메뉴 건너뛰기




Volumn 22, Issue 5, 2004, Pages 615-621

Microarray reality checks in the context of a complex disease

Author keywords

[No Author keywords available]

Indexed keywords

GENE EXPRESSION; GENE SET; MICROARRAYS;

EID: 2342624566     PISSN: 10870156     EISSN: None     Source Type: Journal    
DOI: 10.1038/nbt965     Document Type: Review
Times cited : (142)

References (94)
  • 1
    • 0013219175 scopus 로고    scopus 로고
    • The Chipping Forecast II
    • The Chipping Forecast II. Nature Genet. 32 (Suppl.), 465-552 (2002).
    • (2002) Nature Genet. , vol.32 , Issue.SUPPL. , pp. 465-552
  • 2
    • 2342559636 scopus 로고    scopus 로고
    • Progress in antibody arrays
    • Taussig, M.J. & Landegren, U. Progress in antibody arrays. Targets 2, 169-176 (2003).
    • (2003) Targets , vol.2 , pp. 169-176
    • Taussig, M.J.1    Landegren, U.2
  • 3
    • 0035799654 scopus 로고    scopus 로고
    • Microarrays of cells expressing defined cDNAs
    • Ziauddin, J. & Sabatini, D.M. Microarrays of cells expressing defined cDNAs. Nature 411, 107-110 (2001).
    • (2001) Nature , vol.411 , pp. 107-110
    • Ziauddin, J.1    Sabatini, D.M.2
  • 4
    • 1642349616 scopus 로고    scopus 로고
    • Gene expression tests foretell breast cancer's future
    • Garber, K. Gene expression tests foretell breast cancer's future. Science 303, 1754-1755 (2004).
    • (2004) Science , vol.303 , pp. 1754-1755
    • Garber, K.1
  • 5
    • 1242351300 scopus 로고    scopus 로고
    • Statistical analysis of global gene expression data: Some practical considerations
    • Holzman, T. & Kolker, E. Statistical analysis of global gene expression data: some practical considerations. Curr. Opin. Biotechnol. 15, 52-57 (2004).
    • (2004) Curr. Opin. Biotechnol. , vol.15 , pp. 52-57
    • Holzman, T.1    Kolker, E.2
  • 6
    • 1342287336 scopus 로고    scopus 로고
    • Making sense of lung-cancer gene-expression profiles
    • Wigle, D., Tsao, M. & Jurisica, I. Making sense of lung-cancer gene-expression profiles. Genome Biol. 5, 309 (2004).
    • (2004) Genome Biol. , vol.5 , pp. 309
    • Wigle, D.1    Tsao, M.2    Jurisica, I.3
  • 8
    • 0032850094 scopus 로고    scopus 로고
    • A unitary model of schizophrenia. Bleuler's "fragmented Phrene" as schizencephaly
    • Andreasen, N.C. A unitary model of schizophrenia. Bleuler's "fragmented Phrene" as schizencephaly. Arch. Gen. Psychiatry 56, 781-787 (1999).
    • (1999) Arch. Gen. Psychiatry , vol.56 , pp. 781-787
    • Andreasen, N.C.1
  • 9
    • 0029119737 scopus 로고
    • Chemical brain anatomy in schizophrenia
    • Sedvall, G. & Farde, L. Chemical brain anatomy in schizophrenia. Lancet 346, 743-749 (1995).
    • (1995) Lancet , vol.346 , pp. 743-749
    • Sedvall, G.1    Farde, L.2
  • 10
    • 0032924127 scopus 로고    scopus 로고
    • The neuropathology of schizophrenia. A critical review of the data and their interpretation
    • Harrison, P.J. The neuropathology of schizophrenia. A critical review of the data and their interpretation. Brain 122, 593-624 (1999).
    • (1999) Brain , vol.122 , pp. 593-624
    • Harrison, P.J.1
  • 11
    • 0033135818 scopus 로고    scopus 로고
    • MRI anatomy of schizophrenia
    • McCarley, R.W. et al. MRI anatomy of schizophrenia. Biol. Psychiatry 45, 1099-1119 (1999).
    • (1999) Biol. Psychiatry , vol.45 , pp. 1099-1119
    • McCarley, R.W.1
  • 12
    • 0034062074 scopus 로고    scopus 로고
    • Schizophrenia; the fundamental questions
    • Andreasen, N.C. Schizophrenia; the fundamental questions. Brain Res. Rev 31, 106-112 (2000).
    • (2000) Brain Res. Rev. , vol.31 , pp. 106-112
    • Andreasen, N.C.1
  • 14
    • 0035671763 scopus 로고    scopus 로고
    • Review of immunological and immunopathological findings in schizophrenia
    • Rothermundt, M., Arolt, V. & Bayer, T.A. Review of immunological and immunopathological findings in schizophrenia. Brain Behav. Immun. 15, 319-339 (2001).
