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Volumn 50, Issue 7, 2005, Pages 321-328

Genetic diversity and new therapeutic concepts

Author keywords

Gene; Medicine; Pharmacogenetics; Pharmacogenomics; Polymorphism

Indexed keywords

6 MERCAPTOPURINE DERIVATIVE; ABACAVIR; ABC TRANSPORTER; AZATHIOPRINE; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CARRIER PROTEIN; CIMETIDINE; CIPROFLOXACIN; CLOZAPINE; CODEINE; CYCLOSPORIN; CYTOCHROME P450 ISOENZYME; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIURETIC AGENT; DOCETAXEL; DRUG METABOLIZING ENZYME; EFAVIRENZ; ENZYME INHIBITOR; FLUOROURACIL; GEMCITABINE; IRINOTECAN; METHOTREXATE; MULTIDRUG RESISTANCE PROTEIN; PHENYTOIN; PRAVASTATIN; PREDNISONE; RNA DIRECTED DNA POLYMERASE INHIBITOR; TACROLIMUS; UNINDEXED DRUG; WARFARIN;

EID: 23944484940     PISSN: 14345161     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10038-005-0264-6     Document Type: Short Survey
Times cited : (47)

References (95)
  • 2
    • 0033608466 scopus 로고    scopus 로고
    • Association of polymorphism in the cytochrome P450 CYP2C9 with warfarin dose requirement and risk of bleeding complications
    • Aithal GP, Day CP, Kesteven PJ, Daly AK (1999) Association of polymorphism in the cytochrome P450 CYP2C9 with warfarin dose requirement and risk of bleeding complications. Lancet 353:717-719
    • (1999) Lancet , vol.353 , pp. 717-719
    • Aithal, G.P.1    Day, C.P.2    Kesteven, P.J.3    Daly, A.K.4
  • 3
    • 0348218980 scopus 로고    scopus 로고
    • Neuropeptide gene polymorphisms and human behavioral disorders
    • Akio I (2003) Neuropeptide gene polymorphisms and human behavioral disorders. Nat Rev Drug Discov 2:986-998
    • (2003) Nat Rev Drug Discov , vol.2 , pp. 986-998
    • Akio, I.1
  • 5
    • 10044278020 scopus 로고    scopus 로고
    • Pharmacogenetics of antihypertensive treatment
    • Arnett DK, Claas SA (2004) Pharmacogenetics of antihypertensive treatment. Drug Dev Res 62:191-199
    • (2004) Drug Dev Res , vol.62 , pp. 191-199
    • Arnett, D.K.1    Claas, S.A.2
  • 6
    • 0033486093 scopus 로고    scopus 로고
    • Application of pharmacogenetics to optimization of mercaptopurine dosing
    • Balis FM, Adamson PC (1999) Application of pharmacogenetics to optimization of mercaptopurine dosing. J Natl Cancer Inst 91:1983-1984
    • (1999) J Natl Cancer Inst , vol.91 , pp. 1983-1984
    • Balis, F.M.1    Adamson, P.C.2
  • 8
    • 11144234127 scopus 로고    scopus 로고
    • Genes and the response to drugs
    • Caraco Y (2004) Genes and the response to drugs. N Engl J Med 351:2867-2869
    • (2004) N Engl J Med , vol.351 , pp. 2867-2869
    • Caraco, Y.1
  • 9
    • 8644234912 scopus 로고    scopus 로고
    • Inference from the relationships between linkage disequilibrium and allele frequency distribution of 240 candidate SNPs in 109 drug-related genes in four Asian populations
    • Cha PC, Yamada R, Sekine A, Nakamura Y, Koh CL (2004) Inference from the relationships between linkage disequilibrium and allele frequency distribution of 240 candidate SNPs in 109 drug-related genes in four Asian populations. J Hum Genet 49:558-572
    • (2004) J Hum Genet , vol.49 , pp. 558-572
