-
1
-
-
0035884456
-
Chloroquine-resistance malaria
-
Wellems T, Plowe C. Chloroquine-resistance malaria. J Infect Dis 2001; 184: 770-6.
-
(2001)
J Infect Dis
, vol.184
, pp. 770-776
-
-
Wellems, T.1
Plowe, C.2
-
2
-
-
0036185240
-
Basis for antifolate action and resistance in malaria
-
Yuthavong Y. Basis for antifolate action and resistance in malaria. Microb Infect 2002; 4: 175-82.
-
(2002)
Microb Infect
, vol.4
, pp. 175-182
-
-
Yuthavong, Y.1
-
3
-
-
33646952828
-
Metal complexes for therapy and diagnosis of drug resistance
-
Sharma V, Piwnica-Worms D. Metal complexes for therapy and diagnosis of drug resistance. Chem Rev 1999; 99: 2545-60.
-
(1999)
Chem Rev
, vol.99
, pp. 2545-2560
-
-
Sharma, V.1
Piwnica-Worms, D.2
-
4
-
-
0000020457
-
Synthesis of metal complexes of antimalarial drugs and in vitro evaluation of their activity against Plasmodium falciparum
-
Wasi N, Singh HB, Gajanana, A, Raichowdhary AN. Synthesis of metal complexes of antimalarial drugs and in vitro evaluation of their activity against Plasmodium falciparum. Inorg Chim Acta 1987; 135: 133-7.
-
(1987)
Inorg Chim Acta
, vol.135
, pp. 133-137
-
-
Wasi, N.1
Singh, H.B.2
Gajanana, A.3
Raichowdhary, A.N.4
-
5
-
-
0029988639
-
Toward a novel metal-based chemotherapy against tropical diseases. 2. Synthesis and antimalarial activity in vitro and in vivo of new ruthenium- and rhodium-chloroquine complexes
-
Sanchez-Delgado R, Navarro M, Perez H, Urbina JA. Toward a novel metal-based chemotherapy against tropical diseases. 2. Synthesis and antimalarial activity in vitro and in vivo of new ruthenium- and rhodium-chloroquine complexes. J Med Chem 1996; 39: 1095-9.
-
(1996)
J Med Chem
, vol.39
, pp. 1095-1099
-
-
Sanchez-Delgado, R.1
Navarro, M.2
Perez, H.3
Urbina, J.A.4
-
7
-
-
46149135430
-
Metallocenes in biochemistry, microbiology and medicine
-
Dombrowski KE, Baldwin W, Sheats JE. Metallocenes in biochemistry, microbiology and medicine. J Organ Chem 1986; 302: 292-306.
-
(1986)
J Organ Chem
, vol.302
, pp. 292-306
-
-
Dombrowski, K.E.1
Baldwin, W.2
Sheats, J.E.3
-
8
-
-
33748672608
-
The biochemical reactions of organometallics with enzymes and proteins
-
Ryabov AD. The biochemical reactions of organometallics with enzymes and proteins. Angew Chem Int Ed Engl 1991; 30: 931-41.
-
(1991)
Angew Chem Int Ed Engl
, vol.30
, pp. 931-941
-
-
Ryabov, A.D.1
-
9
-
-
9844247985
-
Synthesis and antimalarial activity in vitro and in vivo of a new ferrocene-chloroquine analogue
-
Biot C, Glorian G, Maciejewski LA, Brocard JS, Domarle O, Blampain G, et al. Synthesis and antimalarial activity in vitro and in vivo of a new ferrocene-chloroquine analogue. J Med Chem 1997; 40: 3715-8.
-
(1997)
J Med Chem
, vol.40
, pp. 3715-3718
-
-
Biot, C.1
Glorian, G.2
Maciejewski, L.A.3
Brocard, J.S.4
Domarle, O.5
Blampain, G.6
-
10
-
-
0002438936
-
Novel metallocenic compounds as anti-malarial agents. Study of the position of ferrocene in chloroquine
-
Biot C, Delhaes L, Abessolo H, Domarle O, Maciejewski LA, Mortuaire M, et al. Novel metallocenic compounds as anti-malarial agents. Study of the position of ferrocene in chloroquine. J Organomet Chem 1999; 589: 59-65.
-
(1999)
J Organomet Chem
, vol.589
, pp. 59-65
-
-
Biot, C.1
Delhaes, L.2
Abessolo, H.3
Domarle, O.4
Maciejewski, L.A.5
Mortuaire, M.6
-
11
-
-
0036905135
-
Synthesis of ferroquine enantiomers: First investigation of effects of metallocenic chirality upon anti-malarial activity and cytotoxicity
-
Delhaes L, Biot C, Berry L, Delcourt P, Maciejewski LA, Camus D, et al. Synthesis of ferroquine enantiomers: first investigation of effects of metallocenic chirality upon anti-malarial activity and cytotoxicity. ChemBioChem 2002; 3: 418-23.
