메뉴 건너뛰기




Volumn 164, Issue 1, 2000, Pages 371-378

IL-4 and IL-10 antagonize IL-12-mediated protection against acute vaccinia virus infection with a limited role of IFN-γ and nitric oxide synthetase 2

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 1; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 4; INTERLEUKIN 6; NITRIC OXIDE; NITRIC OXIDE SYNTHASE;

EID: 0033964865     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.164.1.371     Document Type: Article
Times cited : (119)

References (89)
  • 2
    • 0029847368 scopus 로고    scopus 로고
    • Functional diversity of helper T lymphocytes
    • Abbas, A. K., K. M. Murphy, and A. Sher. 1997. Functional diversity of helper T lymphocytes. Nature 383:787.
    • (1997) Nature , vol.383 , pp. 787
    • Abbas, A.K.1    Murphy, K.M.2    Sher, A.3
  • 3
    • 0030024279 scopus 로고    scopus 로고
    • Immunology taught by viruses
    • Zinkernagel, R. M. 1996. Immunology taught by viruses. Science 271:173.
    • (1996) Science , vol.271 , pp. 173
    • Zinkernagel, R.M.1
  • 4
    • 0027465066 scopus 로고
    • A case for cytokines as effector molecules in the resolution of virus infection
    • Ramsay, A. J., J. Ruby, and I. A. Ramshaw. 1993. A case for cytokines as effector molecules in the resolution of virus infection. Immunol. Today 14:155.
    • (1993) Immunol. Today , vol.14 , pp. 155
    • Ramsay, A.J.1    Ruby, J.2    Ramshaw, I.A.3
  • 5
    • 0018234247 scopus 로고
    • Different rules govern help for cytotoxic T cells and B cells
    • Bennink, J. R., and P. C. Doherty. 1978. Different rules govern help for cytotoxic T cells and B cells. Nature 276:829.
    • (1978) Nature , vol.276 , pp. 829
    • Bennink, J.R.1    Doherty, P.C.2
  • 6
    • 0017884694 scopus 로고
    • The lymphoreticular system in triggering virus plus self-specific cytotoxic T cells: Evidence for T help
    • Zinkernagel, R. M., G. N. Callahan, A. Althage, S. Cooper, J. W. Streilein, and J. Klein. 1978. The lymphoreticular system in triggering virus plus self-specific cytotoxic T cells: evidence for T help. J. Exp. Med. 147-897.
    • (1978) J. Exp. Med. , pp. 147-897
    • Zinkernagel, R.M.1    Callahan, G.N.2    Althage, A.3    Cooper, S.4    Streilein, J.W.5    Klein, J.6
  • 7
    • 0028918570 scopus 로고
    • + Th1 clones with both cytotoxic and helper activity mediate protective humoral immunity against a lethal poliovirus infection in transgenic mice expressing the human poliovirus receptor
    • + Th1 clones with both cytotoxic and helper activity mediate protective humoral immunity against a lethal poliovirus infection in transgenic mice expressing the human poliovirus receptor. J. Exp. Med. 181:1285.
    • (1995) J. Exp. Med. , vol.181 , pp. 1285
    • Mahon, B.P.1    Katrak, K.2    Nomoto, A.3    Macadam, A.J.4    Minor, P.D.5    Mills, K.H.6
  • 10
    • 0027957155 scopus 로고
    • Late phase inhibition of murine cytomegalovirus replication by synergistic action of interferon-γ and tumour necrosis factor
    • Lucin, P., S. Jonjic, M. Messerle, B. Polic, H. Hengel, and U. Koszinowski. 1994. Late phase inhibition of murine cytomegalovirus replication by synergistic action of interferon-γ and tumour necrosis factor. J. Gen. Virol. 75:101.
    • (1994) J. Gen. Virol. , vol.75 , pp. 101
    • Lucin, P.1    Jonjic, S.2    Messerle, M.3    Polic, B.4    Hengel, H.5    Koszinowski, U.6
  • 12
    • 0027941401 scopus 로고
    • + T helper type 2 T lymphocytes do not promote recovery from experimental virus infection
    • + T helper type 2 T lymphocytes do not promote recovery from experimental virus infection. J. Exp. Med. 180:1273.
