메뉴 건너뛰기




Volumn 19, Issue 2, 2005, Pages 95-99

Gender differences in Alzheimer disease: The role of luteinizing hormone in disease pathogenesis

Author keywords

[No Author keywords available]

Indexed keywords

GONADORELIN ANTAGONIST; GONADOTROPIN; LEUPRORELIN; LUTEINIZING HORMONE;

EID: 23044514634     PISSN: 08930341     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.wad.0000165512.90864.3f     Document Type: Review
Times cited : (30)

References (60)
  • 1
    • 23044496541 scopus 로고    scopus 로고
    • note
    • Deleted in proof.
  • 2
    • 23044502064 scopus 로고    scopus 로고
    • note
    • Deleted in proof.
  • 3
    • 0031038918 scopus 로고    scopus 로고
    • Alzheimer's disease: Genotypes, phenotypes and treatments
    • Selkoe DJ. Alzheimer's disease: genotypes, phenotypes and treatments. Science. 1997;275:630-631.
    • (1997) Science , vol.275 , pp. 630-631
    • Selkoe, D.J.1
  • 4
    • 0030611097 scopus 로고    scopus 로고
    • Aβ deposition is associated with neuropil changes, but not with overt neuronal loss in the human amyloid precursor protein V717F (PDAPP) transgenic mouse
    • Irizarry MC, Soriano F, McNamara M, et al. Aβ deposition is associated with neuropil changes, but not with overt neuronal loss in the human amyloid precursor protein V717F (PDAPP) transgenic mouse. J Neurosci. 1997;17:7053-7059.
    • (1997) J Neurosci , vol.17 , pp. 7053-7059
    • Irizarry, M.C.1    Soriano, F.2    McNamara, M.3
  • 7
    • 0035997240 scopus 로고    scopus 로고
    • The state versus amyloid-β: The trial of the most wanted criminal in Alzheimer disease
    • Rottkamp CA, Atwood CS, Joseph JA, et al. The state versus amyloid-β: the trial of the most wanted criminal in Alzheimer disease. Peptides. 2002;23:1333-1341.
    • (2002) Peptides , vol.23 , pp. 1333-1341
    • Rottkamp, C.A.1    Atwood, C.S.2    Joseph, J.A.3
  • 8
    • 3242737470 scopus 로고    scopus 로고
    • Challenging the amyloid cascade hypothesis: Senile plaques and amyloid-beta as protective adaptations to Alzheimer disease
    • Lee HG, Casadesus G, Zhu X, et al. Challenging the amyloid cascade hypothesis: senile plaques and amyloid-beta as protective adaptations to Alzheimer disease. Ann N Y Acad Sci. 2004;1019:1-4.
    • (2004) Ann N Y Acad Sci , vol.1019 , pp. 1-4
    • Lee, H.G.1    Casadesus, G.2    Zhu, X.3
  • 9
    • 0033301774 scopus 로고    scopus 로고
    • Elevated levels of tau in cerebrospinal fluid: Implications for the antemortem diagnosis of Alzheimer's disease elevated levels of tau in cerebrospinal fluid
    • Trojanowski JQ, Clark CM, Arai H, et al. Elevated levels of tau in cerebrospinal fluid: implications for the antemortem diagnosis of Alzheimer's disease elevated levels of tau in cerebrospinal fluid. J Alzheimers Dis. 1999;1:297-305.
    • (1999) J Alzheimers Dis , vol.1 , pp. 297-305
    • Trojanowski, J.Q.1    Clark, C.M.2    Arai, H.3
  • 10
    • 0034733799 scopus 로고    scopus 로고
    • Tau aggregation into fibrillar polymers: Taupathies
    • Avila J. Tau aggregation into fibrillar polymers: taupathies. FEBS Lett. 2000;476:89-92.
    • (2000) FEBS Lett , vol.476 , pp. 89-92
    • Avila, J.1
  • 11
    • 0036770144 scopus 로고    scopus 로고
    • The role of mitogen-activated protein kinase pathways in Alzheimer disease
    • Zhu X, Perry G, Raina AK, et al. The role of mitogen-activated protein kinase pathways in Alzheimer disease. Neurosignals. 2002;11:270-281.
