A novel polyamine analog inhibits growth and induces apoptosis in human breast cancer cells

Clinical Cancer Research

Volumn 9, Issue 7, 2003, Pages 2769-2777

  Huang, Yi ^a   Hager, Erin R ^a   Phillips, Dawn L ^a   Dunn, Valerie R ^c   Hacker, Amy ^a   Frydman, Benjamin ^b   Kink, John A ^b   Valasinas, Aldonia L ^b   Reddy, Venodhar K ^b   Marton, Laurence J ^b   Casero Jr , Robert A ^a   Davidson, Nancy E ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b SLIL Biomedical Corp   (United States)

^c HOWARD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CYTOCHROME C; DRUG ANALOG; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; POLYAMINE DERIVATIVE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN C JUN; SL 11144; TRANSCRIPTION FACTOR AP 1; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BREAST CARCINOMA; CANCER CELL CULTURE; CANCER GROWTH; CANCER INHIBITION; CELL DEATH; CELL PROLIFERATION; CELL STRAIN MCF 7; CONTROLLED STUDY; CYTOPATHOGENIC EFFECT; CYTOSOL; DOSE TIME EFFECT RELATION; ENZYME ACTIVATION; ENZYME INHIBITION; FEMALE; GROWTH INHIBITION; HUMAN; HUMAN CELL; MITOCHONDRION; MOUSE; NONHUMAN; NUDE MOUSE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN DEGRADATION; UPREGULATION; XENOGRAFT;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BREAST NEOPLASMS; CASPASE 3; CASPASES; CELL DEATH; CELL DIVISION; CELL LINE, TUMOR; CELL NUCLEUS; CELL SURVIVAL; CHROMATIN; CYTOCHROMES C; CYTOPLASM; CYTOSOL; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME ACTIVATION; FEMALE; HUMANS; MICE; MICE, INBRED BALB C; MICE, NUDE; MICROSCOPY, FLUORESCENCE; MODELS, CHEMICAL; NEOPLASM TRANSPLANTATION; NUCLEOSOMES; POLY(ADP-RIBOSE) POLYMERASES; POLYAMINES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; PROTO-ONCOGENE PROTEINS C-JUN; TETRAZOLIUM SALTS; THIAZOLES; TIME FACTORS; UP-REGULATION;

EID: 12444295406     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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