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Journal of Physiology and Pharmacology

Volumn 51, Issue 4, 2000, Pages 655-672

Selective inhibition of arachidonic acid epoxidation in vivo

(3) Brand Schieber, E a Falck, J F b Schwartzman, M a

a NEW YORK MEDICAL COLLEGE (United States)

b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER (United States)

Author keywords

Cytochrome P450; Epoxyeicosanoids; N methylsulphonyl 6 (2 propargyloxyphenyl) hexanamide (MS PPOH); Renal function

Indexed keywords

2 HYDROXYPROPYL BETA CYCLODEXTRIN; ARACHIDONIC ACID; CYTOCHROME P450; CYTOCHROME P450 INHIBITOR; EPOXYICOSATRIENOIC ACID; N METHYLSULFONYL 6 (2 PROPARGYLOXYPHENYL)HEXANAMIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARACHIDONIC ACID METABOLISM; BLOOD VESSEL TONE; CONFERENCE PAPER; CONTROLLED STUDY; DRUG INHIBITION; EPOXIDATION; IN VIVO STUDY; KIDNEY FUNCTION; MALE; NONHUMAN; POTASSIUM EXCRETION; RAT; SODIUM EXCRETION; URINARY EXCRETION; URINE FLOW RATE;

8,11,14-EICOSATRIENOIC ACID; AMIDES; ANIMALS; ARACHIDONIC ACID; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYCLODEXTRINS; CYTOCHROME P-450 ENZYME SYSTEM; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; FATTY ACIDS, UNSATURATED; HUMANS; IMMUNOBLOTTING; KIDNEY; MALE; MICONAZOLE; MICROSOMES; ORGANOPHOSPHORUS COMPOUNDS; RATS; RATS, SPRAGUE-DAWLEY; RECOMBINANT PROTEINS; SULFONES;

EID: 0034519059 PISSN: 08675910 EISSN: None Source Type: Journal
DOI: None Document Type: Conference Paper

Times cited : (39)

References (51)

1
- 0020026257
- Effects of 2,3,7,8-tetchlorodibenzop-dioxin and phenobarbital on the occurrence and distribution of four cytochrone P450 isozymes in rabbit kidney, lung and liver
- (1982) Can Res , vol.42 , pp. 1423-1432
- Dees, J.H.¹ Masters, B.B.S.² Müller-Eberhard, V.³ Johnson, E.F.⁴

2
- 0026356150
- CYP 4A subfamily: Functional analysis by immunocytochemistry and in situ hybridization
- (1991) Methods in Enzymol , vol.206 , pp. 273-283
- Hardwick, J.P.¹

3
- 0027329156
- 20-hydroxyeicosatetraenoic acid is an endogenous vasoconstrictor of canine renal arcuate arteries
- (1993) Circ Res , vol.72 , pp. 126-136
- Ma, Y.-H.¹ Gebremedhin, D.² Schwartzman, M.L.³ Falck, J.R.⁴ Clark, J.E.⁵ Masters, B.S.S.⁶ Harder, D.R.⁷ Roman, R.J.⁸

4
- 0000117512
- Arachidonic acid ω/ω-1 hydroxylase along the nephron of the spontaneously hypertensive rat
- (1992) Am J Physiol , vol.262
- Omata, K.¹ Abraham, N.G.² Laniado-Schwartzman, M.³

5
- 0024350111
- The rat clofibrate-inducibleCYP4A gene subfamily I. Complete intron and exon sequence of the CYP4A1 and CYP4A2 genes, unique exon organization, and identification of a conserved 19-bp upstream element
- (1989) DNA , vol.8 , pp. 503-516
- Kimura, S.¹ Hanioka, N.² Matsunaga, E.³ Gonzales, F.J.⁴

6
- 0024385160
- The rat clofibrate-inducible CYP4A gene subfamily. II. cDNA sequence of IVA3, mapping of the CYP4A locus to mouse chromosome 4, and coordinate and tissue-specific regulation of the CYP4A genes
- (1989) DNA , vol.8 , pp. 517-525
- Kimura, S.¹ Hardwick, J.P.² Kozak, C.A.³ Gonzales, F.J.⁴

