-
1
-
-
0036807325
-
-
For a recent review, see: Hooft van Huijsduijnen, R.; Bombrun, A.; Swinnen, D. Drug Discov. Today 2002, 7, 1013-1019.
-
(2002)
Drug Discov. Today
, vol.7
, pp. 1013-1019
-
-
Hooft Van Huijsduijnen, R.1
Bombrun, A.2
Swinnen, D.3
-
2
-
-
0036715628
-
-
For a recent review, see Johnson, T. O.; Ermolieff, J.; Jirousek, M. R. Nat. Rev. Drug Discov. 2002, 1, 696-709.
-
(2002)
Nat. Rev. Drug Discov.
, vol.1
, pp. 696-709
-
-
Johnson, T.O.1
Ermolieff, J.2
Jirousek, M.R.3
-
3
-
-
0033610844
-
-
Harder, K. W.; Moller, N. P. H.; Peacock, J. W.; Jirik, F. R. J. Biol. Chem. 1998, 273, 31890-31900.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 31890-31900
-
-
Harder, K.W.1
Moller, N.P.H.2
Peacock, J.W.3
Jirik, F.R.4
-
4
-
-
18344375627
-
-
(a) Lazo, J. S.; Nemoto, K.; Pestell, K. E.; Cooley, K.; Southwick, E. C.; Mitchell, D. A.; Furey, W.; Gussio, R.; Zaharevitz, D. W.; Joo, B.; Wipf, P. Mol. Pharmacol. 2002, 61, 720-728.
-
(2002)
Mol. Pharmacol.
, vol.61
, pp. 720-728
-
-
Lazo, J.S.1
Nemoto, K.2
Pestell, K.E.3
Cooley, K.4
Southwick, E.C.5
Mitchell, D.A.6
Furey, W.7
Gussio, R.8
Zaharevitz, D.W.9
Joo, B.10
Wipf, P.11
-
5
-
-
0029119560
-
-
(b) Galaktionov, K.; Lee, A. K.; Eckstein, J.; Draetta, G.; Meckler, J.; Loda, M.; Beach, D. Science 1995, 269, 1575-1577.
-
(1995)
Science
, vol.269
, pp. 1575-1577
-
-
Galaktionov, K.1
Lee, A.K.2
Eckstein, J.3
Draetta, G.4
Meckler, J.5
Loda, M.6
Beach, D.7
-
6
-
-
0035347144
-
-
Penninger, J. M.; Irie-Sasaki, J.; Sasaki, T.; Oliveira-dos-Santos, A. J. Nat. Immunol. 2001, 2, 389-396.
-
(2001)
Nat. Immunol.
, vol.2
, pp. 389-396
-
-
Penninger, J.M.1
Irie-Sasaki, J.2
Sasaki, T.3
Oliveira-dos-Santos, A.J.4
-
7
-
-
0033964846
-
-
DeVinney, R.; Steele-Mortimer, O.; Finlay, B. B. Trends Microbiol. 2000, 8, 29-33.
-
(2000)
Trends Microbiol.
, vol.8
, pp. 29-33
-
-
DeVinney, R.1
Steele-Mortimer, O.2
Finlay, B.B.3
-
8
-
-
0031771146
-
-
For reviews, see: (a) Burke, T. R., Jr.; Zhang, Z.-Y. Biopolymers 1998, 47, 225-241. (b) Burke, T. R., Jr.; Yao, Z.-J.; Liu, D.-G.; Voigt, J.; Gao, Y. Biopolymers 2001, 60, 32-44. (c) Ripka, W. C. Annu. Rep. Med. Chem. 2000, 35, 231-250.
-
(1998)
Biopolymers
, vol.47
, pp. 225-241
-
-
Burke Jr., T.R.1
Zhang, Z.-Y.2
-
9
-
-
0034957263
-
-
For reviews, see: (a) Burke, T. R., Jr.; Zhang, Z.-Y. Biopolymers 1998, 47, 225-241. (b) Burke, T. R., Jr.; Yao, Z.-J.; Liu, D.-G.; Voigt, J.; Gao, Y. Biopolymers 2001, 60, 32-44. (c) Ripka, W. C. Annu. Rep. Med. Chem. 2000, 35, 231-250.