-
(2002)
ChemBioChem
, vol.3
, pp. 418-423
-
-
Delhaes, L.1
Biot, C.2
Berry, L.3
Delcourt, P.4
Maciejewski, L.A.5
Camus, D.6
-
12
-
-
0035090876
-
In vitro and in vivo antimalarial activity of ferrochloroquine, a ferrocenyl analogue of chloroquine against chloroquine-resistant malaria parasites
-
Delhaes L, Abessolo H, Biot C, Berry L, Delcourt P, Maciejewski LA, et al. In vitro and in vivo antimalarial activity of ferrochloroquine, a ferrocenyl analogue of chloroquine against chloroquine-resistant malaria parasites. Parasitol Res 2001; 87: 239-44.
-
(2001)
Parasitol Res
, vol.87
, pp. 239-244
-
-
Delhaes, L.1
Abessolo, H.2
Biot, C.3
Berry, L.4
Delcourt, P.5
Maciejewski, L.A.6
-
13
-
-
0034883927
-
Ferrocene-chloroquine analogues as antimalarial agents: In vitro activity of ferrochloroquine against 103 Gabonese isolates of Plasmodium falciparum
-
Pradines B, Fusai T, Daries W, Laloge V, Rogier C, Millet P, et al. Ferrocene-chloroquine analogues as antimalarial agents: in vitro activity of ferrochloroquine against 103 Gabonese isolates of Plasmodium falciparum. J Antimicrob Chemother 2001; 48: 179-84.
-
(2001)
J Antimicrob Chemother
, vol.48
, pp. 179-184
-
-
Pradines, B.1
Fusai, T.2
Daries, W.3
Laloge, V.4
Rogier, C.5
Millet, P.6
-
14
-
-
0036207647
-
In vitro activities of ferrochloroquine against 55 Senegalese isolates of Plasmodium falciparum in comparison with those of standard antimalarial drugs
-
Pradines B, Tall A, Rogier C, Spiegel A, Mosnier J, Marrama L, et al In vitro activities of ferrochloroquine against 55 Senegalese isolates of Plasmodium falciparum in comparison with those of standard antimalarial drugs. Trop Med Int Health 2002; 7: 265-70.
-
(2002)
Trop Med Int Health
, vol.7
, pp. 265-270
-
-
Pradines, B.1
Tall, A.2
Rogier, C.3
Spiegel, A.4
Mosnier, J.5
Marrama, L.6
-
15
-
-
0242684594
-
In vitro susceptibility to a new antimalarial organometallic analogue, ferroquine, of Plasmodium falciparum isolates from the Haut-Ogooué region of Gabon
-
Atteke C, Mezui Me Ndong J, Aubouy A, Maciejewski L, Brocard J, Lébidi J, et al. In vitro susceptibility to a new antimalarial organometallic analogue, ferroquine, of Plasmodium falciparum isolates from the Haut-Ogooué region of Gabon. J Antimicrob Chemother 2003; 51: 1021-4.
-
(2003)
J Antimicrob Chemother
, vol.51
, pp. 1021-1024
-
-
Atteke, C.1
Mezui Me Ndong, J.2
Aubouy, A.3
Maciejewski, L.4
Brocard, J.5
Lébidi, J.6
-
16
-
-
3142594018
-
The in-vitro antimalarial activity of ferrochloroquine, measured against Cambodian isolates of Plasmodium falciparum
-
Chim P, Lim P, Sem R, Nhem S, Maciejewski L, Fandeur T. The in-vitro antimalarial activity of ferrochloroquine, measured against Cambodian isolates of Plasmodium falciparum. Ann Trop Med Parasitol 2004; 98: 419-24.
-
(2004)
Ann Trop Med Parasitol
, vol.98
, pp. 419-424
-
-
Chim, P.1
Lim, P.2
Sem, R.3
Nhem, S.4
Maciejewski, L.5
Fandeur, T.6
-
17
-
-
0026514177
-
Inhibition by chloroquine of a novel haem polymerase enzyme activity in malaria trophozoites
-
Slater AF, Cerami A. Inhibition by chloroquine of a novel haem polymerase enzyme activity in malaria trophozoites. Nature 1992; 355: 167-9.
-
(1992)
Nature
, vol.355
, pp. 167-169
-
-
Slater, A.F.1
Cerami, A.2
-
18
-
-
0025255254
-
Hemoglobin degradation in the malaria parasite Plasmodium falciparum: An ordered process in a unique organelle
-
Goldberg DE, Slater AF, Cerami A, Henderson GB. Hemoglobin degradation in the malaria parasite Plasmodium falciparum: an ordered process in a unique organelle. Proc Natl Acad Sci USA 1990; 87: 2931-5.