    • Cha, P.C.1    Yamada, R.2    Sekine, A.3    Nakamura, Y.4    Koh, C.L.5
  • 10
    • 10044263002 scopus 로고    scopus 로고
    • Pharmacogenetics of human carboxylesterase 2, an enzyme involved in the activation of irinotecan into SN-38
    • Charasson V, Bellott R, Meynard D, Lougy M, Gorry P, Robert J (2004) Pharmacogenetics of human carboxylesterase 2, an enzyme involved in the activation of irinotecan into SN-38. Clin Pharmacol Ther 76:528-535
    • (2004) Clin Pharmacol Ther , vol.76 , pp. 528-535
    • Charasson, V.1    Bellott, R.2    Meynard, D.3    Lougy, M.4    Gorry, P.5    Robert, J.6
  • 12
    • 6044272744 scopus 로고    scopus 로고
    • Single nucleotide polymorphisms and haplotypes of histamine- N-methyltransferase in patients with gastric ulcer
    • Chen GL, Zhu B, Nie WP, Xu ZH, Tan ZR, Zhou G, Liu J, Wang W, Zhou HH (2004) Single nucleotide polymorphisms and haplotypes of histamine- N-methyltransferase in patients with gastric ulcer. Inflamm Res 53:484-488
    • (2004) Inflamm Res , vol.53 , pp. 484-488
    • Chen, G.L.1    Zhu, B.2    Nie, W.P.3    Xu, Z.H.4    Tan, Z.R.5    Zhou, G.6    Liu, J.7    Wang, W.8    Zhou, H.H.9
  • 13
    • 10644241977 scopus 로고    scopus 로고
    • Pharmacogenetics of the cytochrome P450
    • Daly AK (2004) Pharmacogenetics of the cytochrome P450. Curr Top Med Chem 4:1733-1744
    • (2004) Curr Top Med Chem , vol.4 , pp. 1733-1744
    • Daly, A.K.1
  • 14
    • 4444381535 scopus 로고    scopus 로고
    • ABCG2 pharmacogenetics: Ethnic difference in allelic frequency and assessment of influence on irinotecan disposition
    • De Jong FA, Marsh S, Mathijssen RHJ, King C, Verweij J, Sparreboom A, McLeod HL (2004) ABCG2 pharmacogenetics: ethnic difference in allelic frequency and assessment of influence on irinotecan disposition. Clin Cancer Res 10:5889-5894
    • (2004) Clin Cancer Res , vol.10 , pp. 5889-5894
    • De Jong, F.A.1    Marsh, S.2    Mathijssen, R.H.J.3    King, C.4    Verweij, J.5    Sparreboom, A.6    McLeod, H.L.7
  • 15
    • 16544362120 scopus 로고    scopus 로고
    • Pharmacogenetics in cancer chemotherapy-balancing toxicity and response
    • Donnelly JG (2004) Pharmacogenetics in cancer chemotherapy-balancing toxicity and response. Ther Drug Monitor 26:231-235
    • (2004) Ther Drug Monitor , vol.26 , pp. 231-235
    • Donnelly, J.G.1
  • 17
    • 4444378425 scopus 로고    scopus 로고
    • Catechol-O-methyltransferase low activity genotype (COMTLL) is associated with low levels of COMT protein in human hepatocyte
    • Doyle AES, Goodman JE, Silber PM, Yager JD (2004) Catechol-O- methyltransferase low activity genotype (COMTLL) is associated with low levels of COMT protein in human hepatocyte. Cancer Lett 214:189-195
    • (2004) Cancer Lett , vol.214 , pp. 189-195
    • Doyle, A.E.S.1    Goodman, J.E.2    Silber, P.M.3    Yager, J.D.4
  • 19
    • 0035775486 scopus 로고    scopus 로고
    • Pharmacogenomics: The inherited basis for interindividual differences in drug response
    • Evans WE, Johnson JA (2001) Pharmacogenomics: the inherited basis for interindividual differences in drug response. Annu Rev Genomics Hum Genet 2:9-39
    • (2001) Annu Rev Genomics Hum Genet , vol.2 , pp. 9-39
