Effect of formulation and processing variables on the characteristics of microspheres for water-soluble drugs prepared by w/o/o double emulsion solvent diffusion method

International Journal of Pharmaceutics

Volumn 196, Issue 1, 2000, Pages 75-83

  Lee, Jung Hwa ^a   Park, Tae Gwan ^b   Choi, Hoo Kyun ^a  

^a Chosun University   (South Korea)

^b Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

Author keywords

Acrylic microspheres; Acrylic resin; Release profile; w o o Double emulsion solvent diffusion method; Water soluble drug

Indexed keywords

CORN OIL; DICHLOROMETHANE; EUDRAGIT; PARACETAMOL; POLYSORBATE 80; PROPRANOLOL; SORBITAN OLEATE; TACRINE;

ARTICLE; DIFFUSION; DRUG FORMULATION; DRUG SOLUBILITY; EMULSION; MICROENCAPSULATION; PH; PRIORITY JOURNAL; TEMPERATURE;

ACETAMINOPHEN; ACRYLIC RESINS; CORN OIL; DIFFUSION; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG COMPOUNDING; EMULSIONS; METHYLENE CHLORIDE; MICROSPHERES; POLYMETHACRYLIC ACIDS; PROPRANOLOL; SOLVENTS; SURFACE-ACTIVE AGENTS; TACRINE; TEMPERATURE; THEOPHYLLINE; WATER;

EID: 0004612028     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(99)00440-8     Document Type: Article

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