Characterization of recombinant Eschericha coli 5'-Methylthioadenosine/S-Adenosylhomocysteine nucleosidase: Analysis of enzymatic activity and substrate specificity

Biochemical and Biophysical Research Communications

Volumn 228, Issue 3, 1996, Pages 724-732

  Cornell, Kenneth A ^a,b,c   Swarts, William E ^c   Barry, Ronald D ^c   Riscoe, Michael K ^a,b,c  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^c PORTLAND VA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5' METHYLTHIOADENOSINE; ADENOSINE; ENZYME INHIBITOR; NUCLEOSIDASE; RECOMBINANT PROTEIN;

ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME SPECIFICITY; ESCHERICHIA COLI; GENETIC ENGINEERING; NONHUMAN; PH; PRIORITY JOURNAL; TEMPERATURE;

ESCHERICHIA COLI;

EID: 0030597298     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.1996.1723     Document Type: Article

References (43)

1. 1. Travis, J. (1994) Science 264, 360-362.
2. 2. Davies, J. (1994) Science 264, 375-382.
3. 3. Tabor, H., Tabor, C., and Rosenthal, S. (1961) Ann. Rev. Biochem. 30, 579-604.
4. 4. Cantoni, G. (1975) Ann. Rev. Biochem. 44, 435-451.
5. 5. Borchardt, R. T. (1980) J. Med. Chem. 23, 347-357.
6. 6. Pajula, R. L., and Raina, A. (1979) FEBS Lett. 99, 343-345.
7. 7. Raina, A., Tuomi, K., and Pajula, R. L. (1982) Biochem. J. 204, 697-703.
8. 8. Riscoe, M. K., Tower, P. A., and Ferro, A. J. (1984) Biochem. Pharmacol. 33, 3639-3643.
9. 9. Cerri, M. A., Beltran-Nunez, A., Bernasconi, S., Dejana, E., Bassi, L., and Bazzoni, G. (1993) Eur. J. Pharm. 232, 291-294.
10. 10. Pegg, A. E., and Williams-Ashman, H. G. (1969) Biochem. J. 115, 241-247.
11. 11. Kamatani, N., and Carson, D. A. (1981) Biochim. Biophys. Acta 675, 344-350.
12. 12. Kamatani, N., Kubota, M., Willis, E. H., Frincke, L. A., and Carson, D. A. (1984) Adv. Exp. Med. Biol. 83-88.
13. 13. Backlund, P. S. J., and Smith, R. A. (1981) J. Biol. Chem. 256, 1533-1535.
14. 14. Backlund, P. J., and Smith, R. A. (1982) Biochem. Biophys. Res. Commun. 108, 687-695.
15. 15. de la Haba, G., and Cantoni, G. L. (1959) J. Biol. Chem. 234, 603-608.
16. 16. Duerre, J. A. (1962) J. Biol. Chem. 237, 3737-3741.
17. 17. Shimizu, S., Abe, T., and Yamada, H. (1988) FEMS Letters 51, 177-180.
18. 18. Ferro, A. J., Barrett, A., and Shapiro, S. K. (1976) Biochim. Biophys. Acta 438, 487-494.
19. 19. Guranowski, A. B., Chiang, P. K., and Cantoni, G. L. (1981) Eur. J. Biochem. 114, 293-299.
20. 20. Kushad, M. M., Richardson, D. G., and Ferro, A. J. (1985) Plant Physiol. 79, 525-529.
21. 21. Della-Ragione, F., Porcelli, M., Cartenì-Farina, M., Zappia, V., and Pegg, A. E. (1985) Biochem. J. 232, 335-341.
22. 22. Cornell, K. A., Winter, R. W., Tower, P. A., and Riscoe, M. K. (1996) Biochem. J. 317, 285-290.
23. 23. Zappia, V., Della Ragione, F., and Cartenì-Farina, M. (1985) in Biological Methylation and Drug Design: Experimental and Clinical Roles of S-Adenosylmethionine (Borchardt, R., Creveling, C., and Ueland, P., Eds.), pp. 287-300. The Humana Press Inc., Clifton, New Jersey.
24. 24. Zappia, V., Della Ragione, F., Pontoni, G., Gragnaniello, V., and Cartenì-Farina, M. (1988) Adv. Exp. Med. Biol. 250, 165-177.
25. 25. Cornell, K. A., and Riscoe, M. K. (1996) J. Biol. Chem. submitted.
26. 26. Schlenk, F. (1983) Adv. Enzymol. 54, 195-265.
27. 27. Lineweaver, H., Burke, D., and Deming, W. (1934) J. Am. Chem. Soc. 56, 225-230.
28. 28. Cornish-Bowden, A. (1995) in Analysis of Enzyme Kinetic Data, Oxford University Press, Oxford.
29. 29. Ausubel, F., Brent, R., Kingston, R., Moore, D., Seidman, J., Smith, J., and Struhl, K. (1992) in Short Protocols in Molecular Biology, John Wiley and Sons, New York.
30. 30. Laemmli, U. K. (1970) Nature 227, 680-685.
31. 31. Towbin, H., Staehelin, T., and Gordon, J. (1979) Proc. Natl. Acad. Sci. USA 76, 4350-4354.
32. 32. Cornell, K. A. (1997) Doctoral thesis, Department of Biochemistry and Molecular Biology, Oregon Health Sciences University, Portland, Oregon.
33. 33. Silverman, R. B. (1992) in The Organic Chemistry of Drug Design and Drug Action, pp. 4-51, Academic Press, Inc., San Diego.
34. 34. Garrett, E. R., and Mehta, P. J. (1972) J. Am. Chem. Soc. 94, 8532-8541.
35. 35. Mentch, F., Parkin, D. W., and Schramm, V. L. (1987) Biochemistry 26, 921-930.
36. 36. Savarese, T. M., Chu, S. H., Chu, M. Y., and Parks, R. J. (1985) Biochem. Pharmacol. 34, 361-367.
37. 37. Fitchen, J. H., Riscoe, M. K., and Ferro, A. J. (1988) Adv. Exp. Med. Biol. 250, 199-210.
38. 38. Riscoe, M. K., Ferro, A. J., and Fitchen, J. H. (1988) Antimicrob. Agents Chemother. 32, 1904-1906.
39. 39. Gianotti, A. J., Tower, P. A., Sheley, J. H., Conte, P. A., Spiro, C., Ferro, A. J., Fitchen, J. H., and Riscoe, M. K. (1990) J. Biol. Chem. 265, 831-837.
40. 40. Tower, P., Johnson, L., Ferro, A., Fitchen, J., and Riscoe, M. (1991) Antimicrob. Agents Chemother. 35, 1557-1561.
41. 41. Winter, R., Cornell, K., Johnson, L., and Riscoe, M. (1993) Bioorg. & Med. Chem. Lett. 3, 2079-2082.
42. 42. Olopade, O., Pomykala, H., Hagos, F., Sveen, L., Espinosa, R., III, Dreyling, M., Gursky, S., Stadler, W., Le Beau, M., and Bohlander, S. (1995) Proc. Natl. Acad. Sci., USA 92, 6489-6493.
43. 43. Nobori, T., Takabayashi, K., Tran, P., Orvis, L., Batova, A., Yu, A. L., and Carson, D. (1996) Proc. Natl. Acad.f Sci., USA 93, 6203-6208.