Key roles of retinoic acid receptors alpha and beta in the patterning of the caudal hindbrain, pharyngeal arches and otocyst in the mouse

Development

Volumn 126, Issue 22, 1999, Pages 5051-5059

  Dupé, Valérie ^a   Ghyselinck, Norbert B ^a   Wendling, Olivia ^a   Chambon, Pierre ^a   Mark, Manuel ^a  

^a INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

Author keywords

Cranial mesoderm; Endoderm; Hox genes; kreisler; Krox 20; Morphogen; Neural crest; Retinoic acid; Rhombencephalon

Indexed keywords

RETINOIC ACID; RETINOIC ACID RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN DEVELOPMENT; BRANCHIAL ARCH; CELL MIGRATION; CONTROLLED STUDY; CRANIAL NERVE; EMBRYO; EMBRYO PATTERN FORMATION; FEMALE; GENE EXPRESSION REGULATION; GENE MUTATION; INNER EAR; MALE; MOUSE; NEURAL CREST; NEUROECTODERM; NONHUMAN; PHARYNX; PRIORITY JOURNAL; RHOMBENCEPHALON;

ANIMALS; AVIAN PROTEINS; BRANCHIAL REGION; CELL COUNT; CELL MOVEMENT; CLEAVAGE STAGE, OVUM; CRANIAL NERVES; DNA-BINDING PROTEINS; EARLY GROWTH RESPONSE PROTEIN 2; EMBRYONIC AND FETAL DEVELOPMENT; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HOMEODOMAIN PROTEINS; MAFB TRANSCRIPTION FACTOR; MICE; NEURAL CREST; ONCOGENE PROTEINS; RECEPTORS, RETINOIC ACID; RHOMBENCEPHALON; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; TRETINOIN;

ANIMALIA; MAMMALIA;

EID: 0033430248     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (63)