    • (2002) Neurosignals , vol.11 , pp. 270-281
    • Zhu, X.1    Perry, G.2    Raina, A.K.3
  • 12
    • 0032229327 scopus 로고    scopus 로고
    • Reactive oxygen species mediate cellular damage in Alzheimer disease
    • Perry G, Castellani RJ, Hirai K, et al. Reactive oxygen species mediate cellular damage in Alzheimer disease. J Alzheimers Dis. 1998;1:45-55.
    • (1998) J Alzheimers Dis , vol.1 , pp. 45-55
    • Perry, G.1    Castellani, R.J.2    Hirai, K.3
  • 13
    • 0036113819 scopus 로고    scopus 로고
    • The role of iron and copper in the aetiology of neurodegenerative disorders: Therapeutic implications
    • Perry G, Sayre LM, Atwood CS, et al. The role of iron and copper in the aetiology of neurodegenerative disorders: therapeutic implications. CNS Drugs. 2002;16:339-352.
    • (2002) CNS Drugs , vol.16 , pp. 339-352
    • Perry, G.1    Sayre, L.M.2    Atwood, C.S.3
  • 14
    • 0002451682 scopus 로고    scopus 로고
    • Neuroinflammatory responses in the Alzheimer's disease brain promote the oxidative post-translational modification of amyloid deposits
    • Iqbal K, Sisoda SS, Winbald B, eds. UK: John Wiley & Sons, Ltd
    • Atwood CS, Huang X, Moir RD, et al. Neuroinflammatory responses in the Alzheimer's disease brain promote the oxidative post-translational modification of amyloid deposits. In: Iqbal K, Sisoda SS, Winbald B, eds. Alzheimer's Disease: Advances in Etiology, Pathogenesis and Therapeutics. UK: John Wiley & Sons, Ltd; 2001:341-361.
    • (2001) Alzheimer's Disease: Advances in Etiology, Pathogenesis and Therapeutics , pp. 341-361
    • Atwood, C.S.1    Huang, X.2    Moir, R.D.3
  • 15
    • 0028603650 scopus 로고
    • Incidence of dementia and Alzheimer's disease in elderly community residents of south-western France
    • Letenneur L, Commenges D, Dartigues JF, et al. Incidence of dementia and Alzheimer's disease in elderly community residents of south-western France. Int J Epidemiol. 1994;26:1256-1261.
    • (1994) Int J Epidemiol , vol.26 , pp. 1256-1261
    • Letenneur, L.1    Commenges, D.2    Dartigues, J.F.3
  • 16
    • 0031024278 scopus 로고    scopus 로고
    • Very old women at highest risk of dementia and Alzheimer's disease: Incidence data from the Kungsholmen Project, Stockholm
    • Fratiglioni L, Viitanen M, Strauss EV, et al. Very old women at highest risk of dementia and Alzheimer's disease: Incidence data from the Kungsholmen Project, Stockholm. Neurology. 1997;48:132-138.
    • (1997) Neurology , vol.48 , pp. 132-138
    • Fratiglioni, L.1    Viitanen, M.2    Strauss, E.V.3
  • 17
    • 0023628422 scopus 로고
    • The prevalence of dementia: A quantitative integration of the literature
    • Jorm AF, Korten AE, Henderson AS. The prevalence of dementia: a quantitative integration of the literature. Acta Psychiatr Scand. 1987;76:465-479.
    • (1987) Acta Psychiatr Scand , vol.76 , pp. 465-479
    • Jorm, A.F.1    Korten, A.E.2    Henderson, A.S.3
  • 18
    • 0023853488 scopus 로고
    • Familial aggregation in Alzheimer's disease: Comparison of risk among relatives of early- and late-onset cases, and among male and female relatives in successive generations
    • Breitner JCS, Silverman JM, Mohs RC, et al. Familial aggregation in Alzheimer's disease: Comparison of risk among relatives of early- and late-onset cases, and among male and female relatives in successive generations. Neurology. 1988;38:207-212.
