Therapeutic monoclonal antibodies: A short historical perspective, a lot of engineering, and... some clinical successes;Anticorps monoclonaux à usage thérapeutique: Un peu d'histoire, beaucoup d'ingénierie, et ... quelques succès cliniques

Transfusion Clinique et Biologique

Volumn 12, Issue 2 SPEC. ISS., 2005, Pages 114-122

  Siberil, S ^a,b   Dutertre, C A ^a,b   Boix, C ^a   Teillaud, J L ^a  

^a INSERM   (France)

^b Laboratoire Français du Fractionnement et des Biotechnologies   (France)

Author keywords

Antibody dependent cell cytotoxicity; Chimeric antibody; Fc region; Fusion protein; Glycosylation; Humanized antibody; Humanized mouse; Monoclonal antibody; Phage display; Single chain Fv

Indexed keywords

ABCIXIMAB; ADALIMUMAB; ALEMTUZUMAB; BASILIXIMAB; BEVACIZUMAB; CETUXIMAB; DACLIZUMAB; EDRECOLOMAB; EFALIZUMAB; GEMTUZUMAB OZOGAMICIN; IBRITUMOMAB TIUXETAN; INFLIXIMAB; MONOCLONAL ANTIBODY; OKT 3; OMALIZUMAB; PALIVIZUMAB; RITUXIMAB; TOSITUMOMAB I 131; TRASTUZUMAB;

ALLERGY; BINDING AFFINITY; BIOENGINEERING; CANCER; CARDIOVASCULAR DISEASE; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG INDUSTRY; GENOMICS; GRAFT VERSUS HOST REACTION; HUMAN; IMMUNOGENICITY; IMMUNOSUPPRESSIVE TREATMENT; INFECTION; INFLAMMATION; NONHUMAN; PHAGE DISPLAY; PROTEOMICS; REVIEW; SIDE EFFECT; SKIN DISEASE;

EID: 20444428321     PISSN: 12467820     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tracli.2005.04.016     Document Type: Short Survey

References (69)

