Protection of human cerebral neurons from neurodegenerative insults by gene delivery of soluble tumor necrosis factor p75 receptor

Experimental Brain Research

Volumn 165, Issue 3, 2005, Pages 383-391

  Williams, Marc Adrian ^a,b   Turchan, Jadwiga ^a   Lu, Yang ^a   Nath, Avindra ^a   Drachman, Daniel B ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS ASTHMA AND ALLERGY CENTER   (United States)

Author keywords

Adenovirus; Apoptosis; Gene therapy; Neurodegeneration; Neuron; p75TNFR; TNF

Indexed keywords

ADENOVIRUS VECTOR; BETA GALACTOSIDASE; DACTINOMYCIN; DIMER; DIMERIC PROTEIN P75 TUMOR NECROSIS FACTOR RECEPTOR; GLYCOPROTEIN GP 120; PROTEIN P75; RECEPTOR; TRANSACTIVATOR PROTEIN; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR; UNCLASSIFIED DRUG; VIRUS PROTEIN;

APOPTOSIS; ARTICLE; BINDING AFFINITY; BRAIN NERVE CELL; EXPOSURE; FETUS; GENE EXPRESSION; GENE TARGETING; GENE THERAPY; GENETIC TRANSDUCTION; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN TISSUE; IN VITRO STUDY; NERVE CELL; NERVE CELL NECROSIS; NERVE DEGENERATION; NEUROPROTECTION; NEUROTOXICITY; PRIORITY JOURNAL; PROTEIN DOMAIN; RECEPTOR BINDING;

ADENOVIRIDAE; BRAIN; CELL DEATH; CELLS, CULTURED; FETUS; FLOW CYTOMETRY; GENE PRODUCTS, TAT; GENE THERAPY; GENETIC VECTORS; HIV ENVELOPE PROTEIN GP120; HUMANS; NEURODEGENERATIVE DISEASES; NEURONS; NEUROTOXINS; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE II; TRANSDUCTION, GENETIC; TUMOR NECROSIS FACTOR-ALPHA;

EID: 23944449575     PISSN: 00144819     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00221-005-2307-9     Document Type: Article

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