Inhibition of cholesterol production but not of nonsterol isoprenoid products induces neuronal cell death

Journal of Neurochemistry

Volumn 72, Issue 6, 1999, Pages 2278-2285

  Michikawa, Makoto ^a   Yanagisawa, Katsuhiko ^a  

^a NATIONAL CENTER FOR GERIATRICS AND GERONTOLOGY   (Japan)

Author keywords

Migrating very low density lipoprotein; 3 Hydroxy 3 methylglutaryl coenzyme A reductase inhibitor; Cholesterol; Compactin; Isoprenoid products; Neuronal cell death

Indexed keywords

COMPACTIN; ISOPRENOID; SQUALENE; SQUALESTATIN; VERY LOW DENSITY LIPOPROTEIN;

ANIMAL CELL; ARTICLE; CELL DEATH; CELL GROWTH; CELL PROLIFERATION; CELL VIABILITY; CHOLESTEROL METABOLISM; COMPETITIVE INHIBITION; DNA SYNTHESIS INHIBITION; DRUG EFFECT; ESTERIFICATION; GROWTH INHIBITION; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; RAT; SYNAPTOGENESIS;

3T3 CELLS; ACETATES; ANIMALS; APOPTOSIS; BICYCLO COMPOUNDS, HETEROCYCLIC; CELL SURVIVAL; CEREBRAL CORTEX; CHOLESTEROL; EMBRYO; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; KINETICS; LIPOPROTEINS, VLDL; LOVASTATIN; MEVALONIC ACID; MICE; NEURONS; PC12 CELLS; RABBITS; RATS; RATS, SPRAGUE-DAWLEY; SQUALENE; TRICARBOXYLIC ACIDS;

EID: 0032973711     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1999.0722278.x     Document Type: Article

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