The C-terminal domain of the β cell homeodomain factor Nkx6.1 enhances sequence-selective DNA binding at the insulin promoter

Biochemistry

Volumn 44, Issue 33, 2005, Pages 11269-11278

  Taylor, David G ^a   Babu, Daniella ^a   Mirmira, Raghavendra G ^a,b  

^a UNIVERSITY OF VIRGINIA   (United States)

^b UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CONFORMATIONS; DNA; FUNCTIONS; GELS; INSULIN; MATHEMATICAL MODELS; SPECTROSCOPIC ANALYSIS;

CELL HOMEODOMAIN FACTOR; CIRCULAR DICHROISM SPECTROSCOPY; GEL SHIFT ANALYSIS; INSULIN PROMOTER;

CELLS;

AMINO ACID; HOMEODOMAIN FACTOR NKX6.1; HOMEODOMAIN FACTOR PDX 1; HOMEODOMAIN PROTEIN; INSULIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CIRCULAR DICHROISM; CONTROLLED STUDY; DNA SEQUENCE; GEL MOBILITY SHIFT ASSAY; GENE DELETION; GENE MUTATION; GENE TARGETING; GENETIC CONSERVATION; HUMAN; INSULIN RELEASE; MAMMAL CELL; MOLECULAR RECOGNITION; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN CONFORMATION; PROTEIN DNA BINDING; PROTEIN SECONDARY STRUCTURE; QUANTITATIVE ANALYSIS; REPORTER GENE; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; TRANSCRIPTION TERMINATION;

ANIMALS; GENE EXPRESSION REGULATION; HOMEODOMAIN PROTEINS; HUMANS; INSULIN; ISLETS OF LANGERHANS; MICE; MOLECULAR STRUCTURE; NIH 3T3 CELLS; PROMOTER REGIONS (GENETICS); PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RATS; RESPONSE ELEMENTS; SEQUENCE DELETION; TRANSCRIPTION, GENETIC;

MAMMALIA;

EID: 23944494573     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi050821m     Document Type: Article

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