    • (1994) J. Exp. Med. , vol.180 , pp. 1273
    • Graham, M.B.1    Braciale, V.L.2    Braciale, T.J.3
  • 13
    • 0030954837 scopus 로고    scopus 로고
    • Measles virus suppresses cell-mediated immunity by interfering with the survival and functions of dendritic and T cells
    • Fugier-Vivier, I., C. Servet-Delprat, P. Rivailler, M. C. Rissoan, Y. J. Liu, and C. Rabourdin-Combe. 1997. Measles virus suppresses cell-mediated immunity by interfering with the survival and functions of dendritic and T cells. J. Exp. Med. 186:813.
    • (1997) J. Exp. Med. , vol.186 , pp. 813
    • Fugier-Vivier, I.1    Servet-Delprat, C.2    Rivailler, P.3    Rissoan, M.C.4    Liu, Y.J.5    Rabourdin-Combe, C.6
  • 14
    • 0029818545 scopus 로고    scopus 로고
    • Mechanism of suppression of cell-mediated immunity by measles virus
    • Published erratum appears in 1997 Science 275·1053.
    • Karp, C. L., M. Wysocka, L. M. Wahl, J. M. Ahearn, P. J. Cuomo, B. Sherry, G. Trinchieri, and D. E. Griflin. 1996. Mechanism of suppression of cell-mediated immunity by measles virus. [Published erratum appears in 1997 Science 275·1053.] Science 273:228.
    • (1996) Science , vol.273 , pp. 228
    • Karp, C.L.1    Wysocka, M.2    Wahl, L.M.3    Ahearn, J.M.4    Cuomo, P.J.5    Sherry, B.6    Trinchieri, G.7    Griflin, D.E.8
  • 15
    • 0027340164 scopus 로고
    • A TH1→TH2 switch is a critical step in the etiology of HIV infection
    • Clerici, M., and G. M. Shearer. 1993. A TH1→TH2 switch is a critical step in the etiology of HIV infection. Immunol. Today 14:107.
    • (1993) Immunol. Today , vol.14 , pp. 107
    • Clerici, M.1    Shearer, G.M.2
  • 16
    • 0028972480 scopus 로고
    • + cell response against human immunodeficiency virus: Implications lor long-term survival
    • + cell response against human immunodeficiency virus: implications lor long-term survival. Proc. Natl. Acad. Sci. USA 92:11135.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 11135
    • Barker, E.1    Mackewicz, C.E.2    Levy, J.A.3
  • 18
    • 0028786927 scopus 로고
    • The in vivo antiviral activity of interleukin-12 is mediated by γ interferon
    • Ozmen, L., M. Aguet, G. Trinchieri, and G. Garotta. 1995. The in vivo antiviral activity of interleukin-12 is mediated by γ interferon. J. Virol. 69:8147.
    • (1995) J. Virol. , vol.69 , pp. 8147
    • Ozmen, L.1    Aguet, M.2    Trinchieri, G.3    Garotta, G.4
  • 19
    • 0029096181 scopus 로고
    • Requirement for natural killer cell-produced interferon γ in defense against murine cytomegalovirus infection and enhancement of this defense pathway by interleukin 12 administration
    • Orange, J. S., B. Wang, C. Terhorst, and C. A. Biron. 1995. Requirement for natural killer cell-produced interferon γ in defense against murine cytomegalovirus infection and enhancement of this defense pathway by interleukin 12 administration. J. Exp. Med. 182:1045.
    • (1995) J. Exp. Med. , vol.182 , pp. 1045
    • Orange, J.S.1    Wang, B.2    Terhorst, C.3    Biron, C.A.4
  • 20
    • 0028071922 scopus 로고
    • In vivo treatment with interleukin 12 protects mice from immune abnormalities observed during murine acquired immunodeficiency syndrome (MAIDS)
    • Gazzinelli, R. T., N. A. Giese, and H. C. R. Morse. 1994. In vivo treatment with interleukin 12 protects mice from immune abnormalities observed during murine acquired immunodeficiency syndrome (MAIDS). J. Exp. Med. 180:2199.
    • (1994) J. Exp. Med. , vol.180 , pp. 2199
    • Gazzinelli, R.T.1    Giese, N.A.2    Morse, H.C.R.3
  • 21
    • 0028266819 scopus 로고
    • Effects of IL-12 on the response and susceptibility to experimental viral infections
    • Orange, J. S., S. F. Wolf, and C. A. Biron. 1994. Effects of IL-12 on the response and susceptibility to experimental viral infections. J. Immunol. 152:1253.
