-
1
-
-
0028971289
-
Rel/NF-κB/IκB family: Intimate tales of association and dissociation
-
Verma IM, Stevenson JK, Schwarz EM, Van Antwerp D, Miyamoto S. Rel/NF-κB/IκB family: intimate tales of association and dissociation. Genes Dev 1995;9:2723-35.
-
(1995)
Genes Dev
, vol.9
, pp. 2723-2735
-
-
Verma, I.M.1
Stevenson, J.K.2
Schwarz, E.M.3
Van Antwerp, D.4
Miyamoto, S.5
-
2
-
-
0031897632
-
NF-κB and Rel proteins: Evolutionarily conserved mediators of immune responses
-
Ghosh S, May MJ, Kopp EB. NF-κB and Rel proteins: evolutionarily conserved mediators of immune responses. Annu Rev Immunol 1998;16:225-60.
-
(1998)
Annu Rev Immunol
, vol.16
, pp. 225-260
-
-
Ghosh, S.1
May, M.J.2
Kopp, E.B.3
-
3
-
-
0035137882
-
Control of oncogenesis and cancer therapy resistance by the transcription factor NF-κB
-
Baldwin AS. Control of oncogenesis and cancer therapy resistance by the transcription factor NF-κB. J Clin Invest 2001;107:241-6.
-
(2001)
J Clin Invest
, vol.107
, pp. 241-246
-
-
Baldwin, A.S.1
-
4
-
-
0033558215
-
The prosurvival Bcl-2 homolog Bfl-I/AI is a direct transcriptional target of NF-κB that blocks TNFα-induced apoptosis
-
Zong WX, Edelstein LC, Chen C, Bash J, Gelinas C. The prosurvival Bcl-2 homolog Bfl-I/AI is a direct transcriptional target of NF-κB that blocks TNFα-induced apoptosis. Genes Dev 1999;13:382-7.
-
(1999)
Genes Dev
, vol.13
, pp. 382-387
-
-
Zong, W.X.1
Edelstein, L.C.2
Chen, C.3
Bash, J.4
Gelinas, C.5
-
5
-
-
0032508414
-
NF-κB antiapoptosis: Induction of TRAF1 and TRAF2 and C-IAP1 and C-IAP2 to suppress caspase-8 activation
-
Wang CY, Mayo MW, Korneluk RG, Goeddel DV, Baldwin AS Jr. NF-κB antiapoptosis: induction of TRAF1 and TRAF2 and C-IAP1 and C-IAP2 to suppress caspase-8 activation. Science 1998;281:1680-3.
-
(1998)
Science
, vol.281
, pp. 1680-1683
-
-
Wang, C.Y.1
Mayo, M.W.2
Korneluk, R.G.3
Goeddel, D.V.4
Baldwin Jr., A.S.5
-
6
-
-
0035891320
-
Inhibition of JNK activation through NF-κB target genes
-
Tang G, Minemoto Y, Dibling B, et al. Inhibition of JNK activation through NF-κB target genes. Nature 2001;414:313-7.
-
(2001)
Nature
, vol.414
, pp. 313-317
-
-
Tang, G.1
Minemoto, Y.2
Dibling, B.3
-
7
-
-
0033557805
-
Rel-dependent induction of A1 transcription is required to protect B cells from antigen receptor ligation-induced apoptosis
-
Grumont RJ, Rourke IJ, Gerondakis S. Rel-dependent induction of A1 transcription is required to protect B cells from antigen receptor ligation-induced apoptosis. Genes Dev 1999;13:400-11.
-
(1999)
Genes Dev
, vol.13
, pp. 400-411
-
-
Grumont, R.J.1
Rourke, I.J.2
Gerondakis, S.3
-
8
-
-
0030885421
-
Suppression of tumor necrosis factor-induced cell death by inhibitor of apoptosis C-IAP2 is under NF-κB control
-
Chu ZL, McKinsey TA, Liu L, Gentry JJ, Malim MH, Ballard DW. Suppression of tumor necrosis factor-induced cell death by inhibitor of apoptosis C-IAP2 is under NF-κB control. Proc Natl Acad Sci U S A 1997;94:10057-62.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 10057-10062
-
-
Chu, Z.L.1
McKinsey, T.A.2
Liu, L.3
Gentry, J.J.4
Malim, M.H.5
Ballard, D.W.6
-
9
-
-
0034084163
-
Phosphorylation meets ubiquitination: The control of NF-κB activity
-
Karin M, Ben-Neriah Y. Phosphorylation meets ubiquitination: the control of NF-κB activity. Annu Rev Immunol 2000;18:621-63.
