Gene therapy approaches for cartilage injury and osteoarthritis

Current Medicinal Chemistry: Anti-Inflammatory and Anti-Allergy Agents

Volumn 4, Issue 3, 2005, Pages 265-279

  Gelse, K ^a,b   Aigner, Thomas ^a   Stove J ^c   Schneider, H ^b  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^b UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^c UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Cartilage repair; Cytokines; Gene transfer; Growth factors; Mesenchymal stem cells; Osteoarthritis; Tissue engineering

Indexed keywords

ADENOVIRUS VECTOR; BETA GALACTOSIDASE; BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN 4; CASPASE INHIBITOR; CHONDROITIN SULFATE; COLLAGEN; EPIDERMAL GROWTH FACTOR; FIBROBLAST GROWTH FACTOR; GLUCOSAMINE SULFATE; GROWTH DIFFERENTIATION FACTOR 5; GROWTH FACTOR; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 10; INTERLEUKIN 11; INTERLEUKIN 13; INTERLEUKIN 4; LENTIVIRUS VECTOR; LIPOSOME; MATRIX METALLOPROTEINASE 14; MATRIX METALLOPROTEINASE INHIBITOR; NAKED DNA; NITRIC OXIDE SYNTHASE INHIBITOR; NONSTEROID ANTIINFLAMMATORY AGENT; OSTEOGENIC PROTEIN 1; PARATHYROID HORMONE RECEPTOR; PARVOVIRUS VECTOR; PLATELET DERIVED GROWTH FACTOR; POLYMER; PROTEIN BCL 2; RECOMBINANT INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; RETROVIRUS VECTOR; SMAD6 PROTEIN; SMAD7 PROTEIN; SOMATOMEDIN C; TELOMERASE REVERSE TRANSCRIPTASE; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TISSUE INHIBITOR OF METALLOPROTEINASE 2; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR SOX5; TRANSCRIPTION FACTOR SOX6; TRANSCRIPTION FACTOR SOX9; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA CONVERTING ENZYME INHIBITOR; TUMOR NECROSIS FACTOR ALPHA RECEPTOR; UNCLASSIFIED DRUG;

ARTICULAR CARTILAGE; CARTILAGE DEGENERATION; CELL BASED GENE THERAPY; CELL TRANSPLANTATION; CHONDROGENESIS; DNA MODIFICATION; DNA VECTOR; DRUG HALF LIFE; DRUG MECHANISM; DRUG USE; FIBROSIS; FREQUENCY ANALYSIS; GENE THERAPY; GENE TRANSFER; HEALTH CARE COST; HERPES SIMPLEX VIRUS; HUMAN; IN VIVO STUDY; INFLAMMATION; MURINE LEUKEMIA VIRUS; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; ORTHOPEDIC SURGERY; OSTEOARTHRITIS; PHENOTYPE; REVIEW; RHEUMATOID ARTHRITIS; STEM CELL; SURGICAL TECHNIQUE; TARGET CELL; TISSUE GRAFT; TISSUE GROWTH; TISSUE INJURY; TISSUE REPAIR; TREATMENT OUTCOME; VIRAL GENE DELIVERY SYSTEM;

EID: 20844455595     PISSN: 15680142     EISSN: None     Source Type: Journal    
DOI: 10.2174/1568014054065203     Document Type: Review

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