    • (2001) Brain Behav. Immun. , vol.15 , pp. 319-339
    • Rothermundt, M.1    Arolt, V.2    Bayer, T.A.3
  • 15
    • 0035836737 scopus 로고    scopus 로고
    • Retroviral RNA identified in the cerebrospinal fluids and brains of individuals with schizophrenia
    • Karlsson, H. et al. Retroviral RNA identified in the cerebrospinal fluids and brains of individuals with schizophrenia. Proc. Natl. Acad. Sci. USA 98, 4634-4639 (2001).
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 4634-4639
    • Karlsson, H.1
  • 16
    • 0142244688 scopus 로고    scopus 로고
    • Schizophrenia
    • Freedman, R. Schizophrenia. N. Engl. J. Med. 349, 1738-1749 (2003).
    • (2003) N. Engl. J. Med. , vol.349 , pp. 1738-1749
    • Freedman, R.1
  • 17
    • 0041510158 scopus 로고    scopus 로고
    • The functional neuroanatomy of schizophrenic subsyndromes
    • Honey, G.D. et al. The functional neuroanatomy of schizophrenic subsyndromes. Psychol. Med. 33, 1007-1018 (2003).
    • (2003) Psychol. Med. , vol.33 , pp. 1007-1018
    • Honey, G.D.1
  • 18
    • 0035836642 scopus 로고    scopus 로고
    • Genome-wide expression analysis reveals dysregulation of myelination-related genes in chronic schizophrenia
    • Hakak, Y. et al. Genome-wide expression analysis reveals dysregulation of myelination-related genes in chronic schizophrenia. Proc. Natl. Acad. Sci. USA 98, 4746-4751 (2001).
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 4746-4751
    • Hakak, Y.1
  • 19
    • 0033637841 scopus 로고    scopus 로고
    • Molecular characterization of schizophrenia viewed by microarray analysis of gene expression in prefrontal cortex
    • Mimics, K., Middleton, F.A., Marquez, A., Lewis, D.A. & Levitt, P. Molecular characterization of schizophrenia viewed by microarray analysis of gene expression in prefrontal cortex. Neuron 28, 53-67 (2000).
    • (2000) Neuron , vol.28 , pp. 53-67
    • Mimics, K.1    Middleton, F.A.2    Marquez, A.3    Lewis, D.A.4    Levitt, P.5
  • 20
    • 0035878139 scopus 로고    scopus 로고
    • Application of cDNA microarrays to examine gene expression differences in schizophrenia
    • Vawter, M.P. et al. Application of cDNA microarrays to examine gene expression differences in schizophrenia. Brain Res. Bull. 55, 641-650 (2001).
    • (2001) Brain Res. Bull. , vol.55 , pp. 641-650
    • Vawter, M.P.1
  • 21
    • 18344369874 scopus 로고    scopus 로고
    • Gene expression analysis in schizophrenia: Reproducible upregulation of several members of the apolipoprotein L family located in a high-susceptibility focus for schizophrenia on chromosome 22
    • Mimmack, M.L. et al. Gene expression analysis in schizophrenia: reproducible upregulation of several members of the apolipoprotein L family located in a high-susceptibility focus for schizophrenia on chromosome 22. Proc. Natl. Acad. Sci. USA 99, 4680-4685 (2002).
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 4680-4685
    • Mimmack, M.L.1
  • 22
    • 0036550998 scopus 로고    scopus 로고
    • Gene expression profiling reveals alterations of specific metabolic pathways in schizophrenia
    • Middleton, F.A., Mimics, K., Pierri, J.N., Lewis, D.A. & Levitt, P. Gene expression profiling reveals alterations of specific metabolic pathways in schizophrenia. J. Neurosci. 22, 2718-2729 (2002).
    • (2002) J. Neurosci. , vol.22 , pp. 2718-2729
    • Middleton, F.A.1    Mimics, K.2    Pierri, J.N.3    Lewis, D.A.4    Levitt, P.5
  • 23
    • 0036807851 scopus 로고    scopus 로고
    • Gene expression profiling with DNA microarrays: Advancing our understanding of psychiatric disorders
    • Pongrac, J., Middleton, F.A., Lewis, D.A., Levitt, P. & Mimics, K. Gene expression profiling with DNA microarrays: advancing our understanding of psychiatric disorders. Neurochem. Res. 27, 1049-1063 (2002).
    • (2002) Neurochem. Res. , vol.27 , pp. 1049-1063
    • Pongrac, J.1    Middleton, F.A.2    Lewis, D.A.3    Levitt, P.4    Mimics, K.5
  • 24
    • 0033759439 scopus 로고    scopus 로고
    • Decrease in reelin and glutamic acid decarboxylase 67 (GAD67) expression in schizophrenia and bipolar disorder
    • Guidotti, A. et al. Decrease in reelin and glutamic acid decarboxylase 67 (GAD67) expression in schizophrenia and bipolar disorder. Arch. Gen. Psychiatry 57, 1061-1069 (2000).