    • Evans, W.E.1    Johnson, J.A.2
  • 20
    • 0037421590 scopus 로고    scopus 로고
    • Pharmacogenomics - Drug disposition, drug targets and side effects
    • Evans WE, McLeod HL (2003) Pharmacogenomics - drug disposition, drug targets and side effects. N Engl J Med 348:538-549
    • (2003) N Engl J Med , vol.348 , pp. 538-549
    • Evans, W.E.1    McLeod, H.L.2
  • 21
    • 2642570170 scopus 로고    scopus 로고
    • Moving towards individualized medicine with pharmacogenomics
    • Evans WE, Relling MV (2004) Moving towards individualized medicine with pharmacogenomics. Nature 429:464-468
    • (2004) Nature , vol.429 , pp. 464-468
    • Evans, W.E.1    Relling, M.V.2
  • 22
    • 9944221077 scopus 로고    scopus 로고
    • The impact of thiopurine 5-methyltransferase polymorphism on a azathioprine dose 1 year after renal transplantation
    • Fabre MA, Jones DC, Bunce M, Morris PJ, Friend PJ, Welsh KI, Marshall SC (2004) The impact of thiopurine 5-methyltransferase polymorphism on a azathioprine dose 1 year after renal transplantation. Transpl Int 17:531-539
    • (2004) Transpl Int , vol.17 , pp. 531-539
    • Fabre, M.A.1    Jones, D.C.2    Bunce, M.3    Morris, P.J.4    Friend, P.J.5    Welsh, K.I.6    Marshall, S.C.7
  • 23
    • 11044229099 scopus 로고    scopus 로고
    • Pharmacogenetics/ pharmacogenomics and anti-rheumatic drugs in rheumatology
    • Ferraccioli G, De Santis M, Tolusso B (2004) Pharmacogenetics/ pharmacogenomics and anti-rheumatic drugs in rheumatology. Pharmacogenomics 5:1107-1116
    • (2004) Pharmacogenomics , vol.5 , pp. 1107-1116
    • Ferraccioli, G.1    De Santis, M.2    Tolusso, B.3
  • 24
    • 2942726419 scopus 로고    scopus 로고
    • Challenges of personalized health care: To what extent is medicine already individualized and what are the future trends?
    • Fierz W (2004) Challenges of personalized health care: to what extent is medicine already individualized and what are the future trends? Med Sci Monitor 10:RA111-RA123
    • (2004) Med Sci Monitor , vol.10
    • Fierz, W.1
  • 27
    • 5044242910 scopus 로고    scopus 로고
    • Identification and analysis of single nucleotide polymorphisms in the gemcitabine pharmacologic pathway
    • Fukunaga AK, Marsh S, Murray DJ, Hurley TD, McLeod HL (2004) Identification and analysis of single nucleotide polymorphisms in the gemcitabine pharmacologic pathway. Pharmacogenomics J 4:307-314
    • (2004) Pharmacogenomics J , vol.4 , pp. 307-314
    • Fukunaga, A.K.1    Marsh, S.2    Murray, D.J.3    Hurley, T.D.4    McLeod, H.L.5
  • 31
    • 0035010640 scopus 로고    scopus 로고
    • Automation in genotyping of single nucleotide polymorphisms
    • Gut I (2001) Automation in genotyping of single nucleotide polymorphisms. Hum Mutat 17:475-492
    • (2001) Hum Mutat , vol.17 , pp. 475-492
    • Gut, I.1
  • 32
    • 10044233991 scopus 로고    scopus 로고
    • Pharmacogenomics of antiretroviral therapy
    • Haas DW (2004b) Pharmacogenomics of antiretroviral therapy. Drug Dev Res 62:213-220
    • (2004) Drug Dev Res , vol.62 , pp. 213-220
    • Haas, D.W.1
  • 34
    • 9644288047 scopus 로고    scopus 로고
    • Role of pharmacogenomics in drug development
