Metalloantimalarials: Targeting of P. falciparum strains with novel iron(III) and gallium(III) complexes of an amine phenol ligand

Inorganic Chemistry

Volumn 42, Issue 7, 2003, Pages 2294-2300

  Harpstrite, Scott E ^a   Beatty, Alicia A ^b   Collins, Silvia D ^a   Oksman, Anna ^c   Goldberg, Daniel E ^c   Sharma, Vijay ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NOTRE DAME   (United States)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

[1,12 BIS(2 HYDROXY 3 ETHYLBENZYL) 1,5,8,12 TETRAAZADODECANE]GALLIUM DERIVATIVE; [1,12 BIS(2 HYDROXY 3 ETHYLBENZYL) 1,5,8,12 TETRAAZADODECANE]IRON DERIVATIVE; AMINE; ANTIMALARIAL AGENT; CHLOROQUINE; CYTOTOXIC AGENT; FERRIC ION; GALLIUM; HEMOZOIN; IRON DERIVATIVE; LIGAND; PHENOL DERIVATIVE; UNCLASSIFIED DRUG;

ANTIMALARIAL ACTIVITY; ARTICLE; CATION TRANSPORT; CRYSTAL STRUCTURE; DRUG COST; DRUG CYTOTOXICITY; DRUG POTENCY; DRUG STRUCTURE; DRUG TARGETING; ECONOMIC ASPECT; GEOMETRY; HEALTH CARE ACCESS; HEALTH CARE DISTRIBUTION; HYDROPHOBICITY; IC 50; INCUBATION TIME; METAL BINDING; MOLECULAR STABILITY; NONHUMAN; PLASMODIUM FALCIPARUM; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SENSITIVITY ANALYSIS; SEQUENCE HOMOLOGY; STRAIN IDENTIFICATION; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

AMINES; ANIMALS; ANTIMALARIALS; CELL LINE; CHLOROQUINE; DRUG RESISTANCE; FERRIC COMPOUNDS; GALLIUM; INHIBITORY CONCENTRATION 50; LIGANDS; MOLECULAR STRUCTURE; ORGANOMETALLIC COMPOUNDS; PARASITIC SENSITIVITY TESTS; PHENOL; PLASMODIUM FALCIPARUM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0242586013     PISSN: 00201669     EISSN: None     Source Type: Journal    
DOI: 10.1021/ic034036e     Document Type: Article

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