Platinum cross-linking of adenines and guanines on the quadruplex structures of the AG3(T2AG3)3 and (T2AG3)4 human telomere sequences in Na+ and K+ solutions

Nucleic Acids Research

Volumn 31, Issue 6, 2003, Pages 1605-1613

  Redon, Sophie ^a   Bombard, Sophie ^a   Elizondo Riojas, Miguel Angel ^a,b   Chottard, Jean Claude ^a  

^a UNIVERSITÉ PARIS DESCARTES   (France)

^b HOSPITAL UNIVERSITARIO DR JOSÉ ELEUTERIO GONZÁLEZ   (Mexico)

Author keywords

[No Author keywords available]

Indexed keywords

ADENINE; CISPLATIN; DNA BASE; EXONUCLEASE; GUANINE; PLATINUM DERIVATIVE; POTASSIUM ION; SODIUM ION; TELOMERASE;

CHELATION; CIS TRANS ISOMERISM; COMPLEX FORMATION; CONTROLLED STUDY; COVALENT BOND; DENATURING GRADIENT GEL ELECTROPHORESIS; DNA BASE COMPOSITION; DNA CROSS LINKING; DNA SEQUENCE; DNA STRUCTURE; ENZYME DEGRADATION; ENZYME INHIBITION; HUMAN; ISOLATION PROCEDURE; NUCLEAR MAGNETIC RESONANCE; NUCLEIC ACID ANALYSIS; PRIORITY JOURNAL; REVIEW; TELOMERE; X RAY CRYSTALLOGRAPHY;

ADENINE; BASE SEQUENCE; BINDING SITES; CROSS-LINKING REAGENTS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GUANINE; HUMANS; NUCLEIC ACID CONFORMATION; OLIGONUCLEOTIDES; PLATINUM; POTASSIUM; REPETITIVE SEQUENCES, NUCLEIC ACID; SODIUM; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; TELOMERE;

EID: 0037443979     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/gkg259     Document Type: Review

References (26)

