Requirement of retinoic acid receptor isotypes α, β, and γ during the initial steps of neural differentiation of PCC7 cells

Molecular Endocrinology

Volumn 19, Issue 6, 2005, Pages 1629-1645

  Zechel, Christina ^a  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CELL NUCLEUS RECEPTOR; OCTAMER TRANSCRIPTION FACTOR 4; RETINOIC ACID RECEPTOR ALPHA; RETINOIC ACID RECEPTOR BETA; RETINOIC ACID RECEPTOR GAMMA; RETINOID X RECEPTOR;

ANIMAL CELL; ARTICLE; CANCER CELL CULTURE; CELL LINE; CELL PROLIFERATION; DISSOCIATION; DOWN REGULATION; MOUSE; NERVE CELL DIFFERENTIATION; NONHUMAN; PRIORITY JOURNAL; UPREGULATION;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CELL DEATH; CELL DIFFERENTIATION; CELL LINE; CELL LINE, TUMOR; CELL PROLIFERATION; DNA, COMPLEMENTARY; DNA-BINDING PROTEINS; DOWN-REGULATION; GENES, REPORTER; GLUTATHIONE TRANSFERASE; HUMANS; IMMUNOHISTOCHEMISTRY; KINETICS; LIGANDS; MICE; NEURONS; OCTAMER TRANSCRIPTION FACTOR-3; PLASMIDS; PROTEIN BINDING; PROTEIN ISOFORMS; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, RETINOIC ACID; RECOMBINANT FUSION PROTEINS; RETINOID X RECEPTORS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; SIGNAL TRANSDUCTION; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTORS; TRANSFECTION; TRETINOIN; UP-REGULATION;

MURINAE;

EID: 22344450991     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/me.2004-0540     Document Type: Article

References (61)

