메뉴 건너뛰기




Volumn 17, Issue 5, 2004, Pages 253-261

Potential genetic influences on the response to asthma treatment

Author keywords

Asthma; Drug targets; Pharmacogenetics; Polymorphisms

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ACETYLSALICYLIC ACID; ANTIASTHMATIC AGENT; ANTIINFLAMMATORY AGENT; ARACHIDONATE 5 LIPOXYGENASE; ATRELEUTON; BETA 2 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; BUDESONIDE; CHOLINERGIC RECEPTOR BLOCKING AGENT; CORTICOSTEROID; DEXAMETHASONE; FORMOTEROL; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; HISTONE DEACETYLASE; IMIDAZOLE DERIVATIVE; LEUKOTRIENE; LEUKOTRIENE C4 SYNTHASE; LEUKOTRIENE RECEPTOR BLOCKING AGENT; LIPOXYGENASE INHIBITOR; METHACHOLINE; METHYLXANTHINE DERIVATIVE; MITOGEN ACTIVATED PROTEIN KINASE; MONTELUKAST; MUSCARINIC RECEPTOR; SALBUTAMOL; SALMETEROL; ZAFIRLUKAST; ZILEUTON;

EID: 5144230472     PISSN: 10945539     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pupt.2004.04.005     Document Type: Article
Times cited : (12)

References (81)
  • 1
    • 0035141851 scopus 로고    scopus 로고
    • The health economics of asthma and rhinitis. I. Assessing the economic impact
    • Weiss K.B., Sullivan S.D. The health economics of asthma and rhinitis. I. Assessing the economic impact. J Allergy Clin Immunol. 107:2001;3-8
    • (2001) J Allergy Clin Immunol , vol.107 , pp. 3-8
    • Weiss, K.B.1    Sullivan, S.D.2
  • 2
    • 0034017468 scopus 로고    scopus 로고
    • Pharmacogenetics of asthma
    • Hall I.P. Pharmacogenetics of asthma. Eur Respir J. 15:2000;449-451
    • (2000) Eur Respir J , vol.15 , pp. 449-451
    • Hall, I.P.1
  • 3
    • 0034443957 scopus 로고    scopus 로고
    • Heterogeneity of therapeutic responses in asthma
    • Drazen J.M., Silverman E.K., Lee T.H. Heterogeneity of therapeutic responses in asthma. Br Med Bull. 56:2000;1054-1070
    • (2000) Br Med Bull , vol.56 , pp. 1054-1070
    • Drazen, J.M.1    Silverman, E.K.2    Lee, T.H.3
  • 5
    • 0032997217 scopus 로고    scopus 로고
    • The essence of SNPs
    • Brookes A.J. The essence of SNPs. Gene. 8:1999;177-186
    • (1999) Gene , vol.8 , pp. 177-186
    • Brookes, A.J.1
  • 6
    • 0041506933 scopus 로고    scopus 로고
    • Pharmacology and physiology of human adrenergic receptor polymorphisms
    • Small K.M., McGraw D.W., Liggett S.B. Pharmacology and physiology of human adrenergic receptor polymorphisms. Annu Rev Pharmacol Toxicol. 43:2003;381-411
    • (2003) Annu Rev Pharmacol Toxicol , vol.43 , pp. 381-411
    • Small, K.M.1    McGraw, D.W.2    Liggett, S.B.3
  • 7
    • 0347925015 scopus 로고    scopus 로고
    • Personalized prescribing for asthma - Is pharmacogenetics the answer?
