Effect of surfactant HLB and different formulation variables on the properties of poly-D,L-lactide microspheres of naltrexone prepared by double emulsion technique

Journal of Microencapsulation

Volumn 22, Issue 2, 2005, Pages 139-151

  Dinarvand, Rassoul ^a   Moghadam, S H ^a   Sheikhi, A ^a   Atyabi, F ^a  

^a TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

HLB; Microencapsulation; Microspheres; Naltrexone; Poly(D,L lactide)

Indexed keywords

EMULSIFYING AGENT; MICROSPHERE; NALTREXONE; OPIATE ANTAGONIST; POLYLACTIC ACID; POLYSORBATE 20; POLYSORBATE 80; SODIUM CHLORIDE; SOLVENT; SORBITAN LAURATE; SORBITAN OLEATE; SURFACTANT; WATER OIL CREAM;

AQUEOUS SOLUTION; ARTICLE; CHEMICAL STRUCTURE; CONTROLLED STUDY; DRUG FORMULATION; EMULSION; ENCAPSULATION; EVAPORATION; HYDROPHILICITY; LIPOPHILICITY; MORPHOLOGY; PARTICLE SIZE; POROSITY; SURFACE PROPERTY; TRANSPORT KINETICS;

ABSORPTION; DRUG COMPOUNDING; EMULSIFYING AGENTS; HEXOSES; MICROSCOPY, ELECTRON, SCANNING; MICROSPHERES; NALTREXONE; NARCOTIC ANTAGONISTS; PARTICLE SIZE; POLYESTERS; SODIUM CHLORIDE; SURFACE-ACTIVE AGENTS;

EID: 20144366605     PISSN: 02652048     EISSN: None     Source Type: Journal    
DOI: 10.1080/02652040400026392     Document Type: Article

References (38)