1. J.W. Littlefield Selection of hybrids from matings of fibroblasts in vitro and their presumed recombinants Sci. 145 1964 709 710
2. G. Köhler, and C. Milstein Continuous cultures of fused cells secreting antibody of predefined specificity Nature 256 1975 495 497
3. S. Fazekas de St Groth, and D. Scheidegger Production of monoclonal antibodies: strategy and tactics J. Immunol. Methods 35 1980 1 21
4. G. Pontecorvo Production of mammalian somatic cell hybrids by means of polyethylene-glycol treatment Somat. Cell Genet. 1 1975 397 400
5. M.D. Hulett, and P.M. Hogarth Molecular basis of Fc receptor function Adv. Immunol. 57 1994 1 127
6. H. Aguila, R.R. Pollock, G. Spira, and M.D. Scharff The production of more useful monoclonal antibodies. II. The use of somatic-cell genetic and recombinant DNA technology to tailor-make monoclonal antibodies Immunol. Today 7 1986 380 383
7. J.L. Teillaud, C. Desaymard, A.M. Giusti, B. Haseltine, R.R. Pollock, and D.E. Yelton Monoclonal antibodies reveal the structural basis of antibody diversity Sci. 222 1984 721 726
8. G. Spira, A. Bargellesi, J.L. Teillaud, and M.D. Scharff The identification of monoclonal class switch variants by Sib Selection and an Elisa assay J. Immunol. Methods 74 1984 307 315
9. L. Olsson, and H.S. Kaplan Human-human hybridomas producing monoclonal antibodies of predefined antigenic specificity Proc. Natl. Acad. Sci. USA 77 1980 5429 5431
10. M. Steinitz, G. Klein, S. Koskimies, and O. Makela EB virus induced B lymphocyte cell lines producing specific antibodies Nature 269 1977 420 422
11. P. Casali, G. Inghiriami, M. Nakamura, T. Davies, and A.L. Notkins Human monoclonals from antigen-specific selection of B lymphocytes and transformation by EBV Sci. 234 1986 476 479
12. D. Kozbor, A. Lagarde, and J.C. Roder Human hybridomas constructed with antigen-specific Epstein-Barr virus-transformed cell lines Proc. Natl. Acad. Sci. USA 79 1982 6651 6655
13. W.L. Carroll, K. Thielemans, J. Dilley, and R. Levy Mouse x human hetero-hybridomas as fusion partners with human B cell tumors J. Immunol. Methods 89 1986 61 72
14. A. Karpas, A. Dremucheva, and B.H. Czepulkowski A human myeloma cell line suitable for the generation of human monoclonal antibodies Proc. Natl. Acad. Sci. USA 98 2001 1799 1804
15. C.A. Borrebaeck, and S.A. Möller In vitro immunization. Effect of growth and differentiation factors on antigen-specific cell activation and production of monoclonal antibodies to autologous antigens and immunogens J. Immunol. 136 1986 3710 3715
16. C.A. Borrebaeck Strategy for the production of human monoclonal antibodies using in vitro activated B cells J. Immunol. Methods 123 1989 157 165
17. J. Banchereau, P. de Paoli, A. Valle, E. Garcia, and F. Rousset Long-term human B cell lines dependent on interleukin-4 and antibody to CD40 Sci. 251 1989 70 72
18. E. Traggiai, S. Becker, and K. Subbarao An efficient method to make human monoclonal antibodies from memory B cells: potent neutralization of SARS coronavirus Nat. Med. 8 2004 871 875
19. E. Traggiai, L. Chicha, and L. Mazzucchelli Development of a human adaptative immune system in cord blood cell-tranplantated mice Sci. 304 2004 104 107
20. S.L. Morrison, M.J. Johnson, L.A. Herzenberg, and V.T. Oi Chimeric human antibody molecules: mouse antigen-binding domains with human constant region domains Proc. Natl. Acad. Sci. USA 81 1984 6851 6855
21. S.I. Takeda, T. Naito, K. Hama, T. Noma, and T. Honjo Construction of chimaeric processed immunoglobulin genes containing mouse variable and human constant region sequences Nature 314 1985 452 454
22. M.S. Co, and C. Queen Humanized antibodies for therapy Nature 351 1991 501 502
23. C. Queen, W.P. Schneider, H.E. Selick, P.W. Payne, N.F. Landolfi, and J.F. Duncan 1989, A humanized antibody that binds to the interleukin 2 receptor Proc. Natl. Acad. Sci. USA 86 1989 10029 10035
24. J. McCafferty, A.D. Griffiths, G. Winter, and D.J. Chiswell Phage antibodies: filamentous phage displaying antibody variable domains Nature 348 1990 552 554
25. T. Clackson, H.R. Hoogenboom, S. Griffiths, and G. Winter Making antibody fragments using phage display libraries Nature 352 1991 624 628
26. W.D. Huse, L. Sastry, S.A. Iverson, A.S. Kang, M.M. Alting, and D.R. Burton Generation of a large combinatorial library of the immunoglobulin repertoire in phage lambda Sci. 246 1989 1275 1281
27. G.P. Smith Filamentous fusion phage: novel expression vectors that display cloned antigens on the virion surface Sci. 228 1985 1315 1317
28. A. Skerra, and A. Plückthun Assembly of a functional immunoglobulin Fv fragment in Escherichia coli Sci 240 1988 1038 1041
29. R.E. Bird, K.D. Hardman, and J.W. Jacobson Single-chain antigen-binding proteins Sci 242 1988 423 426
30. J.S. Huston, D. Levinson, and M. Mudgett-Hunter Protein engineering of antibody binding sites: Recovery of specific activity in an anti-digoxin single-chain Fv analogue produced in Escherichia coli Proc. Natl. Acad. Sci. USA 85 1988 5879 5883
31. A. Plückthun, and A. Skerra Expression of functional antibody Fv and Fab fragments in Escherichia coli Methods Enzymol. 178 1989 497 504
32. E.S. Ward, D. Gussow, A.D. Griffiths, P.T. Jones, and G. Winter Binding activities of single immunoglobulin variable domains secreted from Escherichia coli Nature 341 1989 544 546
33. N. Lonberg, L.D. Taylor, and F.A. Harding Antigen-specific human antibodies from mice comprising four distinct genetic modifications Nature 368 1994 856 859
34. L.L. Green, M.C. Hardy, and C.E. Maynard-Currie Antigen-specific human monoclonal antibodies from mice engineered with human Ig heavy and light chain YACs Nat. Genet. 7 1994 13 21
