The development of potent and selective bisarylmaleimide GSK3 inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 4, 2005, Pages 899-903

  Engler, Thomas A ^a   Malhotra, Sushant ^a   Burkholder, Timothy P ^a   Henry, James R ^a   Mendel, David ^a   Porter, Warren J ^a   Furness, Kelly ^a   Diefenbacher, Clive ^a   Marquart, Angela ^a   Reel, Jon K ^a   Li, Yihong ^a   Clayton, Joshua ^a   Cunningham, Brian ^a   McLean, Johnathan ^a   O'Toole, John C ^a   Brozinick, Joseph ^a   Hawkins, Eric ^a   Misener, Elizabeth ^a   Briere, Daniel ^a   Brier, Richard A ^a   Wagner, Jill R ^a   Campbell, Robert M ^a   Anderson, Bryan D ^a   Vaughn, Renee ^a   Bennett, Donald B ^a   Meier, Timothy I ^a   Cook, James A ^a   more..

^a ELI LILLY AND COMPANY   (United States)

Author keywords

Bisarylmaleimides; GSK3 Inhibitors

Indexed keywords

GLUCOSE; GLYCOGEN SYNTHASE KINASE 3 INHIBITOR; MALEIMIDE DERIVATIVE; TAU PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG POTENCY; DRUG SELECTIVITY; DRUG SYNTHESIS; ENZYME INHIBITION; GLUCOSE BLOOD LEVEL; IC 50; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PROTEIN PHOSPHORYLATION; RAT;

EID: 20144388396     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2004.12.063     Document Type: Article

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