1. Ang, H. L. and Duester, G. (1997). Initiation of relinoid signaling in primitive streak mouse embryos: Spatiotemporal expression patterns of receptors and metabolic enzymes for ligand synthesis. Dev. Dyn. 208, 536-543.
2. Bockman, D. E., Redmond, M. E. and Kirby, M. L. (1989). Alteration of early vascular development after ablation of cranial neural crest. Anat. Rec. 225, 209-217.
3. Chambon, P. (1996). A decade of molecular biology of retinoic acid receptors. FASEB. J. 10, 940-954.
4. Conlon, R. A. (1995). Retinoic acid and pattern formation in vertebrates. Trends. Genet. 11, 314-319.
5. Cordes, S. P. and Barsh, G. S. (1994). The mouse segmentation gene kr encodes a novel basic domain-leucine zipper transcription factor. Cell 79, 1025-1034.
6. Décimo, D., Georges-Labouesse, E. and Dollé, P. (1995). In situ hybridization to cellular RNA. In Gene Probe: A Practical Approach, vol.II, (ed. Hames, B. D. and Higgins, S. J.) New York: Oxford University Press.
7. Deutsch, U., Dressler, G. R. and Gruss, P. (1988). Pax-1, a member of a paired box homologous murine gene family, is expressed in segmented structures during development. Cell 53, 617-625.
8. Dollé, P., Ruberte, E., Leroy, P., Morriss-Kay, G. and Chambon, P. (1990). Retinoic acid receptors and cellular retinoid binding proteins. I. A systematic study of their differential pattern of transcription during mouse organogenesis. Development 110, 1133-1151.
9. Dupé, V., Davenne, M., Brocard, J., Dollé, P., Mark, M., Dierich, A., Chambon, P. and Rijli, F. M. (1997). In vivo functional analysis of the Hoxa-1 3′ retinoic acid response element (3′RARE). Development 124, 339-410.
10. Eichmann, A., Grapin-Botton, A., Kelly, L., Graf, T., Le Douarin, N. M. and Sieweke, M. (1997). The expression pattern of the mafB/kr gene in birds and mice reveals that the kreisler phenotype does not represent a null mutant. Mech. Dev. 65, 111-122.
11. Featherstone, M. S., Baron, A., Gaunt, S. J., Mattei, M. G. and Duboule, D. (1988). Hox-5.1 defines a homeo-box containing gene locus on mouse chromosome 2. Proc. Natl. Acad. Sci. USA 85, 4760-4764.
12. Frohman, M. A., Martin, G. R., Cordes, S., Halamek, L. P. and Barsh, G. S. (1993). Altered rhombomere-specific gene expression and hyoid bone differentiation in the mouse segmentation mutant kreisler (kr). Development 117, 925-936.
13. Gale, E., Prince, V., Lumsden, A., Clarke, J., Holder, N. and Maden, M. (1996). Late effects of retinoic acid on neural crest and aspects of rhombomere. Development 122, 783-793.
14. Gavalas, A., Studer, M., Lumsden, A., Rijli, F., Krumlauf, R. and Chambon, P. (1998). Hoxa-1 and Hoxb-1 synergize in patterning the hindbrain, cranial nerves and second pharyngeal arch. Development 125, 1123-1136.
15. Ghyselinck, N., Dupé, V., Dierich, A., Messaddeq, N., Garnier, J. M., Rochette-Egly, C., Chambon, P. and Mark M. (1997). Role of the retinoic acid receptor beta (RARβ) during mouse development. Int. J. Dev. Biol. 41, 425-447.
16. Godsave, S. F., Koster, C. H., Getahun, A., Mathu, M., Hooiveld, M., van der Wees, J., Hendriks, J. and Durston, A. J. (1998). Graded retinoid responses in the developing hindbrain. Dev. Dyn. 213, 39-49.
17. Gould, A., Itasaki, N. and Krumlauf, R. (1998). Initiation of rhombomeric Hoxb-4 expression requires induction by somites and a retinoic pathway. Neuron 21, 39-51.
18. Graham, A., Papalopulu, N., Lorimer, J., McVey, J. H., Tuddenham, E. G. D. and Krumlauf, R. (1988). Characterization of a murine homeo box gene, Hox-2.6, related to the Drosophila Deformed gene. Genes Dev. 2, 1424-1438.
19. Grapin-Botton, A., Bonnin, M. A. and Le Douarin N. M. (1997). Hox gene induction in the neural tube depends on three parameters: competence, signal supply and paralogue group. Development 124, 849-859.
20. Grapin-Botton, A., Bonnin, M. A., Sieweke, M. and Le Douarin N. M. (1998). Defined concentrations of a posteriorizing signal are critical for MafB/kreisler segmental expression in the hindbrain. Development 125, 1173-1181.
21. Guthrie, S. (1996). Patterning the hindbrain. Curr. Opin. Neurobiol. 6, 41-48.
22. Huang, D., Chen, S. W., Langsten, A. W. and Gudas, L. J. (1998). A conserved retinoic acid responsive element in !he murine Hoxb-1 gene is required for expression in the developing gut. Development 125, 3235-3246.