    • (2000) Arch. Gen. Psychiatry , vol.57 , pp. 1061-1069
    • Guidotti, A.1
  • 25
    • 0034255025 scopus 로고    scopus 로고
    • Subnucleus-specific loss of neurons in medial thalamus of schizophrenics
    • Popken, G.J., Bunney, W.E., Potkin, S.G. & Jones, E.G. Subnucleus-specific loss of neurons in medial thalamus of schizophrenics. Proc. Natl. Acad. Sci. USA 97, 9276-9280 (2000).
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 9276-9280
    • Popken, G.J.1    Bunney, W.E.2    Potkin, S.G.3    Jones, E.G.4
  • 26
    • 0035949688 scopus 로고    scopus 로고
    • Mapping adolescent brain change reveals dynamic wave of accelerated grey matter loss in very early-onset schizophrenia
    • Thompson, P.M. et al. Mapping adolescent brain change reveals dynamic wave of accelerated grey matter loss in very early-onset schizophrenia. Proc. Natl. Acad. Sci. USA 98, 11650-11655 (2001).
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 11650-11655
    • Thompson, P.M.1
  • 27
    • 0029160963 scopus 로고
    • Cytoarchitectonic definition of prefrontal areas in the normal human cortex: II. Variability in locations of areas 9 and 46 and relationship to the Talairach coordinate system
    • Rajkowska, G. & Goldman-Rakic, P.S. Cytoarchitectonic definition of prefrontal areas in the normal human cortex: II. Variability in locations of areas 9 and 46 and relationship to the Talairach coordinate system. Cereb. Cortex 5, 323-337 (1995).
    • (1995) Cereb. Cortex , vol.5 , pp. 323-337
    • Rajkowska, G.1    Goldman-Rakic, P.S.2
  • 28
    • 0027440223 scopus 로고
    • Significant reductions in synapsin but not synaptophysin specific activity in the brains of some schizophrenics
    • Browning, M.D., Dudek, E.M., Rapier, J.L., Leonard, S. & Freedman, R. Significant reductions in synapsin but not synaptophysin specific activity in the brains of some schizophrenics. Biol. Psychiatry 34, 529-535 (1993).
    • (1993) Biol. Psychiatry , vol.34 , pp. 529-535
    • Browning, M.D.1    Dudek, E.M.2    Rapier, J.L.3    Leonard, S.4    Freedman, R.5
  • 29
    • 0034977822 scopus 로고    scopus 로고
    • Failure to confirm NOTCH4 association with schizophrenia in a large population-based sample from Scotland
    • McGinnis, R.E. et al. Failure to confirm NOTCH4 association with schizophrenia in a large population-based sample from Scotland. Nature Genet. 28, 128-129 (2001).
    • (2001) Nature Genet. , vol.28 , pp. 128-129
    • McGinnis, R.E.1
  • 30
    • 0034011252 scopus 로고    scopus 로고
    • Decreased glutamic acid decarboxylase67 messenger RNA expression in a subset of prefrontal cortical γ-aminobutyric acid neurons in subjects with schizophrenia
    • Volk, D.W., Austin, M.C., Pierri, J.N., Sampson, A.R. & Lewis, D.A. Decreased glutamic acid decarboxylase67 messenger RNA expression in a subset of prefrontal cortical γ-aminobutyric acid neurons in subjects with schizophrenia. Arch. Gen. Psychiatry 57, 237-245 (2000).
    • (2000) Arch. Gen. Psychiatry , vol.57 , pp. 237-245
    • Volk, D.W.1    Austin, M.C.2    Pierri, J.N.3    Sampson, A.R.4    Lewis, D.A.5
  • 31
    • 0037171087 scopus 로고    scopus 로고
    • Hippocampal expression of the calcium sensor protein visinin-like protein-1 in schizophrenia
    • Bernstein, H.-G.C.A. et al. Hippocampal expression of the calcium sensor protein visinin-like protein-1 in schizophrenia. Neuroreport 13, 393-396 (2002).
    • (2002) Neuroreport , vol.13 , pp. 393-396
    • Bernstein, H.-G.C.A.1
  • 32
    • 0036356994 scopus 로고    scopus 로고
    • Assessment of the relationship between signal intensities and transcript concentration for Affymetrix GeneChip arrays
    • research0005.1z-0005.10
    • Chudin, E. et al. Assessment of the relationship between signal intensities and transcript concentration for Affymetrix GeneChip arrays. Genome Biol. 3, research0005.1z-0005.10 (2001).