    • (1994) J. Immunol. , vol.152 , pp. 1253
    • Orange, J.S.1    Wolf, S.F.2    Biron, C.A.3
  • 22
    • 0030997139 scopus 로고    scopus 로고
    • Interleukin-12 inhibits hepatitis B virus replication in transgenic mice
    • Cavanaugh, V. J., L. G. Guidotti, and F. V. Chisari. 1997. Interleukin-12 inhibits hepatitis B virus replication in transgenic mice. J. Virol. 71:3236.
    • (1997) J. Virol. , vol.71 , pp. 3236
    • Cavanaugh, V.J.1    Guidotti, L.G.2    Chisari, F.V.3
  • 24
    • 0033556145 scopus 로고    scopus 로고
    • IL-12 is not required for induction of type 1 cytokine responses in viral infections
    • Oxenius, A., U. Karrer, R. M. Zinkernagel, and H. Hengartner. 1999. IL-12 is not required for induction of type 1 cytokine responses in viral infections. J. Immunol. 162:965.
    • (1999) J. Immunol. , vol.162 , pp. 965
    • Oxenius, A.1    Karrer, U.2    Zinkernagel, R.M.3    Hengartner, H.4
  • 25
    • 0029819130 scopus 로고    scopus 로고
    • Interleukin-4 mediates down regulation of antiviral cytokine expression and cytotoxic T-lymphocyte responses and exacerbates vaccinia virus infection in vivo
    • Sharma, D. P. A. J. Ramsay, D. J. Maguire, M. S. Rolph, and I. A. Ramshaw. 1996. Interleukin-4 mediates down regulation of antiviral cytokine expression and cytotoxic T-lymphocyte responses and exacerbates vaccinia virus infection in vivo. J. Virol. 70:7103.
    • (1996) J. Virol. , vol.70 , pp. 7103
    • Sharma, D.P.1    Ramsay, A.J.2    Maguire, D.J.3    Rolph, M.S.4    Ramshaw, I.A.5
  • 26
    • 0031452187 scopus 로고    scopus 로고
    • Resistance to and recovery from lethal influenza virus infection in B lymphocyte-deficient mice
    • Graham, M. B., and T. J. Braciale. 1997. Resistance to and recovery from lethal influenza virus infection in B lymphocyte-deficient mice. J. Exp. Med. 186:2063.
    • (1997) J. Exp. Med. , vol.186 , pp. 2063
    • Graham, M.B.1    Braciale, T.J.2
  • 27
    • 0029899290 scopus 로고    scopus 로고
    • Interleukin-4 causes delayed virus clearance in influenza virus-infected mice
    • Moran, T. M., H. Isobe, A. Fernandez-Sesma, and J. L. Schulman. 1996. Interleukin-4 causes delayed virus clearance in influenza virus-infected mice. J. Virol. 70:5230.
    • (1996) J. Virol. , vol.70 , pp. 5230
    • Moran, T.M.1    Isobe, H.2    Fernandez-Sesma, A.3    Schulman, J.L.4
  • 29
    • 0030874032 scopus 로고    scopus 로고
    • Overexpression of interleukin-4 delays virus clearance in mice infected with respiratory syncytial virus
    • Fischer, J. E., J. E. Johnson, R. K. Kuli-Zade. T. R. Johnson, S. Aung, R. A. Parker, and B. S. Graham. 1997. Overexpression of interleukin-4 delays virus clearance in mice infected with respiratory syncytial virus. J. Virol. 71: 8672.
    • (1997) J. Virol. , vol.71 , pp. 8672
    • Fischer, J.E.1    Johnson, J.E.2    Kuli-Zade, R.K.3    Johnson, T.R.4    Aung, S.5    Parker, R.A.6    Graham, B.S.7
  • 30
  • 32
    • 0027361744 scopus 로고
    • Effects of virally expressed interleukin-10 on vaccinia virus infection in mice
    • Kurilla, M. G., S. Swaminathan, R. M. Welsh, E. Kieff, and R. R. Brutkiewicz. 1993. Effects of virally expressed interleukin-10 on vaccinia virus infection in mice. J. Virol. 67:7623.