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 2931-2935
-
-
Goldberg, D.E.1
Slater, A.F.2
Cerami, A.3
Henderson, G.B.4
-
19
-
-
0031847499
-
A microtitre-based method for measuring the haem polymerisation inhibitory activity (HPIA) of antimalarial drugs
-
Basilico N, Pagani E, Monti D, Olliaro P, Taramelli D. A microtitre-based method for measuring the haem polymerisation inhibitory activity (HPIA) of antimalarial drugs. J Antimicrob Chemother 1998; 42: 55-60.
-
(1998)
J Antimicrob Chemother
, vol.42
, pp. 55-60
-
-
Basilico, N.1
Pagani, E.2
Monti, D.3
Olliaro, P.4
Taramelli, D.5
-
20
-
-
0033523894
-
Structural specificity of chloroquine-hematin binding related to inhibition of hematin polymerisation and parasite growth
-
Vippagunta SR, Dom A, Matile H, Bhattacharjee AK, Karle JM, Ellis WY, et al. Structural specificity of chloroquine-hematin binding related to inhibition of hematin polymerisation and parasite growth. J Med Chem 1999; 42: 4630-9.
-
(1999)
J Med Chem
, vol.42
, pp. 4630-4639
-
-
Vippagunta, S.R.1
Dom, A.2
Matile, H.3
Bhattacharjee, A.K.4
Karle, J.M.5
Ellis, W.Y.6
-
21
-
-
0033636607
-
Mutations in the P. falciparum digestive vacuole transmembrane protein PfCRT and evidence for their role in chloroquine resistance
-
Fidock DA, Nomura T, Talley AK, Cooper RA, Dzekunov SM, Ferdig MT, et al. Mutations in the P. falciparum digestive vacuole transmembrane protein PfCRT and evidence for their role in chloroquine resistance. Mol Cell 2000; 6: 861-71.
-
(2000)
Mol Cell
, vol.6
, pp. 861-871
-
-
Fidock, D.A.1
Nomura, T.2
Talley, A.K.3
Cooper, R.A.4
Dzekunov, S.M.5
Ferdig, M.T.6
-
22
-
-
0035945682
-
A molecular marker for chloroquine-resistant falciparum malaria
-
Djimdé A, Doumbo OK, Cortese JF, Kayentao K, Doumbo S, Diourté Y, et al. A molecular marker for chloroquine-resistant falciparum malaria. N Engl J Med 2001; 344: 257-63.
-
(2001)
N Engl J Med
, vol.344
, pp. 257-263
-
-
Djimdé, A.1
Doumbo, O.K.2
Cortese, J.F.3
Kayentao, K.4
Doumbo, S.5
Diourté, Y.6
-
23
-
-
0035946415
-
Analysis of pfcrt point mutations and chloroquine susceptibility in isolates of Plasmodium falciparum
-
Durand R, Jafari S, Vauzelle J, Delabre JF, Jesic Z, Le Bras J. Analysis of pfcrt point mutations and chloroquine susceptibility in isolates of Plasmodium falciparum. Mol Biochem Parasitol 2001; 114: 95-102.
-
(2001)
Mol Biochem Parasitol
, vol.114
, pp. 95-102
-
-
Durand, R.1
Jafari, S.2
Vauzelle, J.3
Delabre, J.F.4
Jesic, Z.5
Le Bras, J.6
-
24
-
-
0033762883
-
Novel ferrocenic artemisinin derivatives: Synthesis, in vitro antimalarial activity and affinity of binding with ferroprotoporphyrin IX
-
Delhaes L, Biot C, Berry L, Maciejewski LA, Camus D, Brocard JS, et al. Novel ferrocenic artemisinin derivatives: synthesis, in vitro antimalarial activity and affinity of binding with ferroprotoporphyrin IX. Bioorg Med Chem 2000; 8: 2739-45.
-
(2000)
Bioorg Med Chem
, vol.8
, pp. 2739-2745
-
-
Delhaes, L.1
Biot, C.2
Berry, L.3
Maciejewski, L.A.4
Camus, D.5
Brocard, J.S.6
-
25
-
-
0033942879
-
Synthetic ferrocenic mefloquine and quinine analogues as potential antimalarial agents
-
Biot C, Delhaes L, Maciejewski LA, Mortuaire M, Camus D, Dive D, et al. Synthetic ferrocenic mefloquine and quinine analogues as potential antimalarial agents. Eur J Med Chem 2000; 35: 707-14.
-
(2000)
Eur J Med Chem
, vol.35
, pp. 707-714
-
-
Biot, C.1
Delhaes, L.2
Maciejewski, L.A.3
Mortuaire, M.4
Camus, D.5
Dive, D.6
-
26
-
-
0024338609
-
Amplification of the multidrug resistance gene in some chloroquine resistant isolates of P. falciparum
-
Foote SJ, Thompson JK, Cowman AF, Kemp DJ. Amplification of the multidrug resistance gene in some chloroquine resistant isolates of P. falciparum. Cell 1989; 57: 921-30.