    • Hakonarsson H, Stefansson K (2004) Role of pharmacogenomics in drug development. Drug Dev Res 62:86-96
    • (2004) Drug Dev Res , vol.62 , pp. 86-96
    • Hakonarsson, H.1    Stefansson, K.2
  • 35
    • 9644281174 scopus 로고    scopus 로고
    • Pharmacogenetics in drug development: Regulatory and clinical considerations
    • Hall ST, Abbott N, Schmith G, Brazell C (2004) Pharmacogenetics in drug development: regulatory and clinical considerations. Drug Dev Res 62:102-111
    • (2004) Drug Dev Res , vol.62 , pp. 102-111
    • Hall, S.T.1    Abbott, N.2    Schmith, G.3    Brazell, C.4
  • 36
    • 6044223415 scopus 로고    scopus 로고
    • High-dose venlafaxine treatment in a depressed patient with a genetic CYP2D6 deficiency
    • Haller-Gloor F, Eap CB, Turgeon J, Baumann P (2004) High-dose venlafaxine treatment in a depressed patient with a genetic CYP2D6 deficiency. Int J Psychiatry Clin Pract 8:191-195
    • (2004) Int J Psychiatry Clin Pract , vol.8 , pp. 191-195
    • Haller-Gloor, F.1    Eap, C.B.2    Turgeon, J.3    Baumann, P.4
  • 37
    • 7544229429 scopus 로고    scopus 로고
    • Pharmacology, drug efficacy and the individual
    • Hildebrandt AG (2004) Pharmacology, drug efficacy and the individual. Drug Metab Rev 36:845-852
    • (2004) Drug Metab Rev , vol.36 , pp. 845-852
    • Hildebrandt, A.G.1
  • 39
    • 4744365530 scopus 로고    scopus 로고
    • Dosage recommendation of phenytoin for patients with epilepsy with different CYP2C9/CYP2C19 polymorphisms
    • Hung CC, Lin CJ, Chen CC, Chang CJ, Liou HH (2004) Dosage recommendation of phenytoin for patients with epilepsy with different CYP2C9/CYP2C19 polymorphisms. Ther Drug Monit 26:534-540
    • (2004) Ther Drug Monit , vol.26 , pp. 534-540
    • Hung, C.C.1    Lin, C.J.2    Chen, C.C.3    Chang, C.J.4    Liou, H.H.5
  • 41
    • 0027136288 scopus 로고
    • Inherited amplification of an active gene in the cytochrome P450 CYP2D locus as a cause of ultra-rapid metabolism of debrisoquine
    • Johansson I, Lindqvist E, Bertilsson L, Dahl ML, Sjoqvist F, Ingelman-Sundberg M (1993) Inherited amplification of an active gene in the cytochrome P450 CYP2D locus as a cause of ultra-rapid metabolism of debrisoquine. Proc Natl Acad Sci USA 90:11825-11829
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 11825-11829
    • Johansson, I.1    Lindqvist, E.2    Bertilsson, L.3    Dahl, M.L.4    Sjoqvist, F.5    Ingelman-Sundberg, M.6
  • 42
    • 11844304376 scopus 로고    scopus 로고
    • Clinical consequences of cytochrome P450 2C9 polymorphism
    • Kirchheiner J, Brockmoller J (2005) Clinical consequences of cytochrome P450 2C9 polymorphism. Clin Pharmacol Ther 77:1-16
    • (2005) Clin Pharmacol Ther , vol.77 , pp. 1-16
    • Kirchheiner, J.1    Brockmoller, J.2
  • 44
    • 6944230851 scopus 로고    scopus 로고
    • The effect of variable CYP3A expression on cyclosporine dosing, blood pressure and long-term graft survival in renal transplant patients
    • Kreutz R, Zurcher H, Kain S, Martus P, Offerman G, Beige J (2004) The effect of variable CYP3A expression on cyclosporine dosing, blood pressure and long-term graft survival in renal transplant patients. Pharmacogenetics 14:665-671
    • (2004) Pharmacogenetics , vol.14 , pp. 665-671