1. Zile MH 2001 Function of vitamin A in vertebrate embryonic development. J Nutr 131:705-708
2. Panchision DM, McKay DG 2002 The control of neural stem cells by morphogenic signals. Curr Opin Genet Dev 12:478-487
3. Malaspina A, Pearce RK, Graeber MB 2003 Nuclear hormone and orphan receptors: their role in neuronal differentiation and cytoprotection and in the pathogenesis of Parkinson's disease. Dev Neurosci 25:375-383
4. Gavalas A, Krumlauf R 2000 Retinoid signaling and hindbrain patterning. Curr Opin Genet Dev 10:380-386
5. Maden M 1998 Vertebrate development: a nervous vitamin. Curr Biol 8:R846-R849
6. Samad TA, Krezel W, Chambon P, Borrelli E 1997 Regulation of dopaminergic pathways by retinoids: activation of the D2 receptor promoter by members of the retinoic acid receptor-retinoid X receptor family. Proc Natl Acad Sci USA 94:14349-14354
7. Misner DL, Jacobs S, Shimizu Y, de Urquiza AM, Solomin L, Perlmann T, De Luca LM, Stevens CF, Evans RM 2001 Vitamin A deprivation results in reversible loss of hippocampal long term synaptic plasticity. Proc Natl Acad Sci USA 98:11714-11719
8. Gronemeyer H, Laudet V 1995 Transcription factors 3: nuclear receptors. Protein Profile 2:1173-1308
9. Allenby G, Bocquel MT, Saunders M, Kazmer S, Speck J, Rosenberger M, Lovey A, Kastner P, Grippo JF, Chambon P, Levin AA 1993 Retinoic acid receptors and retinoid X receptors: interactions with endogenous retinoic acids. Proc Natl Acad Sci USA 90:30-34
10. Egea PF, Klaholz BP, Moras D 2000 Ligand-protein interactions in nuclear receptors of hormones. FEBS Lett 476:62-67
11. Giguère V 1994 Retinoic acid receptors and cellular retinoid binding proteins: complex interplay in retinoid signaling. Endocr Rev 15:61-79
12. Chambon P 1996 A decade of molecular biology of retinoic acid receptors. FASEB J 10:940-954
13. Kastner P, Mark M, Ghyselinck N, Krezel W, Dupe V, Grondona JM, Chambon P 1997 Genetic evidence that the retinoid signal is transduced by heterodimeric RXR/ RAR functional units during mouse development. Development 124:313-326
14. Privalsky ML 2004 The role of corepressors in transcriptional regulation by nuclear hormone receptors. Annu Rev Physiol 66:315-360
15. Xu HE, Stanley TB, Montana VG, Lambert MH, Shearer BG, Cobb JE, McKee DD, Galardi CM, Plunket KD, Nolte RT, Parks DJ, Moore JT, Kliewer SA, Willson TM, Stimmel JB 2002 Structural basis for antagonist-mediated recruitment of nuclear co-repressors by PPARα. Nature 415:813-817
16. Perissi V, Aggarwal A, Glass CK, Rose DW, Rosenfeld MG 2004 A corepressor/coactivator exchange complex required for transcriptional activation by nuclear receptors and other regulated transcription factors. Cell 20: 511-526
17. Smith CL, O'Malley BW 2004 Coregulator function: a key to understanding tissue specificity of selective receptor modulators. Endocr Rev 25:45-71
18. Bourguet W, Germain P, Gronemeyer H 2000 Nuclear receptor ligand-binding domains: three-dimensional structures, molecular interactions and pharmacological implications. Trends Pharmacol Sci 21:381-388
19. Mark M, Ghyselinck NB, Kastner P, Dupe V, Wendling O, Krezel W, Mascrez B, Chambon P 1998 Mesectoderm is a major target of retinoic acid action. Eur J Oral Sci 106:24-31
20. Dupé V, Ghyselinck NB, Wendling O, Chambon P, Mark M 1999 Key roles of retinoic acid receptors α and β in the patterning of the caudal hindbrain, pharyngeal arches and otocyst in the mouse. Development 126:5051-5059
21. Wendling O, Ghyselinck NB, Chambon P, Mark M 2001 Roles of retinoic acid receptors in early embryonic morphogenesis and hindbrain patterning. Development 128: 2031-2038
22. Krezel W, Ghyselinck N, Samad TA, Dupé V, Kastner P, Borrelli E, Chambon P 1998 Impaired locomotion and dopamine signaling in retinoid receptor mutant mice. Science 279:863-867
