메뉴 건너뛰기




Volumn 204, Issue 3, 2005, Pages 881-888

Docosahexaenoic acid induces apoptosis in proliferating human endothelial cells

Author keywords

[No Author keywords available]

Indexed keywords

ARACHIDONIC ACID; DNA; DOCOSAHEXAENOIC ACID; MATRIX METALLOPROTEINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; OMEGA 3 FATTY ACID; OMEGA 6 FATTY ACID; POLYUNSATURATED FATTY ACID; PROTEIN P53; REACTIVE OXYGEN METABOLITE;

EID: 23244465860     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcp.20351     Document Type: Article
Times cited : (55)

References (46)
  • 2
    • 1342268345 scopus 로고    scopus 로고
    • Free fatty acids trigger apoptosis and inhibit cell cycle progression in human vascular endothelial cells
    • Artwohl M, Roden M, Waldhäusl W, Freudenthaler A, Baumgartner-Parzer SM. 2004. Free fatty acids trigger apoptosis and inhibit cell cycle progression in human vascular endothelial cells. FASEB J 18:146-148.
    • (2004) FASEB J , vol.18 , pp. 146-148
    • Artwohl, M.1    Roden, M.2    Waldhäusl, W.3    Freudenthaler, A.4    Baumgartner-Parzer, S.M.5
  • 3
    • 0031282325 scopus 로고    scopus 로고
    • Design of a synthetic Mdm2-binding mini protein that activates the p53 response in vivo
    • Bottger A, Bottger V, Sparks A, Liu WL, Howard SF, Lane DP. 1997. Design of a synthetic Mdm2-binding mini protein that activates the p53 response in vivo. Curr Biol 7:860-869.
    • (1997) Curr Biol , vol.7 , pp. 860-869
    • Bottger, A.1    Bottger, V.2    Sparks, A.3    Liu, W.L.4    Howard, S.F.5    Lane, D.P.6
  • 4
    • 0032496143 scopus 로고    scopus 로고
    • Superoxide in apoptosis. Mitochondrial generation triggered by cytochrome c loss
    • Cai J, Jones DP. 1998. Superoxide in apoptosis. Mitochondrial generation triggered by cytochrome c loss. J Biol Chem 273:11401-11404.
    • (1998) J Biol Chem , vol.273 , pp. 11401-11404
    • Cai, J.1    Jones, D.P.2
  • 5
    • 0037971463 scopus 로고    scopus 로고
    • N-3 polyunsaturated fatty acids and inflammation: From molecular biology to the clinic
    • Calder PC. 2003. N-3 polyunsaturated fatty acids and inflammation: From molecular biology to the clinic. Lipids 38:343-352.
    • (2003) Lipids , vol.38 , pp. 343-352
    • Calder, P.C.1
  • 6
    • 0032473553 scopus 로고    scopus 로고
    • Dietary supplementation with eicosapentaenoic and docosahexaenoic acid inhibits growth of Morris hepatocarcinoma 3924A in rats: Effects on proliferation and apoptosis
    • Calviello G, Palozza P, Piccioni E, Maggiano N, Frattucci A, Franceschelli P, Bartoli GM. 1998. Dietary supplementation with eicosapentaenoic and docosahexaenoic acid inhibits growth of Morris hepatocarcinoma 3924A in rats: Effects on proliferation and apoptosis. Int J Cancer 75:699-705.
    • (1998) Int J Cancer , vol.75 , pp. 699-705
    • Calviello, G.1    Palozza, P.2    Piccioni, E.3    Maggiano, N.4    Frattucci, A.5    Franceschelli, P.6    Bartoli, G.M.7
  • 7
    • 0036905360 scopus 로고    scopus 로고
    • Fatty acid modulation of MCF-7 human breast cancer cell proliferation, apoptosis and differentiation
    • Chamras H, Ardashian A, Heber D, Glaspy JA. 2002. Fatty acid modulation of MCF-7 human breast cancer cell proliferation, apoptosis and differentiation. J Nutr Biochem 13:711-716.
    • (2002) J Nutr Biochem , vol.13 , pp. 711-716
    • Chamras, H.1    Ardashian, A.2    Heber, D.3    Glaspy, J.A.4
  • 8
    • 0033639198 scopus 로고    scopus 로고
    • Docosahexaenoic acid is a potent inducer of apoptosis in HT-29 colon cancer cells
    • Chen ZY, Istfan NW. 2000. Docosahexaenoic acid is a potent inducer of apoptosis in HT-29 colon cancer cells. Prostaglandins Leukot Essent Fatty Acids 63:301-308.