-
(2000)
Annu Rev Immunol
, vol.18
, pp. 621-663
-
-
Karin, M.1
Ben-Neriah, Y.2
-
10
-
-
0027980321
-
The ubiquitin-proteasome pathway is required for processing the NF-κB1 precursor protein and the activation of NF-κB
-
Palombella VJ, Rando OJ, Goldberg AL, Maniatis T. The ubiquitin-proteasome pathway is required for processing the NF-κB1 precursor protein and the activation of NF-κB. Cell 1994;78:773-85.
-
(1994)
Cell
, vol.78
, pp. 773-785
-
-
Palombella, V.J.1
Rando, O.J.2
Goldberg, A.L.3
Maniatis, T.4
-
11
-
-
0028148227
-
A proteasome inhibitor prevents activation of NF-κB and stabilizes a newly phosphorylated form of IκB-α that is still bound to NF-κB
-
Traenckner EB, Wilk S, Baeuerle PA. A proteasome inhibitor prevents activation of NF-κB and stabilizes a newly phosphorylated form of IκB-α that is still bound to NF-κB. EMBO J 1994;13:5433-41.
-
(1994)
EMBO J
, vol.13
, pp. 5433-5441
-
-
Traenckner, E.B.1
Wilk, S.2
Baeuerle, P.A.3
-
12
-
-
0028985191
-
In vivo stimulation of IκB phosphorylation is not sufficient to activate NF-κB
-
Alkalay I, Yaron A, Hatzubai A, et al. In vivo stimulation of IκB phosphorylation is not sufficient to activate NF-κB. Mol Cell Biol 1995;15: 1294-301.
-
(1995)
Mol Cell Biol
, vol.15
, pp. 1294-1301
-
-
Alkalay, I.1
Yaron, A.2
Hatzubai, A.3
-
13
-
-
0028985190
-
Phosphorylation of IκBα precedes but is not sufficient for its dissociation from NF-κB
-
DiDonato J, Mercuric F, Karin M. Phosphorylation of IκBα precedes but is not sufficient for its dissociation from NF-κB. Mol Cell Biol 1995;15:1302-11.
-
(1995)
Mol Cell Biol
, vol.15
, pp. 1302-1311
-
-
Didonato, J.1
Mercuric, F.2
Karin, M.3
-
14
-
-
0029976817
-
An essential role for NF-κB in preventing TNF-α-induced cell death
-
Beg AA, Baltimore D. An essential role for NF-κB in preventing TNF-α-induced cell death. Science 1996;274:782-4.
-
(1996)
Science
, vol.274
, pp. 782-784
-
-
Beg, A.A.1
Baltimore, D.2
-
15
-
-
0032980504
-
Absence of tumor necrosis factor rescues RelA-deficient mice from embryonic lethality
-
Doi TS, Marino MW, Takahashi T, et al. Absence of tumor necrosis factor rescues RelA-deficient mice from embryonic lethality. Proc Natl Acad Sci 1999; 96:2994-9.
-
(1999)
Proc Natl Acad Sci
, vol.96
, pp. 2994-2999
-
-
Doi, T.S.1
Marino, M.W.2
Takahashi, T.3
-
16
-
-
0033532386
-
The IKKβ subunit of IκB kinase (IKK) is essential for nuclear factor κB activation and prevention of apoptosis
-
Li Z-W, Chu W, Hu Y, et al. The IKKβ subunit of IκB kinase (IKK) is essential for nuclear factor κB activation and prevention of apoptosis. J Exp Med 1999;189:1839-45.
-
(1999)
J Exp Med
, vol.189
, pp. 1839-1845
-
-
Li, Z.-W.1
Chu, W.2
Hu, Y.3
-
17
-
-
0034175632
-
Severe liver degeneration and lack of NF-κB activation in NEMO/IKKβ-deficient mice
-
Rudolph D, Yen W-C, Wakeham A, et al. Severe liver degeneration and lack of NF-κB activation in NEMO/IKKβ-deficient mice. Genes Dev 2000;14:854-62.
