Use of interleukin 15 to enhance interferon-γ production by antigen-specific stimulated lymphocytes from rhesus macaques

Journal of Immunological Methods

Volumn 279, Issue 1-2, 2003, Pages 55-67

  Calarota, Sandra A ^a   Otero, Miguel ^a   Hermanstayne, Keith ^a   Lewis, Mark ^b   Rosati, Margherita ^c   Felber, Barbara K ^c   Pavlakis, George N ^c   Boyer, Jean D ^a   Weiner, David B ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b SOUTHERN RESEARCH INSTITUTE   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

Author keywords

ELISPOT; IL 15; Interferon ; Rhesus macaques

Indexed keywords

ANTIRETROVIRUS AGENT; CD8 ANTIGEN; GAG PROTEIN; GAMMA INTERFERON; INTERLEUKIN 15; PEPTIDE; VIRUS ENVELOPE PROTEIN;

ACCURACY; ANALYTIC METHOD; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN SPECIFICITY; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; ENZYME IMMUNOASSAY; ENZYME LINKED IMMUNOSPOT ASSAY; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNE RESPONSE; IMMUNOSTIMULATION; IN VITRO STUDY; LYMPHOCYTE ACTIVATION; MONONUCLEAR CELL; NONHUMAN; PERIPHERAL CIRCULATION; PRIORITY JOURNAL; PROTEIN DETERMINATION; QUANTITATIVE ANALYSIS; RHESUS MONKEY; SIMIAN IMMUNODEFICIENCY VIRUS; T LYMPHOCYTE; VIRUS INFECTION;

HUMAN IMMUNODEFICIENCY VIRUS; MACACA; MACACA MULATTA; SIMIAE; SIMIAN IMMUNODEFICIENCY VIRUS; SIMIAN-HUMAN IMMUNODEFICIENCY VIRUS;

EID: 0142061097     PISSN: 00221759     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-1759(03)00246-1     Document Type: Article

References (31)