7
- 0032997280
- Kinetic profile of the rat CYP4A isoforms: Arachidonic acid metabolism and isoform-specific inhibitors
- (1999) Am J Physiol , vol.276
- Nguyen, X.¹ Wang, M.H.² Reddy, K.M.³ Falck, J.R.⁴ Schwartzman, M.L.⁵

8
- 0025027879
- Cloning and characterization of a novel member of the cytochrome P450 subfamily IVA in rat prostate
- (1990) DNA , vol.9 , pp. 567-577
- Stromstedt, M.¹ Hayashi, S.I.² Zaphiropoulos, P.G.³ Gustafsson, J.A.⁴

9
- 0027164207
- Formation of 19(S)-, 19(R)-, and 18(R)-hydroxyeicosatetraenoic acids by alcohol-inducible cytochrome 2E1
- (1993) J Biol Chem , vol.268 , pp. 12912-12918
- Laethem, R.M.¹ Balazy, M.² Falck, J.R.³ Laethem, C.L.⁴ Koop, D.R.⁵

10
- 0028283819
- Epoxidation of arachidonic acid as an active-site probe of cytochrome p-450 2B isoforms
- (1994) Biochim Biophys Acta , vol.1206 , pp. 42-48
- Laethem, R.M.¹ Halpert, J.R.² Koop, D.R.³

11
- 0027056410
- Identification of rabbit cytochrome P450 2C1 and 2C2 as arachidonic acid epoxygenase
- (1992) Mol Pharmacol , vol.42 , pp. 958-963
- Laethem, R.M.¹ Koop, D.R.²

12
- 0029039791
- Arachidonic acid metabolism by human cytochrome P450s 2C8, 2C9, 2E1 and 1A2: Regioselective oxygenation and evidence for a role for CYP2C enzymes in arachidonic acid epoxygenation in human liver microsomes
- (1995) Arch Biochem Biophys , vol.320 , pp. 380-389
- Rifkind, A.B.¹ Lee, C.² Chang, T.K.H.³ Waxman, D.J.⁴

13
- 0033009103
- P450 subfamily CYP2J and their role in the bioactivation of arachidonic acid in extrahepatic tissues
- (1999) Drug Metab Rev , vol.31 , pp. 205-234
- Scarborough, P.E.¹ Ma, J.² Qu, W.³ Zeldin, D.C.⁴

14
- 0030589540
- Cloning, sequencing and cDNA-directed expression of the rat renal CYP4A2: Arachidonic acid ω-hydroxylation and 11,12-epoxidation by CYP4A2 protein
- (1996) Arch Biochem Biophys , vol.336 , pp. 240-250
- Wang, M.-H.¹ Stec, D.E.² Balazy, M.³ Mastyugin, V.⁴ Yang, C.S.⁵ Roman, R.J.⁶ Laniado Schwartzman, M.⁷

15
- 0030028233
- Formation and actions of 20-hydroxyeicosatetraenoic acid in rat renal arterioles
- (1996) Am J Physiol , vol.270
- Imig, J.D.¹ Zou, A.-P.² Stec, D.E.³ Harder, D.R.⁴ Falck, J.R.⁵ Roman, R.J.⁶

16
- 0030029461
- + channel in renal arterioles
- (1996) Am J Physiol , vol.270
- Zou, A.-P.¹ Fleming, J.T.² Falck, J.R.³ Jacobs, E.R.⁴ Gebremedhin, D.⁵ Harder, D.R.⁶ Roman, R.J.⁷

17
- 0028271810
- Cytochrome P450 arachidonate metabolites affect ion fluxes in rabbit medullary thick ascending limb
- (1994) Am J Physiol , vol.266
- Escalante, B.¹ Erlij, D.² Falck, J.R.³ McGiff, J.C.⁴

