Endocrine and exocrine secretion of leptin by the gastric mucosa

Journal of Histochemistry and Cytochemistry

Volumn 53, Issue 7, 2005, Pages 851-860

  Cammisotto, Philippe G ^a   Renaud, Christian ^a   Gingras, Diane ^a   Delvin, Edgard ^a   Levy, Emile ^a   Bendayan, Moïse ^a  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

Endocrine secretion; Exocrine secretion; Gastric mucosa; Intestine; Leptin; Leptin receptors

Indexed keywords

LEPTIN; LEPTIN RECEPTOR; PEPSINOGEN;

ANIMAL TISSUE; ARTICLE; BASOLATERAL MEMBRANE; CELL MEMBRANE; CELL ULTRASTRUCTURE; CONTROLLED STUDY; DIGESTIVE SYSTEM; ENDOCRINE CELL; EPITHELIUM CELL; EXOCRINE SECRETION; GOLGI COMPLEX; HORMONE RECEPTOR INTERACTION; HORMONE RELEASE; IMMUNOCYTOCHEMISTRY; IMMUNOELECTRON MICROSCOPY; IMMUNOGOLD LABELING; INTESTINE CELL; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; ROUGH ENDOPLASMIC RETICULUM; SECRETORY GRANULE; STOMACH CHIEF CELL; STOMACH MUCOSA;

ANIMALS; CELL MEMBRANE; CHIEF CELLS, GASTRIC; ENTEROCYTES; ENTEROENDOCRINE CELLS; GASTRIC MUCOSA; IMMUNOHISTOCHEMISTRY; INTESTINE, SMALL; LEPTIN; MALE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, CELL SURFACE;

EID: 21544456365     PISSN: 00221554     EISSN: None     Source Type: Journal    
DOI: 10.1369/jhc.5A6620.2005     Document Type: Article

References (48)