23. Hunt, P., Gulisano, M., Cook, M., Sham, M.-H., Faiella, A., Wilkinson, D., Boncinelli, E. and Krumlauf, R. (1991). A distinct Hox code for the branchial region of the vertebrate head. Nature 353, 861-864.
24. Itasaki, N., Sharpe, J., Morrison, A. and Krumlauf, R. (1996). Reprogramming Hox expression in the vertebrate hindbrain: influence of paraxial mesoderm and rhombomere transposition. Neuron 16, 487-500.
25. Kastner, P., Grondona, J. M., Mark, M., Gansmuller, A., LeMeur, M., Décimo, D., Vonesh, J. L., Dollé, P. and Chambon, P. (1994). Genetic analysis of RXRα developmental function: convergence of RXR and RAR signalling pathways in heart and eye morphogenesis. Cell. 78, 987-1003.
26. Kastner, P., Mark, M., and Chambon, P. (1995). Nonsteroid nuclear receptors: what are genetic studies telling us about their role in real life? Cell 83, 859-869.
27. Kastner, P., Mark, M., Ghyselinck, N., Krezel, W., Dupé, V., Grondona, J. M. and Chambon, P. (1997). Genetic evidence that the retinoid signal is transduced by heterodimeric RXR/RAR functional units during mouse development. Development 124, 313-326.
28. Kirby, M. L. and Waldo, K. L. (1990). Role of neural crest in congenital heart disease. Circulation. 82, 332-340.
29. Le Douarin, N. (1982). The Neural Crest. Cambridge University Press
30. Lohnes, D., Mark, M., Mendelsohn, C., Dollé, P., Dierich, A., Gorry, P., Gansmuller, A. and Chambon, P. (1994). Functions of the retinoic acid receptors (RARs) during development. I. Craniofacial and skeletal abnormalities in RAR double mutants. Development, 120, 2723-2748.
31. Lufkin, T., Lohnes, D., Mark, M., Dierich, A., Gorry, P., Gaub, M. P., LeMeur, M. and Chambon, P. (1993). High postnatal lethality and testis degeneration in retinoic acid receptor α mutant mice. Proc. Natl. Acad. Sci. 90, 7225-7229.
32. Luo, J., Sucov, H. M., Bader, J-A., Evans, R. M. and Giguère, V. (1996). Compound mutants for retinoic acid receptor (RAR)β and RARα1 reveal developmental functions for multiple RARβ isoforms. Mech. Dev. 55, 33-44.
33. Maden, M., Horton, C., Graham, A., Leonard, L., Pizzey, J., Siegenthaler, G., Lumsden, A. and Eriksson, U. (1992). Domains of cellular retinoic acid-binding protein I (CRABP 1) expression in the hindbrain and neural crest of the mouse embryo. Mech. Dev. 37, 13-23.
34. Maden, M., Gale, E., Kostetskii, I. and Zile, M. (1996). Vitamin A-deficient quail embryos have half a hindbrain and other neural defects. Curr. Biol. 6, 417-426.
35. Manzanares, M., Cordes, S., Ariza-McNaughton, L., Sadl, V., Maruthainar, K., Barsh, G. and Krumlauf, R. (1999a). Conserved and distinct roles of kreisler in regulation of the paralogous Hoxa-3 and Hoxb-3 genes. Development 126, 759-769.
36. Manzanares, M., Trainor, P. A., Nonchev, S., Ariza-McNaughton, L., Brodie, J., Gould, A., Marshall, H., Morrison, A., Kwan, C-T., Sham, M-H., Wilkinson, D. G. and Krumlauf, R. (1999b). The role of kreisler in segmentation during hindbrain development. Dev. Biol. 211, 220-237.
37. Mark, M., Lufkin, T., Vonesh, J. L., Ruberte, E., Olivo, J. C., Dollé, P., Gorry, P., Lumsden, A. and Chambon, P. (1993). Two rhombomeres are altered in Hoxa-1 mutant mice. Development, 119, 319-338.
38. Mark, M., Ghyselinck, N., Kastner, P., Dupé, V., Wendling, O., Krezel, W., Mascrez, B. and Chambon, P. (1998). Mesectoderm is a major target of retinoic acid action. Eur. J. Oral Sci. 106, 24-31.
39. Marshall, H., Studer, M., Popperl, H., Aparicio, S., Kuroiwa, A., Brenner, S. and Krumlauf, R. (1994). A conserved retinoic acid response element required for early expression of the homeobox gene Hoxb-1. Nature 370, 567-571.
40. Mascrez, B., Mark M., Dierich, A., Ghyselinck, N. B., Kastner, P. and Chambon, P. (1998). The RXRα ligand-dependent activation function 2 (AF-2) is important for mouse development. Development 125, 4691-4707.
41. McKay, I. J., Muchamore, I., Krumlauf, R., Maden, M., Lumsden, A. and Lewis, J. H. (1994). The kreisler mouse: a hindhrain segmentation mutant that lacks two rhombomeres. Development 120, 2199-2211.
42. Mendelsohn, C., Larkin, S., Mark, M., Le Meur, M., Clifford, J., Zelent, A. and Chamhon, P. (1994a). RARβ isoforms: distinct transcriptional control by retinoic acid and specific patterns of promoter activity during mouse embryonic development. Mech. Dev. 45, 227-241