    • (2001) Genome Biol. , vol.3
    • Chudin, E.1
  • 33
    • 0036900895 scopus 로고    scopus 로고
    • Fundamentals of experimental design for cDNA microarrays
    • Churchill, G.A. Fundamentals of experimental design for cDNA microarrays. Nature Genet. 32 suppl. Suppl., 490-495 (2002).
    • (2002) Nature Genet. , vol.32 , Issue.SUPPL. , pp. 490-495
    • Churchill, G.A.1
  • 35
    • 0036211063 scopus 로고    scopus 로고
    • Analysis of matched mRNA measurements from two different microarray technologies
    • Kuo, W.P. et al. Analysis of matched mRNA measurements from two different microarray technologies. Bioinformatics 18, 405-412 (2002).
    • (2002) Bioinformatics , vol.18 , pp. 405-412
    • Kuo, W.P.1
  • 36
    • 0036773278 scopus 로고    scopus 로고
    • Differential gene expression patterns revealed by oligonucleatide versus long cDNA arrays
    • Li, J., Pankratz, M. & Johnson, J.A. Differential gene expression patterns revealed by oligonucleatide versus long cDNA arrays. Toxicol. Sci. 69, 383-390 (2002).
    • (2002) Toxicol. Sci. , vol.69 , pp. 383-390
    • Li, J.1    Pankratz, M.2    Johnson, J.A.3
  • 37
    • 0038486795 scopus 로고    scopus 로고
    • Spotted long oligonucleotide arrays for human gene expression analysis
    • Barczak, A. et al. Spotted long oligonucleotide arrays for human gene expression analysis. Genome Res. 13, 1775-1785 (2003).
    • (2003) Genome Res. , vol.13 , pp. 1775-1785
    • Barczak, A.1
  • 38
    • 0842321044 scopus 로고    scopus 로고
    • Normalization and analysis of cDNA microarrays using within-array replications applied to neuroblastoma cell response to a cytokine
    • Fan, J., Tam, P., Vande Woude, G. & Ren, Y. Normalization and analysis of cDNA microarrays using within-array replications applied to neuroblastoma cell response to a cytokine. Proc. Natl. Acad. Sci. USA 101, 1135-1140 (2004).
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 1135-1140
    • Fan, J.1    Tam, P.2    Vande Woude, G.3    Ren, Y.4
  • 39
    • 4244098036 scopus 로고    scopus 로고
    • A new approach for filtering noise from high-density oligonucleotide microarray datasets
    • Mills, J.C. & Gordon, J.I. A new approach for filtering noise from high-density oligonucleotide microarray datasets. Nucleic Acids Res. 29, E72-2 (2001).
    • (2001) Nucleic Acids Res. , vol.29
    • Mills, J.C.1    Gordon, J.I.2
  • 40
    • 0035793042 scopus 로고    scopus 로고
    • Model-based analysis of oligonucleotide arrays: Expression index computation and outlier detection
    • Li, C. & Wong, W.H. Model-based analysis of oligonucleotide arrays: expression index computation and outlier detection. Proc. Natl. Acad. Sci. USA 98, 31-36 (2001).
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 31-36
    • Li, C.1    Wong, W.H.2
  • 41
    • 0032444355 scopus 로고    scopus 로고
    • Altered ratios of alternatively spliced long and short γ2 subunit mRNAs of the γ-amino butyrate type A receptor in prefrontal cortex of schizophrenics
    • Huntsman, M.M., Tran, B.-V., Potkin, S.G., Bunney, W.E. & Jones, E.G. Altered ratios of alternatively spliced long and short γ2 subunit mRNAs of the γ-amino butyrate type A receptor in prefrontal cortex of schizophrenics. Proc. Natl. Acad. Sci. USA 95, 15066-15071 (1998).
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 15066-15071
    • Huntsman, M.M.1    Tran, B.-V.2    Potkin, S.G.3    Bunney, W.E.4    Jones, E.G.5
  • 42
    • 0041328892 scopus 로고    scopus 로고
    • Oligodendrocyte dysfunction in schizophrenia and bipolar disorder
    • Tkachev, D. et al. Oligodendrocyte dysfunction in schizophrenia and bipolar disorder. Lancet 362, 798-805 (2003).
    • (2003) Lancet , vol.362 , pp. 798-805
    • Tkachev, D.1
  • 44
    • 0347079826 scopus 로고    scopus 로고
    • Analysis of molecular profile data using generative and discriminative methods
    • Moler, E.J. et al. Analysis of molecular profile data using generative and discriminative methods. Physiol. Genomics 4, 109-126 (2000).
    • (2000) Physiol. Genomics , vol.4 , pp. 109-126
    • Moler, E.J.1
  • 45
    • 0034041299 scopus 로고    scopus 로고
    • Genomic views of the immune system
    • Staudt, L.M. & Brown, P.O. Genomic views of the immune system. Annu. Rev. Immunol. 18, 829-859 (2000).