1. Ahima RS, Osei SY (2004) Leptin signaling. Physiol Behav 81:223-241
2. Ahima RS, Saper CB, Flier JS, Elmquist JK (2000) Leptin regulation of neuroendocrine systems. Front Neuroendocrinol 21:263-307
3. Alavi K, Schwartz MZ, Prasad R, O'Connor D, Funanage V (2002) Leptin: a new growth factor for the small intestine. J Pediatr Surg 37:327-330
4. Attoub S, Noe V, Pirola L, Bruyneel E, Chastre E, Mareel M, Wymann MP, et al. (2000) Leptin promotes invasiveness of kidney and colonic epithelial cells via phosphoinositide 3-kinase-, rho-, and rac-dependent signaling pathways. FASEB J 14:2329-2338
5. Bado A, Levasseur S, Attoub S, Kermorgant S, Laigneau JP, Bortoluzzi MN, Moizo L, et al. (1998) The stomach is a source of leptin. Nature 394:790-793
6. Ballinger A (1999) Gastric leptin. Gut 44:153-154
7. Barbier M, Attoub S, Galmiche JP. Leptin: physiological aspects and implications in hepato-gastroenterology (2000) Gastroenterol Clin Biol 24:506-519
8. Barrenetxe J, Villaro AC, Guembe L, Pascual I, Munoz-Navas M, Barber A, Lostao MP (2002) Distribution of the long leptin receptor isoform in brush border, basolateral membrane, and cytoplasm of enterocytes. Gut 50:797-802
9. Bendayan M (1995) Colloidal gold post-embedding immunocytochemistry. Prog Histochem Cytochem 29:1-159
10. Bjorbaek C, Kahn BB (2004) Leptin signaling in the central nervous system and the periphery. Recent Prog Horm Res 59:305-331
11. Bjorbaek C, Uotani S, da Silva B, Flier JS (1997) Divergent signaling capacities of the long and short isoforms of the leptin receptor. J Biol Chem 272:32686-32695
12. Bruneau N, Lombardo D, Levy E, Bendayan M (2000) Roles of molecular chaperones in pancreatic secretion and their involvement in intestinal absorption. Microsc Res Tech 49:329-345
13. Brzozowski T, Konturek PC, Konturek SJ, Pajdo R, Duda A, Pierzchalski P, Bielanski W, et al. (1999) Leptin in gastroprotection induced by cholecystokinin or by a meal. Role of vagal and sensory nerves and nitric oxide. Eur J Pharmacol 374:263-276
14. Brzozowski T, Konturek PC, Konturek SJ, Pierzchalski P, Bielanski W, Pajdo R, Drozdowicz D, et al. (2000) Central leptin and cholecystokinin in gastroprotection against ethanol-induced damage. Digestion 62:126-142
15. Buyse M, Aparicio T, Guilmeau S, Goiot H, Sobhani I, Bado A (2004) Paracrine actions of the stomach-derived leptin. Med Sci (Paris) 20:183-188
16. Buyse M, Berlioz F, Guilmeau S, Tsocas A, Voisin T, Peranzi G, Merlin D, et al. (2001) PepT1-mediated epithelial transport of dipeptides and cephalexin is enhanced by luminal leptin in the small intestine. J Clin Invest 108:1483-1494
17. Cammisotto PG, Bukowiecki LJ (2004) Role of calcium in the secretion of leptin from white adipocytes. Am J Physiol Regul Integr Comp Physiol 287:R1380-R1386
18. Cinti S, De Matteis R, Pico C, Ceresi E, Obrador A, Maffeis C, Oliver J, et al. (2000) Secretory granules of endocrine and Chief cells of human stomach mucosa contain leptin. Int J Obes 24: 789-793
19. Dube N, Delvin E, Yotov W, Garofalo C, Bendayan M, Veerkamp JH, Levy E (2001) Modulation of intestinal and liver fatty acid-binding proteins in Caco-2 cells by lipids, hormones and cytokines. J Cell Biochem 81:613-620
20. Fei H, Okano HJ, Li C, Lee GH, Zhao C, Darnell R, Friedman JM (1997) Anatomic localization of alternatively spliced leptin receptors (Ob-R) in mouse brain and other tissues. Proc Natl Acad Sci USA 94:7001-7005
21. Friedman JM, Halaas JL (1998) Leptin and the regulation of body weight in mammals. Nature 395:763-770
22. Gettys TW, Harkness PJ, Watson PM (1996) The beta 3-adrenergic receptor inhibits insulin-stimulated leptin secretion from isolated rat adipocytes. Endocrinology 137:4054-4057
23. Goiot H, Attoub S, Kermorgant S, Laigneau JP, Lardeux B, Lehy T, Lewin MJ, et al. (2001) Antral mucosa expresses functional leptin receptors coupled to STAT-3 signaling, which is involved in the control of gastric secretions in the rat. Gastroenterology 121: 1417-1427
