Examination of changes in connective tissue macromolecular components of large white pig skin following application of Lewisite vapour

Journal of Applied Toxicology

Volumn 24, Issue 1, 2004, Pages 37-46

  Lindsay, Christpher D ^a   Hambrook, Joy L ^a   Brown, Roger F R ^a   Platt, Jan C ^a   Knight, Robert ^a   Rice, Paul ^a  

^a Biomedical Sciences   (United Kingdom)

Author keywords

Collagen; Electrophoresis; Immunoblotting; Laminin; Lewisite; Pig skin

Indexed keywords

ALKYLATING AGENT; COLLAGEN TYPE 3; COLLAGEN TYPE 4; GLYCOPROTEIN; LAMININ; LEWISITE; MUSTARD GAS;

ALKYLATION; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BASEMENT MEMBRANE; CELL TYPE; CONNECTIVE TISSUE; CONTROLLED STUDY; DEGRADATION; DERMIS; DERMOEPIDERMAL JUNCTION; IMMUNOHISTOCHEMISTRY; MACROMOLECULE; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN CROSS LINKING; PROTEIN DEGRADATION; SKIN DEFECT; SWINE; TISSUE REGENERATION; VAPOR;

ANIMALS; ARSENICALS; CHEMICAL WARFARE AGENTS; COLLAGEN TYPE III; COLLAGEN TYPE IV; CONNECTIVE TISSUE; ELECTROPHORESIS, POLYACRYLAMIDE GEL; EXTRACELLULAR MATRIX PROTEINS; LAMININ; SKIN; SWINE; VOLATILIZATION;

PIERIS BRASSICAE; SUS SCROFA;

EID: 0842322808     PISSN: 0260437X     EISSN: None     Source Type: Journal    
DOI: 10.1002/jat.942     Document Type: Article

References (27)

1. Abrahamson D. 1986. Recent studies on the structure and pathology of basement membranes. J. Pathol. 149: 257-278.
2. Aumailley M, Krieg T. 1996. Laminins: a family of diverse multifunctional molecules of basement membranes. J. Invest. Dermatol. 106: 209-214.
3. Beebe GW. 1960. Lung cancer in World War I veterans: possible relation to mustard-gas injury and 1918 influenza epidemic. J. Natl. Inst. Cancer 25: 1231-1252.
4. Budavari S, O'Neil MJ, Smith A, Heckelman PE. 1989. The Merck Index: an Encyclopedia of Chemicals, Drugs, and Biologicals. Merck: Rahway, NJ; 482-483.
5. Chilcott RP, Brown RFR, Rice P. 2000. Non-invasive quantification of skin injury resulting from exposure to sulphur mustard and Lewisite vapours. Burns 26: 245-250.
6. Fuji T, Kuhn K. 1971. Isolation and characterisation of pepsin-treated type III collagen from calf skin. Z. Physiol. Chem. 356: S1793-1801.
7. Glanville RW. 1987. Type IV collagen. In Structure and Function of Collagen Types, Mayne R, Burgeson RE (eds). Academic Press: New York; 43-47.
8. Goldman M, Dacre J. 1989. Lewisite: its chemistry, toxicology and biological effects. Rev. Environ. Contam. 110: 75-115.
9. Hascall VC, Kimura JH. 1982. Proteoglycans: isolation and characterisation. Methods. Enzymol. 82: 769-799.
10. Katz SI. 1984. The epidermal basement membrane zone: structure, ontogeny and role in disease. J. Am. Acad. Dermatol. 11: 1025-1037.
11. King RJ, Peters BP, Monteiro-Riviere NA. 1994. Laminin in the cutaneous basement membrane as a potential target in lewisite vesication. Toxicol. Appl. Pharmacol. 126: 164-173.
12. Kleinman HK, Cannon FB, Laurie GW. 1985. Biological activities of laminin. J. Cell. Biochem. 27: 317-325.
13. Lam DGK, Rice P, Brown RFR. 2002. The treatment of Lewisite burns with laser debridement - 'lasablation.' Burns 28: 19-25.
14. Lindsay CD, Rice P. 1995. Changes in connective tissue macromolecular components of Yucatan mini-pig skin following application of sulphur mustard. Hum. Exp. Toxicol. 14: 341-348.
15. Lindsay CD, Upshall DG. 1995. The generation of a human dermal equivalent to assess the potential contribution of human dermal fibroblasts to the sulphur mustard-induced vesication response. Hum. Exp. Toxicol. 14: 580-586.
16. Lindsay CD, Rice P. 1996. Assessment of the biochemical effects of percutaneous exposure of sulphur mustard in an in vitro human skin system. Hum. Exp. Toxicol. 15: 237-244.
17. Miller EJ, Gay S. 1982. Collagen: an overview. Methods Enzymol. 82: 3-32.
18. Miller EJ, Rhodes RK. 1982. Preparation and characterisation of the different types of collagen. Methods Enzymol. 82: 33-64.
19. Naghii MR. 2002. Sulfur mustard intoxication, oxidative stress, and antioxidants. Mil. Med. 167: 573-575.
20. Odermatt E, Furthmayer H, Timpl R, Rohde M, Ott V, Engel J. 1982. Shape, domain structure, and flexibility of laminin. In New Trends in Basement Membrane Research, Kuehn K, Schoene H-H, Timpl R (eds). Raven Press: New York; 79.
21. Papirmeister B, Feister AJ, Robinson SI, Ford RD. 1991. Medical Defense against Mustard Gas. CRC Press: Boca Raton, FL.
22. Rice P, Brown RFR. 1999. The development of Lewisite vapour induced lesions in the domestic white pig. Int. J. Exp. Pathol. 80: 59-67.
23. Sidell FR, Urbanetti JS, Smith WJ, Hurst CG. 1996. Vesicants. In Textbook of Military Medicine, Part I - Medical Aspects of Chemical and Biological Warfare, Sidell FR, Takafuji ET, Franz DR (eds). TMM Publications, Walter Reed Army Medical Center: Washinton, DC; 197-228.
24. Smith WJ. 2002. Vesicant agents and antivesicant medical countermeasures: clinical toxicology and psychological implications. Mil. Psychol. 14: 145-157.
25. Timpl R, Rohde H, Risteli L, Ott U, Robey PG, Martin GR. 1982. Laminin. Methods Enzymol. 82: 831-837.
26. Trammel GL. 1992. Toxicodynamics of organoarsenic chemical warfare agents. In Chemical Warfare Agents, Somani SM (ed). Academic Press: San Diego, CA; 255-270.
27. Tryggvason K, Hoyhtya M, Salo T. 1987. Proteolytic degradation of extracellular matrix in tumour invasion. Biochim. Biophys. Acta 907: 191-217.