    • (1993) J. Virol. , vol.67 , pp. 7623
    • Kurilla, M.G.1    Swaminathan, S.2    Welsh, R.M.3    Kieff, E.4    Brutkiewicz, R.R.5
  • 33
    • 0032486280 scopus 로고    scopus 로고
    • The role of IL-10 in mouse hepatitis virus-induced demyelinating encephalomyelitis
    • Lin, M. T., D. R. Hinton, B. Parra, S. A. Stohlman, and R. C. van der Veen. 1998. The role of IL-10 in mouse hepatitis virus-induced demyelinating encephalomyelitis, Virology 245:270.
    • (1998) Virology , vol.245 , pp. 270
    • Lin, M.T.1    Hinton, D.R.2    Parra, B.3    Stohlman, S.A.4    Van Der Veen, R.C.5
  • 35
    • 0027488067 scopus 로고
    • Inhibition of viral replication by interferon-γ-induced nitric oxide synthase
    • Karupiah, G., Q. W. Xie, R. M. Buller, C. Nathan, C. Duarte, and J. D. MacMicking. 1993. Inhibition of viral replication by interferon-γ-induced nitric oxide synthase. Science 261:1445.
    • (1993) Science , vol.261 , pp. 1445
    • Karupiah, G.1    Xie, Q.W.2    Buller, R.M.3    Nathan, C.4    Duarte, C.5    MacMicking, J.D.6
  • 36
    • 0030959410 scopus 로고    scopus 로고
    • Suppression of herpes simplex virus type 1 (HSV-1)-induced pneumonia in mice by inhibition of inducible nitric oxide synthase (iNOS, NOS2)
    • Adler, H., J. L. Beland, N. C. Del-Pan, L. Kobzik, J. P. Brewer, T. R. Martin, and I. J. Rimin. 1997. Suppression of herpes simplex virus type 1 (HSV-1)-induced pneumonia in mice by inhibition of inducible nitric oxide synthase (iNOS, NOS2). J. Exp. Med. 185:1533.
    • (1997) J. Exp. Med. , vol.185 , pp. 1533
    • Adler, H.1    Beland, J.L.2    Del-Pan, N.C.3    Kobzik, L.4    Brewer, J.P.5    Martin, T.R.6    Rimin, I.J.7
  • 37
    • 0028658374 scopus 로고
    • Nitric oxide produced by human B lymphocytes inhibits apoptosis and Epstein-Barr virus reactivation
    • Mannick, J. B., K. Asano, K. Izumi, E. Kieff, and J. S. Stamler. 1994. Nitric oxide produced by human B lymphocytes inhibits apoptosis and Epstein-Barr virus reactivation. Cell 79:1137.
    • (1994) Cell , vol.79 , pp. 1137
    • Mannick, J.B.1    Asano, K.2    Izumi, K.3    Kieff, E.4    Stamler, J.S.5
  • 39
    • 0029031980 scopus 로고
    • Inhibition of viral replication by nitic oxide and its reversal by ferrous sulfate and tricarboxylic acid cycle metabolites
    • Karupiah, G., and N. Harris. 1995. Inhibition of viral replication by nitic oxide and its reversal by ferrous sulfate and tricarboxylic acid cycle metabolites. J. Exp. Med. 181:2171.
    • (1995) J. Exp. Med. , vol.181 , pp. 2171
    • Karupiah, G.1    Harris, N.2
  • 40
    • 0029819871 scopus 로고    scopus 로고
    • A recombinant vaccinia virus encoding inducible nitric oxide synthase is attenuated in vivo
    • Rolph, M. S., W. B. Cowden, C. J. Medveczky, and I. A. Ramshaw. 1996. A recombinant vaccinia virus encoding inducible nitric oxide synthase is attenuated in vivo. J. Virol. 70:7678.
    • (1996) J. Virol. , vol.70 , pp. 7678
    • Rolph, M.S.1    Cowden, W.B.2    Medveczky, C.J.3    Ramshaw, I.A.4
  • 41
    • 0029985795 scopus 로고    scopus 로고
    • Nitric oxide production is increased during murine vaccinia virus infection, but may not be essential for virus clearance
    • Rolph, M. S., I. A. Ramshaw, K. A. Rockett, J. Ruby, and W. B. Cowden. 1996. Nitric oxide production is increased during murine vaccinia virus infection, but may not be essential for virus clearance. Virology 217:470.