-
(2001)
Biopolymers
, vol.60
, pp. 32-44
-
-
Burke Jr., T.R.1
Yao, Z.-J.2
Liu, D.-G.3
Voigt, J.4
Gao, Y.5
-
10
-
-
35448947581
-
-
For reviews, see: (a) Burke, T. R., Jr.; Zhang, Z.-Y. Biopolymers 1998, 47, 225-241. (b) Burke, T. R., Jr.; Yao, Z.-J.; Liu, D.-G.; Voigt, J.; Gao, Y. Biopolymers 2001, 60, 32-44. (c) Ripka, W. C. Annu. Rep. Med. Chem. 2000, 35, 231-250.
-
(2000)
Annu. Rep. Med. Chem.
, vol.35
, pp. 231-250
-
-
Ripka, W.C.1
-
11
-
-
0032559056
-
-
(a) Groves, M. R.; Yao, Z.-J.; Roller, P. P.; Burke, T. R., Jr.; Barford, D. Biochemistry 1998, 37, 17773-17783.
-
(1998)
Biochemistry
, vol.37
, pp. 17773-17783
-
-
Groves, M.R.1
Yao, Z.-J.2
Roller, P.P.3
Burke Jr., T.R.4
Barford, D.5
-
12
-
-
0035861668
-
-
(b) Shen, K.; Keng, Y.-F.; Wu, L.; Guo, X.-L.; Lawrence, D. S.; Zhang, Z.-Y. J. Biol. Chem. 2001, 276, 47311-47319.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 47311-47319
-
-
Shen, K.1
Keng, Y.-F.2
Wu, L.3
Guo, X.-L.4
Lawrence, D.S.5
Zhang, Z.-Y.6
-
13
-
-
0029930442
-
-
Burke, T. R., Jr.; Ye, B.; Akamatsu, M.; Ford, H., Jr.; Yan, X.; Kole, H. K.; Wolf, G.; Shoelson, S. E.; Roller, P. P. J. Med. Chem. 1996, 39, 1021-1027.
-
(1996)
J. Med. Chem.
, vol.39
, pp. 1021-1027
-
-
Burke Jr., T.R.1
Ye, B.2
Akamatsu, M.3
Ford Jr., H.4
Yan, X.5
Kole, H.K.6
Wolf, G.7
Shoelson, S.E.8
Roller, P.P.9
-
14
-
-
0034629107
-
-
Andersen, H. S.; Iversen, L. F.; Jeppesen, C. B.; Branner, S.; Norris, K.; Rasmussen, H. B.; Moller, K. B.; Moller, N. P. H. J. Biol. Chem. 2000, 275, 7101-7108.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 7101-7108
-
-
Andersen, H.S.1
Iversen, L.F.2
Jeppesen, C.B.3
Branner, S.4
Norris, K.5
Rasmussen, H.B.6
Moller, K.B.7
Moller, N.P.H.8
-
15
-
-
0036235963
-
-
Leung, C.; Grzyb, J.; Lee, J.; Meyer, N.; Hum, G.; Jia, C.; Liu, S.; Taylor, S. D. Bioorg. Med. Chem. 2002, 10, 2309-2323.
-
(2002)
Bioorg. Med. Chem.
, vol.10
, pp. 2309-2323
-
-
Leung, C.1
Grzyb, J.2
Lee, J.3
Meyer, N.4
Hum, G.5
Jia, C.6
Liu, S.7
Taylor, S.D.8
-
16
-
-
0037430643
-
-
Larsen, S. D.; Stevens, F. C.; Lindberg, T. J.; Bodnar, P. M.; O'Sullivan, T. J.; Schostarez, H. J.; Palazuk, B. J.; Bleasdale, J. E. Bioorg. Med. Chem. Lett. 2003, 13, 971-975.
-
(2003)
Bioorg. Med. Chem. Lett.
, vol.13
, pp. 971-975
-
-
Larsen, S.D.1
Stevens, F.C.2
Lindberg, T.J.3
Bodnar, P.M.4
O'Sullivan, T.J.5
Schostarez, H.J.6
Palazuk, B.J.7
Bleasdale, J.E.8
-
17
-
-
0035939390
-
-
(a) Chen, Y. T.; Onaran, M. B.; Doss, C. J.; Seto, C. T. Bioorg. Med. Chem. Lett. 2001, 11, 1935-1938.