    • (1988) Neurology , vol.38 , pp. 207-212
    • Breitner, J.C.S.1    Silverman, J.M.2    Mohs, R.C.3
  • 19
    • 0025989415 scopus 로고
    • Frequency and distribution of Alzheimer's disease in Europe: A collaborative study of 1980-1990 prevalence findings
    • The EURODEM-Prevalence Research Group
    • Rocca WA, Hofman A, Brayne C, et al. Frequency and distribution of Alzheimer's disease in Europe: a collaborative study of 1980-1990 prevalence findings. The EURODEM-Prevalence Research Group. Ann Neurol. 1991;30:381-390.
    • (1991) Ann Neurol , vol.30 , pp. 381-390
    • Rocca, W.A.1    Hofman, A.2    Brayne, C.3
  • 20
    • 0027447726 scopus 로고
    • Epidemiology of Alzheimer's presenile dementia in Scotland, 1974-88
    • McGonigal G, Thamas B, McQuade C, et al. Epidemiology of Alzheimer's presenile dementia in Scotland, 1974-88. BMJ. 1993;306:680-683.
    • (1993) BMJ , vol.306 , pp. 680-683
    • McGonigal, G.1    Thamas, B.2    McQuade, C.3
  • 21
    • 0031720801 scopus 로고    scopus 로고
    • The incidence of dementia: A meta-analysis
    • Jorm AF, Jolley D. The incidence of dementia: a meta-analysis. Neurology. 1998;51:728-733.
    • (1998) Neurology , vol.51 , pp. 728-733
    • Jorm, A.F.1    Jolley, D.2
  • 22
    • 0034700965 scopus 로고    scopus 로고
    • Endogenous estrogen levels and Alzheimer's disease among postmenopausal women
    • Manly JJ, Merchant CA, Jacobs DM, et al. Endogenous estrogen levels and Alzheimer's disease among postmenopausal women. Neurology. 2000;54:833-837.
    • (2000) Neurology , vol.54 , pp. 833-837
    • Manly, J.J.1    Merchant, C.A.2    Jacobs, D.M.3
  • 23
    • 0028086440 scopus 로고
    • Estrogen replacement therapy in older women. Comparisons between Alzheimer's disease cases and nondemented control subjects
    • Henderson VW, Paganini-Hill A, Emanuel CK, et al. Estrogen replacement therapy in older women. Comparisons between Alzheimer's disease cases and nondemented control subjects. Arch Neurol. 1994;51:896-900.
    • (1994) Arch Neurol , vol.51 , pp. 896-900
    • Henderson, V.W.1    Paganini-Hill, A.2    Emanuel, C.K.3
  • 24
    • 0030591669 scopus 로고    scopus 로고
    • Effect of oestrogen during menopause on risk and age at onset of Alzheimer's disease
    • Tang MX, Jacobs D, Stern Y, et al. Effect of oestrogen during menopause on risk and age at onset of Alzheimer's disease. Lancet. 1996;348:429-432.
    • (1996) Lancet , vol.348 , pp. 429-432
    • Tang, M.X.1    Jacobs, D.2    Stern, Y.3
  • 25
    • 0030748719 scopus 로고    scopus 로고
    • A prospective study of estrogen replacement therapy and the risk of developing Alzheimer's disease: The Baltimore Longitudinal Study of Aging
    • Kawas C, Resnick S, Morrison A, et al. A prospective study of estrogen replacement therapy and the risk of developing Alzheimer's disease: the Baltimore Longitudinal Study of Aging. Neurology. 1997;48:1517-1521.
    • (1997) Neurology , vol.48 , pp. 1517-1521
    • Kawas, C.1    Resnick, S.2    Morrison, A.3
  • 26
    • 0037032405 scopus 로고    scopus 로고
    • Hormone therapy and risk of Alzheimer disease: A critical time
    • Resnick SM, Henderson VW. Hormone therapy and risk of Alzheimer disease: a critical time. JAMA. 2002;288:2170-2172.
    • (2002) JAMA , vol.288 , pp. 2170-2172
    • Resnick, S.M.1    Henderson, V.W.2
  • 27
    • 0038386058 scopus 로고    scopus 로고
    • Estrogen plus progestin and the incidence of dementia and mild cognitive impairment in postmenopausal women. The Women's Health Initiative memory study: A randomized controlled trial
    • Shumaker SA, Legault C, Rapp SR, et al. Estrogen plus progestin and the incidence of dementia and mild cognitive impairment in postmenopausal women. The Women's Health Initiative memory study: a randomized controlled trial. JAMA. 2003;289:2651-2662.