18
- 0028807418
- + channel in the thick ascending limb of the rat kidney
- (1995) J Gen Physiol , vol.106 , pp. 727-743
- Wang, W.¹ Lu, M.²

19
- 0027471234
- Role of cytochrome P450 in elevating renal vascular tone in spontaneously hypertensive rats
- (1993) J Vasc Res , vol.30 , pp. 53-60
- Gebremedhin, D.¹ Ma, Y.-H.² Umig, J.D.³ Harder, D.R.⁴ Roman, R.J.⁵

20
- 0032784521
- Contribution of cytochrome P450 epoxygenase and hydroxylase pathways to afferent arteriolar autoregulatory responsiveness
- (1999) Br J Pharmacol , vol.127 , pp. 1399-1405
- Imig, J.D.¹ Falck, J.R.² Inscho, E.W.³

21
- 0025967421
- Inhibitors of cytochrome P450 attenuate the myogenic response of dog renal arcuate arteries
- (1991) Circ Res , vol.68 , pp. 1154-1163
- Kauser, K.¹ Clark, J.E.² Masters, B.S.³ Ortiz de Montellano, P.R.⁴ Ma, Y.-H.⁵ Harder, D.R.⁶ Roman, R.J.⁷

22
- 0029976078
- Role of 20-HETE in elevating loop chloride reabsorption in Dahl SS/Jr rats
- (1996) Hyperten , vol.27 , pp. 631-635
- Zou, A.-P.¹ Drummond, H.A.² Roman, R.J.³

23
- 0028296987
- Inhibition of renal vascular 20-HETE production impairs autoregulation of renal blood flow
- (1994) Am J Physiol , vol.266
- Zou, A.-P.¹ Imig, J.D.² Kaldunski, M.³ Ortiz de Montellano, P.R.⁴ Sui, Z.⁵ Roman, R.J.⁶

24
- 0028284028
- Effect of 450 ω-hydroxylase metabolites of arachidonic acid on tubuloglomerular feedback
- (1994) Am J Physiol Renal Fluid Electrolyte Physiol , vol.266
- Zou, A.-P.¹ Imig, J.D.² Ortiz de Montaellano, P.R.³ Sui, Z.⁴ Falck, J.R.⁵ Roman, R.J.⁶

25
- 0026567720
- Cyclooxygenase dependency of the recovascular actions of cytochrome P450-derived arachidonate metabolites
- (1992) J Pharmacol Exp Ther , vol.260 , pp. 104-109
- Carroll, M.A.¹ Pilar Gracia, M.² Falck, J.R.³ Mc Giff, J.C.⁴

26
- 0025990867
- Glomerular stereospecific synthesis and hemodynamic actions of 8,9-epoxyeicosatrienoic acid in rat kidney
- (1991) Am J Physiol , vol.261
- Katoh, T.¹ Takahashi, K.² Capdevila, J.³ Karara, A.⁴ Falck, J.R.⁵ Jacobson, H.R.⁶ Badr, K.F.⁷

27
- 0029888211
- - channel activity
- (1996) Am J Physiol , vol.270
- Zou, A.-P.¹ Fleming, J.T.² Falck, J.R.³ Jacobs, E.R.⁴ Gebremedhin, D.⁵ Harder, D.R.⁶ Roman, R.J.⁷

28
- 0025183659
- + exchange and are mitogenic in cultured rat glomerular mesangial cells
- (1990) Cell Physiol , vol.144 , pp. 429-437
- Harris, R.C.¹ Homma, T.² Jacobson, H.R.³ Capdevila, J.H.⁴

29
- 0024804372
- Cytochrome P450 metabolites of arachidonic acid are potent inhibitors of vasopressin action on rabbit cortical collecting duct
- (1989) J Clin Invest , vol.84 , pp. 1805-1812
- Hirt, H.¹ Capdevila, J.² Falck, J.R.³ Breyer, M.D.⁴ Jacobson, H.R.⁵