    • (2000) Annu. Rev. Immunol. , vol.18 , pp. 829-859
    • Staudt, L.M.1    Brown, P.O.2
  • 46
    • 0034960264 scopus 로고    scopus 로고
    • Missing value estimation methods for DNA microarrays
    • Troyanskaya, O. et al. Missing value estimation methods for DNA microarrays. Bioinformatics 17, 520-525 (2001).
    • (2001) Bioinformatics , vol.17 , pp. 520-525
    • Troyanskaya, O.1
  • 47
    • 0035942271 scopus 로고    scopus 로고
    • Significance analysis of microarrays applied to the ionizing radiation response
    • Tusher, V.G., Tibshirani, R. & Chu, G. Significance analysis of microarrays applied to the ionizing radiation response. Proc. Natl. Acad. Sci. USA 98, 5116-5121 (2001).
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 5116-5121
    • Tusher, V.G.1    Tibshirani, R.2    Chu, G.3
  • 48
    • 2342598771 scopus 로고    scopus 로고
    • A high performance test of differential gene expression for oligonucleotide arrays
    • Lemon, W.J., Liyanarachchi, S. & You, M. A high performance test of differential gene expression for oligonucleotide arrays. Genome Biol. 4, R67 (2003).
    • (2003) Genome Biol. , vol.4
    • Lemon, W.J.1    Liyanarachchi, S.2    You, M.3
  • 49
    • 0042923097 scopus 로고    scopus 로고
    • Class prediction and discovery using gene microarray and proteomics mass spectroscopy data: Curses, caveats, cautions
    • Somorjai, R.L., Dolenko, B. & Baumgartner, R. Class prediction and discovery using gene microarray and proteomics mass spectroscopy data: curses, caveats, cautions. Bioinformatics 19, 1484-1491 (2003).
    • (2003) Bioinformatics , vol.19 , pp. 1484-1491
    • Somorjai, R.L.1    Dolenko, B.2    Baumgartner, R.3
  • 50
    • 84888934029 scopus 로고    scopus 로고
    • Pooling information across different studies and oligonucleotide microarray chip types to identify prognostic genes for lung cancer
    • in the press
    • Morris, J.S., Yin, G., Baggerly, K.A., Wu, C. & Zhang, L. Pooling information across different studies and oligonucleotide microarray chip types to identify prognostic genes for lung cancer. Methods Microarray Anal. in the press. III, 1-16 (2004).
    • (2004) Methods Microarray Anal. , vol.3 , pp. 1-16
    • Morris, J.S.1    Yin, G.2    Baggerly, K.A.3    Wu, C.4    Zhang, L.5
  • 51
    • 84888976854 scopus 로고    scopus 로고
    • Application of survival and multivariate methods to gene expression data combined from two sources
    • in the press
    • Robb, L., Stephens, R. & Coleman, J. Application of survival and multivariate methods to gene expression data combined from two sources. Methods Microarray Anal. III (2004), in the press.
    • (2004) Methods Microarray Anal. III
    • Robb, L.1    Stephens, R.2    Coleman, J.3
  • 53
    • 0035923521 scopus 로고    scopus 로고
    • Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses
    • Bhattacharjee, A. et al. Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses. Proc. Natl. Acad. Sci. USA 98, 13790-13795 (2001).
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 13790-13795
    • Bhattacharjee, A.1
  • 54
    • 0035923583 scopus 로고    scopus 로고
    • Diversity of gene expression in adenocarcinoma of the lung
    • Garber, M.E. et al. Diversity of gene expression in adenocarcinoma of the lung. Proc. Natl. Acad. Sci. USA 98, 13784-13789 (2001).
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 13784-13789
    • Garber, M.E.1
  • 55
    • 0036606299 scopus 로고    scopus 로고
    • Molecular profiling of non-small cell lung cancer and correlation with disease-free survival
    • Wigle, D.A. et al. Molecular profiling of non-small cell lung cancer and correlation with disease-free survival. Cancer Res. 62, 3005-3008 (2002).
    • (2002) Cancer Res. , vol.62 , pp. 3005-3008
    • Wigle, D.A.1
  • 56
    • 18544365698 scopus 로고    scopus 로고
    • Gene-expression profiles predict survival of patients with lung adenocarcinoma
    • Beer, D.G. et al. Gene-expression profiles predict survival of patients with lung adenocarcinoma. Nature Med. 8, 816-824 (2002).
    • (2002) Nature Med. , vol.8 , pp. 816-824
    • Beer, D.G.1
  • 57
    • 0037007033 scopus 로고    scopus 로고
    • Analysis of cell cycle-specific gene expression in human cells as determined by microarrays and double-thymidine block synchronization
    • Shedden, K. & Cooper, S. Analysis of cell cycle-specific gene expression in human cells as determined by microarrays and double-thymidine block synchronization. Proc. Natl. Acad. Sci. USA 99, 4379-4384 (2002).