    • (2003) JAMA , vol.289 , pp. 2651-2662
    • Shumaker, S.A.1    Legault, C.2    Rapp, S.R.3
  • 28
    • 0030609088 scopus 로고    scopus 로고
    • Effects of 17β-estradiol on glucose transporter 1 expression and endothelial cell survival following focal ischemia in rat
    • Shi J, Zhang YQ, Simpkins JW. Effects of 17β-estradiol on glucose transporter 1 expression and endothelial cell survival following focal ischemia in rat. Exp Brain Res. 1997;117:200-206.
    • (1997) Exp Brain Res , vol.117 , pp. 200-206
    • Shi, J.1    Zhang, Y.Q.2    Simpkins, J.W.3
  • 29
    • 0343673804 scopus 로고    scopus 로고
    • Fiber from whole grains, but not refined grains, is inversely associated with all-cause mortality in older women: The Iowa women's health study
    • Jacobs DR, Pereira MA, Meyer KA, et al. Fiber from whole grains, but not refined grains, is inversely associated with all-cause mortality in older women: the Iowa women's health study. J Am Coll Nutr. 2000;19:326S-330S.
    • (2000) J Am Coll Nutr , vol.19
    • Jacobs, D.R.1    Pereira, M.A.2    Meyer, K.A.3
  • 31
    • 0037269433 scopus 로고    scopus 로고
    • Measuring serum oestradiol in women with Alzheimer's disease: The importance of the sensitivity of the assay method
    • Hogervorst E, Williams J, Combrinck M, et al. Measuring serum oestradiol in women with Alzheimer's disease: the importance of the sensitivity of the assay method. Eur J Endocrinol. 2003;148:67-72.
    • (2003) Eur J Endocrinol , vol.148 , pp. 67-72
    • Hogervorst, E.1    Williams, J.2    Combrinck, M.3
  • 32
    • 0038724280 scopus 로고    scopus 로고
    • Effect of estrogen plus progestin on global cognitive function in postmenopausal women: The Women's Health Initiative Memory Study: A randomized controlled trial
    • WHIMS Investigators
    • Rapp SR, Espeland MA, Shumaker SA, et al. WHIMS Investigators. Effect of estrogen plus progestin on global cognitive function in postmenopausal women: the Women's Health Initiative Memory Study: a randomized controlled trial. JAMA. 2003;20:2663-2672.
    • (2003) JAMA , vol.20 , pp. 2663-2672
    • Rapp, S.R.1    Espeland, M.A.2    Shumaker, S.A.3
  • 33
    • 0031948289 scopus 로고    scopus 로고
    • Earlier onset of Alzheimer's disease in men with Down syndrome
    • Schupf N, Kapell D, Nightingale B, et al. Earlier onset of Alzheimer's disease in men with Down syndrome. Neurology. 1998;50:991-995.
    • (1998) Neurology , vol.50 , pp. 991-995
    • Schupf, N.1    Kapell, D.2    Nightingale, B.3
  • 34
    • 0031054674 scopus 로고    scopus 로고
    • Brain infarction and the clinical expression of Alzheimer disease. The Nun Study
    • Snowdon DA, Greiner LH, Mortimer JA, et al. Brain infarction and the clinical expression of Alzheimer disease. The Nun Study. JAMA. 1997;277:813-817.
    • (1997) JAMA , vol.277 , pp. 813-817
    • Snowdon, D.A.1    Greiner, L.H.2    Mortimer, J.A.3
  • 36
    • 0036790467 scopus 로고    scopus 로고
    • Activins, inhibins, and follistatins: From endocrinology to signaling. A paradigm for the new millennium
    • Welt C, Sidis Y, Keutmann H, et al. Activins, inhibins, and follistatins: from endocrinology to signaling. A paradigm for the new millennium. Exp Biol Med. 2002;227:724-752.
