Trans 10, cis 12-conjugated linoleic acid induces mitochondria-related apoptosis and lysosomal destabilization in rat hepatoma cells

Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids

Volumn 1735, Issue 3, 2005, Pages 176-184

  Yamasaki, Masao ^a,b   Miyamoto, Yumi ^b   Chujo, Hitomi ^b,c   Nishiyama, Kazuo ^a   Tachibana, Hirofumi ^b   Yamada, Koji ^b  

^a UNIVERSITY OF MIYAZAKI   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

^c NAKAMURA GAKUEN UNIVERSITY   (Japan)

Author keywords

Apoptosis; Caspase; Conjugated linoleic acid; Hepatoma; Lysosome

Indexed keywords

ACRIDINE ORANGE; BETA N ACETYLHEXOSAMINIDASE; CASPASE 3; CASPASE 3 INHIBITOR; CASPASE 9; CASPASE 9 INHIBITOR; CONJUGATED LINOLEIC ACID; CYTOCHROME C; ENZYME INHIBITOR; PROTEIN BAX; PROTEIN BID; UNCLASSIFIED DRUG; BAX PROTEIN, RAT; BID PROTEIN, RAT; CARRIER PROTEIN; CASP3 PROTEIN, RAT; CASP9 PROTEIN, RAT; CASPASE; PROTEIN BCL 2; TRANS 10,CIS 12 CONJUGATED LINOLEIC ACID; TRANS-10,CIS-12-CONJUGATED LINOLEIC ACID;

ANIMAL CELL; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL ISOLATION; CONTROLLED STUDY; CYTOSOL; CYTOTOXICITY; ENZYME ACTIVATION; HEPATOMA CELL; LIVER CELL CARCINOMA; LIVER LYSOSOME; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN SECRETION; RAT; ANIMAL; DRUG EFFECT; KINETICS; LIVER TUMOR; METABOLISM; PHYSIOLOGY; TUMOR CELL LINE;

ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BH3 INTERACTING DOMAIN DEATH AGONIST PROTEIN; CARCINOMA, HEPATOCELLULAR; CARRIER PROTEINS; CASPASE 3; CASPASE 9; CASPASES; CELL LINE, TUMOR; ENZYME ACTIVATION; KINETICS; LINOLEIC ACIDS, CONJUGATED; LIVER NEOPLASMS; MITOCHONDRIA; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS;

EID: 23744459793     PISSN: 13881981     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbalip.2005.05.010     Document Type: Article

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