Trifluoromethyl- and difluoromethyl-β-lactams as useful building blocks for the synthesis of fluorinated amino acids, dipeptides, and fluoro-taxoids

Journal of Fluorine Chemistry

Volumn 125, Issue 4, 2004, Pages 487-500

  Kuznetsova, Larisa ^a   Ungureanu, Ioana Maria ^a   Pepe, Antonella ^a   Zanardi, Ilaria ^a   Wu, Xinyuan ^a   Ojima, Iwao ^a  

^a STONY BROOK UNIVERSITY   (United States)

Author keywords

Hydroxy amino acid; Lactam; Difluoromethyl; Dipeptide; Enantiopure; Enzymatic optical resolution; Fluorine containing; Taxoid; Trifluoromethyl

Indexed keywords

AMINO ACID DERIVATIVE; ANTINEOPLASTIC AGENT; AZETIDINE DERIVATIVE; BESTATIN; BETA AMINO ACID; BETA LACTAM; DIPEPTIDE DERIVATIVE; FLUORINE DERIVATIVE; IMINE; KETENE DERIVATIVE; KYNOSTATIN 272; METHYL GROUP; MICROGININ; PACLITAXEL; SULFUR DERIVATIVE; TAXOID; TRIACYLGLYCEROL LIPASE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; CONTROLLED STUDY; CYCLOADDITION; DRUG CYTOTOXICITY; DRUG STRUCTURE; DRUG SYNTHESIS; ENANTIOMER; FLUORINATION; HUMAN; HUMAN CELL; IC 50; OPTICAL RESOLUTION; OZONOLYSIS; SYNTHESIS;

EID: 2342504474     PISSN: 00221139     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jfluchem.2003.12.001     Document Type: Article

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