    • (2002) Exp Biol Med , vol.227 , pp. 724-752
    • Welt, C.1    Sidis, Y.2    Keutmann, H.3
  • 37
    • 0027375544 scopus 로고
    • The control of gonadotropin secretion by ovarian steroids
    • Couzinet B, Schaison G. The control of gonadotropin secretion by ovarian steroids. Hum Reprod Suppl. 1993;2:97-101.
    • (1993) Hum Reprod Suppl , vol.2 , pp. 97-101
    • Couzinet, B.1    Schaison, G.2
  • 38
    • 0017168921 scopus 로고
    • Hormonal profiles after the menopause
    • Chakravarti S, Collins WP, Forecast JD, et al. Hormonal profiles after the menopause. BMJ. 1976;2:784-787.
    • (1976) BMJ , vol.2 , pp. 784-787
    • Chakravarti, S.1    Collins, W.P.2    Forecast, J.D.3
  • 39
    • 0021123879 scopus 로고
    • Leydig cell numbers, daily sperm production, and serum gonadotropin levels in aging men
    • Neaves WB, Johnson L, Porter JC, et al. Leydig cell numbers, daily sperm production, and serum gonadotropin levels in aging men. J Clin Endocrinol Metab. 1984;59:756-763.
    • (1984) J Clin Endocrinol Metab , vol.59 , pp. 756-763
    • Neaves, W.B.1    Johnson, L.2    Porter, J.C.3
  • 40
    • 0027210341 scopus 로고
    • Novel expression of human chorionic gonadotropin/luteinizing hormone receptor gene in brain
    • Lei ZM, Rao CV, Kornyei JL, et al. Novel expression of human chorionic gonadotropin/luteinizing hormone receptor gene in brain. Endocrinology. 1993;132:2262-2270.
    • (1993) Endocrinology , vol.132 , pp. 2262-2270
    • Lei, Z.M.1    Rao, C.V.2    Kornyei, J.L.3
  • 41
    • 0037010296 scopus 로고    scopus 로고
    • Elevated luteinizing hormone expression colocalizes with neurons vulnerable to Alzheimer's disease pathology
    • Bowen RL, Smith MA, Harris PLR, et al. Elevated luteinizing hormone expression colocalizes with neurons vulnerable to Alzheimer's disease pathology. J Neurosci Res. 2002;70:514-518.
    • (2002) J Neurosci Res , vol.70 , pp. 514-518
    • Bowen, R.L.1    Smith, M.A.2    Harris, P.L.R.3
  • 42
    • 0034661784 scopus 로고    scopus 로고
    • Cyclin' toward dementia: Cell cycle abnormalities and abortive oncogenesis in Alzheimer disease
    • Raina AK, Zhu X, Rottkamp CA, et al. Cyclin' toward dementia: cell cycle abnormalities and abortive oncogenesis in Alzheimer disease. J Neurosci Res. 2000;61:128-133.
    • (2000) J Neurosci Res , vol.61 , pp. 128-133
    • Raina, A.K.1    Zhu, X.2    Rottkamp, C.A.3
  • 43
    • 0036592637 scopus 로고    scopus 로고
    • Cell cycle proteins in Alzheimer's disease: Plenty of wheels but no cycle
    • Bowser R, Smith MA. Cell cycle proteins in Alzheimer's disease: plenty of wheels but no cycle. J Alzheimers Dis. 2002;4:249-254.
    • (2002) J Alzheimers Dis , vol.4 , pp. 249-254
    • Bowser, R.1    Smith, M.A.2
  • 44
    • 24344482275 scopus 로고    scopus 로고
    • Alzheimer disease - A new beginning, or a final exit?
    • Copani A, Nicoletti F, eds. TX: Landes Bioscience
    • Obrenovich ME, Raina A, Ogawa O, et al. Alzheimer disease-a new beginning, or a final exit? In: Copani A, Nicoletti F, eds. The Cell Cycle and Neuronal Cell Death. TX: Landes Bioscience; 2003.
    • (2003) The Cell Cycle and Neuronal Cell Death
    • Obrenovich, M.E.1    Raina, A.2    Ogawa, O.3
  • 45
    • 0030921323 scopus 로고    scopus 로고
    • Abnormal expression of the cell cycle regulators p16 and CDK4 in Alzheimer's disease
    • McShea A, Harris PLR, Webster KR, et al. Abnormal expression of the cell cycle regulators p16 and CDK4 in Alzheimer's disease. Am J Pathol. 1997;150:1933-1939.
