Role of the extracellular loops of the thyrotropin-releasing hormone receptor: Evidence for an initial interaction with thyrotropin-releasing hormone

Biochemistry

Volumn 36, Issue 50, 1997, Pages 15670-15676

  Perlman, Jeffrey H ^a,d   Colson, Anny Odile ^b   Jain, Rahul ^c   Czyzewski, Bryan ^a   Cohen, Louis A ^c   Osman, Roman ^b   Gershengorn, Marvin C ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b CITY UNIVERSITY OF NEW YORK   (United States)

^c NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^d Department of Obstetrics Gynecology   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTIRELIN; PROTIRELIN RECEPTOR;

ANIMAL CELL; ARTICLE; BINDING KINETICS; CELL STRAIN COS1; COMPUTER MODEL; CONTROLLED STUDY; HORMONE RECEPTOR INTERACTION; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; BINDING SITES; COMPUTER SIMULATION; COS CELLS; GTP-BINDING PROTEINS; HYDROGEN BONDING; KINETICS; LIGANDS; MICE; MODELS, MOLECULAR; MUTAGENESIS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; RECEPTORS, THYROTROPIN-RELEASING HORMONE; THYROTROPIN-RELEASING HORMONE; TRANSFECTION; TYROSINE;

ANIMALIA;

EID: 0031444103     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9713310     Document Type: Article

References (32)

1. Strader, C. D., Fong, T. M., Tota, M. R., Underwood, D., and Dixon, R. A. F. (1994) Annu. Rev. Biochem. 63, 101-132.
2. Laakkonen, L., Guarnieri, F., Perlman, J. H., Gershengorn, M. C., and Osman, R. (1996) Biochemistry 35, 7651-7663.
3. Van Rhee, A. M., and Jacobson, K. A. (1996) Drug Dev. Res. 37, 1-38.
4. Perlman, J. H., Laakkonen, L. J., Guarnieri, F., Osman, R., and Gershengorn, M. C. (1996) Biochemistry 35, 7643-7650.
5. Perlman, J. H., Laakkonen, L., Osman, R., and Gershengorn, M. C. (1994) J. Biol. Chem. 269, 23383-23386.
6. Han, B. M., and Tashjian, A. H., Jr. (1995) Biochemistry 34, 13412-13422.
7. Baldwin, J. M. (1993) EMBO J. 12, 1693-1703.
8. Strader, C. D., Fong, T. M., Graziano, M. P., and Tota, M. R. (1995) FASEB J. 9, 745-754.
9. Schwartz, T. W. (1994) Curr. Opin. Biotechnol. 5, 434-444.
10. Han, B. M., and Tashjian, A. H., Jr. (1995) Mol. Endocrinol. 9, 1708-1719.
11. Uchida, I., Saito, A., Yasuda, A., Iwata, K., Hari, H., Hara, K., Matsushita, M., Anami, K., Haruta, J., and Furukawa, N. (1993) Chem. Abstr. 119, 117836.
12. Straub, R. E., Frech, G. C., Joho, R. H., and Gershengorn, M. C. (1990) Proc. Natl. Acad. Sci. U.S.A. 87, 9514-9518.
13. Gershengorn, M. C., and Thaw, C. N. (1991) Endocrinology 128, 1204-1206.
14. Perlman, J. H., Wang, W., Nussenzveig, D. R., and Gershengorn, M. C. (1995) J. Biol. Chem. 270, 24682-24685.
15. Perlman, J. H., Thaw, C. N., Laakkonen, L., Bowers, C. Y., Osman, R., and Gershengorn, M. C. (1994) J. Biol. Chem. 269, 1610-1613.
16. Perlman, J. H., Laakkonen, L., Osman, R., and Gershengorn, M. C. (1995) Mol. Pharmacol. 47, 480-484.
17. Vale, W., Rivier, J., and Burgus, R. (1971) Endocrinology 89, 1485-1488.
18. Limbird, L. E. (1986) Cell surface receptors: A short course on theory and methods, Martinus Nijhoff Publishing, Boston, Dordrecht, and Lancaster.
19. Brooks, B. R., Bruccoleri, R. E., Olafson, B. D., States, D. J., Swaminathan, S., and Karplus, M. (1983) J. Comput. Chem. 4, 187-217.
20. Kirkpatrick, S., Gelatt, C. D., Jr., and Vecchi, M. P. (1983) Science 220, 671-680.
21. Colson, A. O., Perlman, J. H., Smolyar, A., Gershengorn, M. C., and Osman, R. (1997) Static and dynamic roles of extracellular loops in G-protein coupled receptors: A mechanism for sequential binding of thyrotropin-releasing hormone to its receptor, Biophys. J. (in press).
22. Hinkle, P. M., and Kinsella, P. A. (1982) J. Biol. Chem. 257, 5462-5470.
23. Wells, J. A. (1990) Biochemistry 29, 8509-8517.
24. LiCata, V. J., and Ackers, G. K. (1995) Biochemistry 34, 3133-3139.
25. Mildvan, A. S., Weber, D. J., and Kuliopulos, A. (1992) Arch. Biochem. Biophys. 294, 327-340.
26. Gershengorn, M. C., and Osman, R. (1996) Physiol. Rev. 76, 175-191.
27. Xie, Y.-B., Wang, H., and Segaloff, D. L. (1990) J. Biol. Chem. 265, 21411-21414.
28. Ji, I., and Ji, T. H. (1991) J. Biol. Chem. 266, 13076-13079.
29. Stroop, S. D., Kuestner, R. E., Serwold, T. F., Chen, L., and Moore, E. E. (1995) Biochemistry 34, 1050-1057.
30. Monteclaro, F. S., and Charo, I. F. (1996) J. Biol. Chem. 271, 19084-19092.
31. Turner, P. R., Bambino, T., and Nissenson, R. A. (1996) J. Biol. Chem. 271, 9205-9208.
32. Perlman, J. H., Nussenzveig, D. R., Osman, R., and Gershengorn, M. C. (1992) J. Biol. Chem. 267, 24413-24417.