    • Dewar J.C., Hall I.P. Personalized prescribing for asthma - is pharmacogenetics the answer? J Pharm Pharmacol. 55:2003;279-289
    • (2003) J Pharm Pharmacol , vol.55 , pp. 279-289
    • Dewar, J.C.1    Hall, I.P.2
  • 11
    • 0028068550 scopus 로고
    • 2-adrenergic receptor impart distinct agonist-promoted regulatory properties
    • 2-adrenergic receptor impart distinct agonist-promoted regulatory properties. Biochemistry. 33:1994;9414-9419
    • (1994) Biochemistry , vol.33 , pp. 9414-9419
    • Green, S.A.1    Turki, J.2    Innis, M.3    Liggett, S.B.4
  • 13
    • 0030860288 scopus 로고    scopus 로고
    • 2-adrenoceptor polymorphism and susceptibility to bronchodilator desensitisation in moderately severe stable asthmatics
    • 2-adrenoceptor polymorphism and susceptibility to bronchodilator desensitisation in moderately severe stable asthmatics. Lancet. 350:1997;995-999
    • (1997) Lancet , vol.350 , pp. 995-999
    • Tan, S.1    Hall, I.P.2    Dewar, J.3    Dow, E.4    Lipworth, B.5
  • 14
    • 0031594494 scopus 로고    scopus 로고
    • 2-adrenoceptor regulation and bronchodilator sensitivity after regular treatment with formoterol in subjects with stable asthma
    • 2- adrenoceptor regulation and bronchodilator sensitivity after regular treatment with formoterol in subjects with stable asthma. J Allergy Clin Immunol. 101:1998;337-341
    • (1998) J Allergy Clin Immunol , vol.101 , pp. 337-341
    • Aziz, I.1    Hall, I.P.2    McFarlane, L.C.3    Lipworth, B.J.4
  • 19
    • 0029045292 scopus 로고
    • 2-adrenoceptor polymorphism with lower airway reactivity in asthmatic subjects
    • 2-adrenoceptor polymorphism with lower airway reactivity in asthmatic subjects. Lancet. 345:1995;1213-1214
    • (1995) Lancet , vol.345 , pp. 1213-1214
    • Hall, I.P.1    Wheatley, A.2    Wilding, P.3    Liggett, S.B.4
  • 20
    • 0027519404 scopus 로고
    • 2-adrenergic receptor within the fourth transmembrane domain alters ligand binding and functional properties of the receptor
    • 2-adrenergic receptor within the fourth transmembrane domain alters ligand binding and functional properties of the receptor. J Biol Chem. 268:1993;23116-23121
    • (1993) J Biol Chem , vol.268 , pp. 23116-23121
    • Green, S.A.1    Cole, G.2    Jacinto, M.3    Innis, M.4    Liggett, S.B.5
  • 23
    • 0028145741 scopus 로고
    • 2-adrenergic receptor mRNA inhibits receptor synthesis
    • 2-adrenergic receptor mRNA inhibits receptor synthesis. J Biol Chem. 269:1994;4497-4505
    • (1994) J Biol Chem , vol.269 , pp. 4497-4505
    • Parola, A.L.1    Kobilka, B.K.2
  • 26
    • 0033953714 scopus 로고    scopus 로고
    • 2-adrenergic receptors: Relevance to asthma
    • 2-adrenergic receptors: relevance to asthma. J Allergy Clin Immunol. 105:2000;S487-S492
    • (2000) J Allergy Clin Immunol , vol.105
    • Liggett, S.B.1
  • 29
    • 0034129679 scopus 로고    scopus 로고
    • Steroid hormone receptors: An update
    • Beato M., Klug J. Steroid hormone receptors: an update. Hum Reprod Update. 6:2000;225-236
    • (2000) Hum Reprod Update , vol.6 , pp. 225-236
    • Beato, M.1    Klug, J.2
  • 30
    • 0030026713 scopus 로고    scopus 로고
    • Molecular determinants of glucocorticoid receptor function and tissue sensitivity to glucocorticoids
    • Bamberger C.M., Schulte H.M., Chrousos G.P. Molecular determinants of glucocorticoid receptor function and tissue sensitivity to glucocorticoids. Endocrinol Rev. 17:1996;245-261
