메뉴 건너뛰기




Volumn 6, Issue 5, 2001, Pages 415-427

Matrix metalloproteinase inhibitors: Current developments and future perspectives

Author keywords

Cancer; Clinical studies; Matrix metalloproteinase inhibitors; Matrix metalloproteinases

Indexed keywords

4 DEDIMETHYLAMINOSANCYCLINE; AE 941; BATIMASTAT; CARBOPLATIN; CP 471358; CYCLOPHOSPHAMIDE; DOCETAXEL; DOXORUBICIN; ETOPOSIDE; FLUOROURACIL; FOLINIC ACID; GEMCITABINE; MARIMASTAT; MATRIX METALLOPROTEINASE; MATRIX METALLOPROTEINASE INHIBITOR; MM 1270; PACLITAXEL; PRINOMASTAT; REBIMASTAT; TANOMASTAT; UNCLASSIFIED DRUG;

EID: 0034751435     PISSN: 10837159     EISSN: None     Source Type: Journal    
DOI: 10.1634/theoncologist.6-5-415     Document Type: Article
Times cited : (142)

References (94)
  • 2
    • 0031036521 scopus 로고    scopus 로고
    • Stimulation of matrix metalloproteinase production by recombinant extracellular matrix metalloproteinase inducer from transfected Chinese hamster ovary cells
    • (1997) J Biol Chem , vol.272 , pp. 24-27
    • Guo, H.1    Zucker, S.2    Gordon, M.K.3
  • 8
    • 0023696675 scopus 로고
    • Inhibition by human recombinant tissue inhibitor of metalloproteinases of human amnion invasion and lung colonization by murine B16-F10 melanoma cells
    • (1988) Cancer Res , vol.48 , pp. 5539-5545
    • Schultz, R.M.1    Silberman, S.2    Persky, B.3
  • 14
  • 15
    • 0031935209 scopus 로고    scopus 로고
    • Stromelysin 3: An independent prognostic factor for relapse-free survival in node-positive breast cancer and demonstration of novel breast carcinoma cell expression
    • (1998) Am J Pathol , vol.152 , pp. 721-728
    • Ahmad, A.1    Hanby, A.2    Dublin, E.3
  • 19
  • 20
    • 0027251836 scopus 로고
    • A synthetic matrix metalloproteinase inhibitor decreases tumor burden and prolongs survival of mice bearing human ovarian carcinoma xenografts
    • (1993) Cancer Res , vol.53 , pp. 2087-2091
    • Davies, B.1    Brown, P.D.2    East, N.3
  • 22
  • 24
  • 25
    • 0027994031 scopus 로고
    • Matrix metalloproteinase inhibitor BB-94 (batimastat) inhibits human colon tumor growth and spread in a patient-like orthotopic model in nude mice
    • (1994) Cancer Res , vol.54 , pp. 4726-4728
    • Wang, X.1    Fu, X.2    Brown, P.D.3
  • 28
    • 0029934985 scopus 로고    scopus 로고
    • Control of lymphatic and hematogenous metastasis of a rat mammary carcinoma by the matrix metalloproteinase inhibitor batimastat (BB-94)
    • (1996) Cancer Res , vol.56 , pp. 2815-2822
    • Eccles, S.A.1    Box, G.M.2    Court, W.J.3
  • 30
    • 0032905581 scopus 로고    scopus 로고
    • Marked inhibition of tumor growth in a malignant glioma tumor model by a novel synthetic matrix metalloproteinase inhibitor AG3340
    • (1999) Clin Cancer Res , vol.5 , pp. 845-854
    • Price, A.1    Shi, Q.2    Morris, D.3
  • 32
    • 0001419987 scopus 로고    scopus 로고
    • Pharmacokinetics and efficacy of a novel matrix metalloproteinase inhibitor, AG3340, in single agent and combination therapy against B16-F10 melanoma tumors developing in the lung after IV-tail vein implantation in C57BL/6 mice
    • (1998) Proc Am Assoc Cancer Res , vol.39
    • Neri, A.1    Goggin, B.2    Kolis, S.3