    • (1996) Virology , vol.217 , pp. 470
    • Rolph, M.S.1    Ramshaw, I.A.2    Rockett, K.A.3    Ruby, J.4    Cowden, W.B.5
  • 42
    • 0029078587 scopus 로고
    • Cytokine receptors encoded by poxviruses: A lesson in cytokine biology
    • Alcami, A., and G. L. Smith. 1995. Cytokine receptors encoded by poxviruses: a lesson in cytokine biology. Immunol. Today 16:474.
    • (1995) Immunol. Today , vol.16 , pp. 474
    • Alcami, A.1    Smith, G.L.2
  • 44
    • 0027521572 scopus 로고
    • Interleukin-10-deficient mice develop chronic enterocolitis
    • Kuhn, R., J. Lohler, D. Rennick, K. Rajewsky, and W. Muller. 1993. Interleukin-10-deficient mice develop chronic enterocolitis. Cell 75:263.
    • (1993) Cell , vol.75 , pp. 263
    • Kuhn, R.1    Lohler, J.2    Rennick, D.3    Rajewsky, K.4    Muller, W.5
  • 45
    • 0027400726 scopus 로고
    • Multiple defects of immune cell function in mice with disrupted interferon-γ genes
    • Dalton, D. K., M. S. Pitts, S. Keshav, I. S. Figari, A. Bradley, and T. A. Stewart. 1993. Multiple defects of immune cell function in mice with disrupted interferon-γ genes. Science 259:1739.
    • (1993) Science , vol.259 , pp. 1739
    • Dalton, D.K.1    Pitts, M.S.2    Keshav, S.3    Figari, I.S.4    Bradley, A.5    Stewart, T.A.6
  • 48
    • 0025217221 scopus 로고
    • Immunodeficient mice recover from infection with vaccinia virus expressing interferon-γ
    • Kohonen-Corish, M. R., N. J. King, C. E. Woodhams, and I. A. Ramshaw, 1990. Immunodeficient mice recover from infection with vaccinia virus expressing interferon-γ. Eur. J. Immunol. 20:157.
    • (1990) Eur. J. Immunol. , vol.20 , pp. 157
    • Kohonen-Corish, M.R.1    King, N.J.2    Woodhams, C.E.3    Ramshaw, I.A.4
  • 49
    • 0032554784 scopus 로고    scopus 로고
    • Differences between IL-4Rα-deficient and IL-4-deficient mice reveal a role for IL-13 in the regulation of Th2 responses
    • Barner, M., M. Mohrs, F. Brombacher, and M. Kopf. 1998. Differences between IL-4Rα-deficient and IL-4-deficient mice reveal a role for IL-13 in the regulation of Th2 responses. Curr. Biol. 8:669.
    • (1998) Curr. Biol. , vol.8 , pp. 669
    • Barner, M.1    Mohrs, M.2    Brombacher, F.3    Kopf, M.4
  • 51
    • 0029876629 scopus 로고    scopus 로고
    • Stat6 is required for mediating responses to IL-4 and for development of Th2 cells
    • Kaplan, M. H., U. Schindler, S. T. Smiley, and M. J. Grusby. 1996. Stat6 is required for mediating responses to IL-4 and for development of Th2 cells. Immunity 4:313.
    • (1996) Immunity , vol.4 , pp. 313
    • Kaplan, M.H.1    Schindler, U.2    Smiley, S.T.3    Grusby, M.J.4
  • 54
    • 0031571205 scopus 로고    scopus 로고
    • Characterization of IL-12 receptor β1 chain (IL-12Rβ1)-deficient mice: IL-12Rβ1 is an essential component of the functional mouse IL-12 receptor
    • Wu, C., J. Ferrante, M. K. Gately, and J. Magram. 1997. Characterization of IL-12 receptor β1 chain (IL-12Rβ1)-deficient mice: IL-12Rβ1 is an essential component of the functional mouse IL-12 receptor. J. Immunol. 159:1658.
    • (1997) J. Immunol. , vol.159 , pp. 1658
    • Wu, C.1    Ferrante, J.2    Gately, M.K.3    Magram, J.4
  • 55
    • 0029937270 scopus 로고    scopus 로고
    • Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice
    • Kaplan, M. H., Y. L. Sun, T. Hoey, and M. J. Grusby. 1996. Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice. Nature 382:174.
