Role of the ERC motif in the proximal part of the second intracellular loop and the C-terminal domain of the human prostaglandin F2α receptor (hFP-R) in G-protein coupling control

Biochemical Journal

Volumn 388, Issue 1, 2005, Pages 317-324

  Pathe Neuschäfer Rube, Andrea ^a   Neuschäfer Rube, Frank ^a   Püschel, Gerhard P ^a  

^a UNIVERSITY OF POTSDAM   (Germany)

Author keywords

Constitutively active mutant; ERC motif; G protein coupled receptor; Prostaglandin F2 receptor; Site directed mutagenesis; Structure function relationship

Indexed keywords

GLAUCOMA; INTRACELLULAR SIGNAL PATHWAYS; LIGAND BINDING; MUTANTS;

BIOCHEMISTRY; CELLS; MUTAGENESIS; SIGNALING;

PROTEINS;

FOCAL ADHESION KINASE; GUANINE NUCLEOTIDE BINDING PROTEIN; INOSITOL TRISPHOSPHATE; PROSTAGLANDIN RECEPTOR; PROTEIN PROSTAGLANDIN F2 ALPHA RECEPTOR; T CELL FACTOR PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BIOSYNTHESIS; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; MUTATIONAL ANALYSIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN MOTIF; PROTEIN STRUCTURE; RECEPTOR BINDING; SIGNAL TRANSDUCTION; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

AMINO ACID MOTIFS; AMINO ACID SUBSTITUTION; CELL LINE; GENE EXPRESSION REGULATION; GTP-BINDING PROTEINS; HUMANS; INOSITOL PHOSPHATES; MUTAGENESIS, SITE-DIRECTED; MUTATION; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, PROSTAGLANDIN; SIGNAL TRANSDUCTION;

EID: 19544367952     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20041321     Document Type: Article

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