Synthesis of novel 3'-trifluoromethyl taxoids through effective kinetic resolution of racemic 4-CF3-β-lactams with baccatins

Chirality

Volumn 9, Issue 5-6, 1997, Pages 487-494

  Ojima, Iwao ^a   Slater, John C ^a  

^a STONY BROOK UNIVERSITY   (United States)

Author keywords

Asymmetri c synthesis; Baecatin; Diastereoselective; Docetaxel; Kinetic resolution; Paclitaxel; Taxoids

Indexed keywords

3' TRIFLUOROMETHYL TAXOID DERIVATIVE; BACCATIN III; BETA LACTAM DERIVATIVE; DOCETAXEL; PACLITAXEL; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CHEMICAL REACTION KINETICS; DRUG STRUCTURE; DRUG SYNTHESIS; ENANTIOMER; HUMAN; HUMAN CELL; ISOMER; PRIORITY JOURNAL; RACEMIC MIXTURE; STEREOCHEMISTRY;

ALKALOIDS; ANTINEOPLASTIC AGENTS; BETA-LACTAMS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; INDICATORS AND REAGENTS; KINETICS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PACLITAXEL; STEREOISOMERISM;

EID: 0030931405     PISSN: 08990042     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1520-636X(1997)9:5/6<487::AID-CHIR15>3.0.CO;2-K     Document Type: Article

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