    • (1996) Nature , vol.382 , pp. 174
    • Kaplan, M.H.1    Sun, Y.L.2    Hoey, T.3    Grusby, M.J.4
  • 61
    • 0026525006 scopus 로고
    • Gamma interferon-dependent clearance of cytomegalovirus infection in salivary glands
    • Lucin, P., I. Pavic, B. Polic, S. Jonjic, and U. Koszinowski. 1992. Gamma interferon-dependent clearance of cytomegalovirus infection in salivary glands. J. Virol. 66:1977.
    • (1992) J. Virol. , vol.66 , pp. 1977
    • Lucin, P.1    Pavic, I.2    Polic, B.3    Jonjic, S.4    Koszinowski, U.5
  • 62
    • 0026699318 scopus 로고
    • In vivo depletion of interferon-γ leads to susceptibility of A/J mice to mouse hepatitis virus 3 infection
    • Lucchiari, M. A., M. Modolell, K. Eichmann, and C. A. Pereira. 1992. In vivo depletion of interferon-γ leads to susceptibility of A/J mice to mouse hepatitis virus 3 infection. Immunobiology 185:475.
    • (1992) Immunobiology , vol.185 , pp. 475
    • Lucchiari, M.A.1    Modolell, M.2    Eichmann, K.3    Pereira, C.A.4
  • 63
    • 0028169445 scopus 로고
    • IFN-γ receptor-deficient mice generate antiviral Th1-characteristic cytokine profiles but altered antibody responses
    • Schijns, V. E., B. L. Haagmans, E. O. Rijke, S. Huang, M. Aguet, and M. C. Horzinek. 1994. IFN-γ receptor-deficient mice generate antiviral Th1-characteristic cytokine profiles but altered antibody responses. J. Immunol. 153: 2029.
    • (1994) J. Immunol. , vol.153 , pp. 2029
    • Schijns, V.E.1    Haagmans, B.L.2    Rijke, E.O.3    Huang, S.4    Aguet, M.5    Horzinek, M.C.6
  • 64
    • 0030971472 scopus 로고    scopus 로고
    • Gamma interferon is not essential for recovery from acute infection with murine gammaherpesvirus 68
    • Sarawar, S. R., R. D. Cardin, J. W. Brooks, M. Mehrpooya, A. M. Hamilton Easton, X. Y. Mo, and P. C. Doherty. 1997. Gamma interferon is not essential for recovery from acute infection with murine gammaherpesvirus 68. J. Virol. 71:3916.
    • (1997) J. Virol. , vol.71 , pp. 3916
    • Sarawar, S.R.1    Cardin, R.D.2    Brooks, J.W.3    Mehrpooya, M.4    Easton, A.M.H.5    Mo, X.Y.6    Doherty, P.C.7
  • 66
    • 0028957492 scopus 로고
    • Mechanism of interleukin 12-mediated toxicities during experimental viral infections: Role of tumor necrosis factor and glucocorticoids
    • Orange, J. S., T. P. Salazar-Mather, S. M. Opal, R. L. Spencer, A. H. Miller, B. S. McEwen, and C. A. Biron. 1995. Mechanism of interleukin 12-mediated toxicities during experimental viral infections: role of tumor necrosis factor and glucocorticoids. J. Exp. Med. 181:901.
    • (1995) J. Exp. Med. , vol.181 , pp. 901
    • Orange, J.S.1    Salazar-Mather, T.P.2    Opal, S.M.3    Spencer, R.L.4    Miller, A.H.5    McEwen, B.S.6    Biron, C.A.7
  • 67
    • 0028863450 scopus 로고
    • IL-12 promotes enhanced recovery from vesicular stomatitis virus infection of the central nervous system
    • Bi, Z., P. Quandt, T. Komatsu, M. Barna, and C. S. Reiss. 1995. IL-12 promotes enhanced recovery from vesicular stomatitis virus infection of the central nervous system. J. Immunol. 155:5684.
    • (1995) J. Immunol. , vol.155 , pp. 5684
    • Bi, Z.1    Quandt, P.2    Komatsu, T.3    Barna, M.4    Reiss, C.S.5
  • 68
    • 0031918989 scopus 로고    scopus 로고
    • Immunobiology of interleukin-12
    • Trinchieri, G. 1998. Immunobiology of interleukin-12. Immunol. Res. 17:269.
