An assessment of UDP-glucuronosyltransferase induction using primary human hepatocytes

Drug Metabolism and Disposition

Volumn 32, Issue 1, 2004, Pages 140-148

  Soars, Matthew G ^a,b   Petullo, David M ^a   Eckstein, James A ^a   Kasper, Steve C ^a   Wrighton, Steven A ^a  

^a ELI LILLY AND COMPANY   (United States)

^b ASTRAZENECA   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

1 NAPHTHOL; 3 METHYLCHOLANTHRENE; ALPHA NAPHTHOFLAVONE; CARBAMAZEPINE; CYTOCHROME P450 3A2; CYTOCHROME P450 3A4; DEXAMETHASONE; ESTRADIOL; GLUCURONOSYLTRANSFERASE; ISOENZYME; MORPHINE 3 GLUCURONIDE; MORPHINE 6 GLUCURONIDE; MORPHINE DERIVATIVE; OMEPRAZOLE; PHENOBARBITAL; PROPOFOL; RECOMBINANT ENZYME; RIFAMPICIN; TANGERETIN; XENOBIOTIC AGENT;

ARTICLE; DRUG GLUCURONIDATION; ENZYME INDUCTION; ENZYME MECHANISM; ENZYME SPECIFICITY; ENZYME SUBSTRATE; HUMAN; HUMAN CELL; LIVER CELL; PRIORITY JOURNAL;

ADOLESCENT; ADULT; AGED; CELLS, CULTURED; CHILD; CHILD, PRESCHOOL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYTOCHROME P-450 CYP1A1; CYTOCHROME P-450 CYP1A2; CYTOCHROME P-450 ENZYME SYSTEM; ENZYME INDUCTION; ESTRADIOL; FEMALE; GLUCURONIDES; GLUCURONOSYLTRANSFERASE; HEPATOCYTES; HUMANS; HYDROXYTESTOSTERONES; ISOENZYMES; MALE; MASS SPECTROMETRY; MIDDLE AGED; MORPHINE; NAPHTHOLS; PROPOFOL; RECOMBINANT PROTEINS; SUBSTRATE SPECIFICITY;

EID: 1642579667     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: 10.1124/dmd.32.1.140     Document Type: Article

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