-
(1989)
Cell
, vol.57
, pp. 921-930
-
-
Foote, S.J.1
Thompson, J.K.2
Cowman, A.F.3
Kemp, D.J.4
-
27
-
-
0025786518
-
A P-glycoprotein homologue of Plasmodium falciparum is isolated on the digestive vacuole
-
Cowman AF, Karcz S, Galatis D, Culvenor JG. A P-glycoprotein homologue of Plasmodium falciparum is isolated on the digestive vacuole. J Cell Biol 1991; 113: 1033-45.
-
(1991)
J Cell Biol
, vol.113
, pp. 1033-1045
-
-
Cowman, A.F.1
Karcz, S.2
Galatis, D.3
Culvenor, J.G.4
-
28
-
-
0027406890
-
Nucleotide binding properties of a P-glycoprotein homologue from Plasmodium falciparum
-
Karcz SR, Galatis D, Cowman AF. Nucleotide binding properties of a P-glycoprotein homologue from Plasmodium falciparum. Mol Biochem Parasitol 1993; 55: 269-76.
-
(1993)
Mol Biochem Parasitol
, vol.55
, pp. 269-276
-
-
Karcz, S.R.1
Galatis, D.2
Cowman, A.F.3
-
29
-
-
0023666563
-
Efflux of chloroquine from Plasmodium falciparum: Mechanism of chloroquine resistance
-
Krogstad DJ, Gluzman IY, Kyle DE, Oduola AMJ, Martin SK, Milhous WK, et al. Efflux of chloroquine from Plasmodium falciparum: mechanism of chloroquine resistance. Science 1987; 235: 1283-5.
-
(1987)
Science
, vol.235
, pp. 1283-1285
-
-
Krogstad, D.J.1
Gluzman, I.Y.2
Kyle, D.E.3
Oduola, A.M.J.4
Martin, S.K.5
Milhous, W.K.6
-
31
-
-
0028607543
-
Enhanced lysosomal acidification leads to increased chloroquine accumulation in CHO cells expressing the pfmdr1 gene
-
Van Es HHG, Renkema H, Aerts H, Schurr E. Enhanced lysosomal acidification leads to increased chloroquine accumulation in CHO cells expressing the pfmdr1 gene. Mol Biochem Parasitol 1994; 65: 209-19.
-
(1994)
Mol Biochem Parasitol
, vol.65
, pp. 209-219
-
-
Van Es, H.H.G.1
Renkema, H.2
Aerts, H.3
Schurr, E.4
-
32
-
-
0030965449
-
Probing the chloroquine resistance locus of Plasmodium falciparum with a novel class of multidentate metal(in) coordination complexes
-
Goldberg DE, Sharma V, Oksman A, Gluzman IY, Wellems TE, Piwnica-Worms D. Probing the chloroquine resistance locus of Plasmodium falciparum with a novel class of multidentate metal(in) coordination complexes. J Biol Chem 1997; 272: 6567-72.
-
(1997)
J Biol Chem
, vol.272
, pp. 6567-6572
-
-
Goldberg, D.E.1
Sharma, V.2
Oksman, A.3
Gluzman, I.Y.4
Wellems, T.E.5
Piwnica-Worms, D.6
-
33
-
-
0242586013
-
Metalloantimalarials: Targeting of P. falciparum strains with novel iron(III) and gallium(ni) complexes of an amine phenol ligand
-
Harpstrite SE, Beatty AA, Collins SD, Oksman A, Goldberg DE, Sharma V. Metalloantimalarials: targeting of P. falciparum strains with novel iron(III) and gallium(ni) complexes of an amine phenol ligand. Inorg Chem 2003; 42: 2294-300.
-
(2003)
Inorg Chem
, vol.42
, pp. 2294-2300
-
-
Harpstrite, S.E.1
Beatty, A.A.2
Collins, S.D.3
Oksman, A.4
Goldberg, D.E.5
Sharma, V.6
-
34
-
-
0034673656
-
The structure of malaria pigment β-haematin
-
Pagola S, Stephens PW, Bohle DS, Kosar AD, Madsen SK. The structure of malaria pigment β-haematin. Nature 2000; 404: 307-10.
-
(2000)
Nature
, vol.404
, pp. 307-310
-
-
Pagola, S.1
Stephens, P.W.2
Bohle, D.S.3
Kosar, A.D.4
Madsen, S.K.5
-
35
-
-
0032520664
-
An assessment of drug-haematin binding as a mechanism for inhibition of haematin polymerization by quinoline antimalarials
-
Dorn A, Vippagunta SR, Matile H, Jaquet C, Vennerstrom JL, Ridley RG. An assessment of drug-haematin binding as a mechanism for inhibition of haematin polymerization by quinoline antimalarials. Biochem Pharmacol 1998; 55: 727-36.