    • (1998) Immunol. Res. , vol.17 , pp. 269
    • Trinchieri, G.1
  • 70
    • 0030895747 scopus 로고    scopus 로고
    • Intracellular antimicrobial activity in the absence of interferon-gamma: Effect of interleukin-12 in experimental visceral leishmaniasis in interferon-γ gene-disrupted mice
    • Taylor, A. P., and H. W. Murray. 1997. Intracellular antimicrobial activity in the absence of interferon-gamma: effect of interleukin-12 in experimental visceral leishmaniasis in interferon-γ gene-disrupted mice. J. Exp. Med. 185:1231.
    • (1997) J. Exp. Med. , vol.185 , pp. 1231
    • Taylor, A.P.1    Murray, H.W.2
  • 72
    • 0030060232 scopus 로고    scopus 로고
    • An absolute and restricted requirement for IL-12 in natural killer cell IFN-γ production and antiviral defense: Studies of natural killer and T cell responses in contrasting viral infections
    • Orange, J. S., and C. A. Biron. 1996. An absolute and restricted requirement for IL-12 in natural killer cell IFN-γ production and antiviral defense: studies of natural killer and T cell responses in contrasting viral infections. J. Immunol. 156:1138.
    • (1996) J. Immunol. , vol.156 , pp. 1138
    • Orange, J.S.1    Biron, C.A.2
  • 73
    • 0029582926 scopus 로고
    • The roles of perforin-and Fas-dependent cytotoxicity in protection against cytopathic and noncytopathic viruses
    • Kagi, D., P. Seiler, J. Pavlovic, B. Ledermann, K. Burki, R. M. Zinkernagel, and H. Hengartner. 1995. The roles of perforin-and Fas-dependent cytotoxicity in protection against cytopathic and noncytopathic viruses. Eur. J. Immunol. 25: 3256.
    • (1995) Eur. J. Immunol. , vol.25 , pp. 3256
    • Kagi, D.1    Seiler, P.2    Pavlovic, J.3    Ledermann, B.4    Burki, K.5    Zinkernagel, R.M.6    Hengartner, H.7
  • 74
    • 0027240219 scopus 로고
    • Interleukin 10 (IL-10) inhibits human lymphocyte interferon γ-production by suppressing natural killer cell stimulatory factor/IL-12 synthesis in accessory cells
    • D'Andrea, A., M. Aste-Amezaga, N. M. Valiante, X. Ma, M. Kubin, and G. Trinchieri. 1993. Interleukin 10 (IL-10) inhibits human lymphocyte interferon γ-production by suppressing natural killer cell stimulatory factor/IL-12 synthesis in accessory cells. J. Exp. Med. 178:1041.
    • (1993) J. Exp. Med. , vol.178 , pp. 1041
    • D'Andrea, A.1    Aste-Amezaga, M.2    Valiante, N.M.3    Ma, X.4    Kubin, M.5    Trinchieri, G.6
  • 75
    • 0029831666 scopus 로고    scopus 로고
    • High level IL-12 production by murine dendritic cells: Upregulation via MHC class II and CD40 molecules and downregulation by IL-4 and IL-10.
    • Published erratum appears in 1996 J. Exp. Med. 184:1591.
    • Koch, F., U. Stanzl, P. Jennewein, K. Janke, C. Heufler, E. Kampgen, N. Romani, and G. Schuler. 1996. High level IL-12 production by murine dendritic cells: upregulation via MHC class II and CD40 molecules and downregulation by IL-4 and IL-10. [Published erratum appears in 1996 J. Exp. Med. 184:1591.] J. Exp. Med. 184:741.
    • (1996) J. Exp. Med. , vol.184 , pp. 741
    • Koch, F.1    Stanzl, U.2    Jennewein, P.3    Janke, K.4    Heufler, C.5    Kampgen, E.6    Romani, N.7    Schuler, G.8
  • 77
    • 0031091727 scopus 로고    scopus 로고
    • Both innate and acquired immunity to Listeria monocytogenes infection are increased in IL-10-deficient mice
    • Dai, W. J., G. Kohler, and F. Brombacher. 1997. Both innate and acquired immunity to Listeria monocytogenes infection are increased in IL-10-deficient mice. J. Immunol. 158:2259.