    • (2000) Prostaglandins Leukot Essent Fatty Acids , vol.63 , pp. 301-308
    • Chen, Z.Y.1    Istfan, N.W.2
  • 9
    • 0032786257 scopus 로고    scopus 로고
    • Effects of reduced dietary linoleic acid intake, alone or combined with an algal source of docosahexaenoic acid, on MDA-MB-231 breast cancer cell growth and apoptosis in nude mice
    • Connolly JM, Gilhooly EM, Rose DP. 1999. Effects of reduced dietary linoleic acid intake, alone or combined with an algal source of docosahexaenoic acid, on MDA-MB-231 breast cancer cell growth and apoptosis in nude mice. Nutr Cancer 35:44-49.
    • (1999) Nutr Cancer , vol.35 , pp. 44-49
    • Connolly, J.M.1    Gilhooly, E.M.2    Rose, D.P.3
  • 10
    • 0029744856 scopus 로고    scopus 로고
    • Differential effects of n-6 and n-3 polyunsaturated fatty acids on cell growth and early gene expression in Swiss 3T3 fibroblasts
    • Danesch U, Weber PC, Sellmayer A. 1996. Differential effects of n-6 and n-3 polyunsaturated fatty acids on cell growth and early gene expression in Swiss 3T3 fibroblasts. J Cell Physiol 168:618-624.
    • (1996) J Cell Physiol , vol.168 , pp. 618-624
    • Danesch, U.1    Weber, P.C.2    Sellmayer, A.3
  • 11
    • 0033679198 scopus 로고    scopus 로고
    • Docosahexaenoic acid, a peroxisome proliferator-activated receptor-α ligand, induces apoptosis in vascular smooth muscle cells by stimulation of p38 mitogen-activated protein kinase
    • Diep QN, Touyz RM, Schiffrin EL. 2000. Docosahexaenoic acid, a peroxisome proliferator-activated receptor-α ligand, induces apoptosis in vascular smooth muscle cells by stimulation of p38 mitogen-activated protein kinase. Hypertension 36:851-855.
    • (2000) Hypertension , vol.36 , pp. 851-855
    • Diep, Q.N.1    Touyz, R.M.2    Schiffrin, E.L.3
  • 12
    • 0030934293 scopus 로고    scopus 로고
    • Oxidized low-density lipoprotein induces apoptosis of human endothelial cells by activation of CPP32-like proteases. A mechanistic clue to the 'response to injury' hypothesis
    • Dimmeler S, Haendeler J, Galle J, Zeiher AM. 1997. Oxidized low-density lipoprotein induces apoptosis of human endothelial cells by activation of CPP32-like proteases. A mechanistic clue to the 'response to injury' hypothesis. Circulation 95:1760-1763.
    • (1997) Circulation , vol.95 , pp. 1760-1763
    • Dimmeler, S.1    Haendeler, J.2    Galle, J.3    Zeiher, A.M.4
  • 13
    • 0033916920 scopus 로고    scopus 로고
    • Pyrrolidine dithiocarbamate-induced apoptosis depends on cell type, density, and the presence of Cu(2+) and Zn(2+)
    • Erl W, Weber C, Hansson GK. 2000. Pyrrolidine dithiocarbamate-induced apoptosis depends on cell type, density, and the presence of Cu(2+) and Zn(2+). Am J Physiol Cell Physiol 278:C1116-C1125.
    • (2000) Am J Physiol Cell Physiol , vol.278
    • Erl, W.1    Weber, C.2    Hansson, G.K.3
  • 14
    • 1642554781 scopus 로고    scopus 로고
    • Cyclopentenone prostaglandins induce endothelial cell apoptosis independent of the peroxisome proliferator-activated receptor-gamma
    • Erl W, Weber C, Zernecke A, Neuzil J, Vosseler CA, Kim HJ, Weber PC. 2004. Cyclopentenone prostaglandins induce endothelial cell apoptosis independent of the peroxisome proliferator-activated receptor-gamma. Eur J Immunol 34:241-250.
    • (2004) Eur J Immunol , vol.34 , pp. 241-250
    • Erl, W.1    Weber, C.2    Zernecke, A.3    Neuzil, J.4    Vosseler, C.A.5    Kim, H.J.6    Weber, P.C.7
  • 15
    • 0037377376 scopus 로고    scopus 로고
    • Angiogenesis: Basic pathophysiology and implications for disease
    • Felmeden DC, Blann AD, Lip GY. 2003. Angiogenesis: Basic pathophysiology and implications for disease. Eur Heart J 24:586-603.