    • (1996) Endocrinol Rev , vol.17 , pp. 245-261
    • Bamberger, C.M.1    Schulte, H.M.2    Chrousos, G.P.3
  • 31
    • 0033323794 scopus 로고    scopus 로고
    • Insertion of an amino acid in the DNA-binding domain of the glucocorticoid receptor as a result of alternative splicing
    • Rivers C., Levy A., Hancock J., Lighman S., Norman M. Insertion of an amino acid in the DNA-binding domain of the glucocorticoid receptor as a result of alternative splicing. J Clin Endocrinol Metab. 84:1999;4283-4286
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 4283-4286
    • Rivers, C.1    Levy, A.2    Hancock, J.3    Lighman, S.4    Norman, M.5
  • 35
    • 0037268987 scopus 로고    scopus 로고
    • Molecular determinants of glucocorticoid sensitivity and resistance in acute lymphoblastic leukemia
    • Tissing W.J.E., Meijering J.P.P., den Boer M.L., Pieters R. Molecular determinants of glucocorticoid sensitivity and resistance in acute lymphoblastic leukemia. Leukemia. 17:2003;17-25
    • (2003) Leukemia , vol.17 , pp. 17-25
    • Tissing, W.J.E.1    Meijering, J.P.P.2    Den Boer, M.L.3    Pieters, R.4
  • 37
    • 0034845924 scopus 로고    scopus 로고
    • Characterisation of two novel mutations in the glucocorticoid receptor gene in patients with primary cortisol resistance
    • Ruiz M., Lind U., Gavfels M., Eggerston G. Characterisation of two novel mutations in the glucocorticoid receptor gene in patients with primary cortisol resistance. Clin Endocrinol. 55:2001;363-371
    • (2001) Clin Endocrinol , vol.55 , pp. 363-371
    • Ruiz, M.1    Lind, U.2    Gavfels, M.3    Eggerston, G.4
  • 38
    • 0026026319 scopus 로고
    • Point mutation causing a single amino acid substitution in the hormone binding domain of the glucocorticoid receptor in familial glucocorticoid resistance
    • Hurley D.M., Accili D., Stratakis C.A. Point mutation causing a single amino acid substitution in the hormone binding domain of the glucocorticoid receptor in familial glucocorticoid resistance. J Clin Invest. 87:1991;680-686
    • (1991) J Clin Invest , vol.87 , pp. 680-686
    • Hurley, D.M.1    Accili, D.2    Stratakis, C.A.3
  • 39
    • 0027217319 scopus 로고
    • A mutation of the glucocorticoid receptor in primary cortisol resistance
    • Malchoff D.M., Brufsky A., Reardon G. A mutation of the glucocorticoid receptor in primary cortisol resistance. J Clin Invest. 91:1993;1918-1925
    • (1993) J Clin Invest , vol.91 , pp. 1918-1925
    • Malchoff, D.M.1    Brufsky, A.2    Reardon, G.3
  • 40
    • 15144360854 scopus 로고    scopus 로고
    • A polymorphism in the glucocorticoid receptor gene may be associated with an increased sensitivity to glucocorticoids in vivo
    • Huizenga N.A., Koper J.W., de Lange P. A polymorphism in the glucocorticoid receptor gene may be associated with an increased sensitivity to glucocorticoids in vivo. J Clin Endocrinol Metab. 83:1998;144-151
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 144-151
    • Huizenga, N.A.1    Koper, J.W.2    De Lange, P.3
  • 41
    • 0028472787 scopus 로고
    • Chemical mutational analysis of the human glucocorticoid receptor cDNA in glucocorticoid resistant bronchial asthma
    • Lane S.J., Arm J.P., Staynov D.Z., Lee T.H. Chemical mutational analysis of the human glucocorticoid receptor cDNA in glucocorticoid resistant bronchial asthma. Hum Genet. 11:1994;42-48
    • (1994) Hum Genet , vol.11 , pp. 42-48