    • Kreutz, R.1    Zurcher, H.2    Kain, S.3    Martus, P.4    Offerman, G.5    Beige, J.6
  • 45
    • 0242312707 scopus 로고    scopus 로고
    • Drug methylation in cancer therapy: Lessons from the TPMT polymorphism
    • Krynetski E, Evans WE (2003) Drug methylation in cancer therapy: lessons from the TPMT polymorphism. Oncogene 22:7403-7413
    • (2003) Oncogene , vol.22 , pp. 7403-7413
    • Krynetski, E.1    Evans, W.E.2
  • 47
  • 49
    • 0032522873 scopus 로고    scopus 로고
    • Incidence of adverse drug reactions in hospitalized patients
    • Lazarou J, Pomeranz BH, Corey PN (1998) Incidence of adverse drug reactions in hospitalized patients. JAMA 297:1200-1205
    • (1998) JAMA , vol.297 , pp. 1200-1205
    • Lazarou, J.1    Pomeranz, B.H.2    Corey, P.N.3
  • 50
    • 4143069198 scopus 로고    scopus 로고
    • CYP2C9 genotype as a predictor of drug deposition in humans
    • Lee CR (2004) CYP2C9 genotype as a predictor of drug deposition in humans. Methods Find Exp Clin Pharmacol 26:463-472
    • (2004) Methods Find Exp Clin Pharmacol , vol.26 , pp. 463-472
    • Lee, C.R.1
  • 51
    • 3042848593 scopus 로고    scopus 로고
    • Pharmacogenetics of the human MDR1 multidrug transporter
    • Lee CG, Chong SS, Lee EJD (2004) Pharmacogenetics of the human MDR1 multidrug transporter. Curr Pharmacogenomics 2:1-11
    • (2004) Curr Pharmacogenomics , vol.2 , pp. 1-11
    • Lee, C.G.1    Chong, S.S.2    Lee, E.J.D.3
  • 52
    • 4544335467 scopus 로고    scopus 로고
    • Translation of pharmacogenomics and pharmacogenetics: A regulatory perspective
    • Lesko LJ, Woodcock J (2004) Translation of pharmacogenomics and pharmacogenetics: a regulatory perspective. Nat Rev Drug Discov 3:763-769
    • (2004) Nat Rev Drug Discov , vol.3 , pp. 763-769
    • Lesko, L.J.1    Woodcock, J.2
  • 54
    • 4444220954 scopus 로고    scopus 로고
    • The use of DNA microarray in the pharmacogenetics of antidepressants: Guidelines for a targeted approach
    • Lorenzi C, Tubazio V, Serretti A, De Ronchi D (2004) The use of DNA microarray in the pharmacogenetics of antidepressants: guidelines for a targeted approach. Curr Genomics 5:499-508
    • (2004) Curr Genomics , vol.5 , pp. 499-508
    • Lorenzi, C.1    Tubazio, V.2    Serretti, A.3    De Ronchi, D.4
  • 55
    • 0007293059 scopus 로고    scopus 로고
    • Ultrarapid metabolizers of debrisoquine: Characterization and PCR-based detection of alleles with duplication of the CYP2D6 gene
    • Lovlie R, Daly AK, Molven A, Idle JR, Steen VM (1996) Ultrarapid metabolizers of debrisoquine: characterization and PCR-based detection of alleles with duplication of the CYP2D6 gene. FEBS Lett 392:30-34
    • (1996) FEBS Lett , vol.392 , pp. 30-34
    • Lovlie, R.1    Daly, A.K.2    Molven, A.3    Idle, J.R.4    Steen, V.M.5
  • 56
    • 9144253194 scopus 로고    scopus 로고
    • MDR1 haplotypes derived from exons 21 and 26 do not affect the steady-state pharmacokinetics of tacrolimus in renal transplant patients
    • Mai I, Perloff ES, Bauer S, Goldammer M, Johne A, Filler G, Budde K, Roots I (2004) MDR1 haplotypes derived from exons 21 and 26 do not affect the steady-state pharmacokinetics of tacrolimus in renal transplant patients. Br J Clin Pharmacol 58:548-553