23. Chiang MY, Misner D, Kempermann G, Schikorski T, Giguère V, Sucov HM, Gage FH, Stevens CF, Evans RM 1998 An essential role for retinoid receptors RARβ and RXRγ in long-term potentiation and depression. Neuron 21:1353-1361
24. Boylan JF, Lufkin T, Achkar CC, Taneja R, Chambon P, Gudas LJ 1995 Targeted disruption of retinoic acid receptor α (RARα) and RARγ results in receptor-specific alterations in retinoic acid-mediated differentiation and retinoic acid metabolism. Mol Cell Biol 15:843-851
25. Roy B, Taneja R, Chambon P 1995 Synergistic activation of retinoic acid (RA)-responsive genes and induction of embryonal carcinoma cell differentiation by an atRA receptor α (RARα)-, RARβ-, or RARγ-selective ligand in combination with a retinoid X receptor-specific ligand. Mol Cell Biol 15:6481-6487
26. Clifford J, Chiba H, Sobieszczuk D, Metzger D, Chambon P 1996 RXRα-null F9 embryonal carcinoma cells are resistant to the differentiation, anti-proliferative and apoptotic effects of retinoids. EMBO J 15:4142-4155
27. Taneja R, Roy B, Plassat JL, Zusi CF, Ostrowski J, Reczek PR, Chambon P 1996 Cell-type and promoter-context dependent retinoic acid receptor (RAR) redundancies for RARβ2 and Hoxa-1 activation in F9 and P19 cells can be artifactually generated by gene knockouts. Proc Natl Acad Sci USA 93:6197-6202
28. Wallé n-Mackenzie A, Mata de Urquiza A, Petersson S, Rodriguez FJ, Friling S, Wagner J, Ordentlich P, Lengqvist J, Heyman RA, Arenas E, Perlmann T 2003 Nurr1-RXR heterodimers mediate RXR ligand-induced signaling in neuronal cells. Genes Dev 17:3036-3047
29. Pfeiffer SE, Jakob H, Mikoshiba K, Dubois P, Guenet JL, Nicolas JF, Gaillard J, Chevance G, Jacob F 1981 Differentiation of a teratocarcinoma line: preferential development of cholinergic neurons. J Cell Biol 88:57-66
30. Berger C, Reinhardt S, Rentrop M, Bachmann M, Weiser T, Link E, Wienrich M, Jahn R, Maelicke A 1997 De novo acquisition of neuronal polarity in retinoic acid-induced embryonal carcinoma cells. Eur J Cell Biol 74:224-230
31. Esdar C, Milasta S, Maelicke A, Herget T 2001 Differentiation-associated apoptosis of neural stem cells is effected by Bcl-2 overexpression: impact on cell lineage determination. Eur J Cell Biol 80:539-553
32. Müller-Husmann G, Reinhardt S, Strähle M, Lang E, Maelicke A 1994 Ex-1, a surface antigen of mouse neuronal progenitor cells and mature neurons. Dev Brain Res 83:262-277
33. Ghyselinck NB, Dupe V, Dierich A, Messaddeq N, Garnier JM, Rochette-Egly C, Chambon P, Mark M 1997 Role of the retinoic acid receptor β (RARβ) during mouse development. Int J Dev Biol 41:425-447
34. Egea PF, Mitschler A, Moras D 2002 Molecular recognition of agonist ligands by RXRs. Mol Endocrinol 16: 987-997
35. Xu J, Li Q 2003 Review of the in vivo functions of the p160 steroid receptor coactivator family. Mol Endocrinol 17:1681-1692
36. Benko S, Love JD, Beladi M. Schwabe JW, Nagy L 2003 Molecular determinants of the balance between corepressor and co-activator recruitment to the retinoic acid receptor. J Biol Chem 278:43797-43806
37. Kao HY, Han CC, Komar AA, Evans RM 2003 Corepressor release but not ligand binding is a prerequisite for transcription activation by human retinoid receptor α ligand binding domain. J Biol Chem 278:7366-7373
38. Sohn YC, Kim SW, Lee S, Kong YY, Na DS, Lee SK, Lee JW 2003 Dynamic inhibition of nuclear receptor activation by co-repressor binding. Mol Endocrinol 17:366-372
39. Germain P, Iyer J, Zechel C, Gronemeyer H 2002 Coregulator recruitment and the mechanism of retinoic acid receptor synergy. Nature 415:187-192
40. Zechel C 2002 Synthetic retinoids dissociate coactivator binding from corepressor release. J Recept Signal Transduct Res 22:31-61
41. Hauksdottir H, Farboud B, Privalsky ML 2003 Retinoic acid receptors β and γ do not repress, but instead activate target gene transcription in both the absence and presence of hormone ligand. Mol Endocrinol 17:373-385