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 4379-4384
    • Shedden, K.1    Cooper, S.2
  • 58
    • 0141504252 scopus 로고    scopus 로고
    • Experimental determination and system level analysis of essential genes in Escherichia coli MG1655
    • Gerdes, S.Y. et al. Experimental determination and system level analysis of essential genes in Escherichia coli MG1655. J. Bacteriol. 185, 5673-5684 (2003).
    • (2003) J. Bacteriol. , vol.185 , pp. 5673-5684
    • Gerdes, S.Y.1
  • 59
    • 0037172948 scopus 로고    scopus 로고
    • Transcriptional response of Saccharomyces cerevisiae to DNA-damaging agents does not identify the genes that protect against these agents
    • Birrell, G.W. et al. Transcriptional response of Saccharomyces cerevisiae to DNA-damaging agents does not identify the genes that protect against these agents. Proc. Natl. Acad. Sci. USA 99, 8778-8783 (2002).
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 8778-8783
    • Birrell, G.W.1
  • 60
    • 0242298316 scopus 로고    scopus 로고
    • DNA helicase gene interaction network define using synthetic lethality analyzed by microarray
    • Ooi, S.L., Shoemaker, D.D. & Boeke, J.D. DNA helicase gene interaction network define using synthetic lethality analyzed by microarray. Nature Genet. 35, 277-286 (2003).
    • (2003) Nature Genet. , vol.35 , pp. 277-286
    • Ooi, S.L.1    Shoemaker, D.D.2    Boeke, J.D.3
  • 61
    • 0035799707 scopus 로고    scopus 로고
    • Lethality and centrality in protein networks
    • Jeong, H., Mason, S.P., Barabasi, A.-L. & Oltvai, Z.N. Lethality and centrality in protein networks. Nature411, 41-42 (2001).
    • (2001) Nature , vol.411 , pp. 41-42
    • Jeong, H.1    Mason, S.P.2    Barabasi, A.-L.3    Oltvai, Z.N.4
  • 63
    • 0030598904 scopus 로고    scopus 로고
    • The role of the genome project in determining gene function: Insights from model organisms
    • Miklos, G.L.G. & Rubin, G.M. The role of the genome project in determining gene function: insights from model organisms. Cell 86, 521-529 (1996).
    • (1996) Cell , vol.86 , pp. 521-529
    • Miklos, G.L.G.1    Rubin, G.M.2
  • 64
    • 0030962307 scopus 로고    scopus 로고
    • Gene expression profiles in normal and cancer cells
    • Zhang, L. et al. Gene expression profiles in normal and cancer cells. Science 276, 1268-1272 (1997).
    • (1997) Science , vol.276 , pp. 1268-1272
    • Zhang, L.1
  • 66
    • 0028004289 scopus 로고
    • Mice lacking vimentin develop and reproduce without an obvious phenotype
    • Colucci-Guyon, E. et al. Mice lacking vimentin develop and reproduce without an obvious phenotype. Cell 79, 679-694 (1994).
    • (1994) Cell , vol.79 , pp. 679-694
    • Colucci-Guyon, E.1
  • 67
    • 0030879275 scopus 로고    scopus 로고
    • A tenascin knockout with a phenotype
    • Erikson, H.P. A tenascin knockout with a phenotype. Nature Genet. 17, 5-8 (1997).
    • (1997) Nature Genet. , vol.17 , pp. 5-8
    • Erikson, H.P.1
  • 68
    • 0035875090 scopus 로고    scopus 로고
    • Differential expression of the actin-binding proteins, α-actinin-2 and -3 in different species: Implications for the evolution of functional redundancy
    • Mills, M.A. et al. Differential expression of the actin-binding proteins, α-actinin-2 and -3 in different species: implications for the evolution of functional redundancy. Hum. Mol. Genet. 10, 1335-1346 (2001).
    • (2001) Hum. Mol. Genet. , vol.10 , pp. 1335-1346
    • Mills, M.A.1
  • 69
    • 0028071119 scopus 로고
    • Analbumenia: Three cases resulting from different point mutations in the albumin gene
    • Watkins, S. et al. Analbumenia: three cases resulting from different point mutations in the albumin gene. Proc. Natl. Acad. Sci. USA 91, 9417-9421 (1994).
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 9417-9421
    • Watkins, S.1
  • 70
    • 0037227643 scopus 로고    scopus 로고
    • The sigmoidal curve of cancer
    • Stock, R.P. & Bialy, H. The sigmoidal curve of cancer. Nature Biotechnol. 21, 13-14 (2003).
    • (2003) Nature Biotechnol. , vol.21 , pp. 13-14
    • Stock, R.P.1    Bialy, H.2
  • 71
    • 0019869334 scopus 로고
    • The molecular basis of dominance
    • Kacser, H. & Burns, J.A. The molecular basis of dominance. Genetics 97, 639-666 (1981).