-
(2001)
Bioorg. Med. Chem. Lett.
, vol.11
, pp. 1935-1938
-
-
Chen, Y.T.1
Onaran, M.B.2
Doss, C.J.3
Seto, C.T.4
-
19
-
-
0038626736
-
-
(c) Chen, Y. T.; Xie, J.; Seto, C. T. J. Org. Chem. 2003, 68, 4123-4125.
-
(2003)
J. Org. Chem.
, vol.68
, pp. 4123-4125
-
-
Chen, Y.T.1
Xie, J.2
Seto, C.T.3
-
20
-
-
0742296298
-
-
note
-
See Supporting Information for a comparison of electron density calculations of phenyl phosphate dianion and 2-phenyl-1-hydroxycyclobut-1-ene-3, 4-dione monoanion.
-
-
-
-
21
-
-
0037592558
-
-
a of 2-phenyl-1-hydroxycyclobut-1-ene-3,4-dione has been reported as 0.37 or -0.22. (a) Smutney, E. J.; Caserio, M. C.; Roberts, J. D. J. Am. Chem. Soc. 1960, 82, 1793-1801. (b) Patton, E.; West, R. J. Am. Chem. Soc. 1973, 95, 8703-8707.
-
(1960)
J. Am. Chem. Soc.
, vol.82
, pp. 1793-1801
-
-
Smutney, E.J.1
Caserio, M.C.2
Roberts, J.D.3
-
22
-
-
33947084987
-
-
a of 2-phenyl-1-hydroxycyclobut-1-ene-3,4-dione has been reported as 0.37 or -0.22. (a) Smutney, E. J.; Caserio, M. C.; Roberts, J. D. J. Am. Chem. Soc. 1960, 82, 1793-1801. (b) Patton, E.; West, R. J. Am. Chem. Soc. 1973, 95, 8703-8707.
-
(1973)
J. Am. Chem. Soc.
, vol.95
, pp. 8703-8707
-
-
Patton, E.1
West, R.2
-
24
-
-
0020056870
-
-
Burka, L. T.; Doran, J.; Wilson, B. J. Biochem. Pharmacol. 1982, 31, 79-84.
-
(1982)
Biochem. Pharmacol.
, vol.31
, pp. 79-84
-
-
Burka, L.T.1
Doran, J.2
Wilson, B.J.3
-
25
-
-
0037202130
-
-
Sato, K.; Seio, K.; Sekine, M. J. Am. Chem. Soc. 2002, 124, 12715-12724.
-
(2002)
J. Am. Chem. Soc.
, vol.124
, pp. 12715-12724
-
-
Sato, K.1
Seio, K.2
Sekine, M.3
-
26
-
-
0033587115
-
-
Beaulieu, P. L.; Cameron, D. R.; Ferland, J.-M.; Gauthier, J.; Ghiro, E. ; Gillard, J.; Gorys, V.; Poirier, M.; Rancourt, J.; Wernic, D.; Llinas-Brunet, M.; Betageri, R.; Cardozo, M.; Hickey, E. R.; Ingraham, R.; Jakes, S.; Kabcenell, A.; Kirrane, T.; Lukas, S.; Patel, U.; Proudfoot, J.; Sharma, R.; Tong, L.; Moss, N. J. Med. Chem. 1999, 42, 1757-1766.
-
(1999)
J. Med. Chem.
, vol.42
, pp. 1757-1766
-
-
Beaulieu, P.L.1
Cameron, D.R.2
Ferland, J.-M.3
Gauthier, J.4
Ghiro, E.5
Gillard, J.6
Gorys, V.7
Poirier, M.8
Rancourt, J.9
Wernic, D.10
Llinas-Brunet, M.11
Betageri, R.12
Cardozo, M.13
Hickey, E.R.14
Ingraham, R.15
Jakes, S.16
Kabcenell, A.17
Kirrane, T.18
Lukas, S.19
Patel, U.20
Proudfoot, J.21
Sharma, R.22
Tong, L.23
Moss, N.24
more..
-
27
-
-
0028832196
-
-
Chan, P. C. M.; Roon, R. J.; Koerner, J. F.; Taylor, N. J.; Honek, J. F. J. Med. Chem. 1995, 38, 4433-4438.