30
- 0029059860
- 5,6-EET inhibits ion transport in collecting ducts by stimulating endogenous prostaglandin synthesis
- (1995) Am J Physiol , vol.268
- Sakairi, Y.¹ Jacobson, H.R.² Noland, T.D.³ Capdevila, J.H.⁴ Falck, J.R.⁵ Breyer, M.D.⁶

31
- 0025214061
- Cytochrome P450 arachidonate metabolites in rat kidney: Characterization and hemodynamic responses
- (1990) Am J Physiol , vol.258
- Takahashi, K.J.¹ Capdevila, A.² Karara, J.R.³ Falck, J.R.⁴ Jacobson, H.R.⁵ Badr, K.F.⁶

32
- 0006591141
- Increased dietary salt attenuates a renal vasoconstrictor mechanism-mediated by 20-HETE
- (1996) Hyperten , vol.28 , pp. 539
- Brand-Schieber, E.¹ Takizawa, H.² Falck, J.R.³ Laniado Schwartzman, M.⁴ Nasjletti, A.⁵

33
- 0026808882
- Cytochrome P450 arachidonic acid epoxygenase: Regulatory control of the renal epoxygenase by dietary salt loading
- (1992) J Biol Chem , vol.267 , pp. 21720-21726
- Capdevila, J.H.¹ Shouzou, W.² Yan, J.³ Karara, A.⁴ Jacobson, H.R.⁵ Falck, J.R.⁶ Guengerich, F.P.⁷ DuBois, R.N.⁸

34
- 0027301319
- Elevated renovascular tone in young spontaneously hypertensive rats: Role of cytochrome P450
- (1993) Hyperten , vol.22 , pp. 357-364
- Imig, J.D.¹ Falck, J.R.² Gebremedhin, D.³ Harder, D.R.⁴ Roman, R.J.⁵

35
- 0027996820
- Experimental and/or geneticaly controlled alterations of the renal microsomal cytochrome P450 epoxygenase induced hypertension in rats fed a high salt diet
- (1994) J Clin Invest , vol.94 , pp. 2414-2420
- Makita, K.¹ Takahashi, K.² Karara, A.³ Jacobson, H.R.⁴ Falck, J.R.⁵ Capdevila, J.H.⁶

36
- 0024587145
- Treatment with tin prevents the development of hypertension in spontaneously hypertensive rats
- (1989) Science , vol.243 , pp. 388-390
- Sacerdoti, D.¹ Escalante, B.² Abraham, N.G.³ McGiff, J.C.⁴ Levere, R.D.⁵ Schwartzman, M.L.⁶

37
- 0028087299
- Effect of 17-octadecynoic acid, a suicide-substrate inhibitor of cytochrome P450 fatty acid ω-hydroxylase, on renal function
- (1994) J Pharmacol Exp Ther , vol.268 , pp. 474-481
- Zou, A.-P.¹ Ma, Y.-H.² Sui, Z.-H.³ Ortiz de Montellano, P.R.⁴ Clark, J.E.⁵ Masters, B.S.⁶ Roman, R.J.⁷

38
- 0024236331
- The molecular biology of cytochrome P450
- (1988) Pharmacol Rev , vol.40 , pp. 275-288
- Gonzalez, F.J.¹

39
- 0021345344
- Specific inactivation of hepatic fatty acid hydroxylases by acetylenic fatty acids
- (1984) J Biol Chem , vol.259 , pp. 4136-4141
- Ortiz de Montellano, P.R.¹ Reich, N.O.²

40
- 0024501044
- Prostaglandin and fatty acid ω- and (ω-1)-oxidation in rabbit lung. Acetylenic fatty acid mechanism-based inactivators as specific inhibitors
- (1989) J Biol Chem , vol.264 , pp. 749-756
- Muerhoff, A.S.¹ Williams, D.E.² Reich, N.O.³ CaJacob, C.A.⁴ Ortiz de Montellano, P.R.⁵ Masters, B.S.S.⁶