43. Mendelsohn, C., Lohnes, D., Décimo, D., Lufkin, T., LeMeur, M., Chambon, P. and Mark, M. (1994b). Function of the retinoic acid receptors (RARs) during development. II. Multiple abnormalities at various stages of organogenesis in RAR double mutants. Development, 120, 2749-2771.
44. Moens, C. B., Yan, Y. L., Appel, B., Force, A. G. and Kimmel, C. B. (1996). Valentino: a zebrafish gene required for normal hindbrain segmentation. Development 122, 3981-3990.
45. Morrison, A., Ariza-McNaughton, L., Gould, A., Featherstone, M. and Krumlauf, R. (1997). HOXD4 and regulation of the group 4 paralog genes. Development 124, 3135-3146.
46. Murphy, P., Davidson, D. R. and Hill, R. E. (1989). Segment-specific expression of a homeobox-containing gene in the mouse hindbrain. Nature 341, 156-159.
47. Niederreither, K., Subbarayan, V., Dollé, P. and Chambon, P. (1999). Embryonic retinoic acid synthesis is essential for early mouse post-implantation development. Nat. Genet. 21, 444-448.
48. Noden, D. M. (1991) Cell movements and control of patterned tissue assembly during craniofacial development. J. Craniofac. Genet. Dev. Biol. 11, 192-213.
49. Peters, H., Neubuser, A., Kratochwil, K. and Balling, R. (1998). Pax9-deficient mice lack pharyngeal pouch derivatives and teeth and exhibit craniofacial and limb abnormalities. Genes Dev. 12, 2735-2747.
50. Rijli, F. M., Gavalas, A. and Chambon, P. (1998). Segmentation and specification in the branchial region of the head: the role of the Hox selector genes. Int. J. Dev. Biol. 42, 393-401.
51. Ruberte, E., Dollé, P., Chambon, P. and Morriss-Kay, G. (1991). Retinoic acid receptors and cellular retinoid binding proteins. II. Their differential pattern of transcription during early morphogenesis in mouse embryos. Development. 111, 45-60.
52. Schneider-Maunoury, S., Seitanidou, T., Charnay, P. and Lumsden, A. (1997). Segmental and neuronal architecture of the hindbrain of Krox-20 mouse mutants. Development 124, 1215-1226.
53. Schneider-Maunoury, S., Topilko, P., Seitanidou, T., Levi, G., Cohen-Tannoudji, M., Pournin, S., Babinet, C. and Charnay, P. (1993). Disruption of Krox-20 results in alteration of rhombomeres 3 and 5 in the developing hindbrain. Cell 75, 1199-1214.
54. Studer, M., Popperl, H., Marshall, H., Kuroiwa, A. and Krumlauf, R. (1994). Role of a conserved retinoic acid response element in rhombomere restriction of Hoxb-1. Science 265, 1728-1732.
55. Sundin, O. H. and Eichele, G. (1990). A homeo domain protein reveals the metameric nature of the developing chick hindbrain. Genes Dev. 4, 1267-1276.
56. Swiatek, P. J. and Gridley, T. (1993). Perinatal lethality and defects in hindbrain development in mice homozygous for a targeted mutation of the zinc finger gene Krox20. Genes Dev. 7, 2071-2084.
57. Trainor, P. A. and Tam, P. P. L. (1995). Cranial mesoderm and neural crest of the mouse embryo: co-distribution in cranio-facial mesenchyme but distinct segregation in branchial arches. Development 121, 2569-2582.
58. Van der Wees, J., Schilthuis, J. G., Koster, C. H., Diesveld-Schipper, H., Folkers, G. E., van der Saag, P. T., Dawson, M. I., Shudo, K., van der Burg, B. and Durston, A. J. (1998). Inhibition of retinoic acid receptor -mediated signalling alters positional identity in the developing hindbrain. Development 125, 545-556.
59. Waldo, K. L., Kumiski, D. and Kirby, M. (1996). Cardiac neural crest is essential for the persistence rather than the formation of an arch artery. Dev. Dyn. 205, 281-292.
60. Wendung, O., Chambon, P. and Mark, M. (1999). Retinoid X receptors are essential for early mouse development and placentogenesis. Proc. Natl. Acad. Sci. USA 96, 547-551.
61. White, J. C., Shankar, V. N., Highland, M., Epstein, M. L., DeLuca, H. F. and Clagett-Dame, M. (1998). Defects in embryonic hindbrain development and fetal resorption resulting from vitamin A deficiency in the rat are prevented by feeding pharmological levels of all-trans-retinoic acid. Proc. Natl. Acad. Sci. USA 95, 13459-13464.
62. Wilkinson, D. G., Bhatt, S., Chavrier, P., Bravo, R., and Charnay, P. (1989). Segment-specific expression of a zinc-finger gene in the developing nervous system of the mouse. Nature 337, 461-464.
63. Wood, H., Pall, G. and Morriss-Kay, G. (1994). Exposure to retinoic acid before or after the onset of somitogenesis reveals separate effects on rhombomeric segmentation and 3′ HoxB gene expression domains. Development 120, 2279-2285.