-
(1998)
Biochem Pharmacol
, vol.55
, pp. 727-736
-
-
Dorn, A.1
Vippagunta, S.R.2
Matile, H.3
Jaquet, C.4
Vennerstrom, J.L.5
Ridley, R.G.6
-
36
-
-
0031916653
-
Relationship between antimalarial drug activity, accumulation, and inhibition of heme polymerisation in Plasmodium falciparum in vitro
-
Hawley SR, Bray PG, Mungthin M, Atkinson JD, O'Neill PM, Ward SA. Relationship between antimalarial drug activity, accumulation, and inhibition of heme polymerisation in Plasmodium falciparum in vitro. Antimicrob Agents Chemother 1998; 42: 682-6.
-
(1998)
Antimicrob Agents Chemother
, vol.42
, pp. 682-686
-
-
Hawley, S.R.1
Bray, P.G.2
Mungthin, M.3
Atkinson, J.D.4
O'Neill, P.M.5
Ward, S.A.6
-
37
-
-
0030034651
-
Haemolysis of Plasmodium falciparum trophozoite-infected erythrocytes after artemisinin exposure
-
Orjih AU. Haemolysis of Plasmodium falciparum trophozoite-infected erythrocytes after artemisinin exposure. Br J Haematol 1996; 92: 324-8.
-
(1996)
Br J Haematol
, vol.92
, pp. 324-328
-
-
Orjih, A.U.1
-
38
-
-
0033516474
-
Artemisinin, an endoperoxyde antimalarial, disrupt the hemoglobin catabolism and heme detoxification system in malarial parasite
-
Pandey AV, Tekwani BL, Singh RL, Chauban VS. Artemisinin, an endoperoxyde antimalarial, disrupt the hemoglobin catabolism and heme detoxification system in malarial parasite. J Biol Chem 1999; 274: 19383-8.
-
(1999)
J Biol Chem
, vol.274
, pp. 19383-19388
-
-
Pandey, A.V.1
Tekwani, B.L.2
Singh, R.L.3
Chauban, V.S.4
-
39
-
-
0029844272
-
Effects of multidrug resistance (MDR1) P-glycoprotein expression levels and coordination metal on the cytotoxic potency of multidentate (N4O2) (ethylenediamine)bis[propyl(R-benzylimino)] metal (III) cations
-
Sharma V, Crankshaw CL, Piwnica-Worms D. Effects of multidrug resistance (MDR1) P-glycoprotein expression levels and coordination metal on the cytotoxic potency of multidentate (N4O2) (ethylenediamine)bis[propyl(R-benzylimino)] metal (III) cations. J Med Chem 1996; 39: 3483-90.
-
(1996)
J Med Chem
, vol.39
, pp. 3483-3490
-
-
Sharma, V.1
Crankshaw, C.L.2
Piwnica-Worms, D.3
-
40
-
-
0037439861
-
Synthesis, characterization, and molecular structure of a gallium (IU) complex of an amine-phenol ligand with activity against chloroquine-sensitive Plasmodium falciparum strains
-
Ocheskey JA, Polyakov VR, Harpstrite SE, Oksman A, Goldberg DE, Piwnica-Worms D, et al. Synthesis, characterization, and molecular structure of a gallium (IU) complex of an amine-phenol ligand with activity against chloroquine-sensitive Plasmodium falciparum strains. J Inorg Biochem 2003; 93: 265-70.
-
(2003)
J Inorg Biochem
, vol.93
, pp. 265-270
-
-
Ocheskey, J.A.1
Polyakov, V.R.2
Harpstrite, S.E.3
Oksman, A.4
Goldberg, D.E.5
Piwnica-Worms, D.6
-
41
-
-
0038799864
-
Transition metal complexes of buparvaquone as potent new antimalarial agents. 1. Synthesis, X-ray crystal-structures, electrochemistry and antimalarial activity against Plasmodium falciparum
-
Gokhale NH, Padhye SB, Croft SL, Kendrick HD, Davies W, Anson CE, et al. Transition metal complexes of buparvaquone as potent new antimalarial agents. 1. Synthesis, X-ray crystal-structures, electrochemistry and antimalarial activity against Plasmodium falciparum. J Inorg Biochem 2003; 95: 249-58.
-
(2003)
J Inorg Biochem
, vol.95
, pp. 249-258
-
-
Gokhale, N.H.1
Padhye, S.B.2
Croft, S.L.3
Kendrick, H.D.4
Davies, W.5
Anson, C.E.6
-
42
-
-
0028818933
-
Synthesis and biological activity of novel metal complexes of 2-acetylpyridine thiosemicarbazones
-
Offiong OE, Martelli S. Synthesis and biological activity of novel metal complexes of 2-acetylpyridine thiosemicarbazones. Il Farmaco 1995; 50: 625-32.
