The use of a substrate cassette strategy to improve the capacity and throughput of cytochrome P450 induction studies in human hepatocytes

Drug Metabolism and Disposition

Volumn 33, Issue 7, 2005, Pages 920-923

  Mohutsky, Michael A ^a   Petullo, David M ^a   Wrighton, Steven A ^a  

^a ELI LILLY AND COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450; CYTOCHROME P450 1A2; CYTOCHROME P450 2C9; CYTOCHROME P450 3A; DICLOFENAC; MIDAZOLAM; PHENACETIN;

ARTICLE; BIOTRANSFORMATION; CATALYSIS; CELL DIFFERENTIATION; CORRELATION ANALYSIS; ENZYME SUBSTRATE COMPLEX; GENE CASSETTE; HUMAN; HUMAN CELL; LIVER CELL; PRIORITY JOURNAL;

CELLS, CULTURED; CYTOCHROME P-450 ENZYME SYSTEM; ENZYME INDUCTION; HEPATOCYTES; HUMANS; MASS SPECTROMETRY; SUBSTRATE SPECIFICITY;

EID: 22344440846     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: 10.1124/dmd.105.004291     Document Type: Article

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