1. Allen T.M., Mothe B.R., Sidney J., Jing P., Dzuris J.L., Liebl M.E., Vogel T.U., O'Connor D.H., Wang X., Wussow M.C., Thomson J.A., Altman J.D., Watkins D.I., Sette A. CD8(+) lymphocytes from simian immunodeficiency virus-infected rhesus macaques recognize 14 different epitopes bound by the major histocompatibility complex class I molecule mamu-A*01: implications for vaccine deign and testing. J. Virol. 75:2001;738.
2. Amara R.R., Villinger F., Staprans S.I., Altman J.D., Montefiori D.C., Kozyr N.L., Xu Y., Wyatt L.S., Earl P.L., Herndon J.G., McClure H.M., Moss B., Robinson H.L. Different patterns of immune responses but similar control of a simian-human immunodeficiency virus 89.6 P mucosal challenge by modified vaccinia virus ankara (MVA) and DNA/MVA vaccines. J. Virol. 76:2002;7625.
3. Bass E., Jefferys R. IAVI March/April report. Warming Trends at Keystone Vaccine Conference: Talks Highlight Human Trials, T-cell Markers and Antibody Approaches:2002.
4. Casimiro D.R., Tang A., Perry H.C., Long R.S., Chen M., Heidecker G.J., Davies M.E., Freed D.C., Persaud N.V., Dubey S., Smith J.G., Havlir D., Richman D., Chastain M.A., Simon A.J., Fu T.M., Emini E.A., Shiver J.W. Vaccine-induced immune responses in rodents and nonhuman primates by use of a humanized human immunodeficiency virus type 1 pol gene. J. Virol. 76:2002;185.
5. Caulfield M.J., Wang S., Smith J.G., Tobery T.W., Liu X., Cavies M.E., Casimiro D.R., Fu T.M., Simon A., Evans R.K., Emini E.A., Shiver J. Sustained peptide-specific gamma interferon T-cell response in rhesus macaques immunized with human immunodeficiency virus gag DNA vaccine. J. Virol. 76:2002;10038.
6. Chehimi J., Marshall J.D., Salvucci O., Frank I., Chehimi S., Kawecki S., Bacheller D., Rifat S., Chouaib S. IL-15 enhances immune functions during HIV infection. J. Immunol. 158:1997;5978.
7. Fehniger T.A., Caligiuri M.A. Interleukin 15: biology and relevance to human disease. Blood. 97:2001;14.
8. Fu T.-M., Freed D.C., Trigona W.L., Guan L., Zhu L., Long R., Persaud N.V., Manson K., Dubey S., Shiver J.W. Evaluation of cytotoxic T-lymphocyte responses in human and nonhuman primate subjects infected with human immunodeficiency virus type 1 or simian/human immunodeficiency virus. J. Virol. 75:2001;73.
9. Grabstein K.H., Eisenman J., Shanebeck K., Rauch C., Srinivasan S., Fung V., Beers C., Richardson J., Shoenborn M.A., Ahdieh M., Johnson L., Alderson M.R., Watson J.D., Anderson D.M., Giri J.G. Cloning of a T cell growth factor that interacts with the β chain of the interleukin-2 receptor. Science. 264:1994;965.
10. Jennes W., Kestens L., Nixon D.F., Shacklett B.L. Enhanced ELISPOT detection of antigen-specific T cell responses from cryopreserved specimens with the addition of both IL-7 and IL-15 the Amplispot assay. J. Immunol. Methods. 270:2002;99.
11. Jin X., Bauer D.E., Tuttleton S.E., Lewin S., Gettie A., Blanchard J., Irwin C.E., Safrit J.T., Mittler J., Weinberger L., Kostrikis L.G., Zhang L., Perelson A.S., Ho D.D. Dramatic rise in plasma viremia after CD8+ T cell depletion in simian immunodeficiency virus-infected macaques. J. Exp. Med. 189:1999;991.
12. Joag S.V. Primate models of AIDS. Microbes Infect. 2:2000;223.
13. Kaech S.M., Hemby S., Kersh E., Ahmed R. Molecular and functional profiling of memory CD8 T cell differentiation. Cell. 111:2002;837.
14. Kalams S.A., Goulder P.J., Shea A.K., Jones N.G., Trocha A.K., Ogg G.S., Walker B.D. Levels of human immunodeficiency virus type 1-specific cytotoxic T-lymphocyte effector and memory responses decline after suppression of viremia with highly active antiretroviral therapy. J. Virol. 73:1999;6721.
15. Kanai T., Thomas E.K., Yasutomi Y., Letvin N.L. IL-15 stimulates the expansion of AIDS virus-specific CTL. J. Immunol. 157:1996;3681.