-
(1995)
Il Farmaco
, vol.50
, pp. 625-632
-
-
Offiong, O.E.1
Martelli, S.2
-
43
-
-
0030513325
-
Synthesis and biological activity of platinum group metal complexes of o-vanillin thiosemicarbazones
-
Offiong OE, Etok C, Martelli S. Synthesis and biological activity of platinum group metal complexes of o-vanillin thiosemicarbazones. Il Farmaco 1996; 51: 801-8.
-
(1996)
Il Farmaco
, vol.51
, pp. 801-808
-
-
Offiong, O.E.1
Etok, C.2
Martelli, S.3
-
44
-
-
0034618158
-
Synthesis of novel ferrocenyl sugars and their anti-malarial activities
-
Itoh T, Shirakami S, Ishida N, Yamashita Y, Yoshida T, Kim HS, et al. Synthesis of novel ferrocenyl sugars and their anti-malarial activities. Bioorg Med Chem Lett 2000; 10: 1657-9.
-
(2000)
Bioorg Med Chem Lett
, vol.10
, pp. 1657-1659
-
-
Itoh, T.1
Shirakami, S.2
Ishida, N.3
Yamashita, Y.4
Yoshida, T.5
Kim, H.S.6
-
45
-
-
0029113622
-
Effects of zinc-desferrioxamine on Plasmodium falciparum in culture
-
Chevion M, Chuang L, Golenser J. Effects of zinc-desferrioxamine on Plasmodium falciparum in culture. Antimicrob Agents Chemother 1995; 39: 1902-5.
-
(1995)
Antimicrob Agents Chemother
, vol.39
, pp. 1902-1905
-
-
Chevion, M.1
Chuang, L.2
Golenser, J.3
-
46
-
-
0025102616
-
Parasite uptake of desferrioxamine: A prerequisite for anti-malarial activity
-
Scott MD, Ranz A, Kuypers FA, Lubin BH, Meschnick SR. Parasite uptake of desferrioxamine: a prerequisite for anti-malarial activity. Br J Haematol 1990; 75: 598-603.
-
(1990)
Br J Haematol
, vol.75
, pp. 598-603
-
-
Scott, M.D.1
Ranz, A.2
Kuypers, F.A.3
Lubin, B.H.4
Meschnick, S.R.5
-
47
-
-
0027392073
-
The antimalarial action of Desferal involves a direct access route to erythrocytic (Plasmodium falciparum) parasites
-
Loyevsky M, Lytton SD, Mester B, Libman J, Shanzer A, Cabantchik ZI. The antimalarial action of Desferal involves a direct access route to erythrocytic (Plasmodium falciparum) parasites. J Clin Invest 1993; 91: 218-24.
-
(1993)
J Clin Invest
, vol.91
, pp. 218-224
-
-
Loyevsky, M.1
Lytton, S.D.2
Mester, B.3
Libman, J.4
Shanzer, A.5
Cabantchik, Z.I.6
-
48
-
-
0019948542
-
Plasmodium falciparum: Inhibition of in vitro growth by desferrioxamine
-
Raventos-Suarez C, Pollack S, Nagel RL. Plasmodium falciparum: inhibition of in vitro growth by desferrioxamine. Am J Trop Med Hyg 1982; 31: 919-22.
-
(1982)
Am J Trop Med Hyg
, vol.31
, pp. 919-922
-
-
Raventos-Suarez, C.1
Pollack, S.2
Nagel, R.L.3
-
50
-
-
0025088403
-
Stage-dependent effect of deferoxamine on growth of Plasmodium falciparum in vitro
-
Whitehead S, Peto TE. Stage-dependent effect of deferoxamine on growth of Plasmodium falciparum in vitro. Blood 1990; 76: 1250-5.
-
(1990)
Blood
, vol.76
, pp. 1250-1255
-
-
Whitehead, S.1
Peto, T.E.2
-
51
-
-
0142008820
-
Chélation du fer dans la thérapie antipaludique
-
Pradines B, Millet J, Henry M. Chélation du fer dans la thérapie antipaludique. Med Trop 2003; 63: 119-30.
-
(2003)
Med Trop
, vol.63
, pp. 119-130
-
-
Pradines, B.1
Millet, J.2
Henry, M.3
-
52
-
-
0031792787
-
Inhibition of glutathione-dependent degradation of heme by chloroquine and amodiaquine as possible basis for their antimalarial mode of action
-
Ginsburg H, Famin O, Zhang J, Krugliak M. Inhibition of glutathione-dependent degradation of heme by chloroquine and amodiaquine as possible basis for their antimalarial mode of action. Biochem Pharmacol 1998; 56: 1305-13.