    • (1997) Am J Pathol , vol.150 , pp. 1933-1939
    • McShea, A.1    Harris, P.L.R.2    Webster, K.R.3
  • 46
    • 0035341254 scopus 로고    scopus 로고
    • Mitochondrial abnormalities in Alzheimer's disease
    • Hirai K, Aliev G, Nunomura A, et al. Mitochondrial abnormalities in Alzheimer's disease. J Neurosci. 2001;21:3017-3023.
    • (2001) J Neurosci , vol.21 , pp. 3017-3023
    • Hirai, K.1    Aliev, G.2    Nunomura, A.3
  • 47
    • 0033782845 scopus 로고    scopus 로고
    • Activation of p38 kinase links tau phosphorylation, oxidative stress, and cell cycle-related events in Alzheimer disease
    • Zhu X, Rottkamp CA, Boux H, et al. Activation of p38 kinase links tau phosphorylation, oxidative stress, and cell cycle-related events in Alzheimer disease. J Neuropathol Exp Neurol. 2000;59:880-888.
    • (2000) J Neuropathol Exp Neurol , vol.59 , pp. 880-888
    • Zhu, X.1    Rottkamp, C.A.2    Boux, H.3
  • 48
    • 0033516947 scopus 로고    scopus 로고
    • Activation of neuronal extracellular receptor kinase (ERK) in Alzheimer disease links oxidative stress to abnormal phosphorylation
    • Perry G, Roder H, Nunomura A, et al. Activation of neuronal extracellular receptor kinase (ERK) in Alzheimer disease links oxidative stress to abnormal phosphorylation. Neuroreport. 1999;10:2411-2415.
    • (1999) Neuroreport , vol.10 , pp. 2411-2415
    • Perry, G.1    Roder, H.2    Nunomura, A.3
  • 49
    • 0034797352 scopus 로고    scopus 로고
    • Differential activation of neuronal ERK, JNK/SAPK and p38 in Alzheimer disease: The "two hit" hypothesis
    • Zhu X, Castellani RJ, Takeda A, et al. Differential activation of neuronal ERK, JNK/SAPK and p38 in Alzheimer disease: the "two hit" hypothesis. Mech Ageing Dev. 2001;123:39-46.
    • (2001) Mech Ageing Dev , vol.123 , pp. 39-46
    • Zhu, X.1    Castellani, R.J.2    Takeda, A.3
  • 50
    • 0036173664 scopus 로고    scopus 로고
    • Activation of MAPK cascades by GnRH: ERK and Jun N-terminal kinase are involved in basal and GnRH-stimulated activity of the glycoprotein hormone LHβ-subunit promoter
    • Harris D, Bonfil D, Chuderland D, et al. Activation of MAPK cascades by GnRH: ERK and Jun N-terminal kinase are involved in basal and GnRH-stimulated activity of the glycoprotein hormone LHβ-subunit promoter. Endocrinology. 2002;143:1018-1025.
    • (2002) Endocrinology , vol.143 , pp. 1018-1025
    • Harris, D.1    Bonfil, D.2    Chuderland, D.3
  • 51
    • 0031685160 scopus 로고    scopus 로고
    • Mitotic phosphoepitopes precede paired helical filaments in Alzheimer's disease
    • Vincent I, Zheng JH, Dickson DW, et al. Mitotic phosphoepitopes precede paired helical filaments in Alzheimer's disease. Neurobiol Aging. 1998;19:287-296.
    • (1998) Neurobiol Aging , vol.19 , pp. 287-296
    • Vincent, I.1    Zheng, J.H.2    Dickson, D.W.3
  • 52
    • 0034114486 scopus 로고    scopus 로고
    • An association of elevated serum gonadotropin concentrations and Alzheimer disease?
    • Bowen RL, Isley JP, Atkinson RL. An association of elevated serum gonadotropin concentrations and Alzheimer disease? J Neuroendocrinol. 2000;12:351-354.