24. Guilmeau S, Buyse M, Bado A (2004) Gastric leptin: a new manager of gastrointestinal function. Curr Opin Pharmacol 4:561-566
25. Guilmeau S, Buyse M, Tsocas A, Laigneau JP, Bado A (2003) Duodenal leptin stimulates cholecystokinin secretion: evidence of a positive leptin-cholecystokinin feedback loop. Diabetes 52: 1664-1672
26. Havel PJ (2000) Role of adipose tissue in body-weight regulation: mechanisms regulating leptin production and energy balance. Proc Nutr Soc 59:359-371
27. Hervey GR (1959) The effects of lesions in the hypothalamus in parabiotic rats. J Physiol 145:336-352
28. Himms-Hagen J (1999) Physiological roles of the leptin endocrine system: differences between mice and humans. Crit Rev Clin Lab Sci 36:575-655
29. Kennedy GC (1953) The role of depot fat in the hypothalamic control of food intake in the rat. Proc R Soc Lond B Biol Sci 140: 578-596
30. Konturek PC, Brzozowski T, Meixner H, Ptak A, Hahn EG, Konturek SJ (2001) Central and peripheral neural aspects of gastroprotective and ulcer healing effects of lipopolysaccharides. J Physiol Pharmacol 52:611-623
31. Lee GH, Proenca R, Montez JM, Carroll KM, Darvishzadeh JG, Lee JI, Friedman JM (1996) Abnormal splicing of the leptin receptor in diabetic mice. Nature 379:632-635
32. Levy, JR, Stevens W (2001) The effects of insulin, glucose and, pyruvat on the kinetics of leptin secretion. Endocrinology 142:3558-3562
33. Liu M, Doi T, Tso P (2003) Regulation of intestinal and hypothalamic apolipoprotein A-IV. Exp Biol Med (Maywood) 228: 1181-1189
34. Liu C, Liu XJ, Barry G, Ling N, Maki RA, De Souza EB (1997) Expression and characterization of a putative high affinity human soluble leptin receptor. Endocrinology 138:3548-3554
35. Lostao MP, Urdaneta E, Martinez-Anso E, Barber A, Martinez JA (1998) Presence of leptin receptors in rat small intestine and leptin effect on sugar absorption. FEBS Lett 423:302-306
36. Masuzaki H, Ogawa Y, Sagawa N, Hosoda K, Matsumoto T, Mise H, Nishimura H, et al. (1997) Nonadipose tissue production of leptin: leptin as a novel placenta-derived hormone in humans. Nat Med 3:1029-1033
37. Mercer JG, Hoggard N, Williams LM, Lawrence CB, Hannah LT, Morgan PJ, Trayhurn P (1996) Coexpression of leptin receptor and preproneuropeptide Y mRNA in arcuate nucleus of mouse hypothalamus. J Neuroendocrinol 8:733-735
38. Mix H, Widjaja A, Jandl O, Cornberg M, Kaul A, Goke M, Beil W, et al. (2000) Expression of leptin and leptin receptor isoforms in the human stomach. Gut 47:481-486
39. Morton NM, Emilsson V, Liu YL, Cawthorne MA (1998) Leptin action in intestinal cells. J Biol Chem 273:26194-26201
40. Pearson PY, O'Connor DM, Schwartz MZ (2001) Novel effect of leptin on small intestine adaptation. J Surg Res 97:192-195
41. Siegmund B, Lehr HA, Fantuzzi G (2002) Leptin: a pivotal mediator of intestinal inflammation in mice. Gastroenterology 122:2011-2025
42. Sobhani I, Bado A, Vissuzaine C, Buyse M, Kermorgant S, Laigneau JP, Attoub S, et al. (2000) Leptin secretion and leptin receptor in the human stomach. Gut 47:178-183
43. Sobhani I, Buyse M, Goiot H, Weber N, Laigneau JP, Henin D, Soul JC, et al. (2002) Vagal stimulation rapidly increases leptin secretion in human stomach. Gastroenterology 122:259-263
44. Stan S, Levy E, Bendayan M, Zoltowska M, Lambert M, Michaud J, Asselin C, et al. (2001) Effect of human recombinant leptin on lipid handling by fully differentiated Caco-2 cells. FEBS Lett 508: 80-84
45. Wilkinson M, Morash B, Ur E (2000) The brain is a source of leptin. Front Horm Res 26:106-125
46. Tartaglia LA, Dembski M, Weng X, Deng N, Culpepper J, Devos R, Richards GJ, et al. (1995) Identification and expression cloning of a leptin receptor, OB-R. Cell 83:1263-1271
47. Wynne K, Stanley S, Bloom S (2004) The gut and regulation of body weight. J Clin Endocrinol Metab 89:2576-2582
48. Zhang Y, Proenca R, Maffei M, Barone M, Leopold L, Friedman JM (1994) Positional cloning of the mouse obese gene and its human homologue. Nature 372:425-432