-
(2000)
Genes Dev
, vol.14
, pp. 854-862
-
-
Rudolph, D.1
Yen, W.-C.2
Wakeham, A.3
-
18
-
-
0033596127
-
Control of apoptosis by Rel/NF-κB transcription factors
-
Barkett M, Gilmore TD. Control of apoptosis by Rel/NF-κB transcription factors. Oncogene 1999;18:6910-24.
-
(1999)
Oncogene
, vol.18
, pp. 6910-6924
-
-
Barkett, M.1
Gilmore, T.D.2
-
19
-
-
0032589089
-
NF-κB functions as both a proapoptotic and antiapoptotic regulatory factor within a single cell type
-
Lin B, Williams-Skipp C, Tao Y, et al. NF-κB functions as both a proapoptotic and antiapoptotic regulatory factor within a single cell type. Cell Death Differ 1999;6:570-82.
-
(1999)
Cell Death Differ
, vol.6
, pp. 570-582
-
-
Lin, B.1
Williams-Skipp, C.2
Tao, Y.3
-
20
-
-
0034737193
-
NF-κB activation by camptothecin. A linkage between nuclear DNA damage and cytoplasmic signaling events
-
Huang TT, Wuerzberger-Davis SM, Seufzer BJ, et al. NF-κB activation by camptothecin. A linkage between nuclear DNA damage and cytoplasmic signaling events. J Biol Chem 2000;275:9501-9.
-
(2000)
J Biol Chem
, vol.275
, pp. 9501-9509
-
-
Huang, T.T.1
Wuerzberger-Davis, S.M.2
Seufzer, B.J.3
-
21
-
-
0035452254
-
S phase dependence and involvement of NF-κB activating kinase to NF-κB activation by camptothecin
-
Habraken Y, Piret B, Piette J. S phase dependence and involvement of NF-κB activating kinase to NF-κB activation by camptothecin. Biochem Pharmacol 2001;62:603-16.
-
(2001)
Biochem Pharmacol
, vol.62
, pp. 603-616
-
-
Habraken, Y.1
Piret, B.2
Piette, J.3
-
22
-
-
1142299539
-
Isolation of p53-target genes and their functional analysis
-
Nakamura Y. Isolation of p53-target genes and their functional analysis. Cancer Sci 2004;95:7-11.
-
(2004)
Cancer Sci
, vol.95
, pp. 7-11
-
-
Nakamura, Y.1
-
23
-
-
0027359827
-
WAF1, a potential mediator of p53 tumor suppression
-
el-Deiry WS, Tokino T, Velculescu VE, et al. WAF1, a potential mediator of p53 tumor suppression. Cell 1993;75:817-25.
-
(1993)
Cell
, vol.75
, pp. 817-825
-
-
El-Deiry, W.S.1
Tokino, T.2
Velculescu, V.E.3
-
24
-
-
0034738420
-
WAF1/Cip1: More than a break to the cell cycle?
-
WAF1/Cip1: more than a break to the cell cycle? Biochim Biophys Acta 2000;1471:M43-56.
-
(2000)
Biochim Biophys Acta
, vol.1471
-
-
Dotto, G.P.1
-
25
-
-
0032573165
-
Ionizing radiation and short wavelength UV activate NF-κB through two distinct mechanisms
-
Li N, Karin M. Ionizing radiation and short wavelength UV activate NF-κB through two distinct mechanisms. Proc Natl Acad Sci U S A 1998;95:13012-7.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 13012-13017
-
-
Li, N.1
Karin, M.2
-
26
-
-
0032497587
-
A novel ionizing radiation-induced signaling pathway that activates the transcription factor NF-κB
-
Lee SJ, Dimtchev A, Lavin MF, Dritschilo A, Jung M. A novel ionizing radiation-induced signaling pathway that activates the transcription factor NF-κB. Oncogene 1998;17:1821-6.
-
(1998)
Oncogene
, vol.17
, pp. 1821-1826
-
-
Lee, S.J.1
Dimtchev, A.2
Lavin, M.F.3
Dritschilo, A.4
Jung, M.5
-
27
-
-
0029858387
-
TNF- And cancer therapy-induced apoptosis: Potentiation by inhibition of NF-κB
-
Wang C-Y, Mayo MW, Baldwin AS Jr. TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-κB. Science 1996;274:784-7.
