Doxorubicin paradoxically protects cardiomyocytes against iron-mediated toxicity: Role of reactive oxygen species and ferritin

Journal of Biological Chemistry

Volumn 279, Issue 14, 2004, Pages 13738-13745

  Corna, Gianfranca ^a   Santambrogio, Paolo ^b   Minotti, Giorgio ^c   Cairo, Gaetano ^a  

^a UNIVERSITY OF MILAN   (Italy)

^b SAN RAFFAELE HOSPITAL   (Italy)

^c UNIVERSITY OF CHIETI   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

AMMONIUM COMPOUNDS; BIOSYNTHESIS; CARDIOLOGY; ENZYMES; GENES; GLUCOSE; IRON; OXIDATION; RNA; TOXICITY;

CARDIOMYOCYTES; CARDIOTOXICITY; OXIDATIVE DAMAGE;

BIOCHEMICAL ENGINEERING;

5 IMINODAUNORUBICIN; ACETYLCYSTEINE; ALDEHYDE REDUCTASE; CATALASE; DICHLORODIHYDROFLUORESCEIN; DOXORUBICIN; FERRIC AMMONIUM CITRATE; FERRITIN; FLUORESCEIN; GLUCOSE; GLUCOSE OXIDASE; HYDROGEN PEROXIDE; IRON; IRON 55; IRON REGULATORY PROTEIN 2; MESSENGER RNA; MITOXANTRONE; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CARDIOTOXICITY; CELL PROTECTION; CONTROLLED STUDY; DRUG STRUCTURE; EMBRYO; GENE EXPRESSION; GENETIC TRANSCRIPTION; HEART MUSCLE CELL; HEART PROTECTION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RAT;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; CELL LINE; DOXORUBICIN; DRUG INTERACTIONS; FERRITINS; GENE EXPRESSION REGULATION; IRON; MYOCYTES, CARDIAC; OXIDATIVE STRESS; RATS; REACTIVE OXYGEN SPECIES;

ANIMALIA;

EID: 1842690698     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M310106200     Document Type: Article

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