HIV-1 Tat induces neuronal death via tumor necrosis factor-α and activation of non-N-methyl-D-aspartate receptors by a NFκB-independent mechanism

Journal of Biological Chemistry

Volumn 273, Issue 28, 1998, Pages 17852-17858

  New, Deborah R ^a,b   Maggirwar, Sanjay B ^a   Epstein, Leon G ^a   Dewhurst, Stephen ^a   Gelbard, Harris A ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^b UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUTAMATE RECEPTOR; TRANSACTIVATOR PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; MACROPHAGE ACTIVATION; NERVE CELL NECROSIS; NEUROPATHOLOGY; NEUROTOXICITY; PRIORITY JOURNAL; VIRUS PATHOGENESIS;

ANIMALS; APOPTOSIS; BASE SEQUENCE; CELLS, CULTURED; DNA PROBES; GENE PRODUCTS, TAT; HIV-1; HUMANS; NEURONS; NF-KAPPA B; OXIDATIVE STRESS; RATS; RECEPTORS, N-METHYL-D-ASPARTATE; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED; TUMOR NECROSIS FACTOR-ALPHA;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; RNA VIRUSES;

EID: 0032504151     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.28.17852     Document Type: Article

References (45)

1. Epstein, L. G., and Gendelman, H. E. (1993) Ann. Neurol. 33, 429-436
2. Gelbard, H. A., and Epstein, L. G. (1995) Curr. Opin. Pediatr. 7, 655-662
3. Lipton, S. A., Sucher, N. J., Kaiser, P. K., and Dreyer, E. B. (1991) Neuron 7, 111-118
4. Lipton, S. A. (1992) Neuroreport 3, 913-915
5. Frankel, A. D., and Pabo, C. O. (1988) Cell 55, 1189-1193
6. Ma, M., and Nath, A. (1997) J. Virol. 71, 2495-2499
7. Nath, A., Psooy, K., Martin, C., Knudsen, B., Magnuson, D. S. K., Haughey, D., and Geiger, J. D. (1996) J. Virol. 70, 1475-1480
8. New, D. R., Ma, M., Epstein, L. G., Nath, A., and Gelbard, H. A. (1997) J. Neurovirol. 3, 168-173
9. Magnuson, D. S. K., Knudsen, B. E., Geiger, J. D., Brownstone, R. M., and Nath, A. (1995) Ann. Neurol. 37, 373-380
10. Philippon, V., Vellutini, C., Gambarelli, D., Harkiss, G., Arbuthnott, G., Metzger, D., Roubin, R., and Filippi, P. (1994) Virology 205, 519-529
11. Gelbard, H. A., Dzenko, K., DiLoreto, D., del Cerro, C., del Cerro, M., and Epstein, L. G. (1993) Dev. Neurosci. 15, 417-422
12. Talley, A., Dewhurst, S., Perry, S., Gummuluru, S., Dollard, S. C., Fine, S. M., New, D., Epstein, L. G., Gendelman, H. E., and Gelbard, H. A. (1995) Mol. Cell. Biol. 15, 2359-2366
13. Gelbard, H. A., Nottet, H. S. L. M., Swindells, S., Jett, M., Dzenko, K. A., Genis, P., White, R., Wang, L., Choi, Y.-B., Zhang, D., Lipton, S. A., Tourtellotte, W. W., Epstein, L. G., and Gendelman, H. E. (1994) J. Virol. 68, 4628-4635
14. Biedler, J. L., Helson, L., and Spengler, B. A. (1973) Cancer Res. 33, 2643-2652
15. Hatten, M. E. (1985) J. Cell Biol. 100, 384-396
16. White, L. A., Eaton, M. J., Castro, M. C., Klose, K. J., Globus, M., Y.-T., Shaw, G., and Whittemore, S. R. (1994) J. Neurosci. 14, 6744-6753
17. Kawamoto, J. C., and Barret, J. N. (1986) Brain Res. 384, 84-93
18. Maggirwar, S. B., Harhaj, E. W., and Sun, S.-C. (1997) Mol. Cell. Biol. 17, 2605-2614