1. Makarov,V.L., Hirose,Y. and Langmore,J.P. (1997) Long G tails at both ends of human chromosomes suggest a C strand degradation mechanism for telomere shortening. Cell, 88, 657-666.
2. Wang,Y. and Patel,D.J. (1993) Solution structure of the human telomeric repeat d[AG3(T2AG3)3] G-tetraplex. Structure, 1, 263-282.
3. Parkinson,G.N., Lee,M.P. and Neidle,S. (2002) Crystal structure of parallel quadruplexes from human telomeric DNA. Nature, 417, 876-880.
4. Redon,S., Bombard,S., Elizondo-Riojas,M.A. and Chottard,J.C. (2001) Platination of the (T2G4)4 telomeric sequence: a structural and cross-linking study. Biochemistry, 40, 8463-8470.
5. Martin,R.B. (1999) Platinum complexes: hydrolysis and binding to N(7) and N(1) of purines. In Lippert,B. (ed.), Cisplatin. Chemistry and Biochemistry of a Leading Anticancer Drug. Wiley-VCH, Zürick, pp. 183-206.
6. Patel,D.J. (2002) Structural biology: a molecular propeller. Nature, 417, 807-808.
7. Ishibashi,T. and Lippard,S.J. (1998) Telomere loss in cells treated with cisplatin. Proc. Natl Acad. Sci. USA, 95, 4219-4223.
8. Burger,A.M., Double,J.A. and Newell,D.R. (1997) Inhibition of telomerase activity by cisplatin in human testicular cancer cells. Eur. J. Cancer, 33, 638-644.
9. Burstyn,J.N., Heiger-Bernays,W.J., Cohen,S.M. and Lippard,S.J. (2000) Formation of cis-diamminedichloroplatinum(II) 1,2-intrastrand cross-links on DNA is flanking-sequence independent. Nucleic Acids Res., 28, 4237-4243.
10. Fedoroff,O.Y., Salazar,M., Han,H., Chemeris,V.V., Kerwin,S.M. and Hurley,L.H. (1998) NMR-based model of a telomerase-inhibiting compound bound to G-quadruplex DNA. Biochemistry, 37, 12367-12374.
11. Perry,P.J., Gowan,S.M., Reszka,A.P., Polucci,P., Jenkins,T.C., Kelland,L.R. and Neidle,S. (1998) 1,4- and 2,6-disubstituted amidoanthracene-9,10-dione derivatives as inhibitors of human telomerase. J. Med. Chem., 41, 3253-3260.
12. Perry,P.J., Read,M.A., Davies,R.T., Gowan,S.M., Reszka,A.P., Wood,A.A., Kelland,L.R. and Neidle,S. (1999) 2,7-Disubstituted amidofluorenone derivatives as inhibitors of human telomerase. J. Med. Chem., 42, 2679-2684.
13. Han,F.X.G., Wheelhouse,R.T. and Hurley,L.H. (1999) Interactions of TMPyP4 and TMPyP2 with quadruplex DNA. Structural basis for the differential effects on telomerase inhibition. J. Am. Chem. Soc., 121, 3561-3570.
14. Mergny,J.L., Lacroix,L., Teulade-Fichou,M.P., Hounsou,C., Guittat,L., Hoarau,M., Arimondo,P.B., Vigneron,J.P., Lehn,J.M., Riou,J.F., Garestier,T. and Hélène,C. (2001) Telomerase inhibitors based on quadruplex ligands selected by a fluorescence assay. Proc. Natl Acad. Sci. USA, 98, 3062-3067.
15. Izbicka,E., Wheelhouse,R.T., Raymond,E., Davidson,K.K., Lawrence,R.A., Sun,D.Y., Windle,B.E., Hurley,L.H. and Von Hoff,D.D. (1999) Effects of cationic porphyrins as G-quadruplex interactive agents in human tumor cells. Cancer Res., 59, 639-644.
16. Riou,J.F., Guittat,L., Mailliet,P., Laoui,A., Renou,E., Petitgenet,O., Megnin-Chanet,F., Helene,C. and Mergny,J.L. (2002) Cell senescence and telomere shortening induced by a new series of specific G-quadruplex DNA ligands. Proc. Natl Acad. Sci. USA, 99, 2672-2677.
17. Nielsen,P.E. (1990) Chemical and photochemical probing of DNA complexes. J. Mol. Recognit., 3, 1-25.
18. 2+ by enzymatic degradation of the products and ESI and MALDI mass spectrometries. J. Mass Spectrom., 31, 802-809.
19. Coste,F., Malinge,J.M., Serre,L., Shepard,W., Roth,M., Leng,M. and Zelwer,C. (1999) Crystal structure of a double-stranded DNA containing a cisplatin interstrand cross-link at 1.63 Å resolution: hydration at the platinated site. Nucleic Acids Res., 27, 1837-1846.
20. Paquet,F., Boudvillain,M., Lancelot,G. and Leng,M. (1999) NMR solution structure of a DNA dodecamer containing a transplatin interstrand GN7-CN3 cross-link. Nucleic Acids Res., 27, 4261-4268.
21. Mikola,M. and Arpalahti,J. (1994) Kinetics and mechanism of the complexation of trans-diamminedichloroplatinum(II) with the purine nucleoside inosine in aqueous solution. Inorg. Chem., 43, 4439-4445.
22. Brabec,V. and Leng,M. (1993) DNA interstrand cross-links of trans-diamminedichloroplatinum(II) are preferentially formed between guanine and complementary cytosine residues. Proc. Natl Acad. Sci. USA, 90, 5345-5349.
23. Bernal-Mendez,E., Boudvillain,M., Gonzalez-Vilchez,F. and Leng,M. (1997) Chemical versatility of transplatin monofunctional adducts within multiple site-specifically platinated DNA. Biochemistry, 36, 7281-7287.
24. 2+-dependent ribozyme by means of platinum complexes. Eur. J. Biochem., 252,. 25-35.
25. Escaffre,M., Favre,A., Chottard,J.C. and Bombard,S. (2002) Determination of platinated purines in oligoribonucleotides by limited digestion with ribonucleases T1 and U2. Anal. Biochem., 310, 42-49.
26. Balagurumoorthy,P. and Brahmachari,S.K. (1994) Structure and stability of human telomeric sequence. J. Biol. Chem., 269, 21858-21869.