    • (1997) J. Immunol. , vol.158 , pp. 2259
    • Dai, W.J.1    Kohler, G.2    Brombacher, F.3
  • 79
    • 0030002111 scopus 로고    scopus 로고
    • Genetically resistant mice lacking interleukin-12 are susceptible to infection with Leishmania major and mount a polarized Th2 cell response
    • Mattner, F., J. Magram, J. Ferrante, P. Launois, K. Di Padova, R. Behin, M. K. Gately, J. A. Louis, and G. Alber. 1996. Genetically resistant mice lacking interleukin-12 are susceptible to infection with Leishmania major and mount a polarized Th2 cell response. Eur. J. Immunol. 26:1553.
    • (1996) Eur. J. Immunol. , vol.26 , pp. 1553
    • Mattner, F.1    Magram, J.2    Ferrante, J.3    Launois, P.4    Di Padova, K.5    Behin, R.6    Gately, M.K.7    Louis, J.A.8    Alber, G.9
  • 80
    • 0028878655 scopus 로고
    • Interleukin-12 gene expression after viral infection in the mouse
    • Coutelier, J. P., J. Van Broeck, and S. F. Wolf. 1995. Interleukin-12 gene expression after viral infection in the mouse. J. Virol. 69:1955.
    • (1995) J. Virol. , vol.69 , pp. 1955
    • Coutelier, J.P.1    Van Broeck, J.2    Wolf, S.F.3
  • 81
    • 0030047502 scopus 로고    scopus 로고
    • Herpes simplex virus type 1-mediated up-regulation of IL-12 (p40) mRNA expression: Implications in immunopathogenesis and protection
    • Kanangat, S., J. Thomas, S. Gangappa, J. S. Babu, and B. T. Rouse. 1996. Herpes simplex virus type 1-mediated up-regulation of IL-12 (p40) mRNA expression: implications in immunopathogenesis and protection. J. Immunol 156:1110.
    • (1996) J. Immunol , vol.156 , pp. 1110
    • Kanangat, S.1    Thomas, J.2    Gangappa, S.3    Babu, J.S.4    Rouse, B.T.5
  • 82
    • 0029929032 scopus 로고    scopus 로고
    • Characterization of early IL-12, IFN-αβ, and TNF effects on antiviral state and NK cell responses during murine cytomegalovirus infection
    • Orange, J. S., and C. A. Biron. 1996. Characterization of early IL-12, IFN-αβ, and TNF effects on antiviral state and NK cell responses during murine cytomegalovirus infection. J. Immunol. 156:4746.
    • (1996) J. Immunol. , vol.156 , pp. 4746
    • Orange, J.S.1    Biron, C.A.2
  • 85
    • 0028110057 scopus 로고
    • Anti-IL-4 treatment at immunization modulates cytokine expression, reduces illness, and increases cytotoxic T lymphocyte activity in mice challenged with respiratory syncytial virus
    • Tang, Y. W., and B. S. Graham. 1994. Anti-IL-4 treatment at immunization modulates cytokine expression, reduces illness, and increases cytotoxic T lymphocyte activity in mice challenged with respiratory syncytial virus. J. Clin. Invest. 94:1953.
    • (1994) J. Clin. Invest. , vol.94 , pp. 1953
    • Tang, Y.W.1    Graham, B.S.2
  • 86
    • 0025167636 scopus 로고
    • Interferon γ is involved in the recovery of athymic nude mice from recombinant vaccinia virus/interleukin 2 infection
    • Karupiah, G., R. V. Blanden, and I. A. Ramshaw. 1990. Interferon γ is involved in the recovery of athymic nude mice from recombinant vaccinia virus/interleukin 2 infection. J. Exp. Med. 172:1495.
    • (1990) J. Exp. Med. , vol.172 , pp. 1495
    • Karupiah, G.1    Blanden, R.V.2    Ramshaw, I.A.3
  • 87
    • 0025764321 scopus 로고
    • Local production of tumor necrosis factor encoded by recombinant vaccinia virus is effective in controlling viral replication in vivo
    • Sambhi, S. K., M. R. Kohonen-Corish, and I. A. Ramshaw. 1991. Local production of tumor necrosis factor encoded by recombinant vaccinia virus is effective in controlling viral replication in vivo. Proc. Natl. Acad. Sci. USA 88:4025.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 4025
    • Sambhi, S.K.1    Kohonen-Corish, M.R.2    Ramshaw, I.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.