Synthesis of tripeptides as potent Yersinia protein tyrosine phosphatase inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 18, 2005, Pages 4037-4042

  Lee, Kyeong ^a,c   Boovanahalli, Shanthaveerappa K ^c   Nam, Ky Youb ^d   Kang, Sang Uk ^a   Lee, Mijeoung ^c   Phan, Jason ^a   Wu, Li ^b   Waugh, David S ^a   Zhang, Zhong Yin ^b   Kyoung, Tai No ^d   Jung, Jun Lee ^c   Burke Jr , Terrence R ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^c Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^d Yonsei University   (South Korea)

Author keywords

Bioterrorism; PTP1B; pTyr mimetics; Tripeptides; YopH

Indexed keywords

PROTEIN TYROSINE PHOSPHATASE 1B; PROTEIN TYROSINE PHOSPHATASE INHIBITOR; TRIPEPTIDE DERIVATIVE;

AMINO TERMINAL SEQUENCE; ARTICLE; DRUG ACTIVITY; DRUG BINDING; DRUG POTENCY; DRUG SYNTHESIS; ENZYME BINDING; ENZYME INHIBITION; IC 50; YERSINIA;

BACTERIAL OUTER MEMBRANE PROTEINS; BINDING SITES; ENZYME INHIBITORS; HUMANS; INHIBITORY CONCENTRATION 50; MODELS, MOLECULAR; MOLECULAR STRUCTURE; OLIGOPEPTIDES; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTEIN-TYROSINE-PHOSPHATASE; STRUCTURE-ACTIVITY RELATIONSHIP; YERSINIA;

YERSINIA;

EID: 23644432990     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2005.06.027     Document Type: Article

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