    • (2003) Eur Heart J , vol.24 , pp. 586-603
    • Felmeden, D.C.1    Blann, A.D.2    Lip, G.Y.3
  • 16
    • 0036478970 scopus 로고    scopus 로고
    • Mitochondrial reactive oxygen species in cell death signaling
    • Fleury C, Mignotte B, Vayssiere JL. 2002. Mitochondrial reactive oxygen species in cell death signaling. Biochimie 84:131-141.
    • (2002) Biochimie , vol.84 , pp. 131-141
    • Fleury, C.1    Mignotte, B.2    Vayssiere, J.L.3
  • 17
    • 0345712345 scopus 로고    scopus 로고
    • Dietary n-3 polyunsaturated fatty acids and oxidants increase rat mammary tumor sensitivity to epirubicin without change in cardiac toxicity
    • Germain E, Lavandier F, Chajes V, Schubnel V, Bonnet P, Lhuillery C, Bougnoux P. 1999. Dietary n-3 polyunsaturated fatty acids and oxidants increase rat mammary tumor sensitivity to epirubicin without change in cardiac toxicity. Lipids 34:8203.
    • (1999) Lipids , vol.34 , pp. 8203
    • Germain, E.1    Lavandier, F.2    Chajes, V.3    Schubnel, V.4    Bonnet, P.5    Lhuillery, C.6    Bougnoux, P.7
  • 20
    • 0037379690 scopus 로고    scopus 로고
    • Resveratrol increases serine15-phosphorylated but transcriptionally impaired p53 and induces a reversible DNA replication block in serum-activated vascular smooth muscle cells
    • Haider UG, Sorescu D, Griendling KK, Vollmar AM, Dirsch VM. 2003. Resveratrol increases serine15-phosphorylated but transcriptionally impaired p53 and induces a reversible DNA replication block in serum-activated vascular smooth muscle cells. Mol Pharmacol 63:925-932.
    • (2003) Mol Pharmacol , vol.63 , pp. 925-932
    • Haider, U.G.1    Sorescu, D.2    Griendling, K.K.3    Vollmar, A.M.4    Dirsch, V.M.5
  • 22
    • 0033152949 scopus 로고    scopus 로고
    • Resveratrol increases nitric oxide synthase, induces accumulation of p53 and p21(WAF1/CIP1), and suppresses cultured bovine pulmonary artery endothelial cell proliferation by perturbing progression through S and G2
    • Hsieh TC, Juan G, Darzynkiewicz Z, Wu JM. 1999. Resveratrol increases nitric oxide synthase, induces accumulation of p53 and p21(WAF1/CIP1), and suppresses cultured bovine pulmonary artery endothelial cell proliferation by perturbing progression through S and G2. Cancer Res 59:2596-2601.
    • (1999) Cancer Res , vol.59 , pp. 2596-2601
    • Hsieh, T.C.1    Juan, G.2    Darzynkiewicz, Z.3    Wu, J.M.4
  • 23
    • 0034947516 scopus 로고    scopus 로고
    • Effect of omega-3 fatty acid (docosahexanoic acid) on BRCAl gene expression and growth in MCF-7 cell line
    • Kachhap SK, Dange PP, Santani RH, Sawant SS, Ghosh SN. 2001. Effect of omega-3 fatty acid (docosahexanoic acid) on BRCAl gene expression and growth in MCF-7 cell line. Cancer Biother Radiopharm 16:257-263.
    • (2001) Cancer Biother Radiopharm , vol.16 , pp. 257-263
    • Kachhap, S.K.1    Dange, P.P.2    Santani, R.H.3    Sawant, S.S.4    Ghosh, S.N.5
  • 24
    • 0036235809 scopus 로고    scopus 로고
    • Inhibition of cell proliferation and induction of apoptosis by Helicobacter pylori through increased phosphorylated p53, p21 and Bax expression in endothelial cells
    • Kurosawa A, Miwa H, Hirose M, Tsune I, Nagahara A, Sato N. 2002. Inhibition of cell proliferation and induction of apoptosis by Helicobacter pylori through increased phosphorylated p53, p21 and Bax expression in endothelial cells. J Med Microbiol 51:385-391.