    • (2004) Br J Clin Pharmacol , vol.58 , pp. 548-553
    • Mai, I.1    Perloff, E.S.2    Bauer, S.3    Goldammer, M.4    Johne, A.5    Filler, G.6    Budde, K.7    Roots, I.8
  • 58
    • 4544311452 scopus 로고    scopus 로고
    • Pharmacogenetics of antiretroviral therapy: Genetic variation of response and toxicity
    • Martin AM, Nolan D, Gaudier S, Phillips E, Mallal S (2004) Pharmacogenetics of antiretroviral therapy: genetic variation of response and toxicity. Pharmacogenomics 5:643-655
    • (2004) Pharmacogenomics , vol.5 , pp. 643-655
    • Martin, A.M.1    Nolan, D.2    Gaudier, S.3    Phillips, E.4    Mallal, S.5
  • 59
    • 0036009619 scopus 로고    scopus 로고
    • The thiopurine S-methyltransferase gene locus - Implications for clinical pharmacogenomics
    • McLeod H, Siva C (2002) The thiopurine S-methyltransferase gene locus - implications for clinical pharmacogenomics. Pharmacogenomics 3:89-98
    • (2002) Pharmacogenomics , vol.3 , pp. 89-98
    • McLeod, H.1    Siva, C.2
  • 60
    • 4344574336 scopus 로고    scopus 로고
    • Pharmacogenetics: Five decades of therapeutic lessons from genetic diversity
    • Meyer UA (2004) Pharmacogenetics: five decades of therapeutic lessons from genetic diversity. Nat Rev Genet 5:669-676
    • (2004) Nat Rev Genet , vol.5 , pp. 669-676
    • Meyer, U.A.1
  • 61
    • 0030782422 scopus 로고    scopus 로고
    • Adverse drug reaction monitoring cost and benefit consideration: Frequency of adverse drug reactions causing hospital admissions
    • Muehlberger N, Schneeweiss S, Hasford J (1997) Adverse drug reaction monitoring cost and benefit consideration: frequency of adverse drug reactions causing hospital admissions. Pharmacoepidemiol Drug Saf 6:S71-S77
    • (1997) Pharmacoepidemiol Drug Saf , vol.6
    • Muehlberger, N.1    Schneeweiss, S.2    Hasford, J.3
  • 62
    • 0037785185 scopus 로고    scopus 로고
    • Cardiovascular disease
    • Nabel EG (2003) Cardiovascular disease. N Engl J Med 349:60-72
    • (2003) N Engl J Med , vol.349 , pp. 60-72
    • Nabel, E.G.1
  • 64
    • 4644359361 scopus 로고    scopus 로고
    • Advances in pharmacogenomics and individualized drug therapy: Exciting challenges that lie ahead
    • Nebert DW, Vesell ES (2004) Advances in pharmacogenomics and individualized drug therapy: exciting challenges that lie ahead. Eur J Pharmacol 500:267-280
    • (2004) Eur J Pharmacol , vol.500 , pp. 267-280
    • Nebert, D.W.1    Vesell, E.S.2
  • 65
    • 0038294345 scopus 로고    scopus 로고
    • Pharmacogenetics of drug metabolizing enzymes: Importance for personalized medicine
    • Oscarson M (2003) Pharmacogenetics of drug metabolizing enzymes: importance for personalized medicine. Clin Chem Lab Med 41:573-580
    • (2003) Clin Chem Lab Med , vol.41 , pp. 573-580
    • Oscarson, M.1
  • 66
    • 9644263928 scopus 로고    scopus 로고
    • Genotype and allele frequencies of C3435T polymorphism of the MDR1 gene in various Jewish populations of Israel
    • Ostrovsky O, Nagler A, Korostishevsky M, Gazet E, Galski H (2004) Genotype and allele frequencies of C3435T polymorphism of the MDR1 gene in various Jewish populations of Israel. Ther Drug Monitor 26:679-684
