Loss of the von Hippel Lindau tumor suppressor disrupts iron homeostasis in renal carcinoma cells

Journal of Biological Chemistry

Volumn 280, Issue 34, 2005, Pages 30120-30128

  Alberghini, Alessandra ^a   Recalcati, Stefania ^a   Tacchini, Lorenza ^a   Santambrogio, Paolo ^b,c   Campanella, Alessandro ^b,c   Cairo, Gaetano ^a  

^a UNIVERSITY OF MILAN   (Italy)

^b SAN RAFFAELE HOSPITAL   (Italy)

^c FONDAZIONE IRCCS CA GRANDA OSPEDALE MAGGIORE POLICLINICO   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; CLONING; DISEASES; GENES; IRON; METABOLISM; MUTAGENESIS; OXIDATION; PROTEINS;

IRON REGULATORY PROTEINS 2 (IRP2); LABILE IRON POOL; TRANSFACTANT CLONE; VON HIPPEL LINDAU (VHL);

TUMORS;

FERRITIN; HYPOXIA INDUCIBLE FACTOR 1; IRON 55; IRON REGULATORY PROTEIN 1; IRON REGULATORY PROTEIN 2; MESSENGER RNA; PROTEIN SUBUNIT; TRANSFERRIN; TRANSFERRIN RECEPTOR; VON HIPPEL LINDAU PROTEIN;

ARTICLE; CANCER CELL CULTURE; CELL ASSAY; CELL CLONE; CELL DAMAGE; CELL DIVISION; CELL LEVEL; CELL PROLIFERATION; CELL PROTECTION; CONTROLLED STUDY; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE LOSS; GENE MUTATION; GENETIC TRANSFECTION; HOMEOSTASIS; HUMAN; HUMAN CELL; IRON BALANCE; IRON METABOLISM; IRON TRANSPORT; KIDNEY CARCINOMA; LABILE IRON POOL; OXIDATIVE STRESS; PARAMETER; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; RECEPTOR UPREGULATION; REGULATORY MECHANISM; TRANSCRIPTION INITIATION; TUMOR SUPPRESSOR GENE; WILD TYPE;

ACONITATE HYDRATASE; ANOXIA; BLOTTING, NORTHERN; CARCINOMA; CELL LINE, TUMOR; CELL PROLIFERATION; DNA, COMPLEMENTARY; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME-LINKED IMMUNOSORBENT ASSAY; FERRITINS; HISTIDINE; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; IMMUNOBLOTTING; IRON; IRON REGULATORY PROTEIN 2; KIDNEY NEOPLASMS; LUCIFERASES; NUCLEAR PROTEINS; OXIDANTS; PROMOTER REGIONS (GENETICS); PROTEIN STRUCTURE, TERTIARY; RNA; RNA, MESSENGER; TIME FACTORS; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TRANSFECTION; TRANSFERRIN; TUMOR SUPPRESSOR PROTEINS; UBIQUITIN-PROTEIN LIGASES; VON HIPPEL-LINDAU TUMOR SUPPRESSOR PROTEIN;

EID: 24044554883     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M500971200     Document Type: Article

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