-
(1996)
Science
, vol.274
, pp. 784-787
-
-
Wang, C.-Y.1
Mayo, M.W.2
Baldwin Jr., A.S.3
-
28
-
-
0029851617
-
Signal-induced degradation of IκBα: Association with NF-κB, the PEST sequence in IκBα are not required
-
Van Antwerp DJ, Verma IM. Signal-induced degradation of IκBα: association with NF-κB, the PEST sequence in IκBα are not required. Mol Cell Biol 1996;16:6037-45.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 6037-6045
-
-
Van Antwerp, D.J.1
Verma, I.M.2
-
29
-
-
0028899112
-
Role of Rel-related factors in control of c-myc gene transcription in receptor-mediated apoptosis of the murine B cell WEHI 231 line
-
Lee H, Arsura M, Wu M, Duyao M, Buckler AJ, Sonenshein GE. Role of Rel-related factors in control of c-myc gene transcription in receptor-mediated apoptosis of the murine B cell WEHI 231 line. J Exp Med 1995;181:1169-77.
-
(1995)
J Exp Med
, vol.181
, pp. 1169-1177
-
-
Lee, H.1
Arsura, M.2
Wu, M.3
Duyao, M.4
Buckler, A.J.5
Sonenshein, G.E.6
-
30
-
-
0037374470
-
Differential roles of RelA (p65) and c-Rel subunits of nuclear factor κB in tumor necrosis factor-related apoptosis-inducing ligand signaling
-
Chen X, Kandasamy K, Srivastava RK. Differential roles of RelA (p65) and c-Rel subunits of nuclear factor κB in tumor necrosis factor-related apoptosis-inducing ligand signaling. Cancer Res 2003;63:1059-66.
-
(2003)
Cancer Res
, vol.63
, pp. 1059-1066
-
-
Chen, X.1
Kandasamy, K.2
Srivastava, R.K.3
-
32
-
-
16244364806
-
Methylation and inhibition of expression of uPA by the RAS oncogene: Divergence of growth control and invasion in breast cancer cells
-
Pakneshan P, Szyf M, Rabbani SA. Methylation and inhibition of expression of uPA by the RAS oncogene: divergence of growth control and invasion in breast cancer cells. Carcinogenesis 2005;26:557-64.
-
(2005)
Carcinogenesis
, vol.26
, pp. 557-564
-
-
Pakneshan, P.1
Szyf, M.2
Rabbani, S.A.3
-
33
-
-
0346505340
-
The IKK NF-κB system: A treasure trove for drug development
-
Karin M, Yamamoto Y, Wang QM. The IKK NF-κB system: a treasure trove for drug development. Nat Rev Drug Discov 2004;3:17-26.
-
(2004)
Nat Rev Drug Discov
, vol.3
, pp. 17-26
-
-
Karin, M.1
Yamamoto, Y.2
Wang, Q.M.3
-
34
-
-
9244251125
-
Cell-cycle checkpoints and cancer
-
Kastan MB, Bartek J. Cell-cycle checkpoints and cancer. Nature 2004; 432:316-23.
-
(2004)
Nature
, vol.432
, pp. 316-323
-
-
Kastan, M.B.1
Bartek, J.2
-
35
-
-
0035449355
-
Cell cycle checkpoint signaling through the ATM and ATR kinases
-
Abraham RT. Cell cycle checkpoint signaling through the ATM and ATR kinases. Genes Dev 2001;15:2177-96.
-
(2001)
Genes Dev
, vol.15
, pp. 2177-2196
-
-
Abraham, R.T.1
-
36
-
-
0034707047
-
The DNA damage response: Putting checkpoints in perspective
-
Zhou BB, Elledge SJ. The DNA damage response: putting checkpoints in perspective. Nature 2000;408:433-9.
-
(2000)
Nature
, vol.408
, pp. 433-439
-
-
Zhou, B.B.1
Elledge, S.J.2
-
37
-
-
7444221823
-
Role of DNA mismatch repair in apoptotic responses to therapeutic agents
-
Meyers M, Hwang A, Wagner MW, Boothman DA. Role of DNA mismatch repair in apoptotic responses to therapeutic agents. Environ Mol Mutagen 2004; 44:249-64.
-
(2004)
Environ Mol Mutagen
, vol.44
, pp. 249-264
-
-
Meyers, M.1
Hwang, A.2
Wagner, M.W.3
Boothman, D.A.4
-
41
-
-
0033696884
-
Roles of nuclear factor-κB, p53, and p21/WAF1 in daunomycin-induced cell cycle arrest and apoptosis
-
Hellin AC, Bentires-Alj M, Verlaet M, et al. Roles of nuclear factor-κB, p53, and p21/WAF1 in daunomycin-induced cell cycle arrest and apoptosis. J Pharmacol Exp Ther 2000;295:870-8.