-
(1998)
Biochem Pharmacol
, vol.56
, pp. 1305-1313
-
-
Ginsburg, H.1
Famin, O.2
Zhang, J.3
Krugliak, M.4
-
53
-
-
0030879653
-
Hemoglobin metabolism in the malaria parasite Plasmodium falciparum
-
Francis SE, Sullivan DJ, Goldberg DE. Hemoglobin metabolism in the malaria parasite Plasmodium falciparum. Annu Rev Microbiol 1997; 51: 97-123.
-
(1997)
Annu Rev Microbiol
, vol.51
, pp. 97-123
-
-
Francis, S.E.1
Sullivan, D.J.2
Goldberg, D.E.3
-
54
-
-
0025255254
-
Hemoglobin degradation in the malaria parasite Plasmodium falciparum: An ordered process in a unique organelle
-
Goldberg DE, Slater AFG, Cerami A, Henderson GB. Hemoglobin degradation in the malaria parasite Plasmodium falciparum: an ordered process in a unique organelle. Proc Natl Acad Sci USA 1990; 87: 2931-5.
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 2931-2935
-
-
Goldberg, D.E.1
Slater, A.F.G.2
Cerami, A.3
Henderson, G.B.4
-
55
-
-
0025959212
-
An iron-carboxylate bond links the heme units of malaria pigment
-
Slater AFG, Swiggard WJ, Orton BR, Flitter WO, Goldberg DE, Cerami A, et al. An iron-carboxylate bond links the heme units of malaria pigment. Proc Natl Acad Sci USA 1991; 88: 325-9.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 325-329
-
-
Slater, A.F.G.1
Swiggard, W.J.2
Orton, B.R.3
Flitter, W.O.4
Goldberg, D.E.5
Cerami, A.6
-
56
-
-
0019188940
-
Ferriprotoporphyrin IX fulfils the criteria for identification as the chloroquine receptor of malaria parasites
-
Chou AC, Chevli R, Fitch CD. Ferriprotoporphyrin IX fulfils the criteria for identification as the chloroquine receptor of malaria parasites. Biochem 1980; 19: 1543-9.
-
(1980)
Biochem
, vol.19
, pp. 1543-1549
-
-
Chou, A.C.1
Chevli, R.2
Fitch, C.D.3
-
57
-
-
0027998464
-
Quinoline antimalarial drugs inhibit spontaneous formation of β-haematin (malaria pigment)
-
Egan TJ, Ross DC, Adams PA. Quinoline antimalarial drugs inhibit spontaneous formation of β-haematin (malaria pigment). FEBS Lett 1994; 352: 54-7.
-
(1994)
FEBS Lett
, vol.352
, pp. 54-57
-
-
Egan, T.J.1
Ross, D.C.2
Adams, P.A.3
-
58
-
-
0029752982
-
Inhibition of hemozoin formation in Plasmodium falciparum trophozoite extracts by heme analogs: Possible implication in the resistance to malaria conferred by the β-thalassemia trait
-
Martiney JA, Cerami A, Slater AFG. Inhibition of hemozoin formation in Plasmodium falciparum trophozoite extracts by heme analogs: possible implication in the resistance to malaria conferred by the β-thalassemia trait. Mol Med 1996; 2: 236-46.
-
(1996)
Mol Med
, vol.2
, pp. 236-246
-
-
Martiney, J.A.1
Cerami, A.2
Slater, A.F.G.3
-
59
-
-
0031007845
-
Non-iron porphyrins inhibit β-haematin (malaria pigment) polymerisation
-
Basilico N, Monti D, Olliaro P, Taramelli D. Non-iron porphyrins inhibit β-haematin (malaria pigment) polymerisation. FEBS Lett 1997; 409: 297-9.
-
(1997)
FEBS Lett
, vol.409
, pp. 297-299
-
-
Basilico, N.1
Monti, D.2
Olliaro, P.3
Taramelli, D.4
-
60
-
-
0033551480
-
A novel endogenous antimalarial: Fe(II)-protoporphyrin IX α (heme) inhibits hematin polymerization to β-hematin (malaria pigment) and kills malaria parasites
-
Monti D, Vodopivec B, Basilico N, Olliaro P, Taramelli D. A novel endogenous antimalarial: Fe(II)-protoporphyrin IX α (heme) inhibits hematin polymerization to β-hematin (malaria pigment) and kills malaria parasites. Biochem 1999; 38: 8858-63.
-
(1999)
Biochem
, vol.38
, pp. 8858-8863
-
-
Monti, D.1
Vodopivec, B.2
Basilico, N.3
Olliaro, P.4
Taramelli, D.5
-
62
-
-
0032841393
-
Potentiation of artemisinin activity against chloroquine-resistant Plasmodium falciparum strains by using heme models
-
Benoit-Vical F, Robert A, Meunier B. Potentiation of artemisinin activity against chloroquine-resistant Plasmodium falciparum strains by using heme models. Antimicrob Agents Chemother 1999; 43: 2555-8.
