Effects of flavonoids on cell proliferation and caspase activation in a human colonic cell line HT29: An SAR study

Journal of Medicinal Chemistry

Volumn 48, Issue 8, 2005, Pages 2790-2804

  Daskiewicz, Jean Baptiste ^a   Depeint, Flore ^b   Viornery, Lionel ^a   Bayet, Christine ^a   Comte Sarrazin, Geraldine ^a   Comte, Gilles ^a   Gee, Jennifer M ^b   Johnson, Ian T ^b   Ndjoko, Karine ^c,e   Hostettmann, Kurt ^c,e   Barron, Denis ^d  

^a UNIVERSITÉ LYON 1   (France)

^b INSTITUTE OF FOOD RESEARCH   (United Kingdom)

^c UNIVERSITY OF LAUSANNE   (Switzerland)

^d NESTLÉ RESEARCH CENTER   (Switzerland)

^e UNIVERSITY OF GENEVA   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

2',4' DIHYDROXY 5' (1,1 DIMETHYLALLYL)CHALCONE; 3 O METHYLPLATANETIN; 4 METHOXY 2',4' BETA TRIHYDROXYCHALCONE; 5 O METHYLCHRYSIN; 5 O PRENYLCHRYSIN; 5,7 DIHYDROXY 2',3,4',5' TETRAMETHOXYFLAVONE; 5,7 DIHYDROXY 3,3',4' TRIMETHOXYFLAVONE; 5,7 DIHYDROXY 3,3',4',5' TETRAMETHOXYFLAVONE; 5,7 DIHYDROXY 8 (1,1 DIMETHYLALLYL) 3,3',4' TRIMETHOXYFLAVONE; 5,7 DIHYDROXY 8 (1,1 DIMETHYLALLYL) 3,3,4' TRIMETHOXYFLAVONE; 6 (1,1 DIMETHYLALLYL)CHRYSIN; 6 PRENYLNORWOGONIN; 7 O FARNESYLCHRYSIN; 7 O GERANYLCHRYSIN; 8 (1,1 DIMETHYLALLYL) 3 O METHYLGALANGIN; 8 (1,1 DIMETHYLALLYL)CHRYSIN; 8 (1,1 DIMETHYLALLYL)GALANGIN; 8 (1,1 DIMETHYLALLYL)KAEMPFERIDE; 8 LINALYL; 8 LINALYLCHRYSIN; 8 NEROLIDYL; 8 NEROLIDYLCHRYSIN; 8 PRENYLAPIGENIN; 8 PRENYLKAEMPFEROL; 8 PRENYLQUERCETIN; APIGENIN; CASPASE; CHRYSIN; FLAVONOID; KAEMPFERIDE; KAEMPFEROL; NARINGENIN; NARINGENIN CHALCONE; POLYMETHOXYFLAVONE DERIVATIVE; QUERCETIN; UNCLASSIFIED DRUG;

ALKYLATION; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CELL STRAIN HT29; CELL SURVIVAL; DRUG ACTIVITY; DRUG HYDROXYLATION; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVATION; HUMAN; HUMAN CELL; ISOPRENYLATION; STRUCTURE ACTIVITY RELATION;

ALKYLATION; ANTINEOPLASTIC AGENTS; APOPTOSIS; CASPASES; CELL LINE, TUMOR; CELL PROLIFERATION; CHALCONE; COLONIC NEOPLASMS; ENZYME ACTIVATORS; FLAVONES; FLAVONOIDS; HUMANS; HYDROXYLATION; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 20944451921     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm040770b     Document Type: Article

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