-
(2000)
J Pharmacol Exp Ther
, vol.295
, pp. 870-878
-
-
Hellin, A.C.1
Bentires-Alj, M.2
Verlaet, M.3
-
42
-
-
0036594890
-
The role of the cyclin-dependent kinase inhibitor p21 in apoptosis
-
Gartel AL, Tyner AL. The role of the cyclin-dependent kinase inhibitor p21 in apoptosis. Mol Cancer Ther 2002;1:639-49.
-
(2002)
Mol Cancer Ther
, vol.1
, pp. 639-649
-
-
Gartel, A.L.1
Tyner, A.L.2
-
43
-
-
0030614504
-
Regulation of NF-κB by cyclin-dependent kinases associated with the p300 coactivator
-
Perkins ND, Felzien LK, Berts JC, Leung K, Beach DH, Nabel GJ. Regulation of NF-κB by cyclin-dependent kinases associated with the p300 coactivator. Science 1997;275:523-7.
-
(1997)
Science
, vol.275
, pp. 523-527
-
-
Perkins, N.D.1
Felzien, L.K.2
Berts, J.C.3
Leung, K.4
Beach, D.H.5
Nabel, G.J.6
-
44
-
-
0034960907
-
Postrepression activation of NF-κB requires the amino-terminal nuclear export signal specific to IκBα
-
Huang TT, Miyamoto S. Postrepression activation of NF-κB requires the amino-terminal nuclear export signal specific to IκBα. Mol Cell Biol 2001; 21:4737-47.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 4737-4747
-
-
Huang, T.T.1
Miyamoto, S.2
-
45
-
-
0031594708
-
Novel IκBα proteolytic pathway in WEHI231 immature B cells
-
Miyamoto S, Seufzer BJ, Shumway SD. Novel IκBα proteolytic pathway in WEHI231 immature B cells. Mol Cell Biol 1998;18:19-29.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 19-29
-
-
Miyamoto, S.1
Seufzer, B.J.2
Shumway, S.D.3
-
46
-
-
0036315743
-
The zinc finger domain of NEMO is selectively required for NF-κB activation by UV radiation and topoisomerase inhibitors
-
Huang TT, Feinberg SL, Suryanarayanan S, Miyamoto S. The zinc finger domain of NEMO is selectively required for NF-κB activation by UV radiation and topoisomerase inhibitors. Mol Cell Biol 2002;22:5813-25.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 5813-5825
-
-
Huang, T.T.1
Feinberg, S.L.2
Suryanarayanan, S.3
Miyamoto, S.4
-
47
-
-
0032080821
-
Induction of apoptosis in MCF-7:WS8 breast cancer cells by p-lapachone
-
Wuerzberger SM, Pink JJ, Planchon SM, Byers KL, Bornmann WG, Boothman DA. Induction of apoptosis in MCF-7:WS8 breast cancer cells by p-lapachone. Cancer Res 1998;58:1876-85.
-
(1998)
Cancer Res
, vol.58
, pp. 1876-1885
-
-
Wuerzberger, S.M.1
Pink, J.J.2
Planchon, S.M.3
Byers, K.L.4
Bornmann, W.G.5
Boothman, D.A.6
-
48
-
-
0033953587
-
A nuclear export signal in the N-terminal regulatory domain of IκBα controls cytoplasmic localization of inactive NF-κB/IκBα complexes
-
Huang TT, Kudo N, Yoshida M, Miyamoto S. A nuclear export signal in the N-terminal regulatory domain of IκBα controls cytoplasmic localization of inactive NF-κB/IκBα complexes. Proc Natl Acad Sci U S A 2000;97:1014-9.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 1014-1019
-
-
Huang, T.T.1
Kudo, N.2
Yoshida, M.3
Miyamoto, S.4
-
49
-
-
1842425617
-
Evidence that C promoter-binding factor I binding is required for Notch-1 -mediated repression of activator protein-1
-
Chu J, Bresnick EH. Evidence that C promoter-binding factor I binding is required for Notch-1 -mediated repression of activator protein-1. J Biol Chem 2004; 279:12337-45.
-
(2004)
J Biol Chem
, vol.279
, pp. 12337-12345
-
-
Chu, J.1
Bresnick, E.H.2
|