Sphingosine-1-phosphate induces a PDGFR-dependent cell detachment via inhibiting β1 integrin in HEK293 cells

FEBS Letters

Volumn 579, Issue 18, 2005, Pages 3899-3906

  Zaslavsky, Alexander ^a,b   Li, Song ^a,c   Xu, Yan ^a,b  

^a LERNER RESEARCH INSTITUTE   (United States)

^b CLEVELAND STATE UNIVERSITY   (United States)

^c CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

1 integrin; Cell detachment; Extracellular matrix; Inside out inhibition; Platelet derived growth factor receptor; Sphingosine 1 phosphate

Indexed keywords

6,7 DIMETHOXY 2 PHENYLQUINOXALINE; BETA1 INTEGRIN; EPIDERMAL GROWTH FACTOR RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PLATELET DERIVED GROWTH FACTOR RECEPTOR; PROTEIN INHIBITOR; SPHINGOSINE 1 PHOSPHATE;

ARTICLE; CELL ADHESION; CELL STRAIN HEK293; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVATION; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; MOLECULE; PRIORITY JOURNAL; PROTEIN FUNCTION;

ANTIGENS, CD29; BLOTTING, WESTERN; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; EXTRACELLULAR MATRIX; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; HUMANS; INTEGRINS; LAMININ; LYSOPHOSPHOLIPIDS; MODELS, BIOLOGICAL; PHOSPHORYLATION; RECEPTORS, PLATELET-DERIVED GROWTH FACTOR; SIGNAL TRANSDUCTION; SPHINGOSINE; TRANSFECTION; TYRPHOSTINS; VITRONECTIN;

EID: 21844456516     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2005.06.006     Document Type: Article

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