1-(N-alkylamino)-11-(N-ethylamino)-4,8-diazaundecanes: Simple synthetic polyamine analogues that differentially alter tubulin polymerization

Journal of Medicinal Chemistry

Volumn 42, Issue 8, 1999, Pages 1415-1421

  Webb, Heather K ^c   Wu, Zhiqian ^a   Sirisoma, Nilantha ^a   Ha, Hyo Chol ^b   Casero Jr , Robert A ^b   Woster, Patrick M ^a  

^a WAYNE STATE UNIVERSITY   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

^c Oridigm Corporation   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 (N ALKYLAMINO) 11 (N ETHYLAMINO) 4,8 DIAZAUNDECANE; ACYLTRANSFERASE; BIS(ETHYL)NORSPERMINE; MONOCLONAL ANTIBODY; N1 (2 METHYL 1 BUTYL) N11 ETHYL 4,8 DIAZAUNDECANE; N1 (CYCLOHEPTYLMETHYL) N11 ETHYL 4,8 DIAZAUNDECANE; N1 (CYCLOPROPYLMETHYL) N11 ETHYL 4,8 DIAZAUNDECANE; PACLITAXEL; POLYAMINE; SPERMIDINE; SPERMINE; TUBULIN; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CELL CYCLE; CELL GROWTH; CYTOTOXICITY; DOSE RESPONSE; DRUG SYNTHESIS; NONHUMAN; POLYAMINE METABOLISM; POLYMERIZATION;

ANTINEOPLASTIC AGENTS; BIOPOLYMERS; CELL CYCLE; CELL DIVISION; HUMANS; IMMUNOHISTOCHEMISTRY; POLYAMINES; TUBULIN; TUMOR CELLS, CULTURED;

EID: 0033594448     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm980603+     Document Type: Article

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