The inhibitor of death receptor signaling, FLICE-inhibitory protein defines a new class of tumor progression factors

Journal of Experimental Medicine

Volumn 190, Issue 7, 1999, Pages 1025-1031

  Djerbi, Mounira ^a   Screpanti, Valentina ^a   Catrina, Anca Irinel ^b   Bogen, Bjarne ^c   Biberfeld, Peter ^b   Grandien, Alf ^a  

^a STOCKHOLM UNIVERSITY   (Sweden)

^b KAROLINSKA INSTITUTE   (Sweden)

^c UNIVERSITY OF OSLO   (Norway)

Author keywords

Antiapoptotic proteins; Apoptosis; Fas receptor; Herpesvirus; Lymphoma

Indexed keywords

CASPASE; FAS ANTIGEN; FAS LIGAND; INTERLEUKIN 1BETA CONVERTING ENZYME INHIBITOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; B CELL LYMPHOMA; CELL PROTECTION; CLONOGENESIS; CONTROLLED STUDY; ENZYME INACTIVATION; EXPERIMENTAL NEOPLASM; HUMAN; HUMAN CELL; HUMAN HERPESVIRUS 8; LYMPHOCYTE CLONE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FAMILY; SIGNAL TRANSDUCTION; TUMOR GROWTH; VIRUS PATHOGENESIS;

EID: 0033523684     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.190.7.1025     Document Type: Article

References (24)

1. Ashkenazi, A., and V.M. Dixit. 1998. Death receptors: signaling and modulation. Science. 281:1305-1308.
2. Chou, J.J., H. Matsuo, H. Duan, and G. Wagner. 1998. Solution structure of the RAIDD CARD and model for CARD/CARD interaction in caspase-2 and caspase-9 recruitment. Cell. 94:171-180.
3. Thornberry, N.A., and Y. Lazebnik. 1998. Caspases: enemies within. Science. 281:1312-1316.
4. Thompson, C.B. 1995. Apoptosis in the pathogenesis and treatment of disease. Science. 267:1456-1462.
5. Meinl, E., H. Fickenscher, M. Thome, J. Tschopp, and B. Fleckenstein. 1998. Anti-apoptotic strategies of lymphotropic viruses, Immunol. Today, 19:474-479.
6. Thome, M., P. Schneider, K. Hofmann, H. Fickenscher, E. Meinl, F. Neipel, C. Mattmann, K. Burns, J.-L. Bodmer, M. Schröter, et al. 1997. Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors. Nature. 386:517-521.
7. Irmler, M., M. Thome, M. Hahne, P. Schneider, K. Hofmann, V. Steiner, J.-L. Bodmer, M. Schröter, K. Burns, C. Mattman, et al. 1997. Inhibition of death receptor signals by cellular FLIP. Nature. 388:190-195.
8. Adams, J.M., and S. Cory. 1998. The Bcl-2 protein family: arbiters of cell survival. Science. 281:1322-1326.
9. Tsujimoto, Y., and C.M. Croce. 1986. Analysis of the structure, transcripts, and protein products of Bcl-2, the gene involved in human follicular lymphoma. Proc. Natl. Acad. Sci. USA. 82:7439-7443.
10. Gaidano, G., E. Castaños-Velez, and P. Biberfeld. 1999. Lymphoid disorders associated with HHV-8/KSHV infections: facts and contentions. Med. Onc. 16:8-12.
11. Kim, K.J., C. Kanellopoulos-Langevin, R.M. Merwin, D.H. Sachs, and R. Asofsky. 1979. Establishment and characterization of BALB/c lymphoma lines with B cell properties. J. Immunol. 122:549-554.
12. Kayagaki, N., N. Yamaguchi, F. Nagao, S. Matsuo, H. Maeda, K. Okumura, and H. Yagita. 1997. Polymorphism of murine Fas ligand that affects the biological activity. Proc. Natl. Acad. Sci. USA. 94:3914-3919.
13. Renne, R., W. Zhong, B. Herndier, M. McGrath, N. Abbey, D. Kedes, and D. Ganem. 1996. Lytic growth of Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) in culture. Nat. Med. 2:342-346.
14. Miller, A.D., and G.J. Rosman. 1989. Improved retroviral vectors for gene transfer and expression. Biotechniques. 7:980-990.
15. Taswell, C. 1981. Limiting dilution assays for the determination of immunocompetent cell frequencies. J. Immunol. 126: 1614-1619.
16. Nicholson, D.W., A. Ali, N.A. Thornberry, J.P. Vaillancourt, C.K. Ding, M. Gallant, Y. Gareau, P.R. Griffin, M. Labelle, Y.A. Lazebnik, et al. 1995. Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis. Nature. 376:37-43.
17. Kumar, V., T. George, Y.Y.L. Yu, J. Liu, and M. Bennet. 1997. Role of murine NK cells and their receptors in hybrid resistance. Curr. Opin. Immunol. 9:52-56.
18. Sell, S. 1996. Tumor immunity. In Immunology, Immunopathology & Immunity. J. Dolan and C. Langan, editors. Appleton & Lange, Stamford, CT. 901-968.
19. Kuwana, T., J.J. Smith, M. Muzio, V. Dixit, D.D. Newmeyer, and S. Kornbluth. 1998. Apoptosis induction by caspase-8 is amplified through the mitochondrial release of cytochrome c. J. Biol. Chem. 273:16589-16594.
20. Scaffidi, C., S. Fulda, A. Srinivasan, C. Friesen, F. Li, K.J. Tomaselli, K.M. Debatin, P.H. Krammer, and M.E. Peter. 1998. Two CD95 (Apo-1/Fas) signaling pathways. EMBO (Eur. Mol. Biol. Organ.) J. 17:1675-1687.
21. Ambrosini, G., C. Adida, and D.C. Altieri. 1997. A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma. Nat. Med. 3:917-921.
22. Golstein, P. 1997. Cell death: TRAIL and its receptors. Curr. Biol. 7:R750-R753.
23. Griffith, T.S., W.A. Chin, G.C. Jackson, D.H. Lynch, and M.Z. Kubin. 1998. Intracellular regulation of TRAIL-induced apoptosis in human melanoma cells. J. Immunol. 161: 2833-2840.
24. Owen-Schaub, L.B., K.L. van Golen, L.L. Hill, and J.E. Price. 1998. Fas and Fas ligand interactions suppress melanoma lung metastasis. J. Exp. Med. 188:1717-1723.