    • (2000) J Neuroendocrinol , vol.12 , pp. 351-354
    • Bowen, R.L.1    Isley, J.P.2    Atkinson, R.L.3
  • 53
    • 0034846382 scopus 로고    scopus 로고
    • Elevated gonadotropin levels in patients with Alzheimer disease
    • Short RA, Bowen RL, O'Brien PC, et al. Elevated gonadotropin levels in patients with Alzheimer disease. Mayo Clin Proc. 2001;76:906-909.
    • (2001) Mayo Clin Proc , vol.76 , pp. 906-909
    • Short, R.A.1    Bowen, R.L.2    O'Brien, P.C.3
  • 54
    • 0028959562 scopus 로고
    • Peripheral and intracerebroventricular administration of human chorionic gonadotropin alters several hippocampus-associated behaviors in cycling female rats
    • Lukacs H, Hiatt ES, Lei ZM, et al. Peripheral and intracerebroventricular administration of human chorionic gonadotropin alters several hippocampus-associated behaviors in cycling female rats. Horm Behav. 1995;29:42-58.
    • (1995) Horm Behav , vol.29 , pp. 42-58
    • Lukacs, H.1    Hiatt, E.S.2    Lei, Z.M.3
  • 55
    • 0041419869 scopus 로고    scopus 로고
    • Increased p27, an essential component of cell cycle control, in Alzheimer's disease
    • Ogawa O, Lee HG, Zhu X, et al. Increased p27, an essential component of cell cycle control, in Alzheimer's disease. Aging Cell. 2003;2:105-110.
    • (2003) Aging Cell , vol.2 , pp. 105-110
    • Ogawa, O.1    Lee, H.G.2    Zhu, X.3
  • 56
    • 0034923434 scopus 로고    scopus 로고
    • Oxidative damage is the earliest event in Alzheimer disease
    • Nunomura A, Perry G, Aliev G, et al. Oxidative damage is the earliest event in Alzheimer disease. J Neuropathol Exp Neurol. 2001;60:759-767.
    • (2001) J Neuropathol Exp Neurol , vol.60 , pp. 759-767
    • Nunomura, A.1    Perry, G.2    Aliev, G.3
  • 57
    • 0034686614 scopus 로고    scopus 로고
    • Estrogen as a treatment for alzheimer disease
    • Mulnard RA. Estrogen as a treatment for alzheimer disease. JAMA. 2000;284:307-308.
    • (2000) JAMA , vol.284 , pp. 307-308
    • Mulnard, R.A.1
  • 58
    • 0034704547 scopus 로고    scopus 로고
    • Estrogen replacement therapy for treatment of mild to moderate Alzheimer disease: A randomized controlled trial. Alzheimer's Disease Cooperative Study
    • Mulnard RA, Cotman CW, Kawas C, et al. Estrogen replacement therapy for treatment of mild to moderate Alzheimer disease: a randomized controlled trial. Alzheimer's Disease Cooperative Study. JAMA. 2000;283:1007-1015.
    • (2000) JAMA , vol.283 , pp. 1007-1015
    • Mulnard, R.A.1    Cotman, C.W.2    Kawas, C.3
  • 59
    • 0027285453 scopus 로고
    • Neuropsychologic dysfunction in women following leuprolide acetate induction of hypoestrogenism
    • Varney NR, Syrop C, Kubu CS, et al. Neuropsychologic dysfunction in women following leuprolide acetate induction of hypoestrogenism. J Assist Reprod Genet. 1993;10:53-57.
    • (1993) J Assist Reprod Genet , vol.10 , pp. 53-57
    • Varney, N.R.1    Syrop, C.2    Kubu, C.S.3
  • 60
    • 0029900525 scopus 로고    scopus 로고
    • "Add-back" estrogen reverses cognitive deficits induced by a gonadotropin-releasing hormone agonist in women with leiomyomata uteri
    • Sherwin BB, Tulandi T. "Add-back" estrogen reverses cognitive deficits induced by a gonadotropin-releasing hormone agonist in women with leiomyomata uteri. J Clin Endocrinol Metab. 1996;81:2545-2549.
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 2545-2549
    • Sherwin, B.B.1    Tulandi, T.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.