-
(1995)
J. Med. Chem.
, vol.38
, pp. 4433-4438
-
-
Chan, P.C.M.1
Roon, R.J.2
Koerner, J.F.3
Taylor, N.J.4
Honek, J.F.5
-
28
-
-
15144339410
-
-
Kinney, W. A.; Abou-Gharbia, M.; Garrison, D. T.; Schmid, J.; Kowal, D. M.; Bramlett, D. R.; Miller, T. L.; Tasse, R. P.; Zaleska, M. M.; Moyer, J. A. J. Med. Chem. 1998, 41, 236-246.
-
(1998)
J. Med. Chem.
, vol.41
, pp. 236-246
-
-
Kinney, W.A.1
Abou-Gharbia, M.2
Garrison, D.T.3
Schmid, J.4
Kowal, D.M.5
Bramlett, D.R.6
Miller, T.L.7
Tasse, R.P.8
Zaleska, M.M.9
Moyer, J.A.10
-
30
-
-
37049069690
-
-
Ohno, M.; Yamamoto, Y.; Shirasaki, Y.; Eguchi, S. J. Chem. Soc., Perkin Trans. 1 1993 263-271.
-
(1993)
J. Chem. Soc., Perkin Trans. 1
, pp. 263-271
-
-
Ohno, M.1
Yamamoto, Y.2
Shirasaki, Y.3
Eguchi, S.4
-
31
-
-
0030950702
-
-
Liu, H.; Tomooka, C. S.; Moore, H. W. Synth. Commun. 1997, 27, 2177-2180.
-
(1997)
Synth. Commun.
, vol.27
, pp. 2177-2180
-
-
Liu, H.1
Tomooka, C.S.2
Moore, H.W.3
-
34
-
-
0742313905
-
-
Chen, Y.-Z.; Li, J.-C.; Huang, F.; Chen, L.-Y. Youji Huaxue 1998, 18, 130-136.
-
(1998)
Youji Huaxue
, vol.18
, pp. 130-136
-
-
Chen, Y.-Z.1
Li, J.-C.2
Huang, F.3
Chen, L.-Y.4
-
35
-
-
0742313898
-
-
See Supporting Information
-
See Supporting Information.
-
-
-
-
36
-
-
0037179635
-
-
PTPase inhibitors often show a decrease in potency with increasing pH. See, for example: Andersen, H. S.; Olsen, O. H.; Iversen, L. F.; Sorensen, A. L.; Mortensen, S. B.; Christensen, M. S.; Branner, S.; Hansen, T, K.; Lau, J. F.; Jeppesen, L.; Moran, E.; Su, J.; Bakir, F.; Judge, L.; Shahbaz, M.; Collins, T.; Vo, T.; Newman, M. J.; Ripka, W. C.; Moller, N. P. H. J. Med. Chem. 2002, 45, 4443-4459.
-
(2002)
J. Med. Chem.
, vol.45
, pp. 4443-4459
-
-
Andersen, H.S.1
Olsen, O.H.2
Iversen, L.F.3
Sorensen, A.L.4
Mortensen, S.B.5
Christensen, M.S.6
Branner, S.7
Hansen, T.K.8
Lau, J.F.9
Jeppesen, L.10
Moran, E.11
Su, J.12
Bakir, F.13
Judge, L.14
Shahbaz, M.15
Collins, T.16
Vo, T.17
Newman, M.J.18
Ripka, W.C.19
Moller, N.P.H.20
more..
-
37
-
-
0034507958
-
-
Salmeen, A.; Andersen, J. N.; Myers, M. P.; Tonks, N. K.; Barford, D. Mol. Cell 2000, 6, 1401-1412.
-
(2000)
Mol. Cell
, vol.6
, pp. 1401-1412
-
-
Salmeen, A.1
Andersen, J.N.2
Myers, M.P.3
Tonks, N.K.4
Barford, D.5
-
38
-
-
0028122711
-
-
Stuckey, J. A.; Schubert, H. L.; Fauman, E. B.; Zhang, Z.-Y.; Dixon, J. E.; Saper, M. A. Nature 1994, 370, 571-575.
-
(1994)
Nature
, vol.370
, pp. 571-575
-
-
Stuckey, J.A.1
Schubert, H.L.2
Fauman, E.B.3
Zhang, Z.-Y.4
Dixon, J.E.5
Saper, M.A.6
|