol , vol.92 , pp. 2648-2655
    • Leon, L.R.1
  • 31
    • 0034234716 scopus 로고    scopus 로고
    • Hepatic cytochrome P450 down-regulation during aseptic inflammation in the mouse is interleukin 6 dependent
    • E. Siewert, R. Bort, R. Kluge, P.C. Heinrich, J. Castell, and R. Jover Hepatic cytochrome P450 down-regulation during aseptic inflammation in the mouse is interleukin 6 dependent Hepatology 32 2000 49 55
    • (2000) Hepatology , vol.32 , pp. 49-55
    • Siewert, E.1    Bort, R.2    Kluge, R.3    Heinrich, P.C.4    Castell, J.5    Jover, R.6
  • 32
    • 0042970542 scopus 로고    scopus 로고
    • Triggering of Toll-like receptors modulates IFN-gamma signaling: Involvement of serine 727 STAT1 phosphorylation and suppressors of cytokine signaling
    • A.H. Dalpke, S. Eckerle, M. Frey, and K. Heeg Triggering of Toll-like receptors modulates IFN-gamma signaling: involvement of serine 727 STAT1 phosphorylation and suppressors of cytokine signaling Eur J Immunol 33 2003 1776 1787
    • (2003) Eur J Immunol , vol.33 , pp. 1776-1787
    • Dalpke, A.H.1    Eckerle, S.2    Frey, M.3    Heeg, K.4
  • 33
    • 0029873663 scopus 로고    scopus 로고
    • Differential expression of cytokine genes in monocytes, peritoneal macrophages and liver following endotoxin- or turpentine-induced inflammation in rat
    • M. Scotté, M. Hiron, S. Masson, S. Lyoumi, F. Banine, and P. Teniere Differential expression of cytokine genes in monocytes, peritoneal macrophages and liver following endotoxin- or turpentine-induced inflammation in rat Cytokine 8 1996 115 120
    • (1996) Cytokine , vol.8 , pp. 115-120
    • Scotté, M.1    Hiron, M.2    Masson, S.3    Lyoumi, S.4    Banine, F.5    Teniere, P.6
  • 34
    • 0346157324 scopus 로고    scopus 로고
    • Acquiring signalling specificity from the cytokine receptor gp130
    • M. Ernst, and B.J. Jenkins Acquiring signalling specificity from the cytokine receptor gp130 Trends Genet 20 2004 23 32
    • (2004) Trends Genet , vol.20 , pp. 23-32
    • Ernst, M.1    Jenkins, B.J.2
  • 35
    • 0030013088 scopus 로고    scopus 로고
    • The inflammatory response in interleukin-1 beta-deficient mice: Comparison with other cytokine-related knock-out mice
    • G. Fantuzzi, and C.A. Dinarello The inflammatory response in interleukin-1 beta-deficient mice: comparison with other cytokine-related knock-out mice J Leukoc Biol 59 1996 489 493
    • (1996) J Leukoc Biol , vol.59 , pp. 489-493
    • Fantuzzi, G.1    Dinarello, C.A.2
  • 36
    • 0027417956 scopus 로고
    • Regulation of IL-6 and the hepatic IL-6 receptor in acute inflammation in vivo
    • M. Geisterfer, C. Richards, M. Baumann, G. Fey, D. Gywnne, and J. Gauldie Regulation of IL-6 and the hepatic IL-6 receptor in acute inflammation in vivo Cytokine 5 1993 1 7
    • (1993) Cytokine , vol.5 , pp. 1-7
    • Geisterfer, M.1    Richards, C.2    Baumann, M.3    Fey, G.4    Gywnne, D.5    Gauldie, J.6
  • 37
    • 0029157723 scopus 로고
    • Resistance to fever induction and impaired acute-phase response in interleukin-1 beta-deficient mice
    • H. Zheng, D. Fletcher, W. Kozak, M. Jiang, K.J. Hofmann, and C.A. Conn Resistance to fever induction and impaired acute-phase response in interleukin-1 beta-deficient mice Immunity 3 1995 9 19
    • (1995) Immunity , vol.3 , pp. 9-19
    • Zheng, H.1    Fletcher, D.2    Kozak, W.3    Jiang, M.4    Hofmann, K.J.5    Conn, C.A.6
  • 38
    • 0034635550 scopus 로고    scopus 로고
    • Role of the suppressor of cytokine signaling-3 in mediating the inhibitory effects of interleukin-1beta on the growth hormone-dependent transcription of the acid-labile subunit gene in liver cells
    • Y.R. Boisclair, J. Wang, J. Shi, K.R. Hurst, and G.T. Ooi Role of the suppressor of cytokine signaling-3 in mediating the inhibitory effects of interleukin-1beta on the growth hormone-dependent transcription of the acid-labile subunit gene in liver cells J Biol Chem 275 2000 3841 3847
    • (2000) J Biol Chem , vol.275 , pp. 3841-3847
    • Boisclair, Y.R.1    Wang, J.2    Shi, J.3    Hurst, K.R.4    Ooi, G.T.5
  • 39
    • 0027297663 scopus 로고
    • Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection
    • K. Pfeffer, T. Matsuyama, T.M. Kundig, A. Wakeham, K. Kishihara, and A. Shahinian Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection Cell 73 1993 457 467
    • (1993) Cell , vol.73 , pp. 457-467
    • Pfeffer, K.1    Matsuyama, T.2    Kundig, T.M.3    Wakeham, A.4    Kishihara, K.5    Shahinian, A.6
  • 40
    • 0028169248 scopus 로고
    • Tumor necrosis factor-alpha regulates in vivo nitric oxide synthesis and induces liver injury during endotoxemia
    • B.G. Harbrecht, M. Di Silvio, A.J. Demetris, R.L. Simmons, and T.R. Billiar Tumor necrosis factor-alpha regulates in vivo nitric oxide synthesis and induces liver injury during endotoxemia Hepatology 20 1994 1055 1060
    • (1994) Hepatology , vol.20 , pp. 1055-1060
    • Harbrecht, B.G.1    Di Silvio, M.2    Demetris, A.J.3    Simmons, R.L.4    Billiar, T.R.5
  • 42
    • 0035409338 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha attenuates interferon alpha signaling in the liver: Involvement of SOCS3 and SHP2 and implication in resistance to interferon therapy
    • F. Hong, V.A. Nguyen, and B. Gao Tumor necrosis factor alpha attenuates interferon alpha signaling in the liver: involvement of SOCS3 and SHP2 and implication in resistance to interferon therapy FASEB J 15 2001 1595 1597
    • (2001) FASEB J , vol.15 , pp. 1595-1597
    • Hong, F.1    Nguyen, V.A.2    Gao, B.3
  • 43
    • 0037784230 scopus 로고    scopus 로고
    • Interleukin 6/gp130-dependent pathways are protective during chronic liver diseases
    • K.L. Streetz, F. Tacke, L. Leifeld, T. Wustefeld, A. Graw, and C. Klein Interleukin 6/gp130-dependent pathways are protective during chronic liver diseases Hepatology 38 2003 218 229
    • (2003) Hepatology , vol.38 , pp. 218-229
    • Streetz, K.L.1    Tacke, F.2    Leifeld, L.3    Wustefeld, T.4    Graw, A.5    Klein, C.6
  • 44
    • 0346121599 scopus 로고    scopus 로고
    • Suppressors of cytokine signaling and immunity
    • M. Kubo, T. Hanada, and A. Yoshimura Suppressors of cytokine signaling and immunity Nat Immunol 4 2003 1169 1176
    • (2003) Nat Immunol , vol.4 , pp. 1169-1176
    • Kubo, M.1    Hanada, T.2    Yoshimura, A.3
  • 45
    • 0031858640 scopus 로고    scopus 로고
    • Hepatocellular hyperplasia, plasmacytoma formation, and extramedullary hematopoiesis in interleukin (IL)-6/soluble IL-6 receptor double-transgenic mice
    • P. Schirmacher, M. Peters, G. Ciliberto, M. Blessing, J. Lotz, and K.H. Meyer zum Buschenfelde Hepatocellular hyperplasia, plasmacytoma formation, and extramedullary hematopoiesis in interleukin (IL)-6/soluble IL-6 receptor double-transgenic mice Am J Pathol 153 1998 639 648
    • (1998) Am J Pathol , vol.153 , pp. 639-648
    • Schirmacher, P.1    Peters, M.2    Ciliberto, G.3    Blessing, M.4    Lotz, J.5    Meyer Zum Buschenfelde, K.H.6
  • 46
    • 0032190524 scopus 로고    scopus 로고
    • Coexpression of IL-6 and soluble IL-6R causes nodular regenerative hyperplasia and adenomas of the liver
    • D. Maione, E. Di Carlo, W. Li, P. Musiani, A. Modesti, and M. Peters Coexpression of IL-6 and soluble IL-6R causes nodular regenerative hyperplasia and adenomas of the liver EMBO J 17 1998 5588 5597
    • (1998) EMBO J , vol.17 , pp. 5588-5597
    • Maione, D.1    Di Carlo, E.2    Li, W.3    Musiani, P.4    Modesti, A.5    Peters, M.6
  • 48
    • 0037462645 scopus 로고    scopus 로고
    • The N-terminal truncated isoform of SOCS3 translated from an alternative initiation AUG codon under stress conditions is stable due to the lack of a major ubiquitination site, Lys-6
    • A. Sasaki, K. Inagaki-Ohara, T. Yoshida, A. Yamanaka, M. Sasaki, and H. Yasukawa The N-terminal truncated isoform of SOCS3 translated from an alternative initiation AUG codon under stress conditions is stable due to the lack of a major ubiquitination site, Lys-6 J Biol Chem 278 2003 2432 2436
    • (2003) J Biol Chem , vol.278 , pp. 2432-2436
    • Sasaki, A.1    Inagaki-Ohara, K.2    Yoshida, T.3    Yamanaka, A.4    Sasaki, M.5    Yasukawa, H.6


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