  • 33
    • 0032791421 scopus 로고    scopus 로고
    • Marked antiangiogenic and antitumor efficacy of AG3340 in chemoresistant human non-small cell lung cancer tumors: Single agent and combination chemotherapy studies
    • (1999) Clin Cancer Res , vol.5 , pp. 1905-1917
    • Shalinsky, D.R.1    Brekken, J.2    Zou, H.3
  • 41
    • 0002750508 scopus 로고    scopus 로고
    • A dose-finding study of marimastat, an oral matrix metalloproteinase inhibitor, in patients with advanced ovarian cancer
    • (1996) Ann Oncol , vol.7 , Issue.SUPPL. 5 , pp. 68
    • Poole, C.1    Adams, M.2    Barley, V.3
  • 46
    • 14444284598 scopus 로고    scopus 로고
    • Combined analysis of studies of the effects of the matrix metalloproteinase inhibitor marimastat on serum tumor markers in advanced cancer: Selection of a biologically active and tolerable dose for longer-term studies
    • (1998) Clin Cancer Res , vol.4 , pp. 1101-1109
    • Nemunaitis, J.1    Poole, C.2    Primrose, J.3
  • 52
    • 0002287775 scopus 로고    scopus 로고
    • Anti-invasive and anti-metastatic activity of the novel MMP inhibitor BAY 12-9566 in subcutaneous and orthotopic models using the human colon carcinoma, HCT 116
    • (1998) Ann Oncol , vol.9 , Issue.SUPPL. 2 , pp. 75
    • Flynn, C.1    Bull, C.2    Matherne, C.3
  • 53
    • 0001845325 scopus 로고    scopus 로고
    • Activity of the matrix metalloproteinase inhibitor BAY 12-9566 against murine subcutaneous and metastatic in vivo models
    • (1998) Ann Oncol , vol.9 , Issue.SUPPL. 2 , pp. 75
    • Hibner, B.1    Bull, C.2    Flynn, C.3
  • 57
    • 0034489694 scopus 로고    scopus 로고
    • A Phase I dose escalating study of matrix metalloproteinase inhibitor BAY 12-9566 administered orally in patients with advanced solid turnouts
    • (2000) Ann Oncol , vol.11 , pp. 1579-1584
    • Hirte, H.1    Goel, R.2    Major, P.3
  • 59
    • 0033986165 scopus 로고    scopus 로고
    • Phase I and pharmacological study of the specific matrix metalloproteinase inhibitor BAY 12-9566 on a protracted oral daily dosing schedule in patients with solid malignancies
    • (2000) J Clin Oncol , vol.18 , pp. 178-186
    • Rowinsky, E.K.1    Humphrey, R.2    Hammond, L.A.3
  • 71
    • 0000100112 scopus 로고    scopus 로고
    • A phase I study of the matrix metalloproteinase inhibitor, marimastat, administered concurrently with carboplatin, to patients with relapsed ovarian cancer
    • (1998) Proc Am Soc Clin Oncol , vol.17
    • Adams, M.1    Thomas, H.2
  • 76
    • 0002815897 scopus 로고    scopus 로고
    • Phase I study of AG3440, a matrix metalloproteinase inhibitor, in combination with mitoxantrone/prednisone in patients having advanced prostate cancer
    • (1998) Ann Oncol , vol.9 , Issue.SUPPL. 2 , pp. 74
    • Wilding, G.1    Small, E.2    Ripple, G.3
  • 86
    • 0011475179 scopus 로고    scopus 로고
    • A multicenter, randomized, double-blind, placebo controlled trial of marimastat in patients with glioblastoma multiforme or gliosarcoma following completion of conventional first-line treatment
    • (2001) Proc Am Soc Clin Oncol , vol.20
    • Phuphanich, S.1    Levin, V.A.2    Yung, W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.