16. Kim J.J., Trivedi N.N., Nottingham L.K., Morrison L., Tsai A., Hu Y., Mahalingam S., Dang K., Ahn L., Doyle N.K., Wilson D.M., Chattergoon M.A., Chalian A.A., Boyer J.D., Agadjanyan M.G., Weiner D.B. Modulation of amplitude and direction of in vivo immune responses by co-administration of cytokine gene expression cassettes with DNA immunogens. Eur. J. Immunol. 28:1998;1089.
17. Kumar A., Weiss W., Tine J.A., Hoffman S.L., Rogers W.O. ELISPOT assay for detection of peptide specific interferon-γ secreting cells in rhesus macaques. J. Immunol. Methods. 247:2001;49.
18. Kuroda M.J., Schmitz J.E., Barouch D.H., Craiu A., Allen T.M., Sette A., Watkins D.I., Forman M.A., Letvin N.L. Analysis of Gag-specific cytotoxic T lymphocytes in simian immunodeficiency virus-infected rhesus monkeys by cell staining with a tetrameric major histocompatibility complex class I-peptide complex. J. Exp. Med. 187:1998;1373.
19. Lorenz H.-M., Hieronymus T., Grunke M., Manger B., Kalden J.R. Differential role for IL-2 and IL-15 in the inhibition of apoptosis in short term activated human lymphocytes. Scand. J. Immunol. 45:1997;660.
20. Maecker H.T., Dunn H.S., Suni M.A., Khatamzas E., Pitcher C.J., Bunde T., Persaud N., Trigona W., Fu T.-M., Sinclair E., Bredt B.M., McCune J.M., Maino V.C., Kern F., Picker L.J. Use of overlapping peptide mixtures as antigens for cytokine flow cytometry. J. Immunol. Methods. 255:2001;27.
21. McGraw T.P., Vowels B.R., Gershwin M.E., Gardner M.B. Cellular immune response of SIV-infected rhesus macaques. J. Med. Primatol. 19:1990;177.
22. Miller M.D., Lord C.I., Stallard V., Mazzara G.P., Letvin N.L. The gag-specific cytotoxic T lymphocytes in rhesus monkeys infected with the simian immunodeficiency virus of macaques. J. Immunol. 144:1990;122.
23. Mueller Y.M., Makar V., Bojczuk P.M., Witek J., Katsikis P.D. IL-15 enhances the function and inhibits CD95/Fas-induced apoptosis of human CD4+ and CD8+ effector-memory T cells. Int. Immunol. 15:2003;49.
24. Munroe K.J., Anderson C.A., Wu J.Y., Wyand M.S., Newman G.W., Newman M.J. Use of fixed autologous stimulator cells to correctly present human immunodeficiency virus type 1 peptides to nonhuman primate lymphocytes in proliferation and cytotoxic T-lymphocyte assays. Clin. Diagn. Lab. Immunol. 1:1994;283.
25. Newberg M.H., Kuroda M.J., Charini W.A., Miura A., Lord C.I., Schmitz J.E., Gorgone D.A., Lifton M.A., Kuus-Reichel K., Letvin N.L. A simian immunodeficiency virus nef peptide is a dominant cytotoxic T lymphocyte epitope in Indian-origin rhesus monkeys expressing the common MHC class I allele mamu-A*02. J. Virol. 301:2002;365.
26. Ogg G.S., Jin X., Bonhoeffer S., Moss P., Nowak M.A., Monard S., Segal J.P., Cao Y., Rowland-Jones S.L., Hurley A., Markowitz M., Ho D.D., McMichael A.J., Nixon D.F. Decay kinetics of human immunodeficiency virus-specific effector cytotoxic T-lymphocytes after combination antiretroviral therapy. J. Virol. 73:1999;797.
27. Schluns K.S., Williams K., Ma A., Zheng X.X., Lefrançois L. Cutting edge: requirement for IL-15 in the generation of primary and memory antigen-specific CD8 T cells. J. Immunol. 168:2002;4827.
28. Schmitz J.E., Kuroda M.J., Santra S., Sasseville V.G., Simon M.A., Lifton M.A., Racz P., Tenner-Racz K., Dalesandro M., Scallon B.J., Ghrayeb J., Forman M.A., Montefiori D.C., Rieber E.P., Letvin N.L., Reimann K.A. Control of viremia in simian immunodeficiency virus infection by CD8+ lymphocytes. Science. 283:1999;857.
29. Suni M.A., Picker L.J., Maino V.C. Detection of antigen-specific T cell cytokine expression in whole blood by flow cytometry. J. Immunol. Methods. 212:1998;89.
30. Waldmann T.A., Dubois S., Tagaya Y. Contrasting roles of IL-12 and IL-15 in the life and death of lymphocytes: implications for immunotherapy. Immunity. 14:2001;105.
31. Wee E.G.T., Patel S., McMichael A.J., Hanke T. A DNA/MVA-based candidate human immunodeficiency virus vaccine for Kenya induces multi-specific T cell responses in rhesus macaques. J. Gen. Virol. 83:2002;75.