-
(1999)
Antimicrob Agents Chemother
, vol.43
, pp. 2555-2558
-
-
Benoit-Vical, F.1
Robert, A.2
Meunier, B.3
-
63
-
-
0033802634
-
In vitro and in vivo potentiation of artemisinin and synthetic endoperoxide antimalarial drugs by metalloporphyrins
-
Benoit-Vical F, Robert A, Meunier B. In vitro and in vivo potentiation of artemisinin and synthetic endoperoxide antimalarial drugs by metalloporphyrins. Antimicrob Agents Chemother 2000; 44: 2836-41.
-
(2000)
Antimicrob Agents Chemother
, vol.44
, pp. 2836-2841
-
-
Benoit-Vical, F.1
Robert, A.2
Meunier, B.3
-
64
-
-
0038686310
-
In vitro antimalarial activity of metalloporphyrins against Plasmodium falciparum
-
Begum K, Kim HS, Kumar V, Stojiljkovic I, Wataya Y. In vitro antimalarial activity of metalloporphyrins against Plasmodium falciparum. Parasitol Res 2003; 90: 221-4.
-
(2003)
Parasitol Res
, vol.90
, pp. 221-224
-
-
Begum, K.1
Kim, H.S.2
Kumar, V.3
Stojiljkovic, I.4
Wataya, Y.5
-
65
-
-
0005289665
-
Artemisin antimalarials: Mechanisms of action and resistance
-
Meshnick SR. Artemisin antimalarials: mechanisms of action and resistance. Med Trop 1998; 58: 13-7.
-
(1998)
Med Trop
, vol.58
, pp. 13-17
-
-
Meshnick, S.R.1
-
67
-
-
0001123285
-
Antimalarial activity of artemisinin (qinghaosu) and related trioxanes: Mechanisms of action
-
Cumming JN, Ploypradith P, Posner G. Antimalarial activity of artemisinin (qinghaosu) and related trioxanes: mechanisms of action. Adv Pharmacol 1997; 37: 253-97.
-
(1997)
Adv Pharmacol
, vol.37
, pp. 253-297
-
-
Cumming, J.N.1
Ploypradith, P.2
Posner, G.3
-
68
-
-
0028109346
-
Reaction of antimalarial endoperoxides with specific parasite proteins
-
Asawamahsakda W, Ittarat I, Pu YM, Ziffer H, Meschnick SR. Reaction of antimalarial endoperoxides with specific parasite proteins. Antimicrob Agents Chemother 1994; 38: 1854-8.
-
(1994)
Antimicrob Agents Chemother
, vol.38
, pp. 1854-1858
-
-
Asawamahsakda, W.1
Ittarat, I.2
Pu, Y.M.3
Ziffer, H.4
Meschnick, S.R.5
-
70
-
-
0031041266
-
Correlation of antimalarial activity of artemisinin derivatives with binding affinity with ferroprotoporphyrine IX
-
Paitayatat S, Tarnchompoo B, Thebtaranonth Y, Yuthavong Y. Correlation of antimalarial activity of artemisinin derivatives with binding affinity with ferroprotoporphyrine IX. J Med Chem 1997; 40: 633-8.
-
(1997)
J Med Chem
, vol.40
, pp. 633-638
-
-
Paitayatat, S.1
Tarnchompoo, B.2
Thebtaranonth, Y.3
Yuthavong, Y.4
-
71
-
-
0026014249
-
Artemisinin (qinghaosu): The role of intracellular hemin in its mechanism of antimalarial action
-
Meshnick SR, Thomas A, Ranz A, Xu CM, Pan HZ. Artemisinin (qinghaosu): the role of intracellular hemin in its mechanism of antimalarial action. Mol Biochem Parasitol 1991; 49: 181-9.
-
(1991)
Mol Biochem Parasitol
, vol.49
, pp. 181-189
-
-
Meshnick, S.R.1
Thomas, A.2
Ranz, A.3
Xu, C.M.4
Pan, H.Z.5
-
72
-
-
0027990218
-
Enhancement of hemin-induced membrane damage by artemisinin
-
Wei N, Sadrzadeh SMH. Enhancement of hemin-induced membrane damage by artemisinin. Biochem Pharmacol 1994; 48: 737-41.
-
(1994)
Biochem Pharmacol
, vol.48
, pp. 737-741
-
-
Wei, N.1
Sadrzadeh, S.M.H.2
-
73
-
-
0029112920
-
Molecular modeling studies of the artemisinin-hemin interaction: Docking between the antimalarial agent and its putative receptor
-
Shukla K, Gund TM, Meshnick SR. Molecular modeling studies of the artemisinin-hemin interaction: docking between the antimalarial agent and its putative receptor. J Mol Graphics 1995; 13: 215-22.
-
(1995)
J Mol Graphics
, vol.13
, pp. 215-222
-
-
Shukla, K.1
Gund, T.M.2
Meshnick, S.R.3
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