    • Lane, S.J.1    Arm, J.P.2    Staynov, D.Z.3    Lee, T.H.4
  • 42
    • 0033821409 scopus 로고    scopus 로고
    • Glucocorticoid receptor recruitment of histone deacetylase 2 inhibits interleukin-1β-induced histone H4 acetylation on lysines 8 and 12
    • Ito K., Barnes P.J., Adcock I.M. Glucocorticoid receptor recruitment of histone deacetylase 2 inhibits interleukin-1β-induced histone H4 acetylation on lysines 8 and 12. Mol Cell Biol. 20:2000;6891-6903
    • (2000) Mol Cell Biol , vol.20 , pp. 6891-6903
    • Ito, K.1    Barnes, P.J.2    Adcock, I.M.3
  • 43
    • 0037458439 scopus 로고    scopus 로고
    • Molecular mechanisms of corticosteroid actions in chronic inflammatory airway diseases
    • Pelaia G., Vatrella A., Cuda G., Maselli R., Marsico S.A. Molecular mechanisms of corticosteroid actions in chronic inflammatory airway diseases. Life Sci. 72:2003;1549-1561
    • (2003) Life Sci , vol.72 , pp. 1549-1561
    • Pelaia, G.1    Vatrella, A.2    Cuda, G.3    Maselli, R.4    Marsico, S.A.5
  • 48
    • 0036168725 scopus 로고    scopus 로고
    • Cytokine modulators as novel therapies for asthma
    • Barnes P.J. Cytokine modulators as novel therapies for asthma. Annu Rev Pharmacol Toxicol. 42:2002;81-98
    • (2002) Annu Rev Pharmacol Toxicol , vol.42 , pp. 81-98
    • Barnes, P.J.1
  • 50
    • 0036231010 scopus 로고    scopus 로고
    • P38 mitogen-activated protein kinase-induced glucocorticoid receptor phosphorylation reduces its activity: Role in steroid-insensitive asthma
    • Irusen E., Matthews J.G., Takahashi A., Barnes P.J., Chung K.F., Adcock I.M. p38 mitogen-activated protein kinase-induced glucocorticoid receptor phosphorylation reduces its activity: role in steroid-insensitive asthma. J Allergy Clin Immunol. 109:2002;649-657
    • (2002) J Allergy Clin Immunol , vol.109 , pp. 649-657
    • Irusen, E.1    Matthews, J.G.2    Takahashi, A.3    Barnes, P.J.4    Chung, K.F.5    Adcock, I.M.6
  • 51
    • 0032478254 scopus 로고    scopus 로고
    • Antagonism of glucocorticoid receptor transcriptional activation by the c-Jun N-terminal kinase
    • Rogatsky I., Logan S.K., Garabedian M.J. Antagonism of glucocorticoid receptor transcriptional activation by the c-Jun N-terminal kinase. Proc Natl Acad Sci USA. 95:1998;2050-2055
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 2050-2055
    • Rogatsky, I.1    Logan, S.K.2    Garabedian, M.J.3
  • 53
    • 0027521592 scopus 로고
    • Nuclear receptor/AP-1 interaction
    • Pfahl M. Nuclear receptor/AP-1 interaction. Endocrinol Rev. 14:1993;651-658
    • (1993) Endocrinol Rev , vol.14 , pp. 651-658
    • Pfahl, M.1
  • 54
    • 0028107237 scopus 로고
    • Physical association and functional antagonism between the p65 subunit of transcription factor NF-κB and the glucocorticoid receptor
    • Ray A., Prefontaine K.E. Physical association and functional antagonism between the p65 subunit of transcription factor NF-κB and the glucocorticoid receptor. Proc Natl Acad Sci USA. 91:1994;752-756
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 752-756
    • Ray, A.1    Prefontaine, K.E.2
  • 55
    • 0031842804 scopus 로고    scopus 로고
    • Transcription factors and asthma
    • Barnes P.J., Adcock I.M. Transcription factors and asthma. Eur Respir J. 12:1998;221-234
    • (1998) Eur Respir J , vol.12 , pp. 221-234
    • Barnes, P.J.1    Adcock, I.M.2
  • 56
    • 0029741438 scopus 로고    scopus 로고
    • Steroid resistance in asthma: Molecular mechanisms