    • (1981) Genetics , vol.97 , pp. 639-666
    • Kacser, H.1    Burns, J.A.2
  • 72
    • 22144476180 scopus 로고    scopus 로고
    • Basins of attraction in network dynamics
    • (eds. Schlosser, G. & Wagner, G.P.) (Chicago University Press, Chicago
    • Wuensche, A. Basins of attraction in network dynamics. in Modularity in Development and Evolution (eds. Schlosser, G. & Wagner, G.P.) 1-17 (Chicago University Press, Chicago, Illinois, 2004).
    • (2004) Modularity in Development and Evolution , pp. 1-17
    • Wuensche, A.1
  • 73
    • 0030669030 scopus 로고    scopus 로고
    • Exploring the metabolic and genetic control of gene expression on a genomic scale
    • DeRisi, J.L., Iyer, V.R. & Brown, P.O. Exploring the metabolic and genetic control of gene expression on a genomic scale. Science 278, 680-686 (1997).
    • (1997) Science , vol.278 , pp. 680-686
    • DeRisi, J.L.1    Iyer, V.R.2    Brown, P.O.3
  • 74
    • 0030848624 scopus 로고    scopus 로고
    • A test case of correlation metric construction of a reaction pathway from measurements
    • Arkin, A., Shen, P. & Ross, J. A test case of correlation metric construction of a reaction pathway from measurements. Science 277, 1275-1279 (1997).
    • (1997) Science , vol.277 , pp. 1275-1279
    • Arkin, A.1    Shen, P.2    Ross, J.3
  • 75
    • 0037107935 scopus 로고    scopus 로고
    • From microarrays to networks: Mining expression time series
    • Dewey, T.G. From microarrays to networks: mining expression time series. Drug Discov Today 7, S170-S175 (2002).
    • (2002) Drug Discov Today , vol.7
    • Dewey, T.G.1
  • 76
    • 0842342616 scopus 로고    scopus 로고
    • A genome-wide oscillation in transcription gates DNA replication and cell cycle
    • Klevecz, R.R., Bolen, J., Forrest, G. & Murray, D.B. A genome-wide oscillation in transcription gates DNA replication and cell cycle. Proc. Natl. Acad. Sci. USA 101, 1200-1205 (2004).
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 1200-1205
    • Klevecz, R.R.1    Bolen, J.2    Forrest, G.3    Murray, D.B.4
  • 77
    • 1542288938 scopus 로고    scopus 로고
    • Global organization of metabolic fluses in the bacterium Escherichia coli
    • Almaas, E., Kovacs, B., Vicsek, T., Oltvai, Z.N. & Barabasi, A.-L. Global organization of metabolic fluses in the bacterium Escherichia coli. Nature 427, 839-843 (2004).
    • (2004) Nature , vol.427 , pp. 839-843
    • Almaas, E.1    Kovacs, B.2    Vicsek, T.3    Oltvai, Z.N.4    Barabasi, A.-L.5
  • 78
    • 0037079054 scopus 로고    scopus 로고
    • Computational systems biology
    • Kitano, H. Computational systems biology. Nature 420, 206-210 (2002).
    • (2002) Nature , vol.420 , pp. 206-210
    • Kitano, H.1
  • 80
    • 0842285841 scopus 로고    scopus 로고
    • Summing up the noise in gene networks
    • Paulsson, J. Summing up the noise in gene networks. Nature 427, 415-418 (2004).
    • (2004) Nature , vol.427 , pp. 415-418
    • Paulsson, J.1
  • 81
    • 0035233731 scopus 로고    scopus 로고
    • Integrating molecular medicine with functional proteomics: Realities and expectations
    • Miklos, G.L.G. & Maleszka, R. Integrating molecular medicine with functional proteomics: realities and expectations. Proteomics 1, 30-41 (2001).
    • (2001) Proteomics , vol.1 , pp. 30-41
    • Miklos, G.L.G.1    Maleszka, R.2
  • 82
    • 0035261653 scopus 로고    scopus 로고
    • Protein functions and biological contexts
    • Miklos, G.L.G. & Maleszka, R. Protein functions and biological contexts. Proteomics 1, 169-178 (2001).
    • (2001) Proteomics , vol.1 , pp. 169-178
    • Miklos, G.L.G.1    Maleszka, R.2
  • 83
    • 0037177589 scopus 로고    scopus 로고
    • Maneuvering in the complex path from genotype to phenotype
    • Strohman, R. Maneuvering in the complex path from genotype to phenotype. Science 296, 701-703 (2002).
    • (2002) Science , vol.296 , pp. 701-703
    • Strohman, R.1
  • 84
    • 0037866424 scopus 로고    scopus 로고
    • Leroy Hood expounds the principles, practice and future of systems biology
    • Carney, S.L. Leroy Hood expounds the principles, practice and future of systems biology. Drug Discov. Today 8, 436-438 (2003).
