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Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 16, 2005, Pages 3691-3695

Discovery and SAR of 4-amino-2-biarylbutylurea MCH 1 receptor antagonists through solid-phase parallel synthesis

(6) Guo, Tao a Hunter, Rachael C a Gu, Huizhong a Rokosz, Laura L a Stauffer, Tara M a Hobbs, Doug W a

a PHARMACOPEIA INC (United States)

Author keywords

MCH; MCH1R antagonists; Obesity; Solid phase parallel synthesis

Indexed keywords

IODINE 125; MELANIN CONCENTRATING HORMONE; RECEPTOR BLOCKING AGENT; UREA DERIVATIVE;

ARTICLE; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SCREENING; SCINTILLATION; SOLID PHASE SYNTHESIS; STRUCTURE ACTIVITY RELATION;

COMBINATORIAL CHEMISTRY TECHNIQUES; DRUG EVALUATION, PRECLINICAL; HUMANS; MOLECULAR STRUCTURE; RECEPTORS, SOMATOSTATIN; STRUCTURE-ACTIVITY RELATIONSHIP; UREA;

EID: 22844447196 PISSN: 0960894X EISSN: None Source Type: Journal
DOI: 10.1016/j.bmcl.2005.05.039 Document Type: Article

Times cited : (19)

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