Ligand binding to the human MT2 melatonin receptor: The role of residues in transmembrane domains 3, 6, and 7

Biochemical and Biophysical Research Communications

Volumn 332, Issue 3, 2005, Pages 726-734

  Mazna, Petr ^a   Berka, Karel ^b   Jelinkova, Irena ^a   Balik, Ales ^a   Svoboda, Petr ^a   Obsilova, Veronika ^a   Obsil, Tomas ^b   Teisinger, Jan ^a  

^a INSTITUTE OF PHYSIOLOGY   (Czech Republic)

^b CHARLES UNIVERSITY   (Czech Republic)

Author keywords

G protein coupled receptor; Homology modeling; MT2 melatonin receptor; Site directed mutagenesis

Indexed keywords

2 IODOMELATONIN; MELATONIN RECEPTOR; NITROGEN; RECEPTOR BLOCKING AGENT; RECEPTOR PROTEIN;

ARTICLE; BINDING AFFINITY; BINDING ASSAY; CELL LINE; HORMONE BINDING; HUMAN; HUMAN CELL; LIGAND BINDING; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; RECEPTOR BINDING;

AMINO ACID SUBSTITUTION; BINDING SITES; CELL LINE; HUMANS; KINETICS; LIGANDS; MELATONIN; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; PROTEIN STRUCTURE, TERTIARY; RECEPTOR, MELATONIN, MT2; RECOMBINANT PROTEINS;

EID: 19744373593     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2005.05.017     Document Type: Article

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