Molecular modeling of human MT2 melatonin receptor: The role of Val204, Leu272 and Tyr298 in ligand binding

Journal of Neurochemistry

Volumn 91, Issue 4, 2004, Pages 836-842

  Mazna, Petr ^a   Obsilova, Veronika ^a   Jelinkova, Irena ^a   Balik, Ales ^a   Berka, Karel ^b   Sovova, Zofie ^c   Ettrich, Rüdiger ^c   Svoboda, Petr ^a,b   Obsil, Tomas ^b   Teisinger, Jan ^a  

^a INSTITUTE OF PHYSIOLOGY   (Czech Republic)

^b CHARLES UNIVERSITY   (Czech Republic)

^c INSTITUTE OF LANDSCAPE ECOLOGY   (Czech Republic)

Author keywords

2 iodomelatonin; Homology modeling; Melatonin; MT2 melatonin receptor; Site directed mutagenesis

Indexed keywords

2 IODOMELATONIN; AMINO ACID; MELATONIN RECEPTOR; MEMBRANE PROTEIN; MUTANT PROTEIN; RHODOPSIN;

ARTICLE; BINDING ASSAY; CRYSTAL STRUCTURE; DNA SEQUENCE; FIBROBLAST; GENETIC CODE; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; KIDNEY CELL; LIGAND BINDING; MOLECULAR MODEL; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN INTERACTION; PROTEIN STRUCTURE; RECEPTOR BINDING; SITE DIRECTED MUTAGENESIS;

AMINO ACID SUBSTITUTION; ANIMALS; BINDING SITES; BINDING, COMPETITIVE; CATTLE; CELL LINE; COMPUTER SIMULATION; HUMANS; LIGANDS; MELATONIN; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; RECEPTOR, MELATONIN, MT1; RECEPTOR, MELATONIN, MT2; RHODOPSIN; STRUCTURE-ACTIVITY RELATIONSHIP;

BOVINAE;

EID: 20844445439     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2004.02758.x     Document Type: Article

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