19. Munoz, E., Courtois, G., Veschambre, P., Jalinot, P., and Israel, A. (1994) J. Virol. 68, 8035-8044
20. Schreiber, E., Matthias, P., Muller, M. M., and Schaffner, W. (1989) Nucleic Acids Res. 17, 6419
21. Chen, P., Mayne, M., Power, C., and Nath, A. (1997) J. Biol. Chem. 272, 22385-22388
22. Elliott, M. J., Maini, R. N., Feldmann, M., Kalden, J. R., Antoni, C., Smolen, J. S., Leeb, B., Breedveld, F. C., MacFarlane, J. D., Bijl, H., and Woody, J. N. (1994) Lancet 344, 1105-1108
23. Cheng, B., Christakos, S., and Mattson, M. P. (1994) Neuron 12, 139-153
24. Zauli, G., Gibellini, D., Milani, D., Mazzoni, M., Borgatti, P., La Placa, M., and Capitani, S. (1993) Cancer Res. 53, 4481-4485
25. Malinin, N. L., Boldin, M. P., Kovalenko, A. V., and Wallach, D. (1997) Nature 385, 540-544
26. Song, H. Y., Regnier, C. H., Kirschning, C. J., Goeddel, D. V., Rothe, M. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 9792-9796
27. Mercurio, F., Zhu, H., Murray, B. W., Shevchenko, A., Bennett, B. L., Li, J. W., Young, D. B., Barbosa, M., Man, M., Manning, A., and Rao, A. (1997) Science 278, 860-866
28. Woronicz, J. D., Gao, X., Cao, Z., Rothe, M., and Goeddel, D. V. (1997) Science 278, 866-869
29. Regnier, C. H., Song, H. Y., Gao, X., Goeddel, D. V., Cao, Z., and Rothe, M. (1997) Cell 90, 373-383
30. DiDonato, J. A., Hayakawa, M., Rothwarf, D. M., Zandi, E., and Karin, M. (1997) Nature 388, 548-519
31. Zandi, E., Rothwarf, D. M., Delhase, M., Hayakawa, M., and Karin, M. (1997) Cell 91, 243-252
32. Thanos D., and Maniatis, T. (1995) Cell 80, 529-532
33. Verma, I. M., Stevenson, J. K., Schwarz, E. M., Van Antwerp, D., Miyamoto, S. (1995) Genes Dev. 9, 2723-2735
34. Li, C. J., Friedman, D. J., Wang, C., Metelev, V., and Pardee, A. B. (1995) Science 268, 429-431
35. Purvis, S. F., Jacobberger, J. W., Sramkoski, R. M., Patki, A. H., and Lederman, M. M. (1995) AIDS Res. Hum. Retro. 11, 443-450
36. Westendorp, M. O., Frank, R., Ochsenbauer, C., Stricker, K., Dhein, J., Walczak, H., Debatin, K.-M., and Krammer, P. H. (1995) Nature 375, 497-500
37. Westendorp, M. O., Shatrov, V. A., Schulze-Osthoff, K., Frank, R., Kraft, M., Los, M., Krammer, P. H., Droge, W., and Lehmann, V. (1995) EMBO J. 14, 546-554
38. Hsu, H., Shu, H.-B., Pan, M.-G., and Goeddel, D. V. (1996) Cell 84, 299-308
39. Swantek, J. L., Cobb, M. H., and Geppert, T. D. (1997) Mol. Cell. Biol. 17, 6274-6282
40. Han, J., Brown, T., and Beutler, B. (1990) J. Exp. Med. 171, 465-475
41. Shakhov, A. N., Collart, M. A., Vassalli, P., Nedospasov, S. A., and Jongeneel, C. V. (1990) J. Exp. Med. 171, 35-47
42. Perry, S. W., Epstein, L. G., and Gelbard, H. A. (1997) Biotechniques 22, 1020-1023
43. Perry, S. W., Epstein, L. G., and Gelbard, H. A. (1997) Biotechniques 22, 1102-1106
44. Everall, I. P., Hudson, L., Al-Sarraj, S., Honavar, M., Lantos, P., and Kerwin, R. (1995) Nature Med. 1, 1174-1178
45. Flores, S. C., Marecki, J. C., Harper, K. P., Bose, S. K., Nelson, S. K., and McCord, J. M. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 7632-7636