42. Rochette-Egly C, Gaub MP, Lutz Y, Ali S, Scheuer I, Chambon P 1992 Retinoic acid receptor-β: immunodetection and phosphorylation on tyrosine residues. Mol Endocrinol 6:2197-1209
43. Etchamendy N, Enderlin V, Marighetto A, Pallet V, Higueret P, Jaffard R 2003 Vitamin A deficiency and relational memory deficit in adult mice: relationships with changes in brain retinoid signalling. Behav Brain Res 145:37-49
44. Sattler U, Samochocki M, Maelicke A, Zechel C 2004 The expression level of the orphan nuclear receptor GCNF is critical for neuronal differentiation. Mol Endocrinol 18: 2714-2726
45. Rochette-Egly C, Chambon P 2001 F9 embryocarcinoma cells: a cell autonomous model to study the functional selectivity of RARs and RXRs in retinoid signaling. Histol Histopathol 16:909-922
46. Chiba H, Clifford J, Metzger D, Chambon P 1997 Specific and redundant functions of retinoid X receptor/retinoic acid receptor heterodimers in differentiation, proliferation, and apoptosis of F9 embryonal carcinoma cells. J Cell Biol 139:735-747
47. Agarwal C, Chandraratna RAS, Johnson AT, Rorke EA, Eckert RL 1996 AGN193109 is a highly effective antagonist of retinoid action in human ectocervical epithelial cells. J Biol Chem 271:12209-12212
48. Etchamendy N, Enderlin V, Marighetto A, Vouimba RM, Pallet V, Jaffard R, Higueret P 2001 Alleviation of a selective age-related relational memory deficit in mice by pharmacologically induced normalization of brain retinoid signaling. J Neurosci 21:6423-6429
49. Farah MH, Olson JM, Sucic HB, Hume RI, Tapscott SJ, Turner DL 2000 Generation of neurons by transient expression of neural bHLH proteins in mammalian cells. Development 127:693-702
50. Torii M, Matsuzaki F, Osumi N, Kaibuchi K, Nakamura S, Casarosa S, Guillemot F, Nakafuku M 1999 Transcription factors Mash-1 and Prox-1 delineate early steps in differentiation of neural stem cells in the developing central nervous system. Development 126:443-456
51. Barreto G, Borgmeyer U, Dreyer C 2003 The germ cell nuclear factor is required for retinoic acid signaling during Xenopus development. Mech Dev 120:415-428
52. Cooney AJ, Lee CT, Lin SC, Tsai SY, Tsai MJ 2001 Physiological function of the orphans GCNF and COUPTF. Trends Endocrinol Metab 12:247-251
53. Pesce M, Schöler HR 2001 Oct4: a gatekeeper in the beginnings of mammalian development. Stem cells 19: 271-278
54. Fuhrmann G, Chung AC, Jackson KJ, Hummelke G, Baniahmad A, Sutter J, Sylvester I, Schöler HR, Cooney AJ 2001 Mouse germ line restriction of Oct4 expression by germ cell nuclear factor. Dev Cell 1:377-387
55. Dehmelt L, Halpain S 2004 Actin and microtubules in neurite initiation: are MAPs the missing link. J Neurobiol 58:18-33
56. Shen Y, Mani S, Meiri KF 2004 Failure to express GAP-43 leads to disruption of a multipotent precursor and inhibits astrocyte differentiation. Mol Cell Neurosci 26:390-405
57. Valtorta F, Pennuto M, Bonanomi D, Benfenati F 2004 Synaptophysin-leading actor or walk-on role in synaptic vesicle exocytosis? Bioessays 26:445-453
58. Boisvieux-Ulrich E, Le Pechon-Vallee C, Million K, Baeza-Squiban A, Houcine O, Guennou C, Reichert U, Marano F 2000 Differential effects of several retinoid receptor-selective ligands on squamous differentiation and apoptosis in airway epithelial cells. Cell Tissue Res 300:67-81
59. Szondy Z, Reichert U, Bernardon JM, Michel S, Toth R, Ancian P, Ajzner E, Fesus L 1997 Induction of apoptosis by retinoids and retinoic acid receptor gamma-selective compounds in mouse thymocytes through a novel apoptosis pathway. Mol Pharmacol 51:972-982
60. Szondy Z, Reichert U, Bernardon JM, Michel S, Toth R, Karaszi E, Fesus L 1998 Inhibition of activation-induced apoptosis of thymocytes by all-trans- and 9-cis-retinoic acid is mediated via retinoic acid receptor α. Biochem J 331:767-774
61. Sambrook J, Fritsch EF, Maniatis T 1989 Molecular cloning: a laboratory manual. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press