1. Al-Maaieh A, Flanagan DR. 2001. Salt and co-solvent effects on ionic drug loading into microspheres using an O/W method. Journal of Controlled Release 70:169-181.
2. Anderson JM, Shive MS. 1997. Biodegradation and biocompatibility of PLA and PLGA microspheres. Advanced Drug Delivery Reviews 28:5-24.
3. Blanco-Prieto MJ, Fattal E, Gulik A, Dedieu JC, Roques, BP. 1997. Characterization and morphological analysis of a cholecystokinin derivative peptide-loaded poly(lactide-co-glycolide) microspheres prepared by a water-in-oil-in-water emulsion solvent evaporation method. Journal of Controlled Release 43:81-87.
4. Blanco-Prieto MJ, Leo E, Delie F, Gulik A, Couvreur P, Fattal E. 1996. Study of the influence of several stabilizing agents on the entrapment and in vitro release of pBC 264 from poly(lactide-co-glycolide) microspheres prepared by a w/o/w solvent evaporation method. Pharmaceutical Research 13:1127-1129.
5. Capan Y, Woo BH, Gebrekidan S, Ahmed S, DeLuca PP. 1999. Influence of formulation parameters on the characteristics of poly(D,L-lactide-co-glycolide) microspheres containing poly(L-lysine) complexed plasmid DNA. Journal of Controlled Release 60:279-286.
6. Carrio, A, Schwach G, Coudane J, Vert M. 1995. Preparation and degradation of surfactant-free PLAGA microspheres. Journal of Controlled Release 37:113-121.
7. Chen XQ, Yang YY, Wang L, Chung TS. 2001. Effects of inner water volume on the peculiar surface morphology of microspheres fabricated by double emulsion technique. Journal of Microencapsulation 18:637-649.
8. Chong-Kook K, Seong-Cheol K, Hee-Jong S, Kyoung MK, Kyoung-Hee O, Yong-Bok L, In-Joon O. 1995. Preparation and characterization of cytarabine-loaded W/O/W multiple emulsion. International Journal of Pharmaceutics 124:61-67.
9. Coombes AGA, Yeh MK, Lavelle EC, Davis SS. 1998. The control of protein release from poly(DL-lactide co-glycolide) microparticles by variation of the external aqueous phase surfactant in the water-in-oil-in-water method. Journal of Controlled Release 52:311-320.
10. Crotts G, Park TG. 1995. Preparation of porous and nonporous biodegradable polymeric hollow microspheres. Journal of Controlled Release 35:91-105.
11. De Rosa G, Iommelli R, La Rotonda MI, Miro A, Quaglia, F. 2000. Influence of the co-encapsulation of different non-ionic surfactants on the properties of PLGA insulin-loaded microspheres. Journal of Controlled Release 69:283-295.
12. Dinarvand R, Moghadam SH, Mohammadyari-Fard L, Atyabi F. 2003. Preparation of biodegradable microspheres and matrix devices containing naltrexone. AAPS PharmSciTech 4:article 34.
13. Freitas S, Walz A, Merkle HP, Gander B. 2003. Solvent extraction employing a static micromixer: a simple, robust and versatile technology for the microencapsulation of proteins. Journal of Microencapsulation 20:67-85.
14. Gabor F, Ertl B, Wirth M, Mallinger R. 1999. Ketoprofen - poly(D,L-lactic-co-glycolic acid) microspheres: influence of manufacturing parameters and type of polymer on the release characteristics. Journal of Microencapsulation 16:1-12.
15. Garti N, Aserin A. 1996. Double emulsions stabilized by macromolecular surfactants. Advances in Colloid and Interface Science 65:37-69.
16. Han K, Lee KD, Gao ZG, Park JS. 2001. Preparation and evaluation of poly(L-lactic acid) microspheres containing rhEGF for chronic gastric ulcer healing. Journal of Controlled Release 75:259-269.
17. He P, Davis SS, Illum L. 1999. Sustained release chitosan microspheres prepared by novel spray drying methods. Journal of Microencapsulation 16:343-355.
18. Herrmann J, Bodmeier R. 1995a. Somatostatin containing biodegradable microspheres prepared by a modified solvent evaporation method based on w/o/w multiple emulsions. International Journal of Pharmaceutics 126:129-138.
19. Herrmann J, Bodmeier R. 1995b. The effect of particle microstructure on the somatostatin release from poly(lactide) microspheres prepared by a W/O/W solvent evaporation method. Journal of Controlled Release 36:63-71.
20. Jain RA. 2000. The manufacturing techniques of various drug loaded biodegradable poly(lactide-co-glycolide) (PLGA) devices. Biomaterials 21:2475-2490.
21. Jeffery H, Davis SS, O'Hagan DT. 1993. Preparation and characterization of poly(lactide-co-glycolide) microparticles, II: entrapment of a model protein using a (water in oil) in water emulsion solvent evaporation technique. Pharmaceutical Research 10:362-368.
22. Lee JH, Park TG, Choi HK. 2000. Effect of formulation and processing variables on the characteristics of microspheres for water-soluble drugs prepared by w/o/o double emulsion solvent diffusion method. International Journal of Pharmaceutics 196:75-83.
23. Maa YF, Hsu CC. 1997. Effect of primary emulsions on microsphere size and protein-loading in the double emulsion process. Journal of Microencapsulation 14:225-241.
24. Nihant N, Schugens C, Grandfils C, Jerome R, Teyssie P. 1994. Polylactide microparticles prepared by double emulsion/evaporation technique. I. Effect of primary emulsion stability. Pharmaceutical Research 11:1479-1484.
25. Obeidat WM, Price JC. 2003. Viscosity of polymer solution phase and other factors controlling the dissolution of theophylline microspheres prepared by the emulsion solvent evaporation method. Journal of Microencapsulation 20:57-65.
26. Ogawa Y, Yamamoto M, Okada H, Yashiki T, Shimamoto T. 1988. A new technique to efficiently entrap leuprolide acetate into microcapsules of polylactic acid or co-poly (lactic/glycolic) acid. Chemical and Pharmaceutical Bulletin 36:1095-1103.
27. Rojas J, Pinto-Alphandary H, Leo E, Pecquet S, Couvreur P, Fattal E. 1999a. Optimization of the encapsulation and release of beta-lactoglobulin entrapped in poly(D,L-lactide-co-glycolide) microspheres. International Journal of Pharmaceutics 183:67-71.
28. Rojas J, Pinto-Alphandary H, Leo E, Pecquet S, Couvreur P, Gulik A, Fattal E. 1999b. A polysorbate-based non-ionic surfactant can modulate loading and release of beta-lactoglobulin entrapped in multiphase poly (D,L-lactide-co-glycolide) microspheres. Pharmaceutical Research 16:255-260.
29. Sah H. 1997. Microencapsulation techniques using ethyl acetate as a dispersed solvent: effects of its extraction rate on the characteristics of PLGA microspheres. Journal of Controlled Release 47:233-245.
30. Sajeev C, Vinay G, Archna R, Saha RN. 2002. Oral controlled release formulation of diclofenac sodium by microencapsulation with ethyl cellulose. Journal of Microencapsulation 19:753-760.
31. Sturesson C, Carlfors J. 2000. Incorporation of protein in PLG-microspheres with retention of bioactivity. Journal of Controlled Release 67:171-178.
32. Uddin MS, Hawlader MNA, Zhu HZ. 2001. Microencapsulation of ascorbic acid: effect of process variables on product characteristics. Journal of Microencapsulation 18:199-209.
33. Wan JP, Yang YY, Chung TS, Tan D, Ng S, Heller J. 2001. POE-PEG-POE tri-block copolymeric microspheres containing protein: II. Polymer erosion and protein release mechanism. Journal of Controlled Release 75: 129-141.
34. Yang YY, Chia HH, Chung TS. 2000. Effect of preparation temperature on the characteristics and release profiles of PLGA microspheres containing protein fabricated by double-emulsion solvent extraction/evaporation method. Journal of Controlled Release 69:81-96.
35. Yang YY, Wan JP, Chung TS, Pallathadka PK, Ng S, Heller J. 2001. POE-PEG-POE triblock copolymeric microspheres containing protein. I. preparation and characterization. Journal of Controlled Release 75:115-128.
36. Yolles S, Eldridge JE, Leafe TD, Woodland JH, Blake DR, Meyer FJ. 1973. Long-acting delivery systems for narcotic antagonists. Advances in Experimental Medicine and Biology 47:177-180.
37. Yolles S, Eldridge JE, Woodland JHR. 1970. New biodegradable drug delivery system. Polymers News 1:9-10.
38. Youan BBC, Benoit MA, Baras B, Gillard J. 1999. Protein-loaded poly(e-caprolactone) microparticles. I. Optimization of the preparation by (water-in-oil)-in water emulsion solvent evaporation. Journal of Microencapsulation 16:587-599.