    • (2003) Drug Discov. Today , vol.8 , pp. 436-438
    • Carney, S.L.1
  • 85
    • 1242283920 scopus 로고    scopus 로고
    • In silico biotechnology. Era of reconstruction and interrogation
    • Palsson, B. O. In silico biotechnology. Era of reconstruction and interrogation. Curr. Opin. Biotechnol. 15, 50-51 (2004).
    • (2004) Curr. Opin. Biotechnol. , vol.15 , pp. 50-51
    • Palsson, B.O.1
  • 86
    • 0027231035 scopus 로고
    • Molecules to cognition: The latter-day lessons of levels, language and lac. Evolutionary overview of brain structure and function in some vertebrates and invertebrates
    • Miklos, G.L.G. Molecules to cognition: the latter-day lessons of levels, language and lac. Evolutionary overview of brain structure and function in some vertebrates and invertebrates. J. Neurobiol. 24, 842-890 (1993).
    • (1993) J. Neurobiol. , vol.24 , pp. 842-890
    • Miklos, G.L.G.1
  • 87
    • 0344824417 scopus 로고    scopus 로고
    • Saccharomyces cerevisiae phenotypes can be predicted by using constraint-based analysis of a genome-scale reconstructed metabolic network
    • Famili, I., Forster, J., Nielsen, J. & Palsson, B.O. Saccharomyces cerevisiae phenotypes can be predicted by using constraint-based analysis of a genome-scale reconstructed metabolic network. Proc. Natl. Acad. Sci. USA 100, 13134-13139 (2003).
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 13134-13139
    • Famili, I.1    Forster, J.2    Nielsen, J.3    Palsson, B.O.4
  • 88
    • 0345824737 scopus 로고    scopus 로고
    • Network component analysis: Reconstruction of regulatory signals in biological systems
    • Liao, J.C. et al. Network component analysis: reconstruction of regulatory signals in biological systems. Proc. Natl. Acad. Sci. USA 100, 15522-15527 (2003).
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 15522-15527
    • Liao, J.C.1
  • 89
    • 0037452576 scopus 로고    scopus 로고
    • Regulatory gene networks and the properties of the developmental process
    • Davidson, E.H., McClay, D.R. & Hood, L. Regulatory gene networks and the properties of the developmental process. Proc. Natl. Acad. Sci. USA 100, 1475-1480 (2003).
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 1475-1480
    • Davidson, E.H.1    McClay, D.R.2    Hood, L.3
  • 90
    • 0242574985 scopus 로고    scopus 로고
    • Reconciling gene expression data with known genome-scale regulatory network structures
    • Herrgard, M.J., Covert, M.W. & Palsson, B.O. Reconciling gene expression data with known genome-scale regulatory network structures. Genome Res. 13, 2423-2434 (2003).
    • (2003) Genome Res. , vol.13 , pp. 2423-2434
    • Herrgard, M.J.1    Covert, M.W.2    Palsson, B.O.3
  • 91
    • 12144287672 scopus 로고    scopus 로고
    • Systematic changes in gene expression in postmortem human brains associated with tissue pH and terminal medical conditions
    • Li, J.Z. et al. Systematic changes in gene expression in postmortem human brains associated with tissue pH and terminal medical conditions. Hum. Mol. Genet. 13, 609-616 (2004).
    • (2004) Hum. Mol. Genet. , vol.13 , pp. 609-616
    • Li, J.Z.1
  • 92
    • 0034098729 scopus 로고    scopus 로고
    • Genome annotation assessment in Drosophila melanogaster
    • Reese, M.G. et al. Genome annotation assessment in Drosophila melanogaster. Genome Res. 10, 483-501 (2000).
    • (2000) Genome Res. , vol.10 , pp. 483-501
    • Reese, M.G.1
  • 93
    • 84888939277 scopus 로고    scopus 로고
    • Use of microarray data via model-based classification in the study and prediction of survival from lung cancer
    • in the press
    • Jones, L., Ng, S.-K., Ambroise, C. & McLachlan, G. Use of microarray data via model-based classification in the study and prediction of survival from lung cancer. Methods Microarray Anal. III (2004), in the press.
    • (2004) Methods Microarray Anal. III
    • Jones, L.1    Ng, S.-K.2    Ambroise, C.3    McLachlan, G.4
  • 94
    • 12144286180 scopus 로고    scopus 로고
    • Parallel genotyping of over 10,000 SNPs using a one-primer assay on a high-density oligonucleotide array
    • Matsuzaki, H. et al. Parallel genotyping of over 10,000 SNPs using a one-primer assay on a high-density oligonucleotide array. Genome Res. 14, 414-425 (2004).
    • (2004) Genome Res. , vol.14 , pp. 414-425
    • Matsuzaki, H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.