Chondrogenic potential of adipose tissue-derived stromal cells in vitro and in vivo

Biochemical and Biophysical Research Communications

Volumn 290, Issue 2, 2002, Pages 763-769

  Erickson, Geoffrey R ^a,b   Gimble, Jeffrey M ^c   Franklin, Dawn M ^d   Rice, Henry E ^a   Awad, Hani ^a   Guilak, Farshid ^a,b,e  

^a DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Department of Biomedical Engineering ^*  (United States)

^c Artecel Sciences   (United States)

^d Zen Bio Inc   (United States)

^e DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Adipose tissue; Cartilage; Chondrocyte; Differentiation; Mesenchymal stem cell; Multipotent; Pluripotent; Stem cell; Stroma; Tissue engineering

Indexed keywords

ALGINIC ACID; CHONDROITIN 4 SULFATE; COLLAGEN TYPE 2; COLLAGEN TYPE 6;

ADIPOSE TISSUE CELL; ANIMAL EXPERIMENT; ARTICLE; CARTILAGE MATRIX; CELL CULTURE; CELL GROWTH; CELL ISOLATION; CHONDROGENESIS; CONTROLLED STUDY; CULTURE MEDIUM; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; NUDE MOUSE; PRIORITY JOURNAL; STROMA CELL; SYNTHESIS; TISSUE ENGINEERING;

MUS MUSCULUS;

EID: 0036293498     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.2001.6270     Document Type: Article

References (45)

1. Treatment of deep cartilage defects in the knee with autologous chondrocyte transplantation
2. Effect of cultured autologous chondrocytes on repair of chondral defects in a canine model
3. Neocartilage formation in vitro and in vivo using cells cultured on synthetic biodegradable polymers
4. Cultivation of cell-polymer cartilage implants in bioreactors
5. Mesenchymal cell-based repair of large, full-thickness defects of articular cartilage
6. Treatment of articular cartilage defects of the knee with autologous chondrocyte implantation
7. Current concepts in the treatment of articular cartilage defects
8. Effects of harvest and selected cartilage repair procedures on the physical and biochemical properties of articular cartilage in the canine knee
9. Chondrocyte differentiation
10. Uno, nessuno e centomila: Searching for the identity of mesodermal progenitors
11. Chondroprogenitor cells of synovial tissue
12. Transforming growth factor-beta 1 stimulates chondrogenesis and inhibits osteogenesis in high density culture of periosteum-derived cells
13. The function of adipocytes in the bone marrow stroma: An update
14. Marrow stromal stem cells
15. Mesenchymal stem cells in bone development, bone repair, and skeletal regeneration therapy
16. Expression of the human chondrocyte phenotype in vitro
17. The chondrogenic potential of human bone-marrow-derived mesenchymal progenitor cells
18. Adipose tissue engineering: The future of breast and soft tissue reconstruction following tumor resection
19. Multilineage cells from human adipose tissue: Implications for cell-based therapies
20. Differential regulation of peroxisome proliferator activated receptor gamma1 (PPARgamma1) and PPARgamma2 messenger RNA expression in the early stages of adipogenesis
21. Thiazolidinediones and glucocorticoids synergistically induce differentiation of human adipose tissue stromal cells: Biochemical, cellular, and molecular analysis
22. De novo cartilage generation using calcium alginate-chondrocyte constructs
23. ’Nude,’ a new hairless gene with pleiotropic effects in the mouse
24. Dedifferentiated chondrocytes reexpress the differentiated collagen phenotype when cultured in agarose gels
25. Expression of a stable articular cartilage phenotype without evidence of hypertrophy by adult human articular chondrocytes in vitro
26. Reexpression of cartilage-specific genes by dedifferentiated human articular chondrocytes cultured in alginate beads
27. Adipogenic potential of human adipose derived stromal cells from multiple donors is heterogeneous
28. Adipose-derived stromal cells - Their utility and potential in bone formation
29. Surface protein characterization of human adipose tissue-derived stromal cells
30. Animal cell shape changes and gene expression
31. Proteoglycan core protein and type II collagen gene expressions are not correlated with cell shape changes during low density chondrocyte cultures
32. Proteoglycan and collagen synthesis are correlated with actin organization in dedifferentiating chondrocytes
33. Modulation and reexpression of the chondrocyte phenotype: Mediation by cell shape and microfilament modification
34. Formation of cartilage-like spheroids by micromass cultures of murine C3h10t1/2 cells upon treatment with transforming growth factor-beta-1
35. Cellular interactions and signaling in cartilage development
36. Transforming growth factor beta 1 stimulates type II collagen expression in cultured periosteum-derived cells
37. Specificity, diversity, and regulation in TGF-beta superfamily signaling
38. In vitro chondrogenesis of bone marrow-derived mesenchymal progenitor cells
39. Gelatin-based resorbable sponge as a carrier matrix for human mesenchymal stem cells in cartilage regeneration therapy
40. Embryonic stem cell-derived chondrogenic differentiation in vitro: Activation by BMP-2 and BMP-4
41. Internalization of the hyaluronan receptor CD44 by chondrocytes
42. Functional tissue engineering: The role of biomechanics
43. Culture and growth characteristics of chondrocytes encapsulated in alginate beads
44. Phenotypic stability of bovine articular chondrocytes after long-term culture in alginate beads