    • (2004) Ther Drug Monitor , vol.26 , pp. 679-684
    • Ostrovsky, O.1    Nagler, A.2    Korostishevsky, M.3    Gazet, E.4    Galski, H.5
  • 72
    • 4344684441 scopus 로고    scopus 로고
    • Pharmacogenetics and drug development: The path to safer and more effective drugs
    • Roses AD (2004) Pharmacogenetics and drug development: the path to safer and more effective drugs. Nat Rev Genet 5:645-656
    • (2004) Nat Rev Genet , vol.5 , pp. 645-656
    • Roses, A.D.1
  • 73
    • 10044280433 scopus 로고    scopus 로고
    • Pharmacogenomic approaches in antidiabetic drug development
    • Rosmond R (2004) Pharmacogenomic approaches in antidiabetic drug development. Drug Dev Res 62:207-212
    • (2004) Drug Dev Res , vol.62 , pp. 207-212
    • Rosmond, R.1
  • 74
    • 4544373032 scopus 로고    scopus 로고
    • Pharmacogenetics of drug transporters and its impact on the pharmacotherapy
    • Sakaeda T, Nakamura T, Okumura K (2004) Pharmacogenetics of drug transporters and its impact on the pharmacotherapy. Curr Top Med Chem 4:1385-1398
    • (2004) Curr Top Med Chem , vol.4 , pp. 1385-1398
    • Sakaeda, T.1    Nakamura, T.2    Okumura, K.3
  • 76
    • 4544344215 scopus 로고    scopus 로고
    • Pharmacogenetics of dopamine receptors and response to antipsychotic drugs in schizophrenia: An update
    • Scharfetter J (2004) Pharmacogenetics of dopamine receptors and response to antipsychotic drugs in schizophrenia: an update. Pharmacogenomics 5:691-698
    • (2004) Pharmacogenomics , vol.5 , pp. 691-698
    • Scharfetter, J.1
  • 77
    • 4644255903 scopus 로고    scopus 로고
    • Ethnic variation in CYP2A6 and association of genetically slow nicotine metabolism and smoking in adults Caucasians
    • Schoedel KA, Hoffman EB, Rao Y, Sellers EM, Tyndale RF (2004) Ethnic variation in CYP2A6 and association of genetically slow nicotine metabolism and smoking in adults Caucasians. Pharmacogenetics 14:615-626
    • (2004) Pharmacogenetics , vol.14 , pp. 615-626
    • Schoedel, K.A.1    Hoffman, E.B.2    Rao, Y.3    Sellers, E.M.4    Tyndale, R.F.5
  • 78
    • 3442891124 scopus 로고    scopus 로고
    • SNPs and haplotypes: Genetic markers for disease and drug response
    • Shastry BS (2003) SNPs and haplotypes: genetic markers for disease and drug response. Int J Mol Med 11:379-382
    • (2003) Int J Mol Med , vol.11 , pp. 379-382
    • Shastry, B.S.1
  • 79
    • 9644303301 scopus 로고    scopus 로고
    • Role of SNP/haplotype map in gene discovery and drug development
    • Shastry BS (2004) Role of SNP/haplotype map in gene discovery and drug development. Drug Dev Res 62:143-150
    • (2004) Drug Dev Res , vol.62 , pp. 143-150
    • Shastry, B.S.1
  • 81
    • 10044257623 scopus 로고    scopus 로고
    • Recent advances in pharmacogenetic approaches to anticancer drug development
    • Smith NF, Figg WD, Sparreboom A (2004) Recent advances in pharmacogenetic approaches to anticancer drug development. Drug Dev Res 62:233-253
    • (2004) Drug Dev Res , vol.62 , pp. 233-253
    • Smith, N.F.1    Figg, W.D.2    Sparreboom, A.3
  • 83
    • 4544291786 scopus 로고    scopus 로고
    • Pharmacogenomics: The influence of genomic variation on drug response
    • Thomas FJ, McLeod HL, Watters JW (2004) Pharmacogenomics: the influence of genomic variation on drug response. Curr Top Med Chem 4:236-240
    • (2004) Curr Top Med Chem , vol.4 , pp. 236-240
    • Thomas, F.J.1    McLeod, H.L.2    Watters, J.W.3
  • 85
    • 0038345082 scopus 로고    scopus 로고
    • Prospects and limits of pharmacogenetics: The thiopurine methyltransferase (TPMT) experience
    • Van Aken J, Schmedders M, Feuerstein G, Kollek R (2003) Prospects and limits of pharmacogenetics: the thiopurine methyltransferase (TPMT) experience. Am J Pharmacogenomics 3:149-155
    • (2003) Am J Pharmacogenomics , vol.3 , pp. 149-155
    • Van Aken, J.1    Schmedders, M.2    Feuerstein, G.3    Kollek, R.4
  • 86
    • 1942453306 scopus 로고    scopus 로고
    • Dihydropyrimidine dehydrogenase and the efficacy and toxicity of 5-fluorouracil
    • Van Kuilenburg AB (2004) Dihydropyrimidine dehydrogenase and the efficacy and toxicity of 5-fluorouracil. Eur J Cancer 40:939-950
    • (2004) Eur J Cancer , vol.40 , pp. 939-950
    • Van Kuilenburg, A.B.1
  • 87
    • 16544383308 scopus 로고    scopus 로고
    • Implications of cytochrome P450 polymorphisms on the toxicity of antitumor agents
    • Van Schaik RHN (2004) Implications of cytochrome P450 polymorphisms on the toxicity of antitumor agents. Ther Drug Monitor 26:236-240
    • (2004) Ther Drug Monitor , vol.26 , pp. 236-240
    • Van Schaik, R.H.N.1
  • 90
    • 3342875407 scopus 로고    scopus 로고
    • Integrating pharmacogenetics into society: In search of a model
    • Webster A, Martin P, Lewis G, Smart A (2004) Integrating pharmacogenetics into society: in search of a model. Nat Rev Genet 9:663-669
    • (2004) Nat Rev Genet , vol.9 , pp. 663-669
    • Webster, A.1    Martin, P.2    Lewis, G.3    Smart, A.4
  • 91
    • 0037421584 scopus 로고    scopus 로고
    • Inheritance and drug response
    • Weinshilboum R (2003) Inheritance and drug response. N Engl J Med 348:529-537
    • (2003) N Engl J Med , vol.348 , pp. 529-537
    • Weinshilboum, R.1
  • 92
  • 93
    • 16544365185 scopus 로고    scopus 로고
    • Genetics of the variable expression of CYP3A in human
    • Wojnowski L (2004) Genetics of the variable expression of CYP3A in human. Ther Drug Monitor 26:192-199
    • (2004) Ther Drug Monitor , vol.26 , pp. 192-199
    • Wojnowski, L.1
  • 94
    • 0035028479 scopus 로고    scopus 로고
    • Molecular basis of ethnic differences in drug disposition and response
    • Xie HG, Kim RB, Wood AJ, Stein CM (2001) Molecular basis of ethnic differences in drug disposition and response. Annu Rev Pharmacol Toxicol 41:815-850
    • (2001) Annu Rev Pharmacol Toxicol , vol.41 , pp. 815-850
    • Xie, H.G.1    Kim, R.B.2    Wood, A.J.3    Stein, C.M.4
  • 95
    • 7044272271 scopus 로고    scopus 로고
    • Clinical and functional consequences of platelet membrane glycoprotein polymorphisms
    • Yee DL, Bray PF (2004) Clinical and functional consequences of platelet membrane glycoprotein polymorphisms. Semin Thromb Hemost 30:591-600
    • (2004) Semin Thromb Hemost , vol.30 , pp. 591-600
    • Yee, D.L.1    Bray, P.F.2


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