    • (2002) J Med Microbiol , vol.51 , pp. 385-391
    • Kurosawa, A.1    Miwa, H.2    Hirose, M.3    Tsune, I.4    Nagahara, A.5    Sato, N.6
  • 25
    • 3042767902 scopus 로고    scopus 로고
    • Dietary long-chain n-3 fattv acids for the prevention of cancer: A review of potential mechanisms
    • Larsson SC, Kumlin M, Ingelman-Sundberg M, WoIk A. 2004. Dietary long-chain n-3 fattv acids for the prevention of cancer: A review of potential mechanisms. Am J Clin Nutr 79:935-945.
    • (2004) Am J Clin Nutr , vol.79 , pp. 935-945
    • Larsson, S.C.1    Kumlin, M.2    Ingelman-Sundberg, M.3    Woik, A.4
  • 26
    • 0023831640 scopus 로고
    • Cardiovascular effects of n-3 fatty acids
    • Leaf A, Weber PC. 1988. Cardiovascular effects of n-3 fatty acids. N Engl J Med 318:549-557.
    • (1988) N Engl J Med , vol.318 , pp. 549-557
    • Leaf, A.1    Weber, P.C.2
  • 27
    • 0036468287 scopus 로고    scopus 로고
    • Cyclooxygenase-2 inhibition by celecoxib reduces proliferation and induces apoptosis in angiogenic endothelial cells in vivo
    • Leahy KM, Ornberg RL, Wang Y, Zweifel BS, Koki AT, Masferrer JL. 2002. Cyclooxygenase-2 inhibition by celecoxib reduces proliferation and induces apoptosis in angiogenic endothelial cells in vivo. Cancer Res 62:625-631.
    • (2002) Cancer Res , vol.62 , pp. 625-631
    • Leahy, K.M.1    Ornberg, R.L.2    Wang, Y.3    Zweifel, B.S.4    Koki, A.T.5    Masferrer, J.L.6
  • 28
    • 0020664995 scopus 로고
    • Platelet function, thromboxane formation and blood pressure control during supplementation of the Western diet with cod liver oil
    • Lorenz R, Spengler U, Fischer S, Duhm J, Weber PC. 1983. Platelet function, thromboxane formation and blood pressure control during supplementation of the Western diet with cod liver oil. Circulation 67:504-511.
    • (1983) Circulation , vol.67 , pp. 504-511
    • Lorenz, R.1    Spengler, U.2    Fischer, S.3    Duhm, J.4    Weber, P.C.5
  • 29
    • 0030610565 scopus 로고    scopus 로고
    • The CDK7-cycH-p36 complex of transcription factor IIH phosphorylates p53, enhancing its sequence-specific DNA binding activity in vitro
    • Lu H, Fisher RP, Bailey P, Levine AJ. 1997. The CDK7-cycH-p36 complex of transcription factor IIH phosphorylates p53, enhancing its sequence-specific DNA binding activity in vitro. Mol Cell Biol 17:5923-5934.
    • (1997) Mol Cell Biol , vol.17 , pp. 5923-5934
    • Lu, H.1    Fisher, R.P.2    Bailey, P.3    Levine, A.J.4
  • 30
    • 0344183101 scopus 로고    scopus 로고
    • Cellular enrichment with polyunsaturated fatty acids induces an oxidative stress and activates the transcription factors AP1 and NFkappaB
    • Maziere C, Conte MA, Degonville J, Ali D, Maziere JC. 1999. Cellular enrichment with polyunsaturated fatty acids induces an oxidative stress and activates the transcription factors AP1 and NFkappaB. Biochem Biophys Res Commun 265:116-122.
    • (1999) Biochem Biophys Res Commun , vol.265 , pp. 116-122
    • Maziere, C.1    Conte, M.A.2    Degonville, J.3    Ali, D.4    Maziere, J.C.5
  • 32
    • 0041767435 scopus 로고    scopus 로고
    • Endothelial cell functions
    • Michiels C. 2003. Endothelial cell functions. J Cell Physiol 196:430-443.
    • (2003) J Cell Physiol , vol.196 , pp. 430-443
    • Michiels, C.1
  • 33
    • 0033528660 scopus 로고    scopus 로고
    • Angiogenesis inhibitors endostatin or TNP-470 reduce intimai neovascularization and plaque growth in apolipoprotein E-deficient mice
    • Moulton KS, Heller E, Konerding MA, Flynn E, Palinski W, Folkman J. 1999. Angiogenesis inhibitors endostatin or TNP-470 reduce intimai neovascularization and plaque growth in apolipoprotein E-deficient mice. Circulation 99:1726-1732.