41
- 0031887331
- Cytochrome P450-derived arachidonic acid metabolism in the rat kidney: Characterization of selective inhibitors
- (1998) J Pharmacol Exp Ther , vol.284 , pp. 966-973
- Wang, M.-H.¹ Brand-Schieber, E.² Zand, B.A.³ Nguyen, X.⁴ Falck, J.R.⁵ Balu, N.⁶ Laniado Schwartzman, M.⁷

42
- 0030708712
- Eicosanoid biosynthesis: Differential inhibition of cytochrome P450 epoxygenase and ω-hydroxylase
- (1997) Bioorg Medicinal Chem Lett , vol.7 , pp. 3053-3056
- Falck, J.R.¹ Belosludtsev, Y.² Kishta Reddy, K.³ Malla Reddy, K.⁴ Fiona Shortt, M.⁵ Chauhan, K.⁶ Capdevila, J.H.⁷ Wei, S.⁸

43
- 0029122098
- Molecular cloning, expression and characterization of an endogenous human cytochrome P450 arachidonic acid epoxygenase isoform
- (1995) Arch Biochem Biophys , vol.322 , pp. 76-86
- Zeldin, D.C.¹ DuBois, R.N.² Falck, J.R.³ Capdevila, J.H.⁴

44
- 0023866354
- Inhibitors of cytochrome P450 dependent arachidonic acid metabolism
- (1988) Arch Biochem Biophys , vol.261 , pp. 257-263
- Capdevila, J.¹ Gil, L.² Orellana, M.³ Marnett, L.J.⁴ Mason, J.I.⁵ Yadagiri, P.⁶ Falck, J.R.⁷

45
- 0029029763
- Preliminary safety evaluation of parenterally administered sulfoalkyl ether beta-cyclodextrin derivatives
- published erratum appears in J Pharm Sci 1995; Dec; 84(12): 1492
- (1995) J Phar Sci , vol.84 , pp. 927-932
- Rajewski, R.A.¹ Traiger, G.² Bresnahan, J.³ Jaberaboansari, P.⁴ Stella, V.J.⁵ Thompson, D.O.⁶

46
- 0025967184
- The utility of 2-hydroxypropyl-beta-cyclodextrin as a vehicle for the intracerebral and intrathecal administration of drugs
- Life Sci , vol.48 , pp. 623-633
- Yaksh, T.L.¹ Jang, J.D.² Nishiuchi, Y.³ Braun, K.P.⁴ Ro, S.G.⁵ Goodman, M.⁶

47
- 0026072030
- Modulation of rat hepatic microsomal monoxygenase enzymes and cytotoxicity by diallyl sulfide
- (1991) Toxicol Appl Pharmacol , vol.108 , pp. 342-354
- Brady, J.F.¹ Wang, M.-H.² Hong, J.-Y.³ Xiao, F.⁴ Li, Y.⁵ Yoo, J.-S.H.⁶ Ming, S.M.⁷ Lee, M.-J.⁸ Fukuto, J.M.⁹ Gapac, J.¹⁰ Yang, C.S.¹¹

48
- 0019422068
- Destruction of cytochrome P-450 by allylisopropylacetamide is a suicidal process
- (1981) Arch Biochem Biophys , vol.206 , pp. 43-50
- Ortiz de Montellano, P.R.¹ Mico, B.A.²

49
- 0031844011
- Inhibition of renal arachidonic acid omega-hydroxylase activity with ABTreduces blood pressure in the SHR
- (1998) Am J Physiol , vol.275
- Su, P.¹ Kaushal, K.M.² Kroetz, D.L.³

50
- 0027493771
- Molecular cloning, expression and enzymatic characterization of the rat kidney cytochrome P-450 arachidonic acid epoxygenase
- (1993) J Biol Chem , vol.268 , pp. 13565-13570
- Karara, A.¹ Makita, K.² Jacobson, H.R.³ Falck, J.R.⁴ Guengerich, F.P.⁵ DuBois, R.N.⁶ Capdevila, J.H.⁷

51
- 0032611973
- Epoxyeicosatrienoic acids. Biosynthesis, regulation and actions
- (1999) Methods Mol Biol , vol.120 , pp. 173-192
- Imig, J.D.¹

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