35. K. Tomizuka, T. Shinohara, and H. Yoshida Double trans-chromosomic mice: maintenance of two individual human chromosome fragments containing Ig heavy and kappa loci and expression of fully human antibodies Proc. Natl. Acad. Sci. USA 97 2000 722 727
36. M. Torres, R. May, M.D. Scharff, and A. Casadevall Variable-region- identical antibodies differing in isotype demonstrate differences in fine specificity and idiotype J. Immunol. 174 2005 2132 2142
37. A. Wright, and S.L. Morrison Antibody variable region glycosylation: biochemical and clinical effects Springer Semin. Immunopathol. 15 1993 259 273
38. M.A. Roguska, J.T. Pedersen, and C.A. Keddy Humanization of murine monoclonal antibodies through variable domain resurfacing Proc. Natl. Acad. Sci. USA 91 1994 969 973
39. S. Delagrave, J. Catalan, and C. Sweet Effects of humanization by variable domain resurfacing on the antiviral activity of a single-chain antibody against respiratory syncytial virus Protein Eng. 12 1999 357 362
40. H.R. Hoogenboom, and G. Winter By-passing immunisation: human antibodies from synthetic repertoires of germline VH genes segments rearranged in vitro J. Mol. Biol. 227 1992 381 388
41. A.D. Griffiths, S.C. Williams, and O. Hartley Isolation of high affinity human antibodies directly from large synthetic repertoires EMBO J. 13 1994 3245 3260
42. J. de Kruif, L. Terstappen, E. Boel, and T. Logtenberg Rapid selection of cell subpopulation-specific human monoclonal antibodies from a synthetic phage antibody library Proc. Natl. Acad. Sci. USA 92 1995 3938 3942
43. H.H. Hogrefe, R.L. Mullinax, A.E. Lovejoy, B.N. Hay, and J.A. Sorge A bacteriophage lambda vector for the cloning and expression of immunoglobulin Fab fragments on the surface of filamentous phage Gene 128 1993 119 126
44. T.J. Vaughan, A.J. Williams, and K. Pritchard Human antibodies with sub-nanomolar affinities isolated from a large non-immunized phage display library Nat. Biotechnol. 14 1996 309 314
45. F. Geoffroy, R. Sodoyer, and L. Aujame A new phage display system to construct multicombinatorial libraries of very large antibody repertoires Gene 151 1994 109 113
46. H.R. Hoogenboom Overview of antibody phage-display technology and its applications Methods Mol. Biol. 178 2002 1 37
47. K.A. Chester, R.H. Begent, and L. Robson Phage libraries for generation of clinically useful antibodies Lancet 343 1994 455 456
48. L. Aujame, R. Sodoyer, and J.L. Teillaud Phage display and antibody engineering: a French overview Trends Biotechnol. 15 1997 155 157
49. R.E. Hawkins, S.J. Russell, and G. Winter Selection of phage antibodies by binding affinity: mimicking affinity maturation J. Mol. Biol. 226 1992 889 896
50. S.J. Cumbers, G.T. Williams, and S.L. Davies Generation and iterative affinity maturation of antibodies in using hypermutating B-cell lines Nat. Biotechnol. 20 2002 1129 1134
51. J. Hanes, C. Schaffitzel, A. Knappik, and A. Plückthun Picomolar affinity antibodies from a fully synthetic naive library selected and evolved by ribosome display Nat. Biotechnol. 18 2000 1287 1292
52. E.T. Boder, and K.D. Wittrup Yeast surface display for screening combinatorial polypeptide libraries Nat. Biotechnol. 15 1997 537 553
53. M.J. Feldhaus, R.W. Siegel, and L.K. Opresko Flow-cytometric isolation of human antibodies from a nonimmune Saccharomyces cerevisiae surface display library Nat. Biotechnol. 21 2003 163 170
54. L.M. Weiner, and G.P. Adams New approaches to antibody therapy Oncogene 19 2000 6144 6151
55. J.M. Reichert Monoclonal antibodies in the clinic Nat. Biotechnol. 19 2001 819 822
56. M.A. van Dijk, and J.G.J. van de Winkel Human antibodies as next generation therapeutics Curr. Opin. Chem. Biol. 5 2001 368 374
57. M. Berger, V. Shankar, and A. Vafai Therapeutic applications of monoclonal antibodies Am. J. Med. Sci. 324 2002 14 30
58. D.M. Segal, G.J. Weiner, and L.M. Weiner Bispecific antibodies in cancer therapy Cur:Opinion in Immunol 11 1999 558 562
59. M.L. Simoons Effect of glycoprotein IIb/IIIa receptor blocker Abciximab on outcome in patients with acute coronary syndromes without early coronary revascularisation: the GUSTO IV-ACS randomised trial Lancet 357 2001 1915 1924
60. J. Baselga Phase I and II clinical trials of trastuzumab Ann. Oncol. 12 Suppl 1 2001 S49 S55
61. I. Treish, R. Schwartz, and C. Lindley Pharmacology and therapeutic use of trastuzumab in breast cancer Am. J. Health Syst. Pharm. 57 2000 2063 2076
62. D.J. Slamon, B. Leyland-Jones, and S. Shak Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2 N. Engl. J. Med. 344 2001 783 792
63. B. Coiffier Rituximab in combination with CHOP improves survival in elderly patients with aggressive non-Hodgkin's lymphoma Semin. Oncol. 29 Suppl 6 2002 18 22
64. A.J. Grillo-Lopez Rituximab: an insider's historical perspective Semin. Oncol. 27 2000 9 16
65. P.C. Taylor, R.O. Williams, and R.N. Maini Immunotherapy for rheumatoid arthritis Curr. Opin. Immunol. 13 2001 611 616
66. W. Busse, J. Corren, and B.Q. Lanier Omalizumab, anti-IgE recombinant humanized monoclonal antibody, for the treatment of severe allergic asthma J. Allergy Clin. Immunol. 108 2001 184 190
67. S. Biocca, M.S. Neuberger, and A. Cattaneo Expression and targeting of intracellular antibodies in mammalian cells EMBO J. 9 1990 101 108
68. W.A. Marasco, W.A. Haseltine, and S.Y. Chen Design, intracellular expression, and activity of a human anti-human immunodeficiency virus type 1 gp120 single-chain antibody Proc. Natl. Acad. Sci. USA 90 1993 7889 7893
69. ras promotes tumor regression Cancer Res. 58 1998 1170 1176