    • (1999) Circulation , vol.99 , pp. 1726-1732
    • Moulton, K.S.1    Heller, E.2    Konerding, M.A.3    Flynn, E.4    Palinski, W.5    Folkman, J.6
  • 35
    • 0032745478 scopus 로고    scopus 로고
    • Eicosapentaenoic acid and docosahexaenoic acid selectively attenuate U46619-induced smooth muscle cell proliferation
    • Pakala R, Pakala R, Benedict C. 1999. Eicosapentaenoic acid and docosahexaenoic acid selectively attenuate U46619-induced smooth muscle cell proliferation. Lipids 34:915-920.
    • (1999) Lipids , vol.34 , pp. 915-920
    • Pakala, R.1    Pakala, R.2    Benedict, C.3
  • 36
    • 0032931517 scopus 로고    scopus 로고
    • The p53 pathway
    • Prives C, Hall PA. 1999. The p53 pathway. J Pathol 187:112-126.
    • (1999) J Pathol , vol.187 , pp. 112-126
    • Prives, C.1    Hall, P.A.2
  • 37
    • 0033228435 scopus 로고    scopus 로고
    • Antiangiogenicity of docosahexaenoic acid and its role in the suppression of breast cancer cell growth in nude mice
    • Rose DP, Connolly JM. 1999a. Antiangiogenicity of docosahexaenoic acid and its role in the suppression of breast cancer cell growth in nude mice. Int J Oncol 15:1011-1015.
    • (1999) Int J Oncol , vol.15 , pp. 1011-1015
    • Rose, D.P.1    Connolly, J.M.2
  • 38
    • 0032860560 scopus 로고    scopus 로고
    • Omega-3 fattv acids as cancer chemopreventive agents
    • Rose DP, Connolly JM. 1999b. Omega-3 fattv acids as cancer chemopreventive agents. Pharmacol Ther 83:217-244.
    • (1999) Pharmacol Ther , vol.83 , pp. 217-244
    • Rose, D.P.1    Connolly, J.M.2
  • 39
    • 0030667702 scopus 로고    scopus 로고
    • DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2
    • Shieh SY, Ikeda M, Taya Y, Prives C. 1997. DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2. Cell 91:325-334.
    • (1997) Cell , vol.91 , pp. 325-334
    • Shieh, S.Y.1    Ikeda, M.2    Taya, Y.3    Prives, C.4
  • 40
    • 0018890839 scopus 로고
    • Platelet-membrane fatty acids, platelet aggregation, and thromboxane formation during a mackerel diet
    • Siess W, Roth P, Scherer B, Kurzmann I, Bohlig B, Weber PC. 1980. Platelet-membrane fatty acids, platelet aggregation, and thromboxane formation during a mackerel diet. Lancet 1:441-444.
    • (1980) Lancet , vol.1 , pp. 441-444
    • Siess, W.1    Roth, P.2    Scherer, B.3    Kurzmann, I.4    Bohlig, B.5    Weber, P.C.6
  • 42
    • 0036119155 scopus 로고    scopus 로고
    • Lysophosphatidylcholine induces apoptosis in human endothelial cells through a p38-mitogen-activated protein kinase-dependent mechanism
    • Takahashi M, Okazaki H, Ogata Y, Takeuchi K, Ikeda U, Shimada K. 2002. Lysophosphatidylcholine induces apoptosis in human endothelial cells through a p38-mitogen-activated protein kinase-dependent mechanism. Atherosclerosis 161:387-394.
    • (2002) Atherosclerosis , vol.161 , pp. 387-394
    • Takahashi, M.1    Okazaki, H.2    Ogata, Y.3    Takeuchi, K.4    Ikeda, U.5    Shimada, K.6
  • 44
    • 2342562556 scopus 로고    scopus 로고
    • Mitogen-activated protein kinases in apoptosis regulation
    • Wada T, Penninger JM. 2004. Mitogen-activated protein kinases in apoptosis regulation. Oncogene 23:2838-2849.
    • (2004) Oncogene , vol.23 , pp. 2838-2849
    • Wada, T.1    Penninger, J.M.2
  • 45
    • 0029003061 scopus 로고
    • 1 cyclin-dependent kinases
    • 1 cyclin-dependent kinases. Nature 376:88-91.
    • (1995) Nature , vol.376 , pp. 88-91
    • Wang, Y.1    Prives, C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.