    • Adcock I.M. Steroid resistance in asthma: molecular mechanisms. Am J Respir Crit Care Med. 154:1996;S58-S61
    • (1996) Am J Respir Crit Care Med , vol.154
    • Adcock, I.M.1
  • 57
    • 0032535369 scopus 로고    scopus 로고
    • Corticosteroid-resistant bronchial asthma is associated with increased c-fos expression in monocytes and T lymphocytes
    • Lane S.J., Adcock I.M., Richards D., Hawrylowicz C., Barnes P.J., Lee T.H. Corticosteroid-resistant bronchial asthma is associated with increased c-fos expression in monocytes and T lymphocytes. J Clin Invest. 102:1998;2156-2164
    • (1998) J Clin Invest , vol.102 , pp. 2156-2164
    • Lane, S.J.1    Adcock, I.M.2    Richards, D.3    Hawrylowicz, C.4    Barnes, P.J.5    Lee, T.H.6
  • 58
    • 17044446216 scopus 로고    scopus 로고
    • Novel single nucleotide polymorphisms (SNPs) at positions 497 (T/G)Q and 829 (T/C) in the human c-fos gene and haplotype association
    • Umino Y., Hohjoh H., Tokunaga K. Novel single nucleotide polymorphisms (SNPs) at positions 497 (T/G)Q and 829 (T/C) in the human c-fos gene and haplotype association. Hum Mutat. 16:2000;279
    • (2000) Hum Mutat , vol.16 , pp. 279
    • Umino, Y.1    Hohjoh, H.2    Tokunaga, K.3
  • 59
    • 0036772346 scopus 로고    scopus 로고
    • Pharmacogenetics of treatment with leukotriene modifiers
    • Wechsler M.E., Israel E. Pharmacogenetics of treatment with leukotriene modifiers. Curr Opin Allergy Clin Immunol. 2:2002;395-401
    • (2002) Curr Opin Allergy Clin Immunol , vol.2 , pp. 395-401
    • Wechsler, M.E.1    Israel, E.2
  • 60
    • 0031003816 scopus 로고    scopus 로고
    • Naturally occurring mutations in the human 5-lipoxygenase gene promoter which modify transcription factor binding and reporter gene transcription
    • In K.H., Asano K., Bejer D., Grobholz J. Naturally occurring mutations in the human 5-lipoxygenase gene promoter which modify transcription factor binding and reporter gene transcription. J Clin Invest. 99:1997;1130-1137
    • (1997) J Clin Invest , vol.99 , pp. 1130-1137
    • In, K.H.1    Asano, K.2    Bejer, D.3    Grobholz, J.4
  • 64
    • 0031590522 scopus 로고    scopus 로고
    • 4 synthase promoter polymorphism and risk of aspirin induced asthma
    • 4 synthase promoter polymorphism and risk of aspirin induced asthma. Lancet. 350:1997;1599-1600
    • (1997) Lancet , vol.350 , pp. 1599-1600
    • Sanak, M.1    Simon, H.-U.2    Szczeklik, A.3
  • 65
    • 0032519008 scopus 로고    scopus 로고
    • 4 synthase in bronchial biopsies from patients with aspirin-intolerant asthma
    • 4 synthase in bronchial biopsies from patients with aspirin-intolerant asthma. J Clin Invest. 101:1998;834-846
    • (1998) J Clin Invest , vol.101 , pp. 834-846
    • Cowburn, A.S.1    Sladek, K.2    Soja, J.3
  • 70
    • 0033052113 scopus 로고    scopus 로고
    • Recent advances in our understanding of the use of theophylline in the treatment of asthma
    • Page C.P. Recent advances in our understanding of the use of theophylline in the treatment of asthma. J Clin Pharmacol. 39:1999;237-240
    • (1999) J Clin Pharmacol , vol.39 , pp. 237-240
    • Page, C.P.1
  • 71
    • 0031914520 scopus 로고    scopus 로고
    • Phosphodiesterase isozymes: Molecular targets for novel antiasthma agents
    • Torphy T.J. Phosphodiesterase isozymes: molecular targets for novel antiasthma agents. Am J Respir Crit Care Med. 157:1998;351-370
    • (1998) Am J Respir Crit Care Med , vol.157 , pp. 351-370
    • Torphy, T.J.1
  • 72
    • 0037173056 scopus 로고    scopus 로고
    • A molecular mechanism of action of theophylline: Induction of histone deacetylase activity to decrease inflammatory gene expression
    • Ito K., Lim S., Caramori G., Cosio B., Chung K.F., Adcock I.M., Barnes P.J. A molecular mechanism of action of theophylline: induction of histone deacetylase activity to decrease inflammatory gene expression. Proc Natl Acad Sci USA. 2002;8921-8926
    • (2002) Proc Natl Acad Sci USA , pp. 8921-8926
    • Ito, K.1    Lim, S.2    Caramori, G.3    Cosio, B.4    Chung, K.F.5    Adcock, I.M.6    Barnes, P.J.7
  • 76
    • 0030783057 scopus 로고    scopus 로고
    • Hepatic microsomal metabolism of montelukast, a potent leukotriene D4 receptor antagonist, in humans
    • Chiba M., Xu X., Nishime J.A., Balani S.K., Lin J.H. Hepatic microsomal metabolism of montelukast, a potent leukotriene D4 receptor antagonist, in humans. Drug Metab Dispos. 25:1997;1022-1031
    • (1997) Drug Metab Dispos , vol.25 , pp. 1022-1031
    • Chiba, M.1    Xu, X.2    Nishime, J.A.3    Balani, S.K.4    Lin, J.H.5
  • 77
    • 0029018483 scopus 로고
    • Characterisation of the human cytochromes p450 involved in theophylline 8-hydroxylation
    • Zhang Z.Y., Kaminsky L.S. Characterisation of the human cytochromes p450 involved in theophylline 8-hydroxylation. Biochem Pharmacol. 50:1995;205-211
    • (1995) Biochem Pharmacol , vol.50 , pp. 205-211
    • Zhang, Z.Y.1    Kaminsky, L.S.2
  • 78
    • 0028878830 scopus 로고
    • Budesonide is metabolised by cytochrome P450 3A (CYP3A) enzymes in human liver
    • Johnsson G., Astrom A., Andersson P. Budesonide is metabolised by cytochrome P450 3A (CYP3A) enzymes in human liver. Drug Metab Dispos. 23:1995;137-142
    • (1995) Drug Metab Dispos , vol.23 , pp. 137-142
    • Johnsson, G.1    Astrom, A.2    Andersson, P.3
  • 79
    • 0029960236 scopus 로고    scopus 로고
    • The aliphatic oxidation of salmeterol to alpha-hydroxysalmeterol in human liver microsome is catalysed by CYP3A
    • Manchee G.R., Eddershaw P.J., Ranshaw L.E. The aliphatic oxidation of salmeterol to alpha-hydroxysalmeterol in human liver microsome is catalysed by CYP3A. Drug Metab Dispos. 24:1996;555-559
    • (1996) Drug Metab Dispos , vol.24 , pp. 555-559
    • Manchee, G.R.1    Eddershaw, P.J.2    Ranshaw, L.E.3
  • 80
    • 0031840217 scopus 로고    scopus 로고
    • Genetic polymorphism of cytochrome p450s, CYP2C19, and CYP2C9 in a Japanese population
    • Kimura M., Ieiri I., Mamiya K., Urae A., Higuchi S. Genetic polymorphism of cytochrome p450s, CYP2C19, and CYP2C9 in a Japanese population. Ther Drug Monit. 20:1998;243-247
    • (1998) Ther Drug Monit , vol.20 , pp. 243-247
    • Kimura, M.1    Ieiri, I.2    Mamiya, K.3    Urae, A.4    Higuchi, S.5
  • 81
    • 0034041373 scopus 로고    scopus 로고
    • Catalytic activity of three variants (Ile, Leu, and Thr) at amino acid residue 359 in human CYP2C9 gene and simultaneous detection using single strand conformational polymorphism analysis
    • Ieiri I., Tainaka H., Morita T. Catalytic activity of three variants (Ile, Leu, and Thr) at amino acid residue 359 in human CYP2C9 gene and simultaneous detection using single strand conformational polymorphism analysis. Ther Drug Monit. 22:2000;237-244
    • (2000) Ther Drug Monit , vol.22 , pp. 237-